Potential prognostic value of repulsive guidance molecules in breast cancer

Anticancer Research

Volumn 31, Issue 5, 2011, Pages 1703-1711

  Li, Jin ^a   Ye, Lin ^a   Mansel, Robert E ^a   Jiang, Wen G ^a  

^a CARDIFF UNIVERSITY SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

Breast cancer; Prognosis; Prostate cancer; RGM

Indexed keywords

HEMOJUVELIN;

ARTICLE; BREAST CANCER; CANCER RECURRENCE; CANCER SURVIVAL; CANCER TISSUE; DISTANT METASTASIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PREDICTIVE VALUE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE SECTION;

BLOTTING, WESTERN; BREAST; BREAST NEOPLASMS; CELL ADHESION MOLECULES, NEURONAL; CELLS, CULTURED; DISEASE PROGRESSION; FEMALE; GPI-LINKED PROTEINS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; IMMUNOENZYME TECHNIQUES; LYMPHATIC METASTASIS; MALE; MEMBRANE PROTEINS; NEOPLASM RECURRENCE, LOCAL; NERVE TISSUE PROTEINS; PROGNOSIS; PROSTATIC NEOPLASMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 79958162600     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Monnier PP, Sierra A, Macchi P, Deitinghoff L, Andersen JS, Mann M, Flad M, Hornberger MR, Stahl B, Bonhoeffer F and Mueller BK: RGM is a repulsive guidance molecule for retinal axons. Nature 419: 392-395, 2002.
2. Samad TA, Rebbapragada A, Bell E, Zhang Y, Sidis Y, Jeong SJ, Campagna JA, Perusini S, Fabrizio DA, Schneyer AL, Lin HY, Brivanlou AH, Attisano L and Woolf CJ: DRAGON, a bone morphogenetic protein co-receptor. J Biol Chem 280: 14122-14129, 2005.
3. Samad TA, Srinivasan A, Karchewski LA, Jeong SJ, Campagna JA, Ji RR, Fabrizio DA, Zhang Y, Lin HY, Bell E and Woolf CJ: DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties. J Neurosci 24: 2027-2036, 2004. (Pubitemid 38292816)
4. Niederkofler V, Salie R, Sigrist M and Arber S: Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system. J Neurosci 24: 808-818, 2004. (Pubitemid 38146591)
5. Papanikolaou G, Samuels ME, Ludwig EH, MacDonald ML, Franchini PL, Dube MP, Andres L, MacFarlane J, Sakellaropoulos N, Politou M, Nemeth E, Thompson J, Risler JK, Zaborowska C, Babakaiff R, Radomski CC, Pape TD, Davidas O, Christakis J, Brissot P, Lockitch G, Ganz T, Hayden MR and Goldberg YP: Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis. Nat Genet 36: 77-82, 2004. (Pubitemid 38056211)
6. Kanomata K, Kokabu S, Nojima J, Fukuda T and Katagiri T: DRAGON, a GPI-anchored membrane protein, inhibits BMP signaling in C2C12 myoblasts. Genes Cells 14: 695-702, 2009.
7. Ye L, Lewis-Russell JM, Kyanaston HG and Jiang WG: Bone morphogenetic proteins and their receptor signaling in prostate cancer. Histol Histopathol 22: 1129-1147, 2007. (Pubitemid 47470307)
8. Ye L, Bokobza SM and Jiang WG: Bone morphogenetic proteins in development and progression of breast cancer and therapeutic potential (review). Int J Mol Med 24: 591-597, 2009.
9. Ye L, Kynaston HG and Jiang WG: Bone metastasis in prostate cancer: molecular and cellular mechanisms (Review). Int J Mol Med 20: 103-111, 2007.
10. Ye L, Mason MD and Jiang WG: Bone morphogenetic protein and bone metastasis, implication and therapeutic potential. Front Biosci 16: 865-897, 2011.
11. Derynck R, Gelbart WM, Harland RM, Heldin CH, Kern SE, Massague J, Melton DA, Mlodzik M, Padgett RW, Roberts AB, Smith J, Thomsen GH, Vogelstein B and Wang XF: Nomenclature: vertebrate mediators of TGFbeta family signals. Cell 87: 173, 1996.
12. Parr C, Watkins G and Jiang WG: The possible correlation of NOTCH-1 and NOTCH-2 with clinical outcome and tumour clinicopathological parameters in human breast cancer. Int J Mol Med 14: 779-786, 2004.
13. Jiang WG, Davies G, Martin TA, Parr C, Watkins G, Mason MD, Mokbel K and Mansel RE: Targeting matrilysin and its impact on tumor growth in vivo: the potential implications in breast cancer therapy. Clin Cancer Res 11: 6012-6019, 2005. (Pubitemid 41170333)
14. Li J, Ye L, Parr C, Douglas-Jones A, Kynaston HG, Mansel RE and Jiang WG: The aberrant expression of bone morphogenetic protein 12 (BMP-12) in human breast cancer and its potential prognostic value. Gene Ther and Mol Biol 13A: 186-193, 2009.
15. Chambers AF: MDA-MB-435 and M14 cell lines: Identical but not M14 melanoma? Cancer Res 69: 5292-5293, 2009.
16. Li VS, Yuen ST, Chan TL, Yan HH, Law WL, Yeung BH, Chan AS, Tsui WY, So S, Chen X and Leung SY: Frequent inactivation of axon guidance molecule RGMA in human colon cancer through genetic and epigenetic mechanisms. Gastroenterology 137: 176-187, 2009.
17. Davies SR, Watkins G, Douglas-Jones A, Mansel RE and Jiang WG: Bone morphogenetic proteins 1 to 7 in human breast cancer, expression pattern and clinical/prognostic relevance. J Exp Ther Oncol 7: 327-338, 2008.
18. Hanavadi S, Martin TA, Watkins G, Mansel RE and Jiang WG: The role of growth differentiation factor-9 (GDF-9) and its analog, GDF-9b/BMP-15, in human breast cancer. Ann Surg Oncol 14: 2159-2166, 2007. (Pubitemid 46988265)
19. Buijs JT, Henriquez NV, van Overveld PG, van der Horst G, Que I, Schwaninger R, Rentsch C, Ten Dijke P, Cleton-Jansen AM, Driouch K, Lidereau R, Bachelier R, Vukicevic S, Clezardin P, Papapoulos SE, Cecchini MG, Lowik CW and van der Pluijm G: Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer. Cancer Res 67: 8742-8751, 2007. (Pubitemid 47437450)
20. Ye L, Bokobza S, Li J, Moazzam M, Chen J, Mansel RE and Jiang WG: Bone morphogenetic protein-10 (BMP-10) inhibits aggressiveness of breast cancer cells and correlates with poor prognosis in breast cancer. Cancer Sci 101: 2137-2144, 2010.
21. Raida M, Clement JH, Ameri K, Han C, Leek RD and Harris AL: Expression of bone morphogenetic protein 2 in breast cancer cells inhibits hypoxic cell death. Int J Oncol 26: 1465-1470, 2005.
22. Bobinac D, Maric I, Zoricic S, Spanjol J, Dordevic G, Mustac E and Fuckar Z: Expression of bone morphogenetic proteins in human metastatic prostate and breast cancer. Croat Med J 46: 389-396, 2005. (Pubitemid 40686482)
23. Alarmo EL, Rauta J, Kauraniemi P, Karhu R, Kuukasjarvi T and Kallioniemi A: Bone morphogenetic protein 7 is widely overexpressed in primary breast cancer. Genes Chromosomes Cancer 45: 411-419, 2006. (Pubitemid 43346773)
24. Alarmo EL, Kuukasjarvi T, Karhu R and Kallioniemi A: A comprehensive expression survey of bone morphogenetic proteins in breast cancer highlights the importance of BMP4 and BMP7. Breast Cancer Res Treat 103: 239-246, 2007. (Pubitemid 46789146)
25. Alarmo EL, Korhonen T, Kuukasjarvi T, Huhtala H, Holli K and Kallioniemi A: Bone morphogenetic protein 7 expression associates with bone metastasis in breast carcinomas. Ann Oncol 19: 308-314, 2008. (Pubitemid 351201712)
26. Katsuno Y, Hanyu A, Kanda H, Ishikawa Y, Akiyama F, Iwase T, Ogata E, Ehata S, Miyazono K and Imamura T: Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway. Oncogene 27: 6322-6333, 2008.
27. Babitt JL, Zhang Y, Samad TA, Xia Y, Tang J, Campagna JA, Schneyer AL, Woolf CJ and Lin HY: Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor. J Biol Chem 280: 29820-29827, 2005. (Pubitemid 41177060)
28. Xia Y, Yu PB, Sidis Y, Beppu H, Bloch KD, Schneyer AL and Lin HY: Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4. J Biol Chem 282: 18129-18140, 2007. (Pubitemid 47100254)
29. Conrad S, Genth H, Hofmann F, Just I and Skutella T: Neogenin-RGMa signaling at the growth cone is bone morphogenetic protein-independent and involves RhoA, ROCK, and PKC. J Biol Chem 282: 16423-16433, 2007. (Pubitemid 47100392)
30. Lee DH, Zhou LJ, Zhou Z, Xie JX, Jung JU, Liu Y, Xi CX, Mei L and Xiong WC: Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis. Blood 115: 3136-3145, 2010.