Clinical efficacy of blue light full body irradiation as treatment option for severe atopic dermatitis

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Becker, Detlef ^a   Langer, Elise ^a   Seemann, Martin ^a   Seemann, Gunda ^a   Fell, Isabel ^a   Saloga, Joachim ^a   Grabbe, Stephan ^a   von Stebut, Esther ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CORTICOSTEROID; HLA DR ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 5; T6 ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ANTIGEN PRESENTING CELL; ARTICLE; ATOPIC DERMATITIS; BLUE LIGHT WHOLE BODY RADIATION; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE CONTROL; DISEASE EXACERBATION; DISEASE SEVERITY; ECZEMA AREA AND SEVERITY INDEX; FEMALE; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; INTERMETHOD COMPARISON; LANGERHANS CELL; MALE; MEDICAL DECISION MAKING; MEDICAL RESEARCH; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; QUALITY OF LIFE; SKIN BIOPSY; SKIN PRURITUS; SLEEP; T CELL DEPLETION; TREATMENT DURATION; TREATMENT OUTCOME; ULTRAVIOLET RADIATION; WHOLE BODY RADIATION; CHRONIC DISEASE; CLINICAL TRIAL; COLOR; IMMUNOLOGY; LIGHT; METHODOLOGY; MIDDLE AGED; PATHOLOGY; PATIENT SATISFACTION; SEROLOGY;

ADULT; CHRONIC DISEASE; COLOR; DERMATITIS, ATOPIC; FEMALE; HUMANS; LIGHT; MALE; MIDDLE AGED; PATIENT SATISFACTION; QUALITY OF LIFE; SEROLOGIC TESTS; TREATMENT OUTCOME; WHOLE-BODY IRRADIATION; YOUNG ADULT;

EID: 79958162253     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020566     Document Type: Article

References (19)

1. Boguniewicz M, Leung DY, (2010) Recent insights into atopic dermatitis and implications for management of infectious complications. J Allergy Clin Immunol 125: 4-15.
2. Hoare C, Li W, Williams H, (2000) Systematic review of treatments of atopic eczema. In: Health Technology Assessment 4: 1-191.
3. Werfel T, Claes C, Kulp W, Greiner W, Graf von der Schulenburg JM, (2006) Therapie der Neurodermitis. In: Health Technology Assessment 4: 1-176.
4. Werfel T, Aberer W, Augustin M, Biedermann T, Fölster-Holst R, et al. (2009) Atopic dermatitis: S2 guidelines. J Dtsch Dermatol Ges 7: S1-46.
5. Krutmann J, Medve-Koenigs K, Ruzicka T, Ranft U, Wilkens JH, (2005) Ultraviolet-free phototherapy. Photodermatol Photoimmunol Photomed 21: 59-61.
6. Diepgen TL, Fartasch M, Hornstein OP, (1989) Evaluation and relevance of atopic basic and minor features in patients with atopic dermatitis and in the general population. Acta Derm Venereol Suppl (Stockh) 144: 50-4.
7. Hanifin JM, Thurston M, Omoto M, Cherill R, Tofte SJ, et al. (2001) The eczema area and severity index (EASI): assessment of reliability in atopic dermatitis. EASI Evaluator Group. Exp Dermatol 10: 11-8.
8. Finlay AY, Khan GK, (1994) Dermatology Life Quality Index (DLQI) - a simple practical measure for routine clinical use. Clin Exp Dermatol 19: 210-16.
9. Schwarz T, (2008) 25 years of UV-induced immunosuppression mediated by T cells-from disregarded T suppressor cells to highly respected regulatory T cells. Photochem Photobiol 84: 10-8.
10. Meduri NB, Vandergriff T, Rasmussen H, Jacobe H, (2007) Phototherapy in the management of atopic dermatitis: a systematic review. Photodermatol Photoimmunol Photomed 23: 106-12.
11. von Kobyletzki G, Pieck C, Hoffmann K, Freitag M, Altmeyer P, (1999) Medium-dose UVA1 cold-light phototherapy in the treatment of severe atopic dermatitis. J Am Acad Dermatol 41: 931-7.
12. Polderman MC, Wintzen M, le Cessie S, Pavel S, (2005) UVA-1 cold light therapy in the treatment of atopic dermatitis: 61 patients treated in the Leiden University Medical Center". Photodermatol Photoimmunol Photomed 21: 93-6.
13. Der Petrossian M, Seeber, A, Hoe H, Nigsmann H, Tanew A, (2000) Half-side comparison study on the efficacy of 8-methoxypsoralen bath-PUVA versus narrow-band ultraviolet B phototherapy in patients with severe chronic atopic dermatitis. Br J Dermatol 142: 39-43.
14. Greinert R, (2009) Skin cancer: new markers for better prevention. Pathobiology 76: 64-81.
15. Saeki H, Tamaki K, (2006) Thymus and activation regulated chemokine (TARC)/CCL17 and skin diseases. J Dermatol Sci 43: 75-84.
16. Kleinpenning MM, Smits T, Frunt MH, van Erp PE, van de Kerkhof PC, et al. (2010) Clinical and histological effects of blue light on normal skin. Photodermatol Photoimmunol Photomed 26: 16-21.
17. Grundmann SA, Beissert S, (2009) Regulation of cellular immunity by Photo(chemo)therapy. Front Biosci 14: 4326-36.
18. Loser K, Beissert S, (2009) Regulation of cutaneous immunity by the environment: an important role for UV irradiation and vitamin D. Int Immunopharmacol 9: 587-9.
19. Weichenthal M, Schwarz T, (2005) Phototherapy: how does UV work? Photodermatol Photoimmunol Photomed 21: 260-6.