Effects of anti-factor VIII inhibitor antibodies on factor VIIa/tissue factor-catalysed activation and inactivation of factor VIII

Thrombosis and Haemostasis

Volumn 105, Issue 6, 2011, Pages 989-998

  Yada, Koji ^a   Nogami, Keiji ^a   Ogiwara, Kenichi ^a   Shibata, Masaru ^a   Shima, Midori ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

Activation inactivation; Cleavage; FVIIa TF; FVIII; FVIII inhibitor antibodies

Indexed keywords

ARGININE; AUTOANTIBODY; BLOOD CLOTTING FACTOR 7A; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 8 ANTIBODY; BLOOD CLOTTING FACTOR 8 INHIBITOR; COMPLEMENT COMPONENT C2; POLYCLONAL ANTIBODY; THROMBOPLASTIN;

ALLOIMMUNITY; ANTIBODY SPECIFICITY; ANTIBODY TITER; ANTICOAGULATION; ANTIGEN ANTIBODY REACTION; ARTICLE; BLOOD CLOTTING; CATALYSIS; CONTROLLED STUDY; EPITOPE MAPPING; HEMOSTASIS; HUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN DOMAIN; WESTERN BLOTTING;

ANTIBODIES, BLOCKING; ARGININE; BLOOD COAGULATION; CATALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITOPES; FACTOR VIIA; FACTOR VIII; HUMANS; HYDROLYSIS; PROTEIN BINDING; SUBSTRATE SPECIFICITY; THROMBIN; THROMBOPLASTIN;

EID: 79958153738     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH10-12-0781     Document Type: Article

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