Identification of a plasmin-interactive site within the A2 domain of the factor VIII heavy chain

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1784, Issue 5, 2008, Pages 753-763

  Nogami, Keiji ^a   Nishiya, Katsumi ^a   Saenko, Evgueni L ^b   Takeyama, Masahiro ^a   Tanaka, Ichiro ^a   Yoshioka, Akira ^a   Shima, Midori ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

A2 domain; A2 mutant; Factor VIII; Inactivation; Interactive site; Plasmin

Indexed keywords

ALANINE; ARGININE; BLOOD CLOTTING FACTOR 8; MONOCLONAL ANTIBODY; PEPTIDE; PLASMIN;

ARTICLE; BINDING AFFINITY; BINDING SITE; BLOOD CLOT; CONTROLLED STUDY; ENZYME DEGRADATION; ENZYME INACTIVATION; ENZYME INHIBITION; HUMAN; MOLECULE; MUTANT; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; WILD TYPE;

6-AMINOCAPROIC ACID; ANTIBODIES; BINDING SITES; CATALYSIS; FACTOR IXA; FACTOR VIII; HUMANS; KINETICS; MUTANT PROTEINS; PEPTIDES; PLASMIN; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; SURFACE PLASMON RESONANCE;

EID: 41949109750     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2008.01.019     Document Type: Article

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