Antioxidant activity of Citrus limon essential oil in mouse hippocampus

Pharmaceutical Biology

Volumn 49, Issue 7, 2011, Pages 709-715

  Lopes Campělo, Lidianne Mayra ^a   Moura Gonçcalves, Fabrício Custódio ^a   Feitosa, Chistiane Mendes ^a   De Freitas, Rivelilson Mendes ^a  

^a FEDERAL UNIVERSITY OF PIAUÍ   (Brazil)

Author keywords

Citrus limon; essential oil; hippocampus; mice; oxidative stress

Indexed keywords

CATALASE; ESSENTIAL OIL; GLUTATHIONE; GLUTATHIONE PEROXIDASE; NITRITE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN LEVEL; CONTROLLED STUDY; DRUG DETERMINATION; DRUG MECHANISM; ENZYME ACTIVITY; HIPPOCAMPUS; LEMON; LIPID PEROXIDATION; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS;

ANIMALS; ANTIOXIDANTS; CITRUS; DOSE-RESPONSE RELATIONSHIP, DRUG; HIPPOCAMPUS; LIPID PEROXIDATION; MALE; MEDICINE, TRADITIONAL; MICE; NEURODEGENERATIVE DISEASES; OILS, VOLATILE; OXIDATIVE STRESS; SPECTROPHOTOMETRY;

CITRUS LIMON; MUS; RUTACEAE;

EID: 79958149470     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2010.541924     Document Type: Article

References (46)

1. Akbas SH, Yegin A, Ozben T. (2005). Effect of pentylenetetrazolinduced epileptic seizure on the antioxidant enzyme activities, glutathione and lipid peroxidation levels in rat erythrocytes and liver tissues. Clin Biochem 38:1009-1014. (Pubitemid 41613686)
2. Barros DO, Xavier SM, Barbosa CO, Silva RF, Freitas RL, Maia FD, Oliveira AA, Freitas RM, Takahashi RN. (2007). Effects of the vitamin E in catalase activities in hippocampus after status epilepticus induced by pilocarpine in Wistar rats. Neurosci Lett 416:227-230. (Pubitemid 46509481)
3. Benavente-Garcia O, Castillo J, Marin FR, Ortuno A, Del Rio JA. (1997). Uses and properties of citrus flavonoids. J Agric Food Chem 45:4505-4515.
4. Castagne V, Gautschi M, Lefevre K, Posada A, Clarke PG. (1999). Relationships between neuronal death and the cellular redox status. Focus on the developing nervous system. Prog Neurobiol 59:397-423. (Pubitemid 29352342)
5. Chance B, Maehly AC. (1955). Assay of catalases and peroxidases. Methods Enzymol 2:764-775.
6. De Sousa DP, Quintans JL, Almeida RN. (2007). Evaluation of the anticonvulsant activity of α-terpineol. Pharm Biol 45:69-70.
7. Del Río JA, Arcas MC, Benavente-García O, Ortuño A. (1998). Citrus polymethoxylated flavones can confer resistance against Phytophthora citrophthora, Penicillium digitatum, and Geotrichum species. J Agric Food Chem 46:4423-4428. (Pubitemid 128488555)
8. Draper HH, Hadley M. (1990). Malondialdehyde determination as index of lipid peroxidation. Meth Enzymol 186:421-431. (Pubitemid 20279983)
9. Dymond AM, Crandall PH. (1976). Oxygen availability and blood flow in the temporal lobes during spontaneous epileptic seizures in man. Brain Res 102:191-196.
10. Elangovan V, Sekar N, Govindasamy S. (1994). Chemopreventive potential of dietary bioflavonoids against 20-methylcholanthreneinduced tumorigenesis. Cancer Lett 87:107-113. (Pubitemid 24352947)
11. Ferreira PM, Militão GC, Freitas RM. (2009). Lipoic acid effects on lipid peroxidation level, superoxide dismutase activity and monoamines concentration in rat hippocampus. Neurosci Lett 464:131-134.
12. Flohé L, Otting F. (1984). Superoxide dismutase assays. Meth Enzymol 105:93-104. (Pubitemid 14165376)
13. Freitas RM. (2009). The evaluation of effects of lipoic acid on the lipid peroxidation, nitrite formation and antioxidant enzymes in the hippocampus of rats after pilocarpine-induced seizures. Neurosci Lett 455:140-144.
14. Freitas RM, Bezerra Felipe C F, Nascimento VS, Oliveira AA, Viana GS, Fonteles MM. (2003). Pilocarpine-induced seizures in adult rats: monoamine content and muscarinic and dopaminergic receptor changes in the striatum. Comp Biochem Physiol C Toxicol Pharmacol 136:103-108. (Pubitemid 37237544)
15. Freitas RM, Vasconcelos SM, Souza FC, Viana GS, Fonteles MM. (2005). Oxidative stress in the hippocampus after pilocarpineinduced status epilepticus in Wistar rats. FEBS J 272:1307-1312. (Pubitemid 40444922)
16. Gottlieb M, Leal-Campanario R, Campos-Esparza MR, Sánchez- Gómez MV, Alberdi E, Arranz A, Delgado-García JM, Gruart A, Matute C. (2006). Neuroprotection by two polyphenols following excitotoxicity and experimental ischemia. Neurobiol Dis 23:374-386. (Pubitemid 44080844)
17. Green LC, Tannenbaum SR, Goldman P. (1981). Nitrate synthesis in the germfree and conventional rat. Science 212:56-58. (Pubitemid 11114678)
18. Halliwell B, Gutteridge JMC. (1999). Free Radical in Biology and Medicine, 3rd edition. London: Oxford Science Publications, pp. 935-938.
19. Halliwell B, Gutteridge JMC. (1989). Lipid peroxidation: A radical chain reaction. Free Radical in Biology and Medicine, 2nd edition. Oxford: Clarendon Press, pp. 188-276.
20. Hsieh CL, Tang NY, Chiang SY, Hsieh CT, Lin JG. (1999). Anticonvulsive and free radical scavenging actions of two herbs, Uncaria rhynchophylla (MIQ) Jack and Gastrodia elata Bl., in kainic acidtreated rats. Life Sci 65:2071-2082.
21. Kudin AP, Bimpong-Buta NY, Vielhaber S, Elger CE, Kunz WS. (2004). Characterization of superoxide-producing sites in isolated brain mitochondria. J Biol Chem 279:4127-4135. (Pubitemid 38198997)
22. Liang LP, Beaudoin ME, Fritz MJ, Fulton R, Patel M. (2007). Kainateinduced seizures, oxidative stress and neuronal loss in aging rats. Neuroscience 147:1114-1118. (Pubitemid 47102535)
23. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. (1951). Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275.
24. Maehly AC, Chance B. (1954). The assay of catalases and peroxidases. Methods Biochem Anal 1:357-424.
25. Matos FJA, Machado MIL, Craveiro AA, Alencar JW. (1996). Essential oil composition of two chemotypes of Lippia alba grown in northeast Brazil. J Essent Oil Res 8:695-698. (Pubitemid 126478682)
26. McCord JM. (1995). Superoxide radical: controversies, contradictions, and paradoxes. Proc Soc Exp Biol Med 209:112-117.
27. Michiels C, Raes M, Toussaint O, Remacle J. (1994). Importance of Se-glutathione peroxidase, catalase, and Cu/Zn-SOD for cell survival against oxidative stress. Free Radic Biol Med 17:235-248.
28. Militão GC, Ferreira PM, de Freitas RM. (2010). Effects of lipoic acid on oxidative stress in rat striatum after pilocarpine-induced seizures. Neurochem Int 56:16-20.
29. Miyake Y, Yamamoto K, Morimitsu Y, Osawa T. (1998). Characteristics of antioxidative flavonoid glycosides in lemon fruit. Food Sci Technol Int 4:48-53.
30. Miyake Y, Yamamoto K, Morimitsu Y, Osawa T. (1997). Isolation of C-glucosylflavone from lemon peel and antioxidative activity of flavonoid compounds in lemon fruit. J Agric Food Chem 45:4619-4623. (Pubitemid 127485814)
31. Monforte MT, Trovato A, Kirjavainen S, Forestieri AM, Galati EM, Lo Curto RB. (1995). Biological effects of hesperidin, a citrus flavonoid (note II): Hypolipidemic activity on experimental hypercholesterolemia in rat. Farmaco 50:595-599.
32. Obay BD, Tasdemir E, Tümer C, Bilgin HM, Atmaca M. (2008). Dose dependent effects of ghrelin on pentylenetetrazole-induced oxidative stress in a rat seizure model. Peptides 29:448-455.
33. Oliveira AA, Almeida JP, Freitas RM, Nascimento VS, Aguiar LM, Júnior HV, Fonseca FN, Viana GS, Sousa FC, Fonteles MM. (2007). Effects of levetiracetam in lipid peroxidation level, nitrite-nitrate formation and antioxidant enzymatic activity in mice brain after pilocarpine-induced seizures. Cell Mol Neurobiol 27:395-406. (Pubitemid 46763886)
34. Ono H, Sakamoto A, Sakura N. (2000). Plasma total glutathione concentrations in epileptic patients taking anticonvulsants. Clin Chim Acta 298:135-143. (Pubitemid 30392461)
35. Ortuño A, Reynaldo I, Fuster MD, Botía J, Puig DG, Sabater F, Lidón AG, Porras I, Del Río JA. (1997). Citrus cultivars with high flavonoid contents in the fruits. Sci Hortic 68:231-236. (Pubitemid 27165167)
36. Rice-Evans C, Miller N, Paganga G. (1997). Antioxidant properties of phenolic compounds. Trends Plant Sci 2:152-159. (Pubitemid 27158898)
37. Santos IM, Tomé Ada R, Feitosa CM, de Souza GF, Feng D, de Freitas RM, Jordán J. (2010). Lipoic acid blocks seizures induced by pilocarpine via increases in delta-aminolevulinic dehydratase and Na+, K+-ATPase activity in rat brain. Pharmacol Biochem Behav 95:88-91.
38. Santos LF, Freitas RL, Xavier SM, Saldanha GB, Freitas RM. (2008). Neuroprotective actions of vitamin C related to decreased lipid peroxidation and increased catalase activity in adult rats after pilocarpine-induced seizures. Pharmacol Biochem Behav 89:1-5.
39. Sedlak J, Lindsay RH. (1968). Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent. Anal Biochem 25:192-205.
40. Sharma AB, Sun J, Howard LL, Williams AG Jr, Mallet RT. (2007). Oxidative stress reversibly inactivates myocardial enzymes during cardiac arrest. Am J Physiol Heart Circ Physiol 292: H198-H206. (Pubitemid 46105179)
41. Sinet PM, Michelson AM, Bazin A, Lejeune J, Jerome H. (1975). Increase in glutathione peroxidase activity in erythrocytes from trisomy 21 subjects. Biochem Biophys Res Commun 67:910-915.
42. Tanaka T, Makita H, Kawabata K, Mori H. (1996). Chemoprotection of 4-NOO-induced oral carcinogenesis by dietary flavonoids diosmin and hesperidin. Rec Adv Gastroenterol Carcinogen 1:1167-1170.
43. Viana GS, do Vale TG, Silva CM, Matos FJ. (2000). Anticonvulsant activity of essential oils and active principles from chemotypes of Lippia alba (Mill.) N. E. Brown. Biol Pharm Bull 23:1314-1317.
44. Vinson JA, Proch J, Bose P. (2001). Determination of quantity and quality of polyphenol antioxidants in foods and beverages. Meth Enzymol 335:103-114. (Pubitemid 32507230)
45. Walz R, Dal-Pizzol F, Klamt F, Vianna MMR, Schröder N, Quevedo J, Benfato MS, Moreira JCF. (2000). Lipid peroxidation in hippocampus early and late after status epilepticus induced by pilocarpine or kainic acid in Wistar rats. Neurosci Lett 291:179-182. (Pubitemid 30657921)
46. Xavier SM, Barbosa CO, Barros DO, Silva RF, Oliveira AA, Freitas RM. (2007). Vitamin C antioxidant effects in hippocampus of adult Wistar rats after seizures and status epilepticus induced by pilocarpine. Neurosci Lett 420:76-79. (Pubitemid 46783964)