A novel method for assessing adherent single-cell stiffness in tension: Design and testing of a substrate-based live cell functional imaging device

Biomedical Microdevices

Volumn 13, Issue 2, 2011, Pages 291-301

  Bartalena, Guido ^a,b   Grieder, Reto ^a   Sharma, Ram I ^a,b   Zambelli, Tomaso ^b   Muff, Roman ^a   Snedeker, Jess G ^a,b  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b ETH ZURICH   (Switzerland)

Author keywords

Biaxial stretching; Cell mechanics; Experiments; Feature tracking; Modeling; Single live cell imaging

Indexed keywords

ANALYSIS APPROACH; BIAXIAL STRETCHING; CELL CYTOSKELETON; CELL MECHANICS; CELL STIFFNESS; CELL SUBSTRATES; CELL-SUBSTRATE INTERACTIONS; CHEMICAL TREATMENTS; CONSTITUTIVE PROPERTIES; CULTURE SYSTEMS; DIGITAL IMAGE CORRELATIONS; DYNAMIC ADJUSTMENT; FEATURE-TRACKING; FUNCTIONAL IMAGING; GLUTARALDEHYDES; LIVE CELL; LIVE-CELL IMAGING; LIVING CELL; MAGNIFICATION IMAGES; MICRO DEVICES; MICROBEADS; NANOINDENTATION TESTING; NOVEL METHODS; OSTEOSARCOMA CELLS; PARAMETRIC FINITE ELEMENTS; POLYDIMETHYLSILOXANE PDMS; REAL-TIME TRACKING SYSTEMS; SINGLE CELLS; SUBSTRATE DEFORMATION; TARGET-SUBSTRATE;

ADHESION; ALDEHYDES; BIOMECHANICS; CELL ADHESION; CELLS; DEFORMATION; FINITE ELEMENT METHOD; IMAGE ANALYSIS; IODINE; NANOINDENTATION; SILICONES; STIFFNESS; SUBSTRATES;

CELL CULTURE;

COLLAGEN TYPE 1; CYTOCHALASIN D; DIMETICONE; GLUTARALDEHYDE;

ARTICLE; ATOMIC FORCE MICROSCOPY; CALIBRATION; CELL ADHESION; CELL CULTURE; CELL TRACKING; CONTROLLED STUDY; CYTOSKELETON; EQUIPMENT DESIGN; FINITE ELEMENT ANALYSIS; GEOMETRY; HUMAN; HUMAN CELL; IMAGE ANALYSIS; IMAGE PROCESSING; MATERIAL COATING; MECHANICS; NANOFABRICATION; OSTEOSARCOMA CELL; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS; SINGLE CELL ANALYSIS; TENSILE STRENGTH;

BIOMECHANICS; CALIBRATION; CELL ADHESION; CELL CULTURE TECHNIQUES; CELL LINE; CELL SURVIVAL; CELL TRACKING; DIMETHYLPOLYSILOXANES; EQUIPMENT DESIGN; FINITE ELEMENT ANALYSIS; HUMANS; MECHANICAL PROCESSES; MICROSCOPY, ATOMIC FORCE; MOLECULAR IMAGING;

EID: 79958149401     PISSN: 13872176     EISSN: 15728781     Source Type: Journal    
DOI: 10.1007/s10544-010-9493-3     Document Type: Article

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