Copolymer-based hepatocyte asialoglycoprotein receptor targeting agent for SPECT

Journal of Nuclear Medicine

Volumn 52, Issue 6, 2011, Pages 978-985

  Yang, Wenjiang ^a   Mou, Tiantian ^a   Shao, Guoqiang ^b   Wang, Feng ^b   Zhang, Xianzhong ^a   Liu, Boli ^a  

^a BEIJING NORMAL UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

99mTc; Animal imaging; Asialoglycoprotein receptor; P(VLA co VNI); Radiopharmaceuticals

Indexed keywords

ASIALOGLYCOPROTEIN RECEPTOR; COPOLYMER; POLY[N 4 VINYLBENZYL (O BETA DEXTRO GALACTOPYRANOSYL(1-4) DEXTRO GLUCONAMIDE) CO N 4 VINYLBENZYL 6 [2 (4 DIMETHYLAMINO)BENZALDEHYDEHYDRAZONO]NICOTINATE](2 TRICINE) TC 99M; POLYSTYRENE DERIVATIVE; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; FEMALE; IMAGE ANALYSIS; IN VIVO STUDY; ISOTOPE LABELING; LIVER CELL; MOUSE; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; RABBIT; RADIATION DETECTION; RADIOACTIVITY; RADIOCHEMISTRY; RECEPTOR BINDING; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

ANIMALS; ASIALOGLYCOPROTEIN RECEPTOR; CARRIER PROTEINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, THIN LAYER; GALACTOSE; HEPATOCYTES; HYDRAZINES; IODINE RADIOISOTOPES; LACTOSE; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MEMBRANE PROTEINS; MICE; NIACINAMIDE; POLYSTYRENES; SPECTROPHOTOMETRY, INFRARED; TECHNETIUM; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 79958139975     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.110.085167     Document Type: Article

References (32)

1. Kokudo N, Vera DR, Makuuchi M. Clinical application of TcGSA. Nucl Med Biol. 2003;30:845-849. (Pubitemid 38040993)
2. Stadalnik RC, Vera DR. The evolution of 99mTc-NGA as a clinically useful receptor-binding radiopharmaceutical. Nucl Med Biol. 2001;28:499-503. (Pubitemid 32539398)
3. Saha GB. Fundamentals of Nuclear Pharmacy. 4th ed. New York, NY: Springer New York; 1998.
4. Kim EM, Jeong HJ, Kim SL, et al. Asialoglycoprotein-receptor-targeted hepatocyte imaging using Tc-99m galactosylated chitosan. Nucl Med Biol. 2006;33:529-534.
5. de Graaf W, Bennink RJ, Vetelainen R, van Gulik TM. Nuclear imaging techniques for the assessment of hepatic function in liver surgery and transplantation. J Nucl Med. 2010;51:742-752.
6. Vera DR, Stadalnik RC, Krohn KA. Technetium-99m galactosyl- neoglycoalbumin: preparation and preclinical studies. J Nucl Med. 1985;26:1157-1167.
7. Kubota Y, Kojima M, Hazama H, et al. A new liver function test using the asialoglycoprotein-receptor system on the liver cell membrane: I. Evaluation of liver imaging using Tc-99m-neoglycoprotein [in Japanese]. Kaka Igaku. 1986;23:899-905.
8. Ono M, Arano Y, Uehara T, et al. Intracellular metabolic fate of radioactivity after injection of technetium-99m-labeled hydrazino nicotinamide derivatized proteins. Bioconjug Chem. 1999;10:386-394. (Pubitemid 29243319)
9. 99mTc-DMP-NGA as a novel hepatic asialoglycoprotein receptor imaging agent. Appl Radiat Isot. 2010;68:105-109.
10. 99mTc chelating albumin for measurement of liver function. Bioconjug Chem. 2010;21:589-596.
11. Jeong JM, Hong MK, Lee J, et al. Tc-99m-neolactosylated human serum albumin for imaging the hepatic asialoglycoprotein receptor. Bioconjug Chem. 2004;15:850-855. (Pubitemid 38981960)
12. Wakisaka K, Arano Y, Uezono T, et al. A novel radioiodination reagent for protein radiopharmaceuticals with L-lysine as a plasma-stable metabolizable linkage to liberate m-iodohippuric acid after lysosomal proteolysis. J Med Chem. 1997;40:2643-2652. (Pubitemid 27347029)
13. Arano Y, Mukai T, Akizawa H, et al. Radiolabeled metabolites of proteins play a critical role in radioactivity elimination from the liver. Nucl Med Biol. 1995;22:555-564.
14. Vera DR. Gallium-labeled deferoxamine-galactosyl-neoglycoalbumin: a radiopharmaceutical for regional measurement of hepatic receptor biochemistry. J Nucl Med. 1992;33:1160-1166.
15. Yang W, Mou T, Peng C, et al. Fluorine-18 labeled galactosyl- neoglycoalbumin for imaging the hepatic asialoglycoprotein receptor. Bioorg Med Chem. 2009;17:7510-7516.
16. Park I-K, Yang J, Jeong H-J, et al. Galactosylated chitosan as a synthetic extracellular matrix for hepatocytes attachment. Biomaterials. 2003;24:2331-2337. (Pubitemid 36434053)
17. Vera DR, Hall DJ, Hoh CK, Gallant P, McIntosh LM, Mattrey RF. Cy5.5-DTPA-galactosyl-dextran: a fluorescent probe for in vivo measurement of receptor biochemistry. Nucl Med Biol. 2005;32:687-693. (Pubitemid 41502973)
18. Kim EM, Jeong HJ, Park IK, Cho CS, Kim CG, Bom HS. Hepatocyte-targeted nuclear imaging using Tc-99m-galactosylated chitosan: conjugation, targeting, and biodistribution. J Nucl Med. 2005;46:141-145.
19. Yang W, Mou T, Guo W, et al. Fluorine-18 labeled galactosylated chitosan for asialoglycoprotein-receptor-mediated hepatocyte imaging. Bioorg Med Chem Lett. 2010;20:4840-4844.
20. Hiratsuka T, Goto M, Kondo Y, Cho CS, Akaike TR. Copolymers for hepatocyte-specific targeting carrying galactose and hydrophobic alkyl groups. Macromol Biosci. 2008;8:231-238.
21. 125I-labelled lactose-carrying polystyrene. J Control Release. 1994;28:223-233.
22. Kobayashi K, Sumitomo H, Ina YA. Carbohydrate-containing synthetic polymer obtained from N-p-vinylbenzyl-D-gluconamide. Polym J. 1983;15:667-671. (Pubitemid 14503391)
23. Kobayashi K, Sumitomo H, Ina Y. Synthesis and functions of polystyrene derivatives having pendant oligosaccharides. Polym J. 1985;17:567-575. (Pubitemid 15509342)
24. 99mTc-labeled radiopharmaceuticals. Bioconjug Chem. 1999;10:808-814.
25. Clavien PA, Petrowsky H, DeOliveira ML, Graf R. Strategies for safer liver surgery and partial liver transplantation. N Engl J Med. 2007;356:1545-1559. (Pubitemid 46588419)
26. Stockert RJ. The asialoglycoprotein receptor: relationships between structure, function, and expression. Physiol Rev. 1995;75:591-609.
27. 99mTc-DTPA-galactosyl-human serum albumin dynamic SPECT. J Nucl Med. 1999;40:1644-1651.
28. 99mTc-GSA SPECT and their usefulness in prognostic estimation after hepatectomy. J Nucl Med. 2000;41:421-425.
29. Shuke N, Okizaki A, Kino S, et al. Functional mapping of regional liver asialoglycoprotein receptor amount from single blood sample and SPECT. J Nucl Med. 2003;44:475-482. (Pubitemid 39586027)
30. 99mTc-labeling of small biomolecules. In: Topics in Current Chemistry, Contrast Agents III. Heidelberg, Germany: Springer Berlin; 2005:117-153.
31. Duncan JR, Welch MJ. Intracellular metabolism of indium-111-DTPA-labeled receptor targeted proteins. J Nucl Med. 1993;34:1728-1738. (Pubitemid 23295386)
32. Arano Y, Mukai T, Uezono T, et al. A biological method to evaluate bifunctional chelating agents to label antibodies with metallic radionuclides. J Nucl Med. 1994;35:890-898. (Pubitemid 24151231)