Copy number loss of (src homology 2 domain containing)-transforming protein 2 (SHC2) gene: Discordant loss in monozygotic twins and frequent loss in patients with multiple system atrophy

Molecular Brain

Volumn 4, Issue 1, 2011, Pages

  Sasaki, Hidenao ^a   Emi, Mitsuru ^b   Iijima, Hiroshi ^b   Ito, Noriko ^b   Sato, Hidenori ^b   Yabe, Ichiro ^a   Kato, Takeo ^c   Utsumi, Jun ^d,e   Matsubara, Kenichi ^b  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b DNA CHIP RESEARCH INC   (Japan)

^c YAMAGATA UNIVERSITY   (Japan)

^d HOKKAIDO UNIVERSITY   (Japan)

^e KYOTO UNIVERSITY   (Japan)

Author keywords

(Src homology 2 domain containing) transforming protein 2; ataxia; copy number variation; disease susceptibility gene; Multiple system atrophy; parkinsonism; phenotypically discordant monozygotic twins; subtelomere

Indexed keywords

GENOMIC DNA; OLIGONUCLEOTIDE; PROTEIN SHC; SRC HOMOLOGY 2 DOMAIN CONTAINING TRANSFORMING PROTEIN 2; TRANSFORMING PROTEIN; UNCLASSIFIED DRUG; SHC2 PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; CHROMOSOME 19P; CLINICAL ARTICLE; CLINICAL FEATURE; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; COPY NUMBER LOSS; COPY NUMBER VARIATION; CORRELATION ANALYSIS; FEMALE; GENE; GENE DELETION; GENETIC SUSCEPTIBILITY; GENOME ANALYSIS; HETEROZYGOSITY; HUMAN; HUMAN CELL; MALE; MICROARRAY ANALYSIS; MONOZYGOTIC TWINS; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; SHY DRAGER SYNDROME; SRC HOMOLOGY 2 DOMAIN CONTAINING TRANSFORMING PROTEIN 2 GENE; TWIN DISCORDANCE; DNA MICROARRAY; GENE DOSAGE; GENETIC SCREENING; GENETICS; HUMAN GENOME; MIDDLE AGED;

ADULT; AGED; FEMALE; GENE DOSAGE; GENETIC TESTING; GENOME, HUMAN; HUMANS; MALE; MIDDLE AGED; MULTIPLE SYSTEM ATROPHY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; SHC SIGNALING ADAPTOR PROTEINS; TWINS, MONOZYGOTIC;

EID: 79958118184     PISSN: None     EISSN: 17566606     Source Type: Journal    
DOI: 10.1186/1756-6606-4-24     Document Type: Article

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