Microfluidic cell culture chip with multiplexed medium delivery and efficient cell/scaffold loading mechanisms for high-throughput perfusion 3-dimensional cell culture-based assays

Biomedical Microdevices

Volumn 13, Issue 3, 2011, Pages 415-430

  Huang, Song Bin ^a   Wu, Min Hsien ^b   Wang, Shih Siou ^b   Lee, Gwo Bin ^c  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c NATIONAL TSING HUA UNIVERSITY   (Taiwan)

Author keywords

3 D cell culture; Microbioreactors; Microfluidics; Micropumps; Perfusion cell culture

Indexed keywords

3-D CELL CULTURE; 3-DIMENSIONAL; BACKFLOW; HIGH-PRECISION; HIGH-THROUGHPUT; LOW CONSUMPTION; MICRO BIOREACTOR; MICRO PUMP; MICRO-SCALES; MICROBIOREACTORS; MICROFLUIDIC CELL CULTURE; MICROPUMPS; MOLD MACHINING; PERFUSION CELL CULTURE; POLYDIMETHYLSILOXANE PDMS; PUMPING MECHANISM; PUMPING RATE; REPLICATION PROCESS; SIMPLE CELL;

ASSAYS; BIOREACTORS; CELLS; LOADING; MACHINING; MICROCHANNELS; MICROFLUIDICS; MULTIPLEXING; PUMPS; SCAFFOLDS (BIOLOGY); SILICONES; THREE DIMENSIONAL; THROUGHPUT;

CELL CULTURE;

AGAROSE; DIMETICONE; POLY(METHYL METHACRYLATE);

ARTICLE; AUTOMATION; BIOCHIP; BIOREACTOR; CARTILAGE CELL; CELL VIABILITY; CULTURE MEDIUM; MICROENVIRONMENT; MICROFLUIDIC CELL CULTURE CHIP; MICROFLUIDICS; PNEUMATIC TOOL; PRIORITY JOURNAL; THREE DIMENSIONAL IMAGING;

ANIMALS; CELL CULTURE TECHNIQUES; CHONDROCYTES; CULTURE MEDIA; EXTRACELLULAR SPACE; HYDROGEN-ION CONCENTRATION; MICROFLUIDIC ANALYTICAL TECHNIQUES; PERFUSION; SEPHAROSE; TISSUE SCAFFOLDS;

EID: 79958098032     PISSN: 13872176     EISSN: 15728781     Source Type: Journal    
DOI: 10.1007/s10544-011-9510-1     Document Type: Article

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