Abrogation of nimesulide induced oxidative stress and mitochondria mediated apoptosis by Fumaria parviflora Lam. extract

Journal of Ethnopharmacology

Volumn 136, Issue 1, 2011, Pages 94-102

  Tripathi, Madhulika ^a,b   Singh, Brijesh Kumar ^a   Raisuddin, Sheikh ^b   Kakkar, Poonam ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

^b HAMDARD UNIVERSITY   (India)

Author keywords

Apoptosis; Fumaria parviflora Lam.; Mitochondria; Nimesulide; Reactive oxygen species

Indexed keywords

CASPASE 3; CASPASE 9; CELL MARKER; CYTOCHROME C; FUMARIA PARVIFLORA EXTRACT; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; LIPOXYGENASE; MESSENGER RNA; NIMESULIDE; PHOSPHATIDYLSERINE; PLANT EXTRACT; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SILYMARIN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CHEMICAL ANALYSIS; CONTROLLED STUDY; DISEASE MARKER; DNA DAMAGE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME RELEASE; FLOW CYTOMETRY; FUMARIA PARVIFLORA; GENE EXPRESSION; HISTOPATHOLOGY; IN VIVO STUDY; LIPID PEROXIDATION; LIVER INJURY; LIVER MITOCHONDRION; LIVER PROTECTION; LIVER TOXICITY; MALE; MEDICINAL PLANT; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OXIDATIVE STRESS; PROTEIN LOCALIZATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; DRUG-INDUCED LIVER INJURY; FUMARIA; LIPID PEROXIDATION; MALE; MITOCHONDRIA; OXIDATIVE STRESS; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SULFONAMIDES;

FUMARIA PARVIFLORA; RATTUS; RATTUS NORVEGICUS;

EID: 79958096956     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.04.014     Document Type: Article

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