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Volumn 18, Issue 7, 2011, Pages 926-932

A novel human volunteer pain model using contact heat evoked potentials (CHEP) following topical skin application of transient receptor potential agonists capsaicin, menthol and cinnamaldehyde

Author keywords

Capsaicin; CHEP; Cinnamaldehyde; Menthol; Topical; TRP

Indexed keywords

CAPSAICIN; CINNAMALDEHYDE; MENTHOL;

EID: 79958086584     PISSN: 09675868     EISSN: 15322653     Source Type: Journal    
DOI: 10.1016/j.jocn.2010.11.015     Document Type: Article
Times cited : (44)

References (59)
  • 1
    • 19444384710 scopus 로고    scopus 로고
    • Human surrogate models of neuropathic pain
    • DOI 10.1016/j.pain.2005.03.021, PII S030439590500117X
    • Klein T, Magerl W, Rolke R, et al. Human surrogate models of neuropathic pain. Pain 2005;115:227-33. (Pubitemid 40725278)
    • (2005) Pain , vol.115 , Issue.3 , pp. 227-233
    • Klein, T.1    Magerl, W.2    Rolke, R.3    Treede, R.-D.4
  • 2
    • 0026534771 scopus 로고
    • Central changes in processing of mechanoreceptive input in capsaicin-induced secondary hyperalgesia in humans
    • Torebjork HE, Lundberg LE, LaMotte RH. Central changes in processing of mechanoreceptive input in capsaicin-induced secondary hyperalgesia in humans. J Physiol 1992;448:765-80.
    • (1992) J Physiol , vol.448 , pp. 765-780
    • Torebjork, H.E.1    Lundberg, L.E.2    LaMotte, R.H.3
  • 3
    • 0035689007 scopus 로고    scopus 로고
    • Characterization of secondary hyperalgesia produced by topical capsaicin jelly - A new experimental tool for pain research
    • DOI 10.1053/eujp.2001.0253
    • Harding LM, Murphy A, Kinnman E, et al. Characterization of secondary hyperalgesia produced by topical capsaicin jelly - a new experimental tool for pain research. Eur J Pain 2001;5:363-71. (Pubitemid 34072463)
    • (2001) European Journal of Pain , vol.5 , Issue.4 , pp. 363-371
    • Harding, L.M.1    Murphy, A.2    Kinnman, E.3    Baranowski, A.P.4
  • 6
    • 34250857978 scopus 로고    scopus 로고
    • Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy
    • Facer P, Casula MA, Smith GD, et al. Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy. BMC Neurol 2007;7:11.
    • (2007) BMC Neurol , vol.7 , pp. 11
    • Facer, P.1    Casula, M.A.2    Smith, G.D.3
  • 7
    • 26444436231 scopus 로고    scopus 로고
    • Increased capsaicin receptor TRPV1 in skin nerve fibres and related vanilloid receptors TRPV3 and TRPV4 in keratinocytes in human breast pain
    • Gopinath P, Wan E, Holdcroft A, et al. Increased capsaicin receptor TRPV1 in skin nerve fibres and related vanilloid receptors TRPV3 and TRPV4 in keratinocytes in human breast pain. BMC Womens Health 2005;5:2.
    • (2005) BMC Womens Health , vol.5 , pp. 2
    • Gopinath, P.1    Wan, E.2    Holdcroft, A.3
  • 12
    • 0037309871 scopus 로고    scopus 로고
    • Sensory fibres expressing capsaicin receptor TRPV1 in patients with rectal hypersensitivity and faecal urgency
    • DOI 10.1016/S0140-6736(03)12392-6
    • Chan CL, Facer P, Davis JB, et al. Sensory fibres expressing capsaicin receptor TRPV1 in patients with rectal hypersensitivity and faecal urgency. Lancet 2003;361:385-91. (Pubitemid 36164972)
    • (2003) Lancet , vol.361 , Issue.9355 , pp. 385-391
    • Chan, C.L.H.1    Facer, P.2    Davis, J.B.3    Smith, G.D.4    Egerton, J.5    Bountra, C.6    Williams, N.S.7    Anand, P.8
  • 13
    • 33646473132 scopus 로고    scopus 로고
    • Psychophysical study of the effects of topical application of menthol in healthy volunteers
    • Hatem S, Attal N, Willer JC, et al. Psychophysical study of the effects of topical application of menthol in healthy volunteers. Pain 2006;122:190-6.
    • (2006) Pain , vol.122 , pp. 190-196
    • Hatem, S.1    Attal, N.2    Willer, J.C.3
  • 14
    • 0029971514 scopus 로고    scopus 로고
    • Effect of topically applied menthol on thermal, pain and itch sensations and biophysical properties of the skin
    • DOI 10.1007/s004030050053
    • Yosipovitch G, Szolar C, Hui XY, et al. Effect of topically applied menthol on thermal, pain and itch sensations and biophysical properties of the skin. Arch Dermatol Res 1996;288:245-8. (Pubitemid 26152058)
    • (1996) Archives of Dermatological Research , vol.288 , Issue.5-6 , pp. 245-248
    • Yosipovitch, G.1    Szolar, C.2    Hui, X.Y.3    Maibach, H.4
  • 15
    • 0026658720 scopus 로고
    • The sensory effects of l-menthol on human skin
    • Green BG. The sensory effects of l-menthol on human skin. Somatosens Mot Res 1992;9:235-44.
    • (1992) Somatosens Mot Res , vol.9 , pp. 235-244
    • Green, B.G.1
  • 16
    • 2442616221 scopus 로고    scopus 로고
    • Topical menthol - A human model for cold pain by activation and sensitization of C nociceptors
    • DOI 10.1093/brain/awh134
    • Wasner G, Schattschneider J, Binder A, et al. Topical menthol - a human model for cold pain by activation and sensitization of C nociceptors. Brain 2004;127:1159-71. (Pubitemid 38623049)
    • (2004) Brain , vol.127 , Issue.5 , pp. 1159-1171
    • Wasner, G.1    Schattschneider, J.2    Binder, A.3    Baron, R.4
  • 17
    • 85016046312 scopus 로고    scopus 로고
    • Topical menthol: Stability of a sensory profile in a human surrogate model
    • Stengel M, Binder A, Klebe O, et al. Topical menthol: stability of a sensory profile in a human surrogate model. Eur J Pain Suppl 2007;11(Suppl. 1):204-5.
    • (2007) Eur J Pain Suppl , vol.11 , Issue.SUPPL. 1 , pp. 204-205
    • Stengel, M.1    Binder, A.2    Klebe, O.3
  • 18
    • 21344456496 scopus 로고    scopus 로고
    • TRPA1 and TRPM8 activation in humans: Effects of cinnamaldehyde and menthol
    • DOI 10.1097/00001756-200506210-00015
    • Namer B, Seifert F, Handwerker HO, et al. TRPA1 and TRPM8 activation in humans: effects of cinnamaldehyde and menthol. Neuroreport 2005;16:955-9. (Pubitemid 40904746)
    • (2005) NeuroReport , vol.16 , Issue.9 , pp. 955-959
    • Namer, B.1    Seifert, F.2    Handwerker, H.O.3    Maihofner, C.4
  • 19
    • 28844471303 scopus 로고    scopus 로고
    • Distinct expression of TRPM8, TRPA1, and TRPV1 mRNAs in rat primary afferent neurons with Adelta/C-fibers and colocalization with Trk receptors
    • DOI 10.1002/cne.20794
    • Kobayashi K, Fukuoka T, Obata K, et al. Distinct expression of TRPM8, TRPA1, and TRPV1 mRNAs in rat primary afferent neurons with adelta/c-fibers and colocalization with trk receptors. J Comp Neurol 2005;493:596-606. (Pubitemid 41780630)
    • (2005) Journal of Comparative Neurology , vol.493 , Issue.4 , pp. 596-606
    • Kobayashi, K.1    Fukuoka, T.2    Obata, K.3    Yamanaka, H.4    Dai, Y.5    Tokunaga, A.6    Noguchi, K.7
  • 21
    • 51549104880 scopus 로고    scopus 로고
    • Role of TRPM8 and TRPA1 for cold allodynia in patients with cold injury
    • Namer B, Kleggetveit IP, Handwerker H, et al. Role of TRPM8 and TRPA1 for cold allodynia in patients with cold injury. Pain 2008;139:63-72.
    • (2008) Pain , vol.139 , pp. 63-72
    • Namer, B.1    Kleggetveit, I.P.2    Handwerker, H.3
  • 22
    • 44149114440 scopus 로고    scopus 로고
    • TRPA1 receptor localisation in the human peripheral nervous system and functional studies in cultured human and rat sensory neurons
    • Anand U, Otto WR, Facer P, et al. TRPA1 receptor localisation in the human peripheral nervous system and functional studies in cultured human and rat sensory neurons. Neurosci Lett 2008;438:221-7.
    • (2008) Neurosci Lett , vol.438 , pp. 221-227
    • Anand, U.1    Otto, W.R.2    Facer, P.3
  • 25
    • 34548413653 scopus 로고    scopus 로고
    • Use of the novel contact heat evoked potential stimulator (CHEPS) for the assessment of small fibre neuropathy: Correlations with skin flare responses and intra-epidermal nerve fibre counts
    • Atherton DD, Facer P, Roberts KM, et al. Use of the novel contact heat evoked potential stimulator (CHEPS) for the assessment of small fibre neuropathy: correlations with skin flare responses and intra-epidermal nerve fibre counts. BMC Neurol 2007;7:21.
    • (2007) BMC Neurol , vol.7 , pp. 21
    • Atherton, D.D.1    Facer, P.2    Roberts, K.M.3
  • 26
    • 58549111827 scopus 로고    scopus 로고
    • Contact heat evoked potentials using simultaneous EEG and fMRI and their correlation with evoked pain
    • Roberts K, Papadaki A, Goncalves C, et al. Contact heat evoked potentials using simultaneous EEG and fMRI and their correlation with evoked pain. BMC Anesthesiol 2008;8:8.
    • (2008) BMC Anesthesiol , vol.8 , pp. 8
    • Roberts, K.1    Papadaki, A.2    Goncalves, C.3
  • 27
    • 0035909978 scopus 로고    scopus 로고
    • Contact heat evoked potentials as a valid means to study nociceptive pathways in human subjects
    • DOI 10.1016/S0304-3940(01)02374-6, PII S0304394001023746
    • Chen AC, Niddam DM, Arendt-Nielsen L. Contact heat evoked potentials as a valid means to study nociceptive pathways in human subjects. Neurosci Lett 2001;316:79-82. (Pubitemid 34001665)
    • (2001) Neuroscience Letters , vol.316 , Issue.2 , pp. 79-82
    • Chen, A.C.N.1    Niddam, D.M.2    Arendt-Nielsen, L.3
  • 28
    • 3242733089 scopus 로고    scopus 로고
    • Amplitudes of laser evoked potential recorded from primary somatosensory, parasylvian and medial frontal cortex are graded with stimulus intensity
    • DOI 10.1016/j.pain.2004.04.009, PII S0304395904002003
    • Ohara S, Crone NE, Weiss N, et al. Amplitudes of laser evoked potential recorded from primary somatosensory, parasylvian and medial frontal cortex are graded with stimulus intensity. Pain 2004;110:318-28. (Pubitemid 38953297)
    • (2004) Pain , vol.110 , Issue.1-2 , pp. 318-328
    • Ohara, S.1    Crone, N.E.2    Weiss, N.3    Treede, R.-D.4    Lenz, F.A.5
  • 30
    • 33747889354 scopus 로고    scopus 로고
    • Brain processing of the signals ascending through unmyelinated C fibers in humans: An event-related functional magnetic resonance imaging study
    • DOI 10.1093/cercor/bhj071
    • Qiu Y, Noguchi Y, Honda M, et al. Brain processing of the signals ascending through unmyelinated C fibers in humans: an event-related functional magnetic resonance imaging study. Cereb Cortex 2006;16:1289-95. (Pubitemid 44289102)
    • (2006) Cerebral Cortex , vol.16 , Issue.9 , pp. 1289-1295
    • Qiu, Y.1    Noguchi, Y.2    Honda, M.3    Nakata, H.4    Tamura, Y.5    Tanaka, S.6    Sadato, N.7    Wang, X.8    Inui, K.9    Kakigi, R.10
  • 31
    • 37349023979 scopus 로고    scopus 로고
    • Objective Correlate of Subjective Pain Perception by Contact Heat-Evoked Potentials
    • DOI 10.1016/j.jpain.2007.08.010, PII S1526590007008565
    • Granovsky Y, Granot M, Nir RR, et al. Objective correlate of subjective pain perception by contact heat-evoked potentials. J Pain 2008;9:53-63. (Pubitemid 350309733)
    • (2008) Journal of Pain , vol.9 , Issue.1 , pp. 53-63
    • Granovsky, Y.1    Granot, M.2    Nir, R.-R.3    Yarnitsky, D.4
  • 32
    • 0020661425 scopus 로고
    • The effect of capsaicin on the response characteristic of human C-polymodal nociceptors
    • DOI 10.1016/0306-4565(83)90107-9
    • Konietzny F, Hensel H. The effect of capsaicin on the response characteristic of human C-polymodal nociceptors. J Therm Biol 1983;8:213-5. (Pubitemid 13151784)
    • (1983) Journal of Thermal Biology , vol.8 , Issue.1-2 , pp. 213-215
    • Konietzny, F.1    Hensel, H.2
  • 33
    • 0028340936 scopus 로고
    • Different patterns of hyperalgesia induced by experimental inflammation in human skin
    • Kilo S, Schmelz M, Koltzenburg M, et al. Different patterns of hyperalgesia induced by experimental inflammation in human skin. Brain 1994;117:385-96. (Pubitemid 24155510)
    • (1994) Brain , vol.117 , Issue.2 , pp. 385-396
    • Kilo, S.1    Schmelz, M.2    Koltzenburg, M.3    Handwerker, H.O.4
  • 34
    • 0024415770 scopus 로고
    • Heat and mechanical hyperalgesia induced by capsaicin. Cross modality threshold modulation in human C nociceptors
    • Culp WJ, Ochoa J, Cline M, et al. Heat and mechanical hyperalgesia induced by capsaicin. Cross modality threshold modulation in human C nociceptors. Brain 1989;112:1317-31.
    • (1989) Brain , vol.112 , pp. 1317-1331
    • Culp, W.J.1    Ochoa, J.2    Cline, M.3
  • 35
    • 0025744356 scopus 로고
    • Neurogenic hyperalgesia: The search for the primary cutaneous afferent fibers that contribute to capsaicin-induced pain and hyperalgesia
    • Baumann TK, Simone DA, Shain CN, et al. Neurogenic hyperalgesia: the search for the primary cutaneous afferent fibers that contribute to capsaicin-induced pain and hyperalgesia. J Neurophysiol 1991;66:212-27.
    • (1991) J Neurophysiol , vol.66 , pp. 212-227
    • Baumann, T.K.1    Simone, D.A.2    Shain, C.N.3
  • 36
    • 0026508601 scopus 로고
    • Pain, hyperalgesia and activity in nociceptive C units in humans after intradermal injection of capsaicin
    • LaMotte RH, Lundberg LE, Torebjork HE. Pain, hyperalgesia and activity in nociceptive C units in humans after intradermal injection of capsaicin. J Physiol 1992;448:749-64.
    • (1992) J Physiol , vol.448 , pp. 749-764
    • LaMotte, R.H.1    Lundberg, L.E.2    Torebjork, H.E.3
  • 37
    • 0025748690 scopus 로고
    • Early and late effects of prolonged topical capsaicin on cutaneous sensibility and neurogenic vasodilatation in humans
    • Simone DA, Ochoa J. Early and late effects of prolonged topical capsaicin on cutaneous sensibility and neurogenic vasodilatation in humans. Pain 1991;47:285-94.
    • (1991) Pain , vol.47 , pp. 285-294
    • Simone, D.A.1    Ochoa, J.2
  • 38
    • 0031757082 scopus 로고    scopus 로고
    • Ectopic impulse generation and autoexcitation in single myelinated afferent fibers in patients with peripheral neuropathy and positive sensory symptoms
    • DOI 10.1002/(SICI)1097-4598(199812)21:12<1661::AID-MUS6>3.0.CO;2-N
    • Campero M, Serra J, Marchettini P, et al. Ectopic impulse generation and autoexcitation in single myelinated afferent fibers in patients with peripheral neuropathy and positive sensory symptoms. Muscle Nerve 1998;21:1661-7. (Pubitemid 28545695)
    • (1998) Muscle and Nerve , vol.21 , Issue.12 , pp. 1661-1667
    • Campero, M.1    Serra, J.2    Marchettini, P.3    Ochoa, J.L.4
  • 39
    • 0030152528 scopus 로고    scopus 로고
    • Topical capsaicin selectively attenuates heat pain and A delta fiber-mediated laser-evoked potentials
    • Beydoun A, Dyke DB, Morrow TJ, et al. Topical capsaicin selectively attenuates heat pain and A delta fiber-mediated laser-evoked potentials. Pain 1996;65:189-96.
    • (1996) Pain , vol.65 , pp. 189-196
    • Beydoun, A.1    Dyke, D.B.2    Morrow, T.J.3
  • 40
    • 0036289550 scopus 로고    scopus 로고
    • Modulation of trigeminal laser evoked potentials and laser silent periods by homotopical experimental pain
    • DOI 10.1016/S0304-3959(02)00049-0, PII S0304395902000490
    • Romaniello A, Arendt-Nielsen L, Cruccu G, et al. Modulation of trigeminal laser evoked potentials and laser silent periods by homotopical experimental pain. Pain 2002;98:217-28. (Pubitemid 34722484)
    • (2002) Pain , vol.98 , Issue.1-2 , pp. 217-228
    • Romaniello, A.1    Arendt-Nielsen, L.2    Cruccu, G.3    Svensson, P.4
  • 42
    • 77953912593 scopus 로고    scopus 로고
    • The time course of CO(2) laser-evoked responses and of skin nerve fibre markers after topical capsaicin in human volunteers
    • Ragé M, Van Acker N, Facer P, et al. The time course of CO(2) laser-evoked responses and of skin nerve fibre markers after topical capsaicin in human volunteers. Clin Neurophysiol 2010;121:1256-66.
    • (2010) Clin Neurophysiol , vol.121 , pp. 1256-1266
    • Ragé, M.1    Van Acker, N.2    Facer, P.3
  • 43
    • 0024403315 scopus 로고
    • Chronic hyperalgesia and skin warming caused by sensitized C nociceptors
    • Cline MA, Ochoa J, Torebjork HE. Chronic hyperalgesia and skin warming caused by sensitized C nociceptors. Brain 1989;112:621-47. (Pubitemid 19151162)
    • (1989) Brain , vol.112 , Issue.3 , pp. 621-647
    • Cline, M.A.1    Ochoa, J.2    Torebjork, H.E.3
  • 44
    • 38949095201 scopus 로고    scopus 로고
    • Modulation of oral heat and cold pain by irritant chemicals
    • DOI 10.1093/chemse/bjm056
    • Albin KC, Carstens MI, Carstens E. Modulation of oral heat and cold pain by irritant chemicals. Chem Senses 2008;33:3-15. (Pubitemid 351228050)
    • (2008) Chemical Senses , vol.33 , Issue.1 , pp. 3-15
    • Albin, K.C.1    Carstens, M.I.2    Carstens, E.3
  • 45
    • 0037034931 scopus 로고    scopus 로고
    • Identification of a cold receptor reveals a general role for TRP channels in thermosensation
    • DOI 10.1038/nature719
    • McKemy DD, Neuhausser WM, Julius D. Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature 2002;416:52-8. (Pubitemid 34215395)
    • (2002) Nature , vol.416 , Issue.6876 , pp. 52-58
    • McKemy, D.D.1    Neuhausser, W.M.2    Julius, D.3
  • 48
    • 0025163670 scopus 로고
    • Release of cold-induced burning pain by block of cold-specific afferent input
    • Yarnitsky D, Ochoa JL. Release of cold-induced burning pain by block of coldspecific afferent input. Brain 1990;113:893-902. (Pubitemid 20267464)
    • (1990) Brain , vol.113 , Issue.4 , pp. 893-902
    • Yarnitsky, D.1    Ochoa, J.L.2
  • 51
    • 34447342575 scopus 로고    scopus 로고
    • Cold sensitivity of recombinant TRPA1 channels
    • DOI 10.1016/j.brainres.2007.05.047, PII S0006899307011638
    • Sawada Y, Hosokawa H, Hori A, et al. Cold sensitivity of recombinant TRPA1 channels. Brain Res. 2007;1160:39-46. (Pubitemid 47058036)
    • (2007) Brain Research , vol.1160 , Issue.1 , pp. 39-46
    • Sawada, Y.1    Hosokawa, H.2    Hori, A.3    Matsumura, K.4    Kobayashi, S.5
  • 53
    • 39149099084 scopus 로고    scopus 로고
    • Effects of TRPA1 agonists mustard oil and cinnamaldehyde on lumbar spinal wide-dynamic range neuronal responses to innocuous and noxious cutaneous stimuli in rats
    • DOI 10.1152/jn.00883.2007
    • Merrill AW, Cuellar JM, Judd JH, et al. Effects of TRPA1 agonists mustard oil and cinnamaldehyde on lumbar spinal wide-dynamic range neuronal responses to innocuous and noxious cutaneous stimuli in rats. J Neurophysiol 2008;99:415-25. (Pubitemid 351253206)
    • (2008) Journal of Neurophysiology , vol.99 , Issue.2 , pp. 415-425
    • Merrill, A.W.1    Cuellar, J.M.2    Judd, J.H.3    Carstens, M.I.4    Carstens, E.5
  • 55
    • 33646061333 scopus 로고    scopus 로고
    • TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction
    • Kwan KY, Allchorne AJ, Vollrath MA, et al. TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction. Neuron 2006;50:277-89.
    • (2006) Neuron , vol.50 , pp. 277-289
    • Kwan, K.Y.1    Allchorne, A.J.2    Vollrath, M.A.3
  • 56
    • 8144220649 scopus 로고    scopus 로고
    • Two populations of cold-sensitive neurons in rat dorsal root ganglia and their modulation by nerve growth factor
    • DOI 10.1111/j.1460-9568.2004.03695.x
    • Babes A, Zorzon D, Reid G. Two populations of cold-sensitive neurons in rat dorsal root ganglia and their modulation by nerve growth factor. Eur J Neurosci 2004;20:2276-82. (Pubitemid 39472390)
    • (2004) European Journal of Neuroscience , vol.20 , Issue.9 , pp. 2276-2282
    • Babes, A.1    Zorzon, D.2    Reid, G.3
  • 57
    • 17644426325 scopus 로고    scopus 로고
    • Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing
    • DOI 10.1523/JNEUROSCI.0013-05.2005
    • Nagata K, Duggan A, Kumar G, et al. Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing. J Neurosci 2005;25:4052-61. (Pubitemid 40563380)
    • (2005) Journal of Neuroscience , vol.25 , Issue.16 , pp. 4052-4061
    • Nagata, K.1    Duggan, A.2    Kumar, G.3    Garcia-Anoveros, J.4


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