Increased capsaicin receptor TRPV1 in skin nerve fibres and related vanilloid receptors TRPV3 and TRPV4 in keratinocytes in human breast pain

BMC Women's Health

Volumn 5, Issue , 2005, Pages

  Gopinath, Preethi ^a,b   Wan, Elaine ^a,b   Holdcroft, Anita ^b   Facer, Paul ^a   Davis, John B ^c   Smith, Graham D ^c   Bountra, Chas ^c   Anand, Praveen ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b CHELSEA AND WESTMINSTER HOSPITAL   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

NERVE GROWTH FACTOR; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; VANILLOID RECEPTOR; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 3; VANILLOID RECEPTOR 4;

ARTICLE; BREAST RECONSTRUCTION; BREAST REDUCTION; BREAST TENDERNESS; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOLOGY; KERATINOCYTE; MASTALGIA; NERVE FIBER; NERVE INJURY; NERVE SPROUTING; NOCICEPTION; ORGAN SIZE; RECEPTOR BLOCKING; RECEPTOR UPREGULATION; REINNERVATION; SKIN BIOPSY; SKIN NERVE;

EID: 26444436231     PISSN: 14726874     EISSN: 14726874     Source Type: Journal    
DOI: 10.1186/1472-6874-5-2     Document Type: Article

References (25)

1. Wallace MS, Wallace AM, Lee J, Dobke MK: Pain after breast surgery: a survey of 282 women. Pain 1996, 66:195-205.
2. Riley JL, Robinson ME, Wise EA, Price DD: A meta-analytic review of pain perception across the menstrual cycle. Pain 1999, 81:225-235.
3. Holdcroft A: Females and their variability. Anaesthesia 1997, 52:931-934.
4. Morin C, Bushnell MC: Temporal and qualitative properties of cold pain and heat pain: a psychophysical study. Pain 1998, 74:67-73.
5. Robinson JE, Short RV: Changes in breast sensitivity at puberty, during the menstrual cycle, and at parturition. Br Med J 1977, 1:1188-1191.
6. Frascarolo P, Schutz Y, Jequier E: Decreased thermal conductance during the luteal phase of the menstrual cycle in women. J Appl Physiol 1990, 69:2029-2033.
7. Chadbourne EB, Zhang S, Gordon MJ, Ro EY, Ross SD, Schnur PL, Schneider-Redden PR: Clinical outcomes in reduction mammaplasty: a systematic review and meta-analysis of published studies. Mayo Clin Proc 2001, 76:503-510.
8. Macrae WA DHTO: Chronic post-surgical pain. In Epidemiology of Pain Edited by: Crombie IKCPRLSJ. Seattle, IASP Press; 1999.
9. Kroner K, Krebs B, Skov J, Jorgensen HS: Immediate and long-term phantom breast syndrome after mastectomy: incidence, clinical characteristics and relationship to pre-mastectomy breast pain. Pain 1989, 36:327-334.
10. Sohrabji F, Miranda RC, Toran-Allerand CD: Estrogen differentially regulates estrogen and nerve growth factor receptor mRNAs in adult sensory neurons. J Neurosci 1994, 14:459-471.
11. Miranda RC, Sohrabji F, Toran-Allerand D: Interactions of estrogen with the neurotrophins and their receptors during neural development. Horm Behav 1994, 28:367-375.
12. Solum DT, Handa RJ: Estrogen regulates the development of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus. J Neurosci 2002, 22:2650-2659.
13. Anand P: Nerve growth factor regulates nociception in human health and disease. Br J Anaesth 1995, 75:201-208.
14. Lewin GR, Mendell LM: Nerve growth factor and nociception. Trends Neurosci 1993, 16:353-359.
15. Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D: The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 1997, 389:816-824.
16. Davis JB, Gray J, Gunthorpe MJ, Hatcher JP, Davey PT, Overend P, Harries MH, Latcham J, Clapham C, Atkinson K, Hughes SA, Rance K, Grau E, Harper AJ, Pugh PL, Rogers DC, Bingham S, Randall A, Sheardown SA: Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia. Nature 2000, 405:183-187.
17. Benham CD, Gunthorpe MJ, Davis JB: TRPV channels as temperature sensors. Cell Calcium 2003, 33:479-487.
18. Smith GD, Gunthorpe MJ, Kelsell RE, Hayes PD, Reilly P, Facer P, Wright JE, Jerman JC, Walhin JP, Ooi L, Egerton J, Charles KJ, Smart D, Randall AD, Anand P, Davis JB: TRPV3 is a temperature-sensitive vanilloid receptor-like protein. Nature 2002, 418:186-190.
19. Melzack R: The McGill Pain Questionnaire: major properties and scoring methods. Pain 1975, 1:277-299.
20. Chan CL, Facer P, Davis JB, Smith GD, Egerton J, Bountra C, Williams NS, Anand P: Sensory fibres expressing capsaicin receptor TRPV1 in patients with rectal hypersensitivity and faecal urgency. Lancet 2003, 361:385-391.
21. Kennedy AJ, Wellmer A, Facer P, Saldanha G, Kopelman P, Lindsay RM, Anand P: Neurotrophin-3 is increased in skin in human diabetic neuropathy. J Neurol Neurosurg Psychiatry 1998, 65:393-395.
22. Diamond J, Holmes M, Coughlin M: Endogenous NGF and nerve impulses regulate the collateral sprouting of sensory axons in the skin of the adult rat. J Neurosci 1992, 12:1454-1466.
23. Yiangou Y, Facer P, Dyer NH, Chan CL, Knowles C, Williams NS, Anand P: Vanilloid receptor 1 immunoreactivity in inflamed human bowel. Lancet 2001, 357:1338-1339.
24. Watson CP, Evans RJ, Watt VR: The post-mastectomy pain syndrome and the effect of topical capsaicin. Pain 1989, 38:177-186.
25. Walker K GCMSPSPMUL: Capsazepine shows species selective antihyperalgesic effects in models of chronic inflammatory and neuropathic pain. Soc Neurosci Abstr 2001, 27:926-927.