Is theory of mind related to social dysfunction and emotional problems in 22q11.2 deletion syndrome (velo-cardio-facial syndrome)?

Journal of Neurodevelopmental Disorders

Volumn 3, Issue 2, 2011, Pages 152-161

  Campbell, Linda E ^a,b   Stevens, Angela F ^a   McCabe, Kathryn ^c,e   Cruickshank, Lynne ^b   Morris, Robin G ^a   Murphy, Declan G M ^a   Murphy, Kieran C ^d  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF NEWCASTLE   (Australia)

^c UNIVERSITY OF NEWCASTLE   (Australia)

^d ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^e SCHIZOPHRENIA RESEARCH INSTITUTE   (Australia)

Author keywords

22q11.2 deletion syndrome; Social functioning; Social cognition; Social perception; Theory of mind; Velo cardio facial syndrome

Indexed keywords

EID: 79958051201     PISSN: 18661947     EISSN: 18661955     Source Type: Journal    
DOI: 10.1007/s11689-011-9082-7     Document Type: Article

References (49)

1. Andersson F, Glaser B, Spiridon M, Debbané M, Vuilleumier P, Eliez S. Impaired activation of face processing networks revealed by functional magnetic resonance imaging in 22q11. 2 deletion syndrome. Biol Psychiatry. 2008; 63(1): 49-57.
2. Baron-Cohen S, Leslie A, Frith U. Does the autistic child have a "theory of mind"? Cognition. 1985; 21(1): 37-46.
3. Bassett A, Caluseriu O, Weksberg R, Young D, Chow E. Catechol-o-methyl transferase and expression of schizophrenia in 73 adults with 22q11 deletion syndrome. Biol Psychiatry. 2007; 61: 1135-40.
4. Bishop DVM. The test for reception of grammar (TROG). 2nd edition. Published by the author and available from Age and Cognitive Performance Research Centre, University of Manchester, M13 9PL, UK; 1983.
5. Bruce V, Young A. Understanding face recognition. Br J Psychol. 1986; 77: 305-27.
6. Bruce V, Campbell RN, Doherty-Sneddon G, Import A, Langton S, McAuley S, et al. Testing face processing skills in children. Br J Dev Psychol. 2000; 18: 319-33.
7. Campbell L. Brain, behaviour and cognition in 22q11. 2 deletion syndrome (22qDS). London: University of London, King's College London; 2006.
8. Campbell L, Daly E, Toal F, Stevens A, Azuma R, Catani M, et al. Brain and behaviour in children with 22q11. 2 deletion syndrome: a volumetric and voxel-based morphometry MRI study. Brain. 2006; 129(5): 1218-28.
9. Campbell L, Stevens A, Daly E, Toal F, Azuma R, Karmiloff-Smith A, et al. A comparative study of cognition and brain anatomy between two neurodevelopmental disorders: 22q11. 2 deletion syndrome and Williams syndrome. Neuropsychologia. 2009; 47(4): 1034-44.
10. Campbell L, McCabe K, Leadbeater K, Schall U, Loughland C, Rich D. Visual scanning of faces in 22q11. 2 deletion syndrome: attention to the mouth or the eyes? Psychiatry Res. 2010a; 177(1-2): 211-5.
11. Campbell L, McCabe K, Leadbeater K, Schall U, Loughland C, Rich D. Visual scanning of faces in 22q11. 2 deletion syndrome: Attention to the mouth or the eyes? Psychiatry Research. 2010; 177(1-2): 211-5. doi: 10. 1016/j. psychres. 2009. 06. 007.
12. Castelli F, Frith C, Happe F, Frith U. Autism, Asperger syndrome and brain mechanisms for the attribution of mental states to animated shapes. Brain. 2002; 125: 1839-49.
13. Chow E, Watson M, Young D, Bassett A. Neurocognitive profile in 22q11 deletion syndrome and schizophrenia. Schizophr Res. 2006; 87: 270-8.
14. Dunn LM, Whetton C, Burley J. The British picture vocabulary scale (2nd edition). NFER-Nelson Publishing company Ltd, UK; 1982.
15. Fine S, Weissman A, Gerdes M, Pinto-Martin J, Zackai E, McDonald-McGinn D, et al. Autism spectrum disorders and symptoms in children with molecularly confirmed 22q11. 2 deletion syndrome. J Autism Dev Disord. 2005; 35(4): 461-70.
16. Golding-Kushner K, Weller G, Shprintzen R. Velo-cardio-facial syndrome: language and psychological profiles. J Craniofac Genet Dev Biol. 1985; 5(3): 259-66.
17. Goodman R, Ford T, Simmons H, Gatward R, Meltzer H. Using the strengths and difficulties questionnaire (SDQ) to screen for child psychiatric disorders in a community sample. Br J Psychiatry. 2000; 177: 534-9.
18. Gopnik A, Astington J. Children's understanding of representational change and its relation to the understanding of false belief and the appearance reality distinction. Child Dev. 1988; 59: 26-37.
19. Gothelf D, Presburger G, Levy D, Nahmani A, Burg M, Berant M, et al. Genetic, developmental, and physical factors associated with attention deficit hyperactivity disorder in patients with velocardiofacial syndrome. Am J Med Genet B Neuropsychiatr Genet. 2004; 126B(1): 116-21.
20. Happé F. Autism, an introduction to psychological theory. London: UCL Press Ltd; 1994.
21. Haxby J, Hoffman E, Gobbini I. The distributed human neural system for face perception. Trends Cogn Sci. 2000; 4: 223-33.
22. Heineman-de Boer J, van Haelst M, Cordia-de Haan M, Beemer F. Behavior problems and personality aspects of 40 children with velo-cardio-facial syndrome. Genet Couns. 1999; 1: 1089-93.
23. Henry J, van Amelsvoort T, Morris R, Owen M, Murphy D, Murphy K. An investigation of the neuropsychological profile in adults with velo-cardio-facial syndrome (VCFS). Neuropsychologia. 2002; 40(5): 471-8.
24. Hughes C, Adlam A, Happe F, Jackson J, Taylor A, Caspi A. Good test-retest reliability for standard and advanced false-belief tasks across a wide range of abilities. J Child Psychol Psychiatry. 2000; 41: 483-90.
25. Iarocci G, Yager J, Elfers T. What gene-environment interactions can tell us about social competence in typical and atypical populations. Brain Cogn. 2007; 65: 112-27.
26. Jablensky A. Epidemiology of schizophrenia: the global burden of disease and disability. Eur Arch Psychiatry Clin Neurosci. 2000; 250(6): 274-85.
27. Jolliffe T, Baron-Cohen S. The Strange Stories test: a replication with high-functioning adults with autism or Asperger syndrome. J Autism Dev Disord. 1999; 29(5): 395-406.
28. Kiley-Brabeck K, Sobin C. Social skills and executive function deficits in children with the 22q11 deletion syndrome. Appl Neuropsychol. 2006; 13: 258-68.
29. Lajiness-O'Neill R, Beaulieu I, Titus J, Asamoah A, Bigler E, Bawle E. Memory and learning in children with 22q11. 2 deletion syndrome: evidence for ventral and dorsal stream disruption? Child Neuropsychology. 2005; 11(1): 55-71.
30. Murphy K. Schizophrenia and velo-cardio-facial syndrome. Lancet. 2002; 359(9304): 426-30.
31. Murphy K. Annotation: velo-cardio-facial syndrome. J Child Psychol Psychiatry. 2005; 45(6): 563-71.
32. Niklasson L, Rasmussen P, Oskarsdottir S, Gillberg C. Chromosome 22q11 deletion syndrome (CATCH 22): neuropsychiatric and neuropsychological aspects. Dev Med Child Neurol. 2002; 44: 44-50.
33. Perner J, Wimmer H. John thinks that mary thinks that-attribution of 2nd-order beliefs by 5-Year-Old to 10-Year-Old Children. J Exp Child Psychol. 1985; 39(3): 437-71.
34. Posamentier M, Abdi H. Processing faces and facial expressions. Neuropsychol Rev. 2003; 13(3): 113-43.
35. Premack D, Woodruff G. Does the chimpanzee have a theory of mind? Behav Brain Sci. 1978; 1: 515-26.
36. Sands JR, Harrow M. Vulnerability to psychosis in unipolar major depression: is premorbid functioning involved? Am J Psychiatry. 1995; 152(7): 1009-15. 1995 July 1.
37. Shprintzen R. Velo-cardio-facial syndrome: a distinctive behavioural phenotype. Ment Retard Dev Disabil Res Rev. 2000; 6(2): 142-7.
38. Shprintzen R. Velo-cardio-facial syndrome. Prog Pediatr Cardiol. 2005; 20: 187-93.
39. Siegal M, Varley R. Neural systems involved in "theory of mind". Nature Review Neuroscience. 2002; 3(6): 463-71.
40. Swillen A, Devriendt K, Legius E, Eyskens B, Dumoulin M, Gewillig M, et al. Intelligence and psychosocial adjustment in velocardiofacial syndrome: a study of 37 children and adolescents with VCFS. J Med Genet. 1997; 34(6): 453-8.
41. Swillen A, Devriendt K, Legius E, Prinzie P, Vogels A, Ghesquiere P. The behavioural phenotype in velo-cardio-facial syndrome (VCFS): from infancy to adolescence. Genet Couns. 1999; 10(1): 79-88.
42. Swillen A, Vogels A, Devriendt K, Fryns JP. Chromosome 22q11 deletion syndrome: update and review of the clinical features, cognitive-behavioral spectrum, and psychiatric complications. Am J Med Genet. 2000; 97: 128-35.
43. Tager-Flusberg H, Sullivan K. A componential view of theory of mind: evidence from Williams syndrome. Cognition. 2000; 76: 59-89.
44. Tager-Flusberg H, Plesa-Skwerer D, Faja S, Joseph R. People with Williams syndrome process faces holistically. Cognition. 2003; 89: 11-24.
45. van Amelsvoort T, Daly E, Robertson D, Suckling J, Ng V, Critchley H, Owen M, Henry J, Murphy KC, Murphy DGM. Structural brain abnormalities associated with deletion at chromosome 22q11: quantitative neuroimaging study of adults with velo-cardio-facial syndrome. Br J Psych. 2001; 178: 412-419.
46. van Amelsvoort T, Schmitz N, Daly E, Deeley Q, Critchley H, Henry J, et al. Processing facial emotions in adults with velo-cardio-facial syndrome: functional magnetic resonance imaging. Br J Psychiatry. 2006; 189: 560-1.
47. Vorstman J, Morcus M, Duijff S, Klaassen P, Heineman-de Boer J, Beemer F. The 22q11. 2 deletion in children: high rate of autistic disorders and early onset of psychotic symptoms. J Am Acad Child Adolesc Psychiatry. 2006; 45(9): 1104-13.
48. Wang Y-G, Wang Y-Q, Chen S-L, Zhu C-Y. Theory of mind disability in major depression with or without psychotic symptoms: a componential view. Psychiatry Res. 2008; 161(2): 153-61.
49. Wechsler D. Wechsler Intelligence Scales for Children-third edition. San Antonio, Texas: The Psychological Corporation; 1991.