Visual scanning of faces in 22q11.2 deletion syndrome: Attention to the mouth or the eyes?

Psychiatry Research

Volumn 177, Issue 1-2, 2010, Pages 211-215

  Campbell, Linda ^a,b,c   McCabe, Kathryn ^a,b   Leadbeater, Kate ^a   Schall, Ulrich ^a,b,c   Loughland, Carmel ^a,b,c   Rich, Dominique ^a  

^a UNIVERSITY OF NEWCASTLE   (Australia)

^b SCHIZOPHRENIA RESEARCH INSTITUTE   (Australia)

^c HUNTER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

Emotion face processing; Eye gaze avoidance; Social functioning; Visual scanpaths

Indexed keywords

ACCURACY; ADOLESCENT; AFFECT; ARTICLE; AUTISM; CHROMOSOME 22Q; CHROMOSOME DELETION; CHROMOSOME DELETION 22; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; EMOTIONALITY; EYE FIXATION; FACIAL EXPRESSION; FEAR; FEMALE; GAZE; HUMAN; INFORMATION PROCESSING; INTERPERSONAL STRESS; MALE; PATTERN RECOGNITION; PRIORITY JOURNAL; SCHIZOPHRENIA; SOCIAL ADAPTATION; SOCIAL ENVIRONMENT; SOCIAL INTERACTION; VISUAL INFORMATION; VISUAL STIMULATION;

ADOLESCENT; ATTENTION; CHROMOSOME ABERRATIONS; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 22; EYE; FACIAL EXPRESSION; FEMALE; HUMANS; MALE; MOUTH; NEUROPSYCHOLOGICAL TESTS; PATTERN RECOGNITION, VISUAL; PHOTIC STIMULATION; YOUNG ADULT;

EID: 77952095336     PISSN: 01651781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.psychres.2009.06.007     Document Type: Article

References (39)

1. Adams R., Gordon H., Baird A., Ambady N., Kleck R. Effects of gaze on amygdala sensitivity to anger and fear faces. Science and Justice 2003, 300:1536.
2. Adolphs R. Neural systems for recognizing emotion. Current Opinion in Neurobiology 2002, 12:169-177.
3. Adolphs R. Fear, faces and the human amygdala. Current Opinion in Neurobiology 2008, 18:166-172.
4. Andersson F., Glaser B., Spiridon M., Debbané M., Vuilleumier P., Eliez S. Impaired activation of face processing networks revealed by functional magnetic resonance imaging in 22q11.2 deletion syndrome. Biological Psychiatry 2008, 63:49-57.
5. Ashwin C., Chapman E., Colle L., Baron-Cohen S. Impaired recognition of negative basic emotions in autism: a test of the amygdala theory. Social Neuroscience 2006, 1:349-363.
6. Ashwin C., Baron-Cohen S., Wheelwright S., O'Riordan M., Bullmore E. Differential activation of the amygdala and the 'social brain' during fearful face-processing in Asperger Syndrome. Neuropsychologia 2007, 45:2-14.
7. Campbell L., Daly E., Toal F., Stevens A., Azuma R., Catani M., Ng V., van Amelsvoort T., Chitnis X., Cutter W., Murphy D., Murphy K. Brain and behaviour in children with 22q11.2 deletion syndrome: a volumetric and voxel-based morphometry MRI study. Brain 2006, 129:1218-1228.
8. Campbell L., Stevens A., Daly E., Toal F., Azuma R., Karmiloff-Smith A., Murphy D., Murphy K. A comparative study of cognition and brain anatomy between two neurodevelopmental disorders: 22q11.2 deletion syndrome and Williams syndrome. Neuropsychologia 2009, 47:1034-1044. Issue.
9. Dalton K., Nacewicz B., Johnstone T., Schaefer H., Gernsbacher M., Goldsmith H., Alexander A., Davidson R. Gaze fixation and the neural circuitry of face processing in autism. Nature Neuroscience 2005, 8:519-526.
10. Deboer T., Wu Z., Lee A., Simon T. Hippocampal volume reduction in children with chromosome 22q11.2 deletion syndrome is associated with cognitive impairment. Behavioural and Brain Functions 2007, 54.
11. Emery N. The eyes have it: the neuroethology, function and evolution of social gaze. Neuroscience and Biobehavioral Reviews 2000, 24:581-604.
12. Fine S., Weissman A., Gerdes M., Pinto-Martin J., Zackai E., McDonald-McGinn D., Emanuel B. Autism spectrum disorders and symptoms in children with molecularly confirmed 22q11.2 deletion syndrome. Journal of Autism and Developmental Disorders 2005, 35:461-470.
13. Gerdes M., Solot C., Wang P.P., Moss E., LaRossa D., Randall P., Goldmuntz E., Clark B., Driscoll D.A., Jawad A., Emanuel B.S., McDonald-McGinn D.M., Batshaw M.L., Zackai E. Cognitive and behaviour profile of pre-school children with chromosome 22q11.2 deletion. American Journal of Medical Genetics 1999, 85:127-133.
14. Golding-Kushner K., Weller G., Shprintzen R. Velo-cardio-facial syndrome: language and psychological profiles. Journal of Craniofacial Genetics and Developmental Biology 1985, 5:259-266.
15. Gur R., Loughead J., Kohler C., Elliott M., Lesko K., Ruparel K., Wolf D., Bilker W., Gur R. Limbic activation associated with misidentification of fearful faces and flat affect in schizophrenia. Archives of General Psychiatry 2007, 64:1356-1366.
16. Jemel B., Mottron L., Dawson M. Impaired face processing in autism: fact or artifact?. Journal of Autism and Developmental Disorders 2006, 36:91-106.
17. LeDoux J.E. Emotion: cues from the brain. Annual Review of Psychology 1995, 46:209-235.
18. Loughland C., Williams L., Gordon E. Visual scanpaths to positive and negative facial emotion in an outpatient schizophrenic sample. Schizophrenia Research 2002, 55:159-170.
19. Mazzola F., Seigal A., MacAskill A., Corden B., Lawrence K., Skuse D. Eye tracking and fear recognition deficits in Turner syndrome. Social Neuroscience 2006, 1:259-269.
20. Morris J.S., Frith C.D., Perret D.I., Rowland D., Young A.W., Calder A.J., Dolan R.J. A differential neural response in the human amygdala to fearful and happy facial expressions. Nature 1996, 383:812-815.
21. Morris J., deBonis M., Dolan R. Human amygdala responses to fearful eyes. Neuroimage 2002, 17:214-222.
22. Murphy K.C., Jones L.A., Owen M.J. High rates of schizophrenia in adults with velo-cardio-facial syndrome. Archives of General Psychiatry 1999, 56:940-945.
23. Niklasson L., Rasmussen P., Oskarsdottir S., Gillberg C. Neuropsychiatric disorders in the 22q11 deletion syndrome. Genetics in Medicine 2001, 3:79-84.
24. Oscarsdottir S., Vujic M., Fasth A. Incidence and prevalence of the 22q11 deletion syndrome: a population-based study in Western Sweden. Archives of Disease in Childhood 2004, 89:148-151.
25. Phillips M., Drevets W., Rauch S., Lane R. Neurobiology of emotion perception I: the neural basis of normal emotion perception. Biological Psychiatry 2003, 54:504-514.
26. Rotshtein P., Malach R., Hadar U., Graif M., Hendler T. Feeling or features: different sensitivity to emotion in high-order visual cortex and amygdala. Neuron 2001, 32:747-757.
27. Sasson N. The development of face processing in autism. Journal of Autism and Developmental Disorders 2006, 36:381-394.
28. Smith M., Cottrell G., Gosselin F., Schyns P. Transmitting and decoding facial expressions. Psychol Sci 2005, 16:184-189.
29. Spezio M., Huang P., Castelli F., Adolphs R. Amygdala damage impairs eye contact during conversations with real people. Journal of Neuroscience 2007, 27:3994-3997.
30. Swillen A., Devriendt K., Legius E., Prinzie P., Vogels A., Ghesquiere, Fryns J.P. The behavioural phenotype in velo-cardio-facial syndrome (VCFS): from infancy to adolescence. Genetic Counseling 1999, 10:79-88.
31. Swillen A., Vandeputte L., Cracco J., Maes B., Ghesquiere P., Devriendt K., Fryns J. Neuropsychological, learning and psychosocial profile of primary school aged children with the velo-cardio-facial syndrome (22q11 deletion): evidence for a nonverbal learning disability?. Child Neuropsychology 1999, 5:230-241.
32. Tanaka J.W., Farah M.J. The holistic representation of faces. Perception of Faces, Objects and Scenes: Analytic and Holistic Processes 2003, Oxford University Press, New York, NY. M.A. Peterson, G. Rhodes (Eds.).
33. Tottenham N., Tanaka J., Leon A., McCarry T., Nurse M., Hare T., Marcus D., Westerlund A., Casey B., Nelson C. The NimStim set of facial expressions: judgments from untrained research participants. Psychiatry Research 2009, 168(3):242-249.
34. van Amelsvoort T., Schmitz N., Daly E., Deeley Q., Critchley H., Henry J., Robertson D., Owen M., Murphy K., Murphy D. Processing facial emotions in adults with velo-cardio-facial syndrome: functional magnetic resonance imaging. British Journal of Psychiatry 2006, 189:560-561.
35. Vorstman J., Morcus M., Duijff S., Klaassen P., Heineman-de Boer J., Beemer F., Swaab H., Kahn R., van Engeland H. The 22q11.2 deletion in children: high rate of autistic disorders and early onset of psychotic symptoms. Journal of the American Academy of Child and Adolescent Psychiatry 2006, 45:1104-1113.
36. Vuilleumier P., Pourtois G. Distributed and interactive brain mechanisms during emotion face perception: evidence from functional neuroimaging. Neuropsychologia 2007, 45:174-194.
37. Wechsler D. Wechsler Abbreviated Scale of Intelligence (WASI) 1999, Harcourt Assessment, San Antonio.
38. Williams L., Loughland C., Gordon E., Davidson D. Visual scanpaths in schizophrenia: is there a deficit in face recognition?. Schizophrenia Research 1999, 36:189-199.
39. Young A.W., Hellawell D., Hay D.C. Configurational information in face perception. Perception 1987, 16:747-759.