In vivo stem cell tracking in neurodegenerative therapies

Expert Opinion on Biological Therapy

Volumn 11, Issue 7, 2011, Pages 911-920

  Bhakoo, Kishore ^a  

^a AGENCY FOR SCIENCE   (Singapore)

Author keywords

contrast agents; MRI; neurodegeneration; Parkinson's disease; stem cells

Indexed keywords

BROXURIDINE; DEXTRAN; FLUORINE; GADOLINIUM PENTETATE; RHODAMINE; SUPERPARAMAGNETIC IRON OXIDE; ULTRASMALL SUPERPARAMAGNETIC IRON OXIDE;

ADULT STEM CELL; CELL LABELING; CELL MIGRATION; CELL TRACKING; CONTRAST ENHANCEMENT; DEGENERATIVE DISEASE; DRUG UPTAKE; EMBRYONIC STEM CELL; HUMAN; IN VIVO STUDY; MESENCHYMAL STEM CELL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; REVIEW; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STEM CELL TRANSPLANTATION;

ANIMALS; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; CELL TRACKING; CENTRAL NERVOUS SYSTEM; CONTRAST MEDIA; HUMANS; MAGNETIC RESONANCE IMAGING; NERVE REGENERATION; NEURODEGENERATIVE DISEASES; NEURONS; STEM CELL TRANSPLANTATION; TREATMENT OUTCOME;

EID: 79958047001     PISSN: 14712598     EISSN: None     Source Type: Journal    
DOI: 10.1517/14712598.2011.575057     Document Type: Review

References (62)

1. Rosser AE, Zietlow R, Dunnett SB. Stem cell transplantation for neurodegenerative diseases. Curr Opin Neurol 2007;20:688-92 (Pubitemid 350085011)
2. Piccini P, Brooks DJ, Bjorklund A, et al. Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient. Nat Neurosci 1999;2:1137-40. (Pubitemid 30126374)
3. Ourednik J, Ourednik V, Lynch WP, et al. Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons. Nat Biotechnol 2002;20:1103-10 (Pubitemid 35285438)
4. Yamamoto S, Yamamoto N, Kitamura T, et al. Proliferation of parenchymal neural progenitors in response to injury in the adult rat spinal cord. Exp Neurol 2001;172:115-27 (Pubitemid 33141159)
5. Shibuya S, Miyamoto O, Auer RN, et al. Embryonic intermediate filament, nestin, expression following traumatic spinal cord injury in adult rats. Neuroscience 2002;114:905-16
6. Galli R, Borello U, Gritti A, et al. Skeletal myogenic potential of human and mouse neural stem cells. Nat Neurosci 2000;3:986-91
7. Noble M, Mayer-Proschel M. Glial-restricted progenitors. In: Rao MS, editor, Stem cells and CNS development. Humana Press, Totowa, NJ; 2001. p. 123-51
8. Kawasaki H, Mizuseki K, Nishikawa S, et al. Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. Neuron 2000;28:31-40
9. Lee SH, Lumelsky N, Studer L, et al. Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells. Nat Biotechnol 2000;18:675-9 (Pubitemid 30415305)
10. Reubinoff BE, Itsykson P, Turetsky T, et al. Neural progenitors from human embryonic stem cells. Nat Biotechnol 2001;19:1134-40 (Pubitemid 33115699)
11. Liu S, Qu Y, Stewart TJ, et al. Embryonic stem cells differentiate into oligodendrocytes and myelinate in culture and after spinal cord transplantation. Proc Natl Acad Sci USA 2000;97:6126-31 (Pubitemid 30367534)
12. Stavridis MP, Smith AG. Neural differentiation of mouse embryonic stem cells. Biochem Soc Trans 2003;31:45-9 (Pubitemid 36241395)
13. Zhang SC, Li XJ, Johnson MA, Pankratz MT. Human embryonic stem cells for brain repair? Philos Trans R Soc Lond B Biol Sci 2008;363:87-99 (Pubitemid 350174575)
14. Weimann JM, Charlton CA, Brazelton TR, et al. Contribution of transplanted bone marrow cells to Purkinje neurons in human adult brains. Proc Natl Acad Sci USA 2003;100:2088-93 (Pubitemid 36254578)
15. Jiang Y, Jahagirdar BN, Reinhardt RL, et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002;418:41-9 (Pubitemid 34742565)
16. Herrera DG, Garcia-Verdugo JM, Alvarez-Buylla A. Adult-derived neural precursors transplanted into multiple regions in the adult brain. Ann Neurol 1999;46:867-77
17. Caplan AI, Dennis JE. Mesenchymal stem cells as trophic mediators. J Cell Biochem 2006;98:1076-84 (Pubitemid 44128350)
18. Chen J, Li Y, Wang L, et al. Therapeutic benefit of intracerebral transplantation of bone marrow stromal cells after cerebral ischemia in rats. J Neurol Sci 2001;189:49-57 (Pubitemid 32776649)
19. Chen X, Katakowski M, Li Y, et al. Human bone marrow stromal cell cultures conditioned by traumatic brain tissue extracts: growth factor production. J Neurosci Res 2002;69:687-91 (Pubitemid 34966882)
20. Martino G, Pluchino S. The therapeutic potential of neural stem cells. Nat Rev Neurosci 2006;7:395-406
21. Redmond DE Jr, Bjugstad KB, Teng YD, et al. Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells. Proc Natl Acad Sci USA 2007;104:12175-80 (Pubitemid 47185649)
22. Lagasse E, Connors H, Al-Dhalimy M, et al. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat Med 2000;6:1229-34
23. Orlic D, Kajstura J, Chimenti S, et al. Bone marrow cells regenerate infarcted myocardium. Nature 2001;410:701-5 (Pubitemid 32290358)
24. Bengel FM, Schachinger V, Dimmeler S. Cell-based therapies and imaging in cardiology. Eur J Nucl Med Mol Imaging 2005;32(Suppl 2):S404-16 (Pubitemid 41796403)
25. Heyn C, Bowen CV, Rutt BK, Foster PJ. Detection threshold of single SPIO-labeled cells with FIESTA. Magn Reson Med 2005;53:312-20 (Pubitemid 40171045)
26. Hinds KA, Hill JM, Shapiro EM, et al. Highly efficient endosomal labeling of progenitor and stem cells with large magnetic particles allows magnetic resonance imaging of single cells. Blood 2003;102:867-72 (Pubitemid 36917777)
27. Shapiro EM, Sharer K, Skrtic S, Koretsky AP. In vivo detection of single cells by MRI. Magn Reson Med 2006;55:242-9. (Pubitemid 43238090)
28. Shapiro EM, Skrtic S, Koretsky AP. Sizing it up: cellular MRI using micron-sized iron oxide particles. Magn Reson Med 2005;53:329-38 (Pubitemid 40171047)
29. Shapiro EM, Skrtic S, Sharer K, et al. MRI detection of single particles for cellular imaging. Proc Natl Acad Sci USA 2004;101:10901-6 (Pubitemid 38989558)
30. Louie AY, Huber MM, Ahrens ET, et al. In vivo visualization of gene expression using magnetic resonance imaging. Nat Biotechnol 2000;18:321-5
31. Josephson L, Tung CH, Moore A, Weissleder R. High-efficiency intracellular magnetic labeling with novel superparamagnetic-Tat peptide conjugates. Bioconjug Chem 1999;10:186-91 (Pubitemid 29147720)
32. Bhorade R, Weissleder R, Nakakoshi T, et al. Macrocyclic chelators with paramagnetic cations are internalized into mammalian cells via a HIV-tat derived membrane translocation peptide. Bioconjug Chem 2000;11:301-5 (Pubitemid 30324895)
33. Lewin M, Carlesso N, Tung CH, et al. Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells. Nat Biotechnol 2000;18:410-14 (Pubitemid 30217528)
34. Chapon C, Jackson JS, Aboagye EO, et al. An in vivo multimodal imaging study using MRI and PET of stem cell transplantation after myocardial infarction in rats. Mol Imaging Biol 2009;11:31-8
35. Srinivas M, Aarntzen EH, Bulte JW, et al. Imaging of cellular therapies. Adv Drug Deliv Rev 2010;62:1080-93
36. Merbach AE, Toth E. The chemistry of contrast agents in medical magentic resonance imaging. John Wiley and Sons, Chichester, UK; 2001
37. Wunderbaldinger P, Josephson L, Weissleder R. Crosslinked iron oxides (CLIO): a new platform for the development of targeted MR contrast agents. Acad Radiol 2002;9(Suppl 2):S304-6 (Pubitemid 34857701)
38. Bulte JW, Arbab AS, Douglas T, Frank JA. Preparation of magnetically labeled cells for cell tracking by magnetic resonance imaging. Methods Enzymol 2004;386:275-99 (Pubitemid 38657598)
39. Babic M, Horak D, Trchova M, et al. Poly(L-lysine)-modified iron oxide nanoparticles for stem cell labeling. Bioconjug Chem 2008;19:740-50 (Pubitemid 351431406)
40. Arbab AS, Yocum GT, Kalish H, et al. Efficient magnetic cell labeling with protamine sulfate complexed to ferumoxides for cellular MRI. Blood 2004;104:1217-23 (Pubitemid 39038047)
41. Dodd SJ, Williams M, Suhan JP, et al. Detection of single mammalian cells by high-resolution magnetic resonance imaging. Biophys J 1999;76:103-9 (Pubitemid 29202442)
42. Schoepf U, Marecos EM, Melder RJ, et al. Intracellular magnetic labeling of lymphocytes for in vivo trafficking studies. BioTechniques 1998;24:642-6, 648-651
43. Sipe JC, Filippi M, Martino G, et al. Method for intracellular magnetic labeling of human mononuclear cells using approved iron contrast agents. Magn Reson Imaging 1999;17:1521-3
44. Weissleder R, Cheng HC, Bogdanova A, Bogdanov A Jr. Magnetically labeled cells can be detected by MR imaging. J Magn Reson Imaging 1997;7:258-63 (Pubitemid 28365670)
45. Yeh TC, Zhang W, Ildstad ST, Ho C. Intracellular labeling of T-cells with superparamagnetic contrast agents. Magn Reson Med 1993;30:617-25 (Pubitemid 23317319)
46. Yeh TC, Zhang W, Ildstad ST, Ho C. In vivo dynamic MRI tracking of rat T-cells labeled with superparamagnetic iron-oxide particles. Magn Reson Med 1995;33:200-8
47. Bulte JW, Ma LD, Magin RL, et al. Selective MR imaging of labeled human peripheral blood mononuclear cells by liposome mediated incorporation of dextran-magnetite particles. Magn Reson Med 1993;29:32-7 (Pubitemid 23063066)
48. Bulte JW, Laughlin PG, Jordan EK, et al. Tagging of T cells with superparamagnetic iron oxide: uptake kinetics and relaxometry. Acad Radiol 1996;3(Suppl 2):S301-3
49. Daldrup-Link HE, Rudelius M, Oostendorp RA, et al. Targeting of hematopoietic progenitor cells with MR contrast agents. Radiology 2003;228:760-7 (Pubitemid 37025487)
50. Bulte JW, Zhang S, van Gelderen P, et al. Neurotransplantation of magnetically labeled oligodendrocyte progenitors: magnetic resonance tracking of cell migration and myelination. Proc Natl Acad Sci USA 1999;96:15256-61 (Pubitemid 30019799)
51. Berry CC, Charles S, Wells S, et al. The influence of transferrin stabilised magnetic nanoparticles on human dermal fibroblasts in culture. Int J Pharm 2004;269:211-25 (Pubitemid 38032835)
52. Dunning MD, Lakatos A, Loizou L, et al. Superparamagmetic iron oxide-labeled Schwann cells and olfactory ensheating cells can be traced in vivo by magnetioc resonance imaging and retain functional properties after transplantation into the CNS. J Neurosci 2004;24:9799-810 (Pubitemid 39463561)
53. Arbab AS, Yocum GT, Rad AM, et al. Labeling of cells with ferumoxides-protamine sulfate complexes does not inhibit function or differentiation capacity of hematopoietic or mesenchymal stem cells. NMR Biomed 2005;18:553-5
54. Zhang RL, Zhang L, Zhang ZG, et al. Migration and differentiation of adult rat subventricular zone progenitor cells transplanted into the adult rat striatum. Neuroscience 2003;116:373-82 (Pubitemid 36139909)
55. Modo M, Mellodew K, Cash D, et al. Mapping transplanted stem cell migration after a stroke: a serial, in vivo magnetic resonance imaging study. Neuroimage 2004;21:311-17 (Pubitemid 38115022)
56. Hoehn M, Kustermann E, Blunk J, et al. Monitoring of implanted stem cell migration in vivo: a highly resolved in vivo magnetic resonance imaging investigation of experimental stroke in rat. Proc Natl Acad Sci USA 2002;99:16267-72 (Pubitemid 35462784)
57. Jendelova P, Herynek V, Urdzikova L, et al. Magnetic resonance tracking of transplanted bone marrow and embryonic stem cells labeled by iron oxide nanoparticles in rat brain and spinal cord. J Neurosci Res 2004;76:232-43 (Pubitemid 38451211)
58. Urdzikova L, Jendelova P, Glogarova K, et al. Transplantation of bone marrow stem cells as well as mobilization by granulocyte-colony stimulating factor promotes recovery after spinal cord injury in rats. J Neurotrauma 2006;23:1379-91 (Pubitemid 46489623)
59. Guzman R, Uchida N, Bliss TM, et al. Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI. Proc Natl Acad Sci USA 2007;104:10211-16 (Pubitemid 47175288)
60. Modo M, Beech JS, Meade TJ, et al. A chronic 1 year assessment of MRI contrast agent-labelled neural stem cell transplants in stroke. Neuroimage 2009;47(Suppl 2):T133-42
61. Jackson J, Chapon C, Jones W, et al. In vivo multimodal imaging of stem cell transplantation in a rodent model of Parkinson's disease. J Neurosci Methods 2009;183141-8
62. Taupitz M, Schmitz S, Hamm B. Superparamagnetic iron oxide particles: current state and future development. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr 2003;175:752-65 (Pubitemid 36806756)