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Volumn 11, Issue 2, 2011, Pages 118-127

High-dose testosterone propionate treatment reverses the effects of endurance training on myocardial antioxidant defenses in adolescent male rats

Author keywords

Adolescence; Antioxidant enzymes; Endurance training; Heart; Nonenzymatic antioxidants; Oxidative stress; Testosterone; Tocopherols

Indexed keywords

ALPHA TOCOPHEROL; CATALASE; GAMMA TOCOPHEROL; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; MALONALDEHYDE; SEX HORMONE; SUPEROXIDE DISMUTASE; TESTOSTERONE PROPIONATE;

EID: 79958034039     PISSN: 15307905     EISSN: 15590259     Source Type: Journal    
DOI: 10.1007/s12012-011-9105-3     Document Type: Article
Times cited : (38)

References (42)
  • 1
    • 50449111231 scopus 로고    scopus 로고
    • Regulation of coronary blood flow during exercise
    • 18626066 10.1152/physrev.00045.2006 1:CAS:528:DC%2BD1cXpslKgsLo%3D
    • DJ Duncker RJ Bache 2008 Regulation of coronary blood flow during exercise Physiological Reviews 88 1009 1086 18626066 10.1152/physrev.00045.2006 1:CAS:528:DC%2BD1cXpslKgsLo%3D
    • (2008) Physiological Reviews , vol.88 , pp. 1009-1086
    • Duncker, D.J.1    Bache, R.J.2
  • 2
    • 0005280130 scopus 로고    scopus 로고
    • Exercise-induced oxidative stress in the heart
    • C.K. Sen L. Packer O. Hänninen (eds). Elsevier B.V. Amsterdam. 10.1016/B978-044482650-3/50025-0
    • Ji, L. L. (2000). Exercise-induced oxidative stress in the heart. In C. K. Sen, L. Packer, & O. Hänninen (Eds.), Handbook of oxidants and antioxidants in exercise (pp. 689-711). Amsterdam: Elsevier B.V.
    • (2000) Handbook of Oxidants and Antioxidants in Exercise , pp. 689-711
    • Ji, L.L.1
  • 3
    • 0033817812 scopus 로고    scopus 로고
    • Free radical generation and oxidative stress with ageing and exercise: Differential effects in the myocardium and liver
    • 10951126 10.1046/j.1365-201x.2000.00745.x 1:CAS:528:DC%2BD3cXms1yntbs%3D
    • J Bejma P Ramires LL Ji 2000 Free radical generation and oxidative stress with ageing and exercise: Differential effects in the myocardium and liver Acta Physiologica Scandinavica 169 343 351 10951126 10.1046/j.1365-201x.2000.00745.x 1:CAS:528:DC%2BD3cXms1yntbs%3D
    • (2000) Acta Physiologica Scandinavica , vol.169 , pp. 343-351
    • Bejma, J.1    Ramires, P.2    Ji, L.L.3
  • 5
    • 1242272825 scopus 로고    scopus 로고
    • Responses of rat myocardial antioxidant defences and heat shock protein HSP72 induced by 12 and 24-week treadmill training
    • DOI 10.1111/j.0001-6772.2003.01244.x
    • M Morán J Delgado B González R Manso A Megías 2004 Responses of rat myocardial antioxidant defences and heat shock protein HSP72 induced by 12 and 24-week treadmill training Acta Physiologica Scandinavica 180 157 166 14738474 10.1111/j.0001-6772.2003.01244.x (Pubitemid 38241383)
    • (2004) Acta Physiologica Scandinavica , vol.180 , Issue.2 , pp. 157-166
    • Moran, M.1    Delgado, J.2    Gonzalez, B.3    Manso, R.4    Megias, A.5
  • 8
    • 0036398754 scopus 로고    scopus 로고
    • Cardiovascular effects of androgens
    • W Weidemann H Hanke 2002 Cardiovascular effects of androgens Cardiovascular Drug Reviews 20 175 198 12397366 10.1111/j.1527-3466.2002. tb00086.x 1:CAS:528:DC%2BD38XovVWnsrk%3D (Pubitemid 35204767)
    • (2002) Cardiovascular Drug Reviews , vol.20 , Issue.3 , pp. 175-198
    • Weidemann, W.1    Hanke, H.2
  • 11
    • 2942541820 scopus 로고    scopus 로고
    • Effects of androgenic-anabolic steroids in athletes
    • DOI 10.2165/00007256-200434080-00003
    • F Hartgens H Kuipers 2004 Effects of androgenic-anabolic steroids in athletes Sports Medicine 34 513 554 15248788 10.2165/00007256-200434080-00003 (Pubitemid 38981844)
    • (2004) Sports Medicine , vol.34 , Issue.8 , pp. 513-554
    • Hartgens, F.1    Kuipers, H.2
  • 12
    • 77956265177 scopus 로고    scopus 로고
    • Testosterone affects hormone-sensitive lipase (HSL) activity and lipid metabolism in the left ventricle
    • 20691154 10.1016/j.bbrc.2010.07.140 1:CAS:528:DC%2BC3cXhtFamsLfJ
    • J Langfort S Jagsz P Dobrzyn Z Brzezinska B Klapcinska H Galbo J Gorski 2010 Testosterone affects hormone-sensitive lipase (HSL) activity and lipid metabolism in the left ventricle Biochemical and Biophysical Research Communications 399 670 676 20691154 10.1016/j.bbrc.2010.07.140 1:CAS:528:DC%2BC3cXhtFamsLfJ
    • (2010) Biochemical and Biophysical Research Communications , vol.399 , pp. 670-676
    • Langfort, J.1    Jagsz, S.2    Dobrzyn, P.3    Brzezinska, Z.4    Klapcinska, B.5    Galbo, H.6    Gorski, J.7
  • 13
    • 33748752043 scopus 로고    scopus 로고
    • Testosterone is required for delayed cardioprotection and enhanced heat shock protein 70 expression induced by preconditioning
    • DOI 10.1210/en.2006-0297
    • J Liu S Tsang TM Wong 2006 Testosterone is required for delayed cardioprotection and enhanced heat shock protein 70 expression induced by preconditioning Endocrinology 147 4569 4577 16794012 10.1210/en.2006-0297 1:CAS:528:DC%2BD28XhtVSksbzL (Pubitemid 44402162)
    • (2006) Endocrinology , vol.147 , Issue.10 , pp. 4569-4577
    • Liu, J.1    Tsang, S.2    Tak, M.W.3
  • 14
    • 76149093242 scopus 로고    scopus 로고
    • Testosterone administration induces protection against global myocardial ischemia
    • 19862668 10.1055/s-0029-1241843 1:CAS:528:DC%2BC3cXivFCiu7o%3D
    • SE Borst JC Quindry JF Yarrow CF Conover SK Powers 2010 Testosterone administration induces protection against global myocardial ischemia Hormone and Metabolic Research 42 122 129 19862668 10.1055/s-0029-1241843 1:CAS:528:DC%2BC3cXivFCiu7o%3D
    • (2010) Hormone and Metabolic Research , vol.42 , pp. 122-129
    • Borst, S.E.1    Quindry, J.C.2    Yarrow, J.F.3    Conover, C.F.4    Powers, S.K.5
  • 16
    • 45349086665 scopus 로고    scopus 로고
    • Effects of castration and testosterone replacement on the antioxidant defense system in rat left ventricle
    • DOI 10.2170/physiolsci.RP002208
    • B Kłapcińska S Jagsz E Sadowska-Krȩpa J Górski K Kempa J Langfort 2008 Effects of castration and testosterone replacement on the antioxidant defense system in the rat left ventricle Journal of Physiological Sciences 58 173 177 18445310 10.2170/physiolsci.RP002208 (Pubitemid 351846446)
    • (2008) Journal of Physiological Sciences , vol.58 , Issue.3 , pp. 173-177
    • Klapcinska, B.1    Jagsz, S.2    Sadowska-Krepa, E.3    Gorski, J.4    Kempa, K.5    Langfort, J.6
  • 17
    • 43949087882 scopus 로고    scopus 로고
    • Anabolic steroid use: Patterns of use and detection of doping
    • DOI 10.2165/00007256-200838060-00005
    • MR Graham B Davies FM Grace A Kicman JS Baker 2008 Anabolic steroid use. Patterns of use and detection of doping Sports Medicine 38 505 525 18489196 10.2165/00007256-200838060-00005 (Pubitemid 351704855)
    • (2008) Sports Medicine , vol.38 , Issue.6 , pp. 505-525
    • Graham, M.R.1    Davies, B.2    Grace, F.M.3    Kicman, A.4    Baker, J.S.5
  • 18
    • 58749102809 scopus 로고    scopus 로고
    • Long-term psychiatric and medical consequences of anabolic-androgenic steroid abuse: A looming public health concern?
    • 18599224 10.1016/j.drugalcdep.2008.05.004 1:CAS:528:DC%2BD1cXhtVOiu77M
    • G Kanayama JO Hudson HG Pope Jr 2008 Long-term psychiatric and medical consequences of anabolic-androgenic steroid abuse: A looming public health concern? Drug and Alcohol Dependence 98 1 12 18599224 10.1016/j.drugalcdep.2008. 05.004 1:CAS:528:DC%2BD1cXhtVOiu77M
    • (2008) Drug and Alcohol Dependence , vol.98 , pp. 1-12
    • Kanayama, G.1    Hudson, J.O.2    Pope Jr., H.G.3
  • 19
    • 0034121295 scopus 로고    scopus 로고
    • Risk factors associated with anabolic-androgenic steroid use among adolescents
    • MS Bahrke CE Yesalis AN Kopstein JA Stephens 2000 Risk factors associated with anabolic-androgenic steroid use among adolescents Sports Medicine 29 397 405 10870866 10.2165/00007256-200029060-00003 1:STN:280:DC%2BD3cvpvVamtQ%3D%3D (Pubitemid 30392020)
    • (2000) Sports Medicine , vol.29 , Issue.6 , pp. 397-405
    • Bahrke, M.S.1    Yesalis, C.E.2    Kopstein, A.N.3    Stephens, J.A.4
  • 20
    • 77956326235 scopus 로고    scopus 로고
    • Cardiac and metabolic effects of anabolic-androgenic steroid abuse on lipids, blood pressure, left ventricular dimensions, and rhythm
    • 20816133 10.1016/j.amjcard.2010.05.013 1:CAS:528:DC%2BC3cXhtFWqtL7J
    • S Achar A Rostamian SM Narayan 2010 Cardiac and metabolic effects of anabolic-androgenic steroid abuse on lipids, blood pressure, left ventricular dimensions, and rhythm American Journal of Cardiology 106 893 901 20816133 10.1016/j.amjcard.2010.05.013 1:CAS:528:DC%2BC3cXhtFWqtL7J
    • (2010) American Journal of Cardiology , vol.106 , pp. 893-901
    • Achar, S.1    Rostamian, A.2    Narayan, S.M.3
  • 21
    • 78649904984 scopus 로고    scopus 로고
    • Evidence of altered cardiac electrophysiology following prolonged androgenic anabolic steroid use
    • 21038102 10.1007/s12012-010-9090-y 1:CAS:528:DC%2BC3cXhsVCmsb%2FN
    • N Sculthorpe F Grace P Jones B Davies 2010 Evidence of altered cardiac electrophysiology following prolonged androgenic anabolic steroid use Cardiovascular Toxicology 10 239 243 21038102 10.1007/s12012-010-9090-y 1:CAS:528:DC%2BC3cXhsVCmsb%2FN
    • (2010) Cardiovascular Toxicology , vol.10 , pp. 239-243
    • Sculthorpe, N.1    Grace, F.2    Jones, P.3    Davies, B.4
  • 22
    • 0018936424 scopus 로고
    • Sudden death in young athletes
    • B Maron WC Roberts HA McAllister DR Rosing SE Epstein 1980 Sudden death in young athletes Circulation 62 218 229 6446987 1:STN:280:DyaL3c3ksVCksA%3D%3D (Pubitemid 10035639)
    • (1980) Circulation , vol.62 , Issue.2 , pp. 218-229
    • Maron, B.J.1    Roberts, W.C.2    McAllister, H.A.3
  • 23
    • 67249116428 scopus 로고    scopus 로고
    • Heart lesions associated with anabolic steroid abuse: Comparison of post-mortem findings in athletes and norethandrolone-induced lesions in rabbits
    • 19027274 10.1016/j.etp.2008.09.007 1:CAS:528:DC%2BD1MXosVygu7g%3D
    • L Fanton D Belhani F Vaillant A Tabib L Gomez J Descotes L Dehina B Bui-Xuan D Malicier Q Timour 2009 Heart lesions associated with anabolic steroid abuse: Comparison of post-mortem findings in athletes and norethandrolone- induced lesions in rabbits Experimental and Toxicologic Pathology 61 317 323 19027274 10.1016/j.etp.2008.09.007 1:CAS:528:DC%2BD1MXosVygu7g%3D
    • (2009) Experimental and Toxicologic Pathology , vol.61 , pp. 317-323
    • Fanton, L.1    Belhani, D.2    Vaillant, F.3    Tabib, A.4    Gomez, L.5    Descotes, J.6    Dehina, L.7    Bui-Xuan, B.8    Malicier, D.9    Timour, Q.10
  • 24
    • 0035126972 scopus 로고    scopus 로고
    • Anabolic-androgenic steroids induce apoptotic cell death in adult rat ventricular myocytes
    • DOI 10.1002/1097-4652(2001)9999:9999<00::AID-JCP1057>3.0.CO;2-Y
    • M Zaugg NZ Jamali E Lucchinetti W Xu M Alam SA Shafiq MA Siddiqui 2001 Anabolic-androgenic steroids induce apoptotic cell death in adult rat ventricular myocytes Journal of Cellular Physiology 187 90 95 11241353 10.1002/1097-4652(2001)9999:9999<00::AID-JCP1057>3.0.CO;2-Y 1:CAS:528:DC%2BD3MXhs1KqtbY%3D (Pubitemid 32195249)
    • (2001) Journal of Cellular Physiology , vol.187 , Issue.1 , pp. 90-95
    • Zaugg, M.1    Jamali, N.Z.2    Lucchinetti, E.3    Xu, W.4    Alam, M.5    Shafiq, S.A.6    Siddiqui, M.A.Q.7
  • 25
    • 7044250697 scopus 로고    scopus 로고
    • Direct effects of sex steroid hormones on adipose tissues and obesity
    • DOI 10.1111/j.1467-789X.2004.00152.x
    • JS Mayes GH Watson 2004 Direct effects of sex steroid hormones on adipose tissues and obesity Obesity Reviews 5 197 216 15458395 10.1111/j.1467-789X. 2004.00152.x 1:CAS:528:DC%2BD2cXhtVSlt7fM (Pubitemid 39423001)
    • (2004) Obesity Reviews , vol.5 , Issue.4 , pp. 197-216
    • Mayes, J.S.1    Watson, G.H.2
  • 26
    • 0022599496 scopus 로고
    • Concentrations of free testosterone, total testosterone, and androgen binding protein in the peripheral serum of male rats during sexual maturation
    • SJ Nazian 1986 Concentrations of free testosterone, total testosterone, and androgen binding protein in the peripheral serum of male rats during sexual maturation Journal of Andrology 7 49 54 3944019 1:CAS:528:DyaL28Xhs1aitro%3D (Pubitemid 16132309)
    • (1986) Journal of Andrology , vol.7 , Issue.1 , pp. 49-54
    • Nazian, S.J.1
  • 27
    • 0025358959 scopus 로고
    • Superoxide dismutase undergoes proteolysis and fragmentation following oxidative modification and inactivation
    • DC Salo RE Pacifici SW Lin C Giulivi KJA Davies 1990 Superoxide dismutase undergoes proteolysis and fragmentation following oxidative modification and inactivation Journal of Biological Chemistry 265 11919 11927 2195028 1:CAS:528:DyaK3cXlt1Orsro%3D (Pubitemid 120013349)
    • (1990) Journal of Biological Chemistry , vol.265 , Issue.20 , pp. 11919-11927
    • Salo, D.C.1    Pacifici, R.E.2    Lin, S.W.3    Giulivi, C.4    Davies, K.J.A.5
  • 28
    • 0020490598 scopus 로고
    • Superoxide radical inhibits catalase
    • 6279612 1:CAS:528:DyaL38XktVakt7g%3D
    • Y Kono I Fridovich 1982 Superoxide radical inhibits catalase Journal of Biological Chemistry 257 5751 5754 6279612 1:CAS:528:DyaL38XktVakt7g%3D
    • (1982) Journal of Biological Chemistry , vol.257 , pp. 5751-5754
    • Kono, Y.1    Fridovich, I.2
  • 29
    • 0033535974 scopus 로고    scopus 로고
    • Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis
    • R von Harsdorf PF Li R Dietz 1999 Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis Circulation 99 2934 2941 (Pubitemid 29258983)
    • (1999) Circulation , vol.99 , Issue.22 , pp. 2934-2941
    • Von Harsdorf, R.1    Li, P.-F.2    Dietz, R.3
  • 30
    • 4644248309 scopus 로고    scopus 로고
    • Apoptotic adaptations from exercise training in skeletal and cardiac muscles
    • DOI 10.1096/fj.03-1291fje
    • PM Siu RW Bryner JK Martyn SE Alway 2004 Apoptotic adaptations from exercise training in skeletal and cardiac muscles FASEB Journal 18 1150 1152 15132982 1:CAS:528:DC%2BD2cXlslKkt74%3D (Pubitemid 39561553)
    • (2004) FASEB Journal , vol.18 , Issue.10 , pp. 1150-1152
    • Siu, P.M.1    Bryner, R.W.2    Marty, J.K.3    Alway, S.E.4
  • 31
    • 33845548577 scopus 로고    scopus 로고
    • The effect of endurance training on regional serotonin metabolism in the brain during early stage of detraining period in the female rat
    • DOI 10.1007/s10571-006-9065-5, Proceedings of the 5th International Symposium on Experimental and Clinical Neurobiology, High Tatras, Slovakia, September 2005
    • J Langfort E Barańczuk D Pawlak M Chalimoniuk N Lukacova J Marsala J Górski 2006 The effect of endurance training on regional serotonin metabolism in the brain during early stage of detraining period in the female rat Cellular and Molecular Neurobiology 26 1327 1342 16897368 10.1007/s10571-006-9065-5 1:CAS:528:DC%2BD28Xht1yktbzF (Pubitemid 44924050)
    • (2006) Cellular and Molecular Neurobiology , vol.26 , Issue.7-8 , pp. 1327-1342
    • Langfort, J.1    Baranczuk, E.2    Pawlak, D.3    Chalimoniuk, M.4    Lukacova, N.5    Marsala, J.6    Gorski, J.7
  • 34
    • 37849049214 scopus 로고    scopus 로고
    • Exercise-induced cardioprotection against myocardial ischemia-reperfusion injury
    • 18191755 10.1016/j.freeradbiomed.2007.02.006 1:CAS:528: DC%2BD1cXlvVyguw%3D%3D
    • SK Powers JC Quindry AN Kavazis 2008 Exercise-induced cardioprotection against myocardial ischemia-reperfusion injury Free Radical Biology and Medicine 44 193 201 18191755 10.1016/j.freeradbiomed.2007.02.006 1:CAS:528: DC%2BD1cXlvVyguw%3D%3D
    • (2008) Free Radical Biology and Medicine , vol.44 , pp. 193-201
    • Powers, S.K.1    Quindry, J.C.2    Kavazis, A.N.3
  • 35
    • 0037375942 scopus 로고    scopus 로고
    • Exercise, antioxidants, and HSP72: Protection against myocardial ischemia/reperfusion
    • DOI 10.1016/S0891-5849(02)01431-4
    • KL Hamilton JL Staib T Phillips A Hess SL Lennon SK Powers 2003 Exercise, antioxidants, and HSP72: Protection against myocardial ischemia/reperfusion Free Radical Biology and Medicine 34 800 809 12654467 10.1016/S0891-5849(02) 01431-4 1:CAS:528:DC%2BD3sXitlajsLc%3D (Pubitemid 36316063)
    • (2003) Free Radical Biology and Medicine , vol.34 , Issue.7 , pp. 800-809
    • Hamilton, K.L.1    Staib, J.L.2    Phillips, T.3    Hess, A.4    Lennon, S.L.5    Powers, S.K.6
  • 38
    • 0038375011 scopus 로고    scopus 로고
    • γ-Tocopherol, but not α-tocopherol, decreases proinflammatory eicosanoids and inflammation damage in rats
    • DOI 10.1096/fj.02-0877com
    • Q Jiang BN Ames 2003 γ-Tocopherol, but not α-tocopherol, decreases proinflammatory eicosanoids and inflammation damage in rats FASEB Journal 17 816 822 12724340 10.1096/fj.02-0877com 1:CAS:528:DC%2BD3sXjsFCltro%3D (Pubitemid 36538656)
    • (2003) FASEB Journal , vol.17 , Issue.8 , pp. 816-822
    • Jiang, Q.1    Ames, B.N.2
  • 39
    • 0030020030 scopus 로고    scopus 로고
    • Gamma, but not alpha, tocopherol levels in serum are reduced in coronary heart disease patients
    • M Ohrvall G Sundlof B Vessby 1996 Gamma, but not alpha, tocopherol levels in serum are reduced in coronary heart disease patients Journal of Internal Medicine 239 111 117 8568478 10.1046/j.1365-2796.1996.410753000.x 1:STN:280:DyaK287mtlCisw%3D%3D (Pubitemid 26043146)
    • (1996) Journal of Internal Medicine , vol.239 , Issue.2 , pp. 111-117
    • Ohrvall, M.1    Sundlof, C.2    Vessby, B.3
  • 40
    • 0034773256 scopus 로고    scopus 로고
    • Antioxidant mobilization in response to oxidative stress: A dynamic environmental-nutritional interaction
    • DOI 10.1016/S0899-9007(01)00646-3, PII S0899900701006463
    • NM Elsayed 2001 Antioxidant mobilization in response to oxidative stress: A dynamic environmental-nutritional interaction Nutrition 17 828 834 11684389 10.1016/S0899-9007(01)00646-3 1:CAS:528:DC%2BD3MXnvFKjtb8%3D (Pubitemid 33001649)
    • (2001) Nutrition , vol.17 , Issue.10 , pp. 828-834
    • Elsayed, N.M.1
  • 41
    • 0033547737 scopus 로고    scopus 로고
    • Mobilization of antioxidant vitamin pools and hemodynamic function after myocardial infarction
    • VP Palace MF Hill F Farahmand PK Singal 1999 Mobilization of antioxidant vitamin pools and hemodynamic function after myocardial infarction Circulation 99 121 126 9884388 1:CAS:528:DyaK1MXnsFCrsw%3D%3D (Pubitemid 29035966)
    • (1999) Circulation , vol.99 , Issue.1 , pp. 121-126
    • Palace, V.P.1    Hill, M.F.2    Farahmand, F.3    Singal, P.K.4


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