Neuroplastin-65 and a mimetic peptide derived from its homophilic binding site modulate neuritogenesis and neuronal plasticity

Journal of Neurochemistry

Volumn 117, Issue 6, 2011, Pages 984-994

  Owczarek, Sylwia ^a,b   Soroka, Vladislav ^a,c   Kiryushko, Darya ^a   Larsen, Marianne Hald ^d   Yuan, Qionglan ^a   Sandi, Carmen ^d   Berezin, Vladimir ^a   Bock, Elisabeth ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b BISPEBJERG HOSPITAL   (Denmark)

^c Enkam Pharmaceuticals AS   (Denmark)

^d EPFL   (Switzerland)

Author keywords

cell adhesion molecule; neurite outgrowth; peptide mimetic

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM ION; ENPLASTIN; FIBROBLAST GROWTH FACTOR RECEPTOR; GLYCOPROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; NEUROPLASTIN 65; PEPTIDOMIMETIC AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; BRAIN NERVE CELL; CALCIUM CELL LEVEL; CELL STRAIN HEK293; COGNITION; CONTROLLED STUDY; CYTOPLASM; DEPTH PERCEPTION; ENZYME ACTIVATION; GROWTH INHIBITION; HIPPOCAMPUS; IN VITRO STUDY; LEARNING; MAZE TEST; NERVE CELL DIFFERENTIATION; NERVE CELL PLASTICITY; NERVE FIBER GROWTH; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN MOTIF; RAT; SIGNAL TRANSDUCTION;

ANIMALS; BINDING SITES; CALCIUM; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CELLS, CULTURED; CEREBELLUM; ENZYME ACTIVATION; HIPPOCAMPUS; MAZE LEARNING; MEMBRANE GLYCOPROTEINS; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR MIMICRY; NEURITES; NEURONAL PLASTICITY; NEURONS; PEPTIDES; PROTEIN BINDING; PROTEIN ISOFORMS; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; RECEPTORS, FIBROBLAST GROWTH FACTOR; RECOMBINANT PROTEINS;

RATTUS;

EID: 79958013914     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07269.x     Document Type: Article

References (26)

1. Appel F., Holm J., Conscience J. F., von Bohlen und Halbach F., Faissner A., James P., and, Schachner M., (1995) Identification of the border between fibronectin type III homologous repeats 2 and 3 of the neural cell adhesion molecule L1 as a neurite outgrowth promoting and signal transducing domain. J. Neurobiol. 28, 297-312.
2. Archer F. R., Doherty P., Collins D., and, Bolsover S. R., (1999) CAMs and FGF cause a local submembrane calcium signal promoting axon outgrowth without a rise in bulk calcium concentration. Eur. J. Neurosci. 11, 3565-3573. (Pubitemid 29484253)
3. Bukalo O., Fentrop N., Lee A. Y., Salmen B., Law J. W., Wotjak C. T., Schweizer M., Dityatev A., and, Schachner M., (2004) Conditional ablation of the neural cell adhesion molecule reduces precision of spatial learning, long-term potentiation, and depression in the CA1 subfield of mouse hippocampus. J. Neurosci. 24, 1565-1577. (Pubitemid 38240951)
4. Cambon K., Hansen S. M., Venero C., Herrero A. I., Skibo G., Berezin V., Bock E., and, Sandi C., (2004) A synthetic neural cell adhesion molecule mimetic peptide promotes synaptogenesis, enhances presynaptic function, and facilitates memory consolidation. J. Neurosci. 24, 4197-4204. (Pubitemid 38620795)
5. Ditlevsen D. K., Berezin V., and, Bock E., (2007) Signalling pathways underlying neural cell adhesion molecule-mediated survival of dopaminergic neurons. Eur. J. Neurosci. 25, 1678-1684. (Pubitemid 46550009)
6. Durand G. M., Kovalchuk Y., and, Konnerth A., (1996) Long-term potentiation and functional synapse induction in developing hippocampus. Nature 381, 71-75. (Pubitemid 26130004)
7. Empson R. M., Buckby L. E., Kraus M., Bates K. J., Crompton M. R., Gundelfinger E. D., and, Beesley P. W., (2006) The cell adhesion molecule neuroplastin-65 inhibits hippocampal long-term potentiation via a mitogen-activated protein kinase p38-dependent reduction in surface expression of GluR1-containing glutamate receptors. J. Neurochem. 99, 850-860. (Pubitemid 44583444)
8. Eshhar N., Petralia R. S., Winters C. A., Niedzielski A. S., and, Wenthold R. J., (1993) The segregation and expression of glutamate receptor subunits in cultured hippocampal neurons. Neuroscience 57, 943-964. (Pubitemid 23354998)
9. Garcia-Maya M., Anderson A. A., Kendal C. E., Kenny A. V., Edwards-Ingram L. C., Holladay A., and, Saffell J. L., (2006) Ligand concentration is a driver of divergent signaling and pleiotropic cellular responses to FGF. J. Cell. Physiol. 206, 386-393. (Pubitemid 43062807)
10. Groc L., Gustafsson B., and, Hanse E., (2006) AMPA signalling in nascent glutamatergic synapses: there and not there!. Trends Neurosci. 29, 132-139.
11. Hansen S. M., Berezin V., and, Bock E., (2008) Signaling mechanisms of neurite outgrowth induced by the cell adhesion molecules NCAM and N-cadherin. Cell. Mol. Life Sci. 65, 3809-3821.
12. Isaac J. T., Nicoll R. A., and, Malenka R. C., (1995) Evidence for silent synapses: implications for the expression of LTP. Neuron 15, 427-434.
13. Juliano R. L., (2002) Signal transduction by cell adhesion receptors and the cytoskeleton: functions of integrins, cadherins, selectins, and immunoglobulin-superfamily members. Annu. Rev. Pharmacol. Toxicol. 42, 283-323. (Pubitemid 34160528)
14. 2+ homeostasis. Mol. Biol. Cell 17, 2278-2286. (Pubitemid 44011743)
15. Langnaese K., Beesley P. W., and, Gundelfinger E. D., (1997) Synaptic membrane glycoproteins gp65 and gp55 are new members of the immunoglobulin superfamily. J. Biol. Chem. 272, 821-827. (Pubitemid 27034569)
16. Langnaese K., Mummery R., Gundelfinger E. D., and, Beesley P. W., (1998) Immunoglobulin superfamily members gp65 and gp55: tissue distribution of glycoforms. FEBS Lett. 429, 284-288. (Pubitemid 28300376)
17. Morris R. G., Garrud P., Rawlins J. N., and, O'Keefe J., (1982) Place navigation impaired in rats with hippocampal lesions. Nature 297, 681-683. (Pubitemid 12096189)
18. Owczarek S., Kiryushko D., Larsen M. H., Kastrup J. S., Gajhede M., Sandi C., Berezin V., Bock E., and, Soroka V., (2010) Neuroplastin-55 binds to and signals through the fibroblast growth factor receptor. FASEB J. 24, 1139-1150.
19. Pettersen E. F., Goddard T. D., Huang C. C., Couch G. S., Greenblatt D. M., Meng E. C., and, Ferrin T. E., (2004) UCSF Chimera-a visualization system for exploratory research and analysis. J. Comput. Chem. 25, 1605-1612.
20. Raghava G. P. S., (2002) APSSP2: A combination method for protein secondary structure prediction based on neural network and example based learning. CASP5 A-132.
21. Reisel D., Bannerman D. M., Deacon R. M., Sprengel R., Seeburg P. H., and, Rawlins J. N., (2005) GluR-A-dependent synaptic plasticity is required for the temporal encoding of nonspatial information. Behav. Neurosci. 119, 1298-1306. (Pubitemid 41598742)
22. Ronn L. C., Doherty P., Holm A., Berezin V., and, Bock E., (2000) Neurite outgrowth induced by a synthetic peptide ligand of neural cell adhesion molecule requires fibroblast growth factor receptor activation. J. Neurochem. 75, 665-671. (Pubitemid 30485447)
23. Ronn L. C., Dissing S., Holm A., Berezin V., and, Bock E., (2002) Increased intracellular calcium is required for neurite outgrowth induced by a synthetic peptide ligand of NCAM. FEBS Lett. 518, 60-66. (Pubitemid 34454964)
24. Smalla K. H., Matthies H., Langnase K., et al. (2000) The synaptic glycoprotein neuroplastin is involved in long-term potentiation at hippocampal CA1 synapses. Proc. Natl Acad. Sci. USA 97, 4327-4332. (Pubitemid 30226132)
25. Soroka V., Kolkova K., Kastrup J. S., et al. (2003) Structure and interactions of NCAM Ig1-2-3 suggest a novel zipper mechanism for homophilic adhesion. Structure 11, 1291-1301. (Pubitemid 37214890)
26. Williams E. J., Mittal B., Walsh F. S., and, Doherty P., (1995) A Ca2+/calmodulin kinase inhibitor, KN-62, inhibits neurite outgrowth stimulated by CAMs and FGF. Mol. Cell. Neurosci. 6, 69-79.