Structural basis for drug and substrate specificity exhibited by FIV encoding a chimeric FIV/HIV protease

Acta Crystallographica Section D: Biological Crystallography

Volumn 67, Issue 6, 2011, Pages 540-548

  Lin, Ying Chuan ^a   Perryman, Alexander L ^a   Olson, Arthur J ^a   Torbett, Bruce E ^a   Elder, John H ^a   Stout, C David ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

chimeric FIV HIV protease; darunavir; feline immunodeficiency virus; lopinavir

Indexed keywords

ASPARTIC PROTEINASE; FIV PROTEASE; HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE; RECOMBINANT PROTEIN;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; ENZYMOLOGY; FELINE IMMUNODEFICIENCY VIRUS; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ASPARTIC ACID ENDOPEPTIDASES; CRYSTALLOGRAPHY, X-RAY; HIV; HIV PROTEASE; IMMUNODEFICIENCY VIRUS, FELINE; MODELS, MOLECULAR; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

FELINE IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS;

EID: 79958011495     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S0907444911011681     Document Type: Article

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