Role of γδ T cells in antibody production and recovery from SFV demyelinating disease

Journal of Neuroimmunology

Volumn 235, Issue 1-2, 2011, Pages 18-26

  Safavi, Farinaz ^a   Feliberti, Jason P ^a   Raine, Cedric S ^b   Mokhtarian, Foroozan ^a  

^a SUNY Downstate Medical Center   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Antibody; Brain mononuclear cells; E2 Th peptide2; Immunization; Inflammation; Knock out; Remyelination; Semliki Forest Virus; T cell receptor ; Wild type

Indexed keywords

EPITOPE; PEPTIDE; VIRUS ANTIBODY; VIRUS PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ANTIBODY PRODUCTION; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DEMYELINATING DISEASE; DEMYELINATION; DISEASE SEVERITY; FEMALE; GAMMA DELTA T LYMPHOCYTE; IMMUNOPATHOGENESIS; IMMUNOREACTIVITY; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; REMYELINIZATION; RNA VIRUS INFECTION; SEMLIKI FOREST ALPHAVIRUS; WILD TYPE;

ALPHAVIRUS INFECTIONS; ANIMALS; ANTIBODIES, VIRAL; DEMYELINATING DISEASES; EPITOPES, T-LYMPHOCYTE; FEMALE; MICE; MICE, CONGENIC; MICE, INBRED C57BL; MICE, KNOCKOUT; MULTIPLE SCLEROSIS; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; RECOVERY OF FUNCTION; SEMLIKI FOREST VIRUS; T-LYMPHOCYTE SUBSETS;

EID: 79958002369     PISSN: 01655728     EISSN: 18728421     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2011.02.013     Document Type: Article

References (56)

1. Allan W., Carding S.R., Eichelberger M., Doherty P.C. Analyzing the distribution of cells expressing mRNA for T cell receptor gamma and delta chains in a virus-induced inflammatory process. Cell. Immunol. 1992, 143:55-65.
2. Atkins G.J., Sheahan B.J., Liljestrom P. The molecular pathogenesis of Semliki Forest virus: a model virus made useful?. J. Gen. Virol. 1999, 80:2287-2297.
3. Barnett M.H., Prineas J.W. Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion. Ann. Neurol. 2004, 55:458-468.
4. Blink S.E., Miller S.D. The contribution of gammadelta T cells to the pathogenesis of EAE and MS. Curr. Mol. Med. 2009, 9(1):15-22.
5. Boere W.A., Benaissa-Trouw B.J., Harmsen M., Kraaijeveld C.A., Snippe H. Neutralizing and non-neutralizing monoclonal antibodies to the E2 glycoprotein of Semliki Forest virus can protect mice from lethal encephalitis. J. Gen.Virol. 1983, 64:1405-1408.
6. Carding S.R., Allan W., Kyes S., Hayday A., Bottomly K., Doherty P.C. Late dominance of the inflammatory process in murine influenza by gamma/delta+ T cells. J. Exp. Med. 1990, 172:1225-1231.
7. Chien Y.H., Konigshofer Y. Antigen recognition by gammadelta T cells. Immunol. Rev. 2007, 215:46-58.
8. Ciric B., Van Keulena V., Paz Soldan M., Rodriguez M., Pease L.R. Antibody-mediated remyelination operates through mechanism independent of immunomodulation. J. Neuroimmunol. 2004, 146:153-161.
9. Clark R.B., Lingenheld E.G. Adoptively transferred EAE in gamma delta T cell-knockout mice. J. Autoimmun. 1998, 11:105-110.
10. Dandekar A.A., Perlman S. Virus-induced demyelination in nude mice is mediated by gamma delta T cells. Am. J. Pathol. 2002, 161:1255-1263.
11. Fazakerley J.K. Semliki forest virus infection of laboratory mice: a model to study the pathogenesis of viral encephalitis. Arch. Virol. 2004, 179-190. Suppl.
12. Fazakerley J.K., Amor S., Nash A.A. Animal model systems of MS. Molecular Biology of Multiple Sclerosis 1997, 255-273. John Wiley & Sons, Ltd., New York, N.Y. W.C. Russell (Ed.).
13. Fernández I.M., Harmsen M., Benaissa-Trouw B.J., Stuij I., Puyk W., Meloen R.H., Snippe H., Kraaijeveld C.A. Epitope polarity and adjuvants influence the fine specificity of the humoral response against Semliki Forest virus specific peptide vaccines. Vaccine 1998, 16:1531-1536.
14. Frohman E.M., Racke M.K., Raine C.S. Multiple sclerosis-the plaque and its pathogenesis. N. Engl. J. Med. 2006, 354:942-955.
15. Hou S., Katz J.M., Doherty P.C., Carding S.R. Extent of gamma delta T cell involvement in the pneumonia caused by Sendai virus. Cell. Immunol. 1992, 143:183-193.
16. Huber S.A., Graveline D., Born W.K., O'Brien R.L. Cytokine production by Vgamma(+)-T cell subsets is an important factor determining CD4(+)-Th-cell phenotype and susceptibility of BALB/c mice to coxsackievirus B3-induced myocarditis. J. Virol. 2001, 75:5860-5869.
17. Itohara S., Mombaerts P., Lafaille J., Iacomini J., Nelson A., Clarke A.R., Hooper M.L., Farr A., Tonegawa S. T cell receptor delta gene mutant mice: independent generation of alpha beta T cells and programmed rearrangements of gamma delta TCR genes. Cell 1993, 72:337-348.
18. Kobayashi Y., Kawai K., Ito K., Honda H., Sobue G., Yoshikai Y. Aggravation of murine experimental allergic encephalomyelitis by administration of T cell receptor gammadelta-specific antibody. J. Neuroimmunol. 1997, 73:169-174.
19. Lanier L.L., Federspiel N.A., Ruitenberg J.J., Phillips J.H., Allison J.P., Littman D., Weiss A. The T cell antigen receptor complex expressed on normal peripheral blood CD4-, CD8-T lymphocytes. A CD3-associated disulfide-linked gamma chain heterodimer. J. Exp. Med. 1987, 165:1076-1094.
20. Ludwin S.K., Raine C.S. The neuropathology of multiple sclerosis. Multiple Sclerosis: a Comprehensive Text 2008, 151-177. Saunders/Elsevier Publishers, Edinburgh. C.S. Raine, H.F. McFarland, R. Hohlfeld (Eds.).
21. Mahy B.W.J. Virology a Practical Approach 1985, Oxford University Press, Walton Street, Oxford.
22. Mateo Paz Soldan M., Rodriguez M. Heterogeneity of pathogenesis in multiple sclerosis: implications for promotions of remyelination. J. Infect. Dis. 2002, 186:S248-S253.
23. Matsumoto Y., Kohyama K., Aikawa Y., Shin T., Kawazoe Y., Suzuki Y., Tanuma N. Role of natural killer cells and TCR gamma delta T cells in acute autoimmune encephalomyelitis. Eur. J. Immunol. 1998, 28:1681-1688.
24. Miller D.J., Bright J.J., Sriram S., Rodriguez M. Successful treatment of established relapsing experimental autoimmune encephalomyelitis in mice with a monoclonal natural autoantibody. J. Neuroimmunol. 1997, 75:204-209.
25. Mitsunaga Y., Ciric B., Van K.V., Warrington A.E., Paz S.M., Bieber A.J., Rodriguez M., Pease L.R. Direct evidence that a human antibody derived from patient serum can promote myelin repair in a mouse model of chronic-progressive demyelinating disease. FASEB J. 2002, 16:1325-1327.
26. Mokhtarian F., Swoveland P. Predisposition to EAE induction in resistant mice by prior infection with Semliki Forest virus. J. Immunol. 1987, 138:3264-3268.
27. Mokhtarian F., Shi Y., Zhu P.F., Grob D. Immune responses, and autoimmune outcome, during virus infection of the central nervous system. Cell. Immunol. 1994, 157:195-210.
28. Mokhtarian F., Zhang Z., Shi Y., Gonzales E., Sobel R.A. Molecular mimicry between a viral peptide and a myelin oligodendrocyte glycoprotein peptide induces autoimmune demyelinating disease in mice. J. Neuroimmunol. 1999, 95:43-54.
29. Mokhtarian F., Huan C.M., Roman C., Raine C.S. Semliki Forest virus-induced demyelination and remyelination-involvement of B cells and anti-myelin antibodies. J. Neuroimmunol. 2003, 137:19-31.
30. Pao W., Wen L., Smith A.L., Gulbranson-Judge A., Zheng B., Kelsoe G., MacLennan I.C., Owen M.J., Hayday A.C. Gamma delta T cell help of B cells is induced by repeated parasitic infection, in the absence of other T cells. Curr. Biol. 1996, 6:1317-1325.
31. Pardoll D.M., Fowlkes B.J., Bluestone J.A., Kruisbeek A., Maloy W.L., Coligan J.E., Schwartz R.H. Differential expression of two distinct T cell receptors during thymocyte development. Nature 1987, 326:79-81.
32. Paz Soldán M.M., Warrington A.E., Bieber A.J., Ciric B., Van Keulen V., Pease L.R., Rodriguez M. Remyelination-promoting antibodies activate distinct Ca2+ influx pathways in astrocytes and oligodendrocytes: relationship to the mechanism of myelin repair. Mol. Cell. Neurosci. 2003, 22:14-24.
33. Peterman G.M., Spencer C., Sperling A.I., Bluestone J.A. Role of gamma delta T cells in murine collagen-induced arthritis. J. Immunol. 1993, 151:6546-6558.
34. Raine C.S. Biology of disease. The analysis of autoimmune demyelination: its impact upon multiple sclerosis. Lab. Invest. 1984, 50:608-635.
35. Raine C.S., Scheinberg L., Waltz T.M. Multiple sclerosis: oligodendrocyte survival and prolifration in an active, established lesion. Lab. Invest. 1981, 45:534-546.
36. Raine C.S., Mokhtarian F., McFarlin D.E. Adoptively transferred chronic relapsing experimental autoimmune encephalomyelitis in the mouse. Neuropathologic analysis. Lab. Invest. 1984, 51:534-546.
37. Rajan A.J., Gao Y.L., Raine C.S., Brosnan C.F. A pathogenic role for gamma delta T cells in relapsing-remitting experimental allergic encephalomyelitis in the SJL mouse. J. Immunol. 1996, 157:941-949.
38. Rajan A.J., Klein J.D., Brosnon C.F. The effect of gammadelta T cell depletion on cytokine gene expression in experimental allergic encephalomyelitis. J. Immunol. 1998, 160:5955-5962.
39. Rajan A.J., Asensio V.C., Campbell I.L., Brosnon C.F. Experimental autoimmune encephalomyelitis on the SJL mouse: effect of gamma delta T cell depletion on chemokine and chemokine receptor expression in the central nervous system. J. Immunol. 2000, 164:2120-2130.
40. Rodriguez M., Miller D.J., Lennon V.A. Immunoglobulins reactive with myelin basic protein promote CNS remyelination. Neurology 1996, 46:538-545.
41. Rodriguez M., Warrington A.E., Pease L.R. Invited article: human natural autoantibodies in the treatment of neurologic disease. Neurology 2009, 72:1269-1276.
42. Sciammas R., Johnson R.M., Sperling A.I., Brady W., Linsley P.S., Spear P.G., Fitch F.W., Bluestone J.A. Unique antigen recognition by a herpesvirus-pecific TCR-gamma delta cell. J. Immunol. 1994, 152:5392-5397.
43. Selin L.K., Santolucito P.A., Pinto A.K., Szomolanyi-Tsuda E., Welsh R.M. Innate immunity to viruses: control of vaccinia virus infection by gamma delta T cells. J. Immunol. 2001, 166:6784-6794.
44. Selmaj K., Brosnan C.F., Raine C.S. Colocalization of lymphocytes bearing gamma delta T cell receptor and heat shock protein hsp65+ oligodendrocytes in multiple sclerosis. Proc. Natl. Acad. Sci. 1991, 88:6452-6456.
45. Smith-Norowitz T.A., Sobel R.A., Mokhtarian F. B cells and antibodies in the pathogenesis of myelin injury in Semliki Forest Virus encephalomyelitis. Cell. Immunol. 2000, 200:27-35.
46. Snijders A., Benaissa-Trouw B.J., Oosting J.D., Snippe H., Kraaijeveld C.A. Identification of a DTH-inducing T cell epitope on the E2 membrane protein of Semliki Forest virus. Cell. Immunol. 1989, 123:23-35.
47. Snijders A., Benaissa-Trouw B.J., Oosterlaken T.A., Puijk W.C., Posthumus W.P., Meloen R.H., Boere W.A., Oosting J.D., Kraaijeveld C.A., Snippe H. Identification of linear epitopes on Semliki Forest virus E2 membrane protein and their effectiveness as a synthetic peptide vaccine. J. Gen. Virol. 1991, 72:557-565.
48. Snijders A., Benaissa-Trouw B.J., Snippe H., Kraaijeveld C.A. Immunogenicity and vaccine efficacy of synthetic peptides containing Semliki Forest virus B and T cell epitopes. J. Gen. Virol. 1992, 73:2267-2272.
49. Soilu-Hänninen M., Erälinna J.P., Hukkanen V., Röyttä M., Salmi A.A., Salonen R. Semliki Forest virus infects mouse brain endothelial cells and causes blood-brain barrier damage. J. Virol. 1994, 68:6291-6298.
50. Subak-Sharpe I., Dyson H., Fazakerley J.K. In vivo depletion of CD8+ T cells prevents lesions of demyelination in Semliki Forest virus infection. J. Virol. 1993, 67:7629-7633.
51. Teitelbaum D., Aharoni R., Sela M., Arnon R. Cross-reactions and specificities of monoclonal antibodies against myelin basic protein and against the synthetic copolymer-1. Proc. Natl. Acad. Sci. 1991, 88:9525-9532.
52. Tsunoda I., Fujinami R.S. Neuropathogenesis of Theiler's MurineEncephalomyelitis Virus Infection, An Animal Model for Multiple Sclerosis. J. Neuroimmune Pharmacol. 2010, 5:355-369.
53. Ure D.R., Rodriguez M. Polyreactive antibodies to glatiramer acetate promote myelin repair in murine model of demyelinating disease. FASEB J. 2002, express article. Published online June 7, 2002. 10.1096/fj.01-1023fje.
54. Wang T., Scully E., Yin Z., Kim J.H., Wang S., Yan J., Mamula M., Anderson J.F., Craft J., Fikrig E. IFN-gamma-producing gamma delta T cells help control murine West Nile virus infection. J. Immunol. 2003, 171:2524-2531.
55. Warrington A.E., Asakura K., Bieber A.J., Ciric B., Van K.V., Kaveri S.V., Kyle R.A., Pease L.R., Rodriguez M. Human monoclonal antibodies reactive to oligodendrocytes promote remyelination in a model of multiple sclerosis. Proc. Natl. Acad. Sci. 2000, 97:6820-6825.
56. Zheng B., Marinova E., Han J., Tan T.H., Han S. Cutting edge: gamma delta T cells provide help to B cells with altered clonotypes and are capable of inducing Ig gene hypermutation. J. Immunol. 2003, 171:4979-4983.