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Volumn 12, Issue 6, 2011, Pages 594-598

Utility of measuring serum concentrations of anti-TNF agents and anti-drug antibodies in inflammatory bowel disease

Author keywords

Adalimumab; Antibodies; Immunogenicity; Infliximab; Through levels; Tumor necrosis factor alpha

Indexed keywords

ADALIMUMAB; CERTOLIZUMAB PEGOL; DRUG ANTIBODY; ETANERCEPT; IMMUNOMODULATING AGENT; INFLIXIMAB; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR INHIBITOR;

EID: 79957956645     PISSN: 13892002     EISSN: 18755453     Source Type: Journal    
DOI: 10.2174/138920011795713689     Document Type: Article
Times cited : (20)

References (44)
  • 1
    • 0036105388 scopus 로고    scopus 로고
    • The genetic jigsaw of inflammatory bowel disease
    • Watts, D. A.; Satsangi, J. The genetic jigsaw of inflammatory bowel disease. Gut, 2002, 50 Suppl 3, III31-6. (Pubitemid 34407454)
    • (2002) Gut , vol.50 , Issue.SUPPL. 3
    • Watts, D.A.1    Satsangi, J.2
  • 3
    • 0029900295 scopus 로고    scopus 로고
    • The tumor necrosis factor ligand and receptor families
    • DOI 10.1056/NEJM199606273342607
    • Bazzoni, F.; Beutler, B. The tumor necrosis factor ligand and receptor families. N. Engl. J. Med., 1996, 334(26), 1717-25. (Pubitemid 26193625)
    • (1996) New England Journal of Medicine , vol.334 , Issue.26 , pp. 1717-1725
    • Bazzoni, F.1    Beutler, B.2
  • 4
    • 33644625163 scopus 로고    scopus 로고
    • Demonstration of specific antibodies against infliximab induced during treatment of a patient with ankylosing spondylitis
    • Aybay, C.; Ozel, S. Demonstration of specific antibodies against infliximab induced during treatment of a patient with ankylosing spondylitis. Rheumatol. Int., 2006, 26(5), 473-80.
    • (2006) Rheumatol. Int. , vol.26 , Issue.5 , pp. 473-480
    • Aybay, C.1    Ozel, S.2
  • 6
    • 77957928601 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha monoclonal antibodies in the treatment of inflammatory bowel disease: Clinical practice pharmacology
    • Lee, T. W.; Fedorak, R. N. Tumor necrosis factor-alpha monoclonal antibodies in the treatment of inflammatory bowel disease: clinical practice pharmacology. Gastroenterol. Clin. North Am., 2010, 39(3), 543-57.
    • (2010) Gastroenterol. Clin. North Am. , vol.39 , Issue.3 , pp. 543-557
    • Lee, T.W.1    Fedorak, R.N.2
  • 7
    • 77955489317 scopus 로고    scopus 로고
    • Anti-TNF therapy, from rationale to standard of care: What lessons has it taught us?
    • Feldmann, M.; Maini, R. N. Anti-TNF therapy, from rationale to standard of care: what lessons has it taught us? J.Immunol., 2010, 185(2), 791-4.
    • (2010) J.Immunol. , vol.185 , Issue.2 , pp. 791-794
    • Feldmann, M.1    Maini, R.N.2
  • 8
    • 0034005581 scopus 로고    scopus 로고
    • Role of cytokines in the pathogenesis of inflammatory bowel disease
    • DOI 10.1146/annurev.med.51.1.289
    • Papadakis, K. A.; Targan, S. R. Role of cytokines in the pathogenesis of inflammatory bowel disease. Annu. Rev. Med., 2000, 51, 289-98. (Pubitemid 30216038)
    • (2000) Annual Review of Medicine , vol.51 , pp. 289-298
    • Papadakis, K.A.1    Targan, S.R.2
  • 9
    • 14944382276 scopus 로고    scopus 로고
    • Infliximab induces potent anti-inflammatory responses by outside-to-inside signals through transmembrane TNF-α
    • DOI 10.1053/j.gastro.2004.11.060
    • Mitoma, H.; Horiuchi, T.; Hatta, N.; Tsukamoto, H.; Harashima, S.; Kikuchi, Y.; Otsuka, J.; Okamura, S.; Fujita, S.; Harada, M. Infliximab induces potent anti-inflammatory responses by outsideto- inside signals through transmembrane TNF-alpha. Gastroenterology, 2005, 128(2), 376-92. (Pubitemid 40431090)
    • (2005) Gastroenterology , vol.128 , Issue.2 , pp. 376-392
    • Mitoma, H.1    Horiuchi, T.2    Hatta, N.3    Tsukamoto, H.4    Harashima, S.-I.5    Kikuchi, Y.6    Otsuka, J.7    Okamura, S.8    Fujita, S.9    Harada, M.10
  • 10
    • 0029004771 scopus 로고
    • Chimeric anti-TNF-alpha monoclonal antibody cA2 binds recombinant transmembrane TNF-alpha and activates immune effector functions
    • Scallon, B. J.; Moore, M. A.; Trinh, H.; Knight, D. M.; Ghrayeb, J. Chimeric anti-TNF-alpha monoclonal antibody cA2 binds recombinant transmembrane TNF-alpha and activates immune effector functions. Cytokine, 1995, 7(3), 251-9.
    • (1995) Cytokine , vol.7 , Issue.3 , pp. 251-259
    • Scallon, B.J.1    Moore, M.A.2    Trinh, H.3    Knight, D.M.4    Ghrayeb, J.5
  • 11
    • 1542369183 scopus 로고    scopus 로고
    • Optimizing anti-tumor necrosis factor strategies in inflammatory bowel disease
    • Sandborn, W. J. Optimizing anti-tumor necrosis factor strategies in inflammatory bowel disease. Curr. Gastroenterol. Rep., 2003, 5(6), 501-5. (Pubitemid 38915050)
    • (2003) Current Gastroenterology Reports , vol.5 , Issue.6 , pp. 501-505
    • Sandborn, W.J.1
  • 17
    • 62049083383 scopus 로고    scopus 로고
    • Loss of response and requirement of infliximab dose intensification in Crohn's disease: A review
    • Gisbert, J. P.; Panes, J. Loss of response and requirement of infliximab dose intensification in Crohn's disease: a review. Am. J. Gastroenterol., 2009, 104(3), 760-7.
    • (2009) Am. J. Gastroenterol. , vol.104 , Issue.3 , pp. 760-767
    • Gisbert, J.P.1    Panes, J.2
  • 18
    • 73449104613 scopus 로고    scopus 로고
    • Predicting the response to infliximab from trough serum levels
    • Rutgeerts, P.; Vermeire, S.; Van Assche, G. Predicting the response to infliximab from trough serum levels. Gut, 2010, 59(1), 7-8.
    • (2010) Gut , vol.59 , Issue.1 , pp. 7-8
    • Rutgeerts, P.1    Vermeire, S.2    Van Assche, G.3
  • 19
    • 17044418491 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of TNF antagonists: How do they differ?
    • Nestorov, I. Clinical pharmacokinetics of TNF antagonists: how do they differ? Semin. Arthritis Rheum., 2005, 34(5 Suppl1), 12-8.
    • (2005) Semin. Arthritis Rheum. , vol.34 , Issue.5 SUPPL.1 , pp. 12-18
    • Nestorov, I.1
  • 20
    • 33749432435 scopus 로고    scopus 로고
    • Association of Trough Serum Infliximab to Clinical Outcome After Scheduled Maintenance Treatment for Crohn's Disease
    • DOI 10.1016/j.cgh.2006.06.025, PII S154235650600677X
    • Maser, E. A.; Villela, R.; Silverberg, M. S.; Greenberg, G. R. Association of trough serum infliximab to clinical outcome after scheduled maintenance treatment for Crohn's disease. Clin. Gastroenterol. Hepatol., 2006, 4(10), 1248-54. (Pubitemid 44512213)
    • (2006) Clinical Gastroenterology and Hepatology , vol.4 , Issue.10 , pp. 1248-1254
    • Maser, E.A.1    Villela, R.2    Silverberg, M.S.3    Greenberg, G.R.4
  • 21
    • 73449088039 scopus 로고    scopus 로고
    • Trough serum infliximab: A predictive factor of clinical outcome for infliximab treatment in acute ulcerative colitis
    • Seow, C. H.; Newman, A.; Irwin, S. P.; Steinhart, A. H.; Silverberg, M. S.; Greenberg, G. R. Trough serum infliximab: a predictive factor of clinical outcome for infliximab treatment in acute ulcerative colitis. Gut, 2010, 59(1), 49-54.
    • (2010) Gut , vol.59 , Issue.1 , pp. 49-54
    • Seow, C.H.1    Newman, A.2    Irwin, S.P.3    Steinhart, A.H.4    Silverberg, M.S.5    Greenberg, G.R.6
  • 22
    • 26644433889 scopus 로고    scopus 로고
    • Infliximab induction and maintenance therapy for moderate-to-severe psoriasis: A phase III, multicentre, double-blind trial
    • DOI 10.1016/S0140-6736(05)67566-6, PII S0140673605675666
    • Reich, K.; Nestle, F. O.; Papp, K.; Ortonne, J. P.; Evans, R.; Guzzo, C.; Li, S.; Dooley, L. T.; Griffiths, C. E. Infliximab induction and maintenance therapy for moderate-to-severe psoriasis: a phase III, multicentre, double-blind trial. Lancet, 2005, 366(9494), 1367-74. (Pubitemid 41443403)
    • (2005) Lancet , vol.366 , Issue.9494 , pp. 1367-1374
    • Reich, K.1    Nestle, F.O.2    Papp, K.3    Ortonne, J.-P.4    Evans, R.5    Guzzo, C.6    Li, S.7    Dooley, L.T.8    Griffiths, C.E.M.9
  • 23
    • 0036269445 scopus 로고    scopus 로고
    • The relationship of serum infliximab concentrations to clinical improvement in rheumatoid arthritis: Results from ATTRACT, a multicenter, randomized, double-blind, placebo-controlled trial
    • DOI 10.1002/art.10302
    • St Clair, E. W.; Wagner, C. L.; Fasanmade, A. A.; Wang, B.; Schaible, T.; Kavanaugh, A.; Keystone, E. C. The relationship of serum infliximab concentrations to clinical improvement in rheumatoid arthritis: results from ATTRACT, a multicenter, randomized, double-blind, placebo-controlled trial. Arthritis Rheum., 2002, 46(6), 1451-9. (Pubitemid 34620190)
    • (2002) Arthritis and Rheumatism , vol.46 , Issue.6 , pp. 1451-1459
    • Stclair, E.W.1    Wagner, C.L.2    Fasanmade, A.A.3    Wang, B.4    Schaible, T.5    Kavanaugh, A.6    Keystone, E.C.7
  • 27
    • 77951974444 scopus 로고    scopus 로고
    • Clinical utility of measuring infliximab and human anti-chimeric antibody concentrations in patients with inflammatory bowel disease
    • Afif, W.; Loftus, E. V., Jr.; Faubion, W. A.; Kane, S. V.; Bruining, D. H.; Hanson, K. A.; Sandborn, W. J. Clinical utility of measuring infliximab and human anti-chimeric antibody concentrations in patients with inflammatory bowel disease. Am. J. Gastroenterol., 2010, 105(5), 1133-9.
    • (2010) Am. J. Gastroenterol. , vol.105 , Issue.5 , pp. 1133-1139
    • Afif, W.1    Loftus Jr., E.V.2    Faubion, W.A.3    Kane, S.V.4    Bruining, D.H.5    Hanson, K.A.6    Sandborn, W.J.7
  • 28
    • 3042579454 scopus 로고    scopus 로고
    • Incidence and importance of antibody responses to infliximab after maintenance or episodic treatment in Crohn's disease
    • DOI 10.1016/S1542-3565(04)00238-1, PII S1542356504002381
    • Hanauer, S. B.; Wagner, C. L.; Bala, M.; Mayer, L.; Travers, S.; Diamond, R. H.; Olson, A.; Bao, W.; Rutgeerts, P. Incidence and importance of antibody responses to infliximab after maintenance or episodic treatment in Crohn's disease. Clin. Gastroenterol. Hepatol., 2004, 2(7), 542-53. (Pubitemid 38834038)
    • (2004) Clinical Gastroenterology and Hepatology , vol.2 , Issue.7 , pp. 542-553
    • Hanauer, S.B.1    Wagner, C.L.2    Bala, M.3    Mayer, L.4    Travers, S.5    Diamond, R.H.6    Olson, A.7    Bao, W.8    Rutgeerts, P.9
  • 29
    • 70449725246 scopus 로고    scopus 로고
    • Formation of antibodies against infliximab and adalimumab strongly correlates with functional drug levels and clinical responses in rheumatoid arthritis
    • Radstake, T. R.; Svenson, M.; Eijsbouts, A. M.; van den Hoogen, F. H.; Enevold, C.; van Riel, P. L.; Bendtzen, K. Formation of antibodies against infliximab and adalimumab strongly correlates with functional drug levels and clinical responses in rheumatoid arthritis. Ann. Rheum. Dis., 2009, 68(11), 1739-45.
    • (2009) Ann. Rheum. Dis. , vol.68 , Issue.11 , pp. 1739-1745
    • Radstake, T.R.1    Svenson, M.2    Eijsbouts, A.M.3    Van Den Hoogen, F.H.4    Enevold, C.5    Van Riel, P.L.6    Bendtzen, K.7
  • 30
    • 29444445950 scopus 로고    scopus 로고
    • Clinical and biological consequences of immunization to infliximab in pediatric Crohn's disease
    • DOI 10.1016/j.clim.2005.07.010, PII S1521661605002585
    • Candon, S.; Mosca, A.; Ruemmele, F.; Goulet, O.; Chatenoud, L.; Cezard, J. P. Clinical and biological consequences of immunizationto infliximab in pediatric Crohn's disease. Clin. Immunol., 2006, 118(1), 11-9. (Pubitemid 43012041)
    • (2006) Clinical Immunology , vol.118 , Issue.1 , pp. 11-19
    • Candon, S.1    Mosca, A.2    Ruemmele, F.3    Goulet, O.4    Chatenoud, L.5    Cezard, J.-P.6
  • 31
    • 70349512283 scopus 로고    scopus 로고
    • Incidence and clinical significance of immunogenicity to infliximab in Crohn's disease: A critical systematic review
    • Cassinotti, A.; Travis, S. Incidence and clinical significance of immunogenicity to infliximab in Crohn's disease: a critical systematic review. Inflamm. Bowel Dis., 2009, 15(8), 1264-75.
    • (2009) Inflamm. Bowel Dis. , vol.15 , Issue.8 , pp. 1264-1275
    • Cassinotti, A.1    Travis, S.2
  • 32
    • 0037379792 scopus 로고    scopus 로고
    • Intravenous hydrocortisone premedication reduces antibodies to infliximab in Crohn's disease: A randomized controlled trial
    • DOI 10.1053/gast.2003.50145
    • Farrell, R. J.; Alsahli, M.; Jeen, Y. T.; Falchuk, K. R.; Peppercorn, M. A.; Michetti, P. Intravenous hydrocortisone premedication reduces antibodies to infliximab in Crohn's disease: a randomized controlled trial. Gastroenterology, 2003, 124(4), 917-24. (Pubitemid 36389794)
    • (2003) Gastroenterology , vol.124 , Issue.4 , pp. 917-924
    • Farrell, R.J.1    Alsahli, M.2    Jeen, Y.-T.3    Falchuk, K.R.4    Peppercorn, M.A.5    Michetti, P.6
  • 34
    • 44649090092 scopus 로고    scopus 로고
    • Withdrawal of Immunosuppression in Crohn's Disease Treated With Scheduled Infliximab Maintenance: A Randomized Trial
    • DOI 10.1053/j.gastro.2008.03.004, PII S0016508508004356
    • Van Assche, G.; Magdelaine-Beuzelin, C.; D'Haens, G.; Baert, F.; Noman, M.; Vermeire, S.; Ternant, D.; Watier, H.; Paintaud, G.; Rutgeerts, P. Withdrawal of immunosuppression in Crohn's disease treated with scheduled infliximab maintenance: a randomized trial. Gastroenterology, 2008, 134(7), 1861-8. (Pubitemid 351790744)
    • (2008) Gastroenterology , vol.134 , Issue.7 , pp. 1861-1868
    • Van Assche, G.1    Magdelaine-Beuzelin, C.2    D'Haens, G.3    Baert, F.4    Noman, M.5    Vermeire, S.6    Ternant, D.7    Watier, H.8    Paintaud, G.9    Rutgeerts, P.10
  • 38
    • 33845660797 scopus 로고    scopus 로고
    • Individualized monitoring of drug bioavailability and immunogenicity in rheumatoid arthritis patients treated with the tumor necrosis factor α inhibitor infliximab
    • DOI 10.1002/art.22214
    • Bendtzen, K.; Geborek, P.; Svenson, M.; Larsson, L.; Kapetanovic, M. C.; Saxne, T. Individualized monitoring of drug bioavailability and immunogenicity in rheumatoid arthritis patients treated with the tumor necrosis factor alpha inhibitor infliximab. Arthritis Rheum., 2006, 54(12), 3782-9. (Pubitemid 44955878)
    • (2006) Arthritis and Rheumatism , vol.54 , Issue.12 , pp. 3782-3789
    • Bendtzen, K.1    Geborek, P.2    Svenson, M.3    Larsson, L.4    Kapetanovic, M.C.5    Saxne, T.6
  • 39
    • 70350645060 scopus 로고    scopus 로고
    • Individual medicine in inflammatory bowel disease: Monitoring bioavailability, pharmacokinetics and immunogenicity of anti-tumour necrosis factor-alpha antibodies
    • Bendtzen, K.; Ainsworth, M.; Steenholdt, C.; Thomsen, O. O.; Brynskov, J. Individual medicine in inflammatory bowel disease: monitoring bioavailability, pharmacokinetics and immunogenicity of anti-tumour necrosis factor-alpha antibodies. Scand. J. Gastroenterol., 2009, 44(7), 774-81.
    • (2009) Scand. J. Gastroenterol. , vol.44 , Issue.7 , pp. 774-781
    • Bendtzen, K.1    Ainsworth, M.2    Steenholdt, C.3    Thomsen, O.O.4    Brynskov, J.5
  • 40
    • 36448985258 scopus 로고    scopus 로고
    • Monitoring patients treated with anti-TNF-α biopharmaceuticals: Assessing serum infliximab and anti-infliximab antibodies
    • DOI 10.1093/rheumatology/kem261
    • Svenson, M.; Geborek, P.; Saxne, T.; Bendtzen, K. Monitoring patients treated with anti-TNF-alpha biopharmaceuticals: assessing serum infliximab and anti-infliximab antibodies. Rheumatology (Oxford), 2007, 46(12), 1828-34. (Pubitemid 350168300)
    • (2007) Rheumatology , vol.46 , Issue.12 , pp. 1828-1834
    • Svenson, M.1    Geborek, P.2    Saxne, T.3    Bendtzen, K.4
  • 42
    • 22944444890 scopus 로고    scopus 로고
    • Monoclonal antibodies, immunogenicity, and associated infusion reactions
    • Cheifetz, A.; Mayer, L. Monoclonal antibodies, immunogenicity, and associated infusion reactions. Mt. Sinai. J. Med., 2005, 72(4), 250-6. (Pubitemid 41052052)
    • (2005) Mount Sinai Journal of Medicine , vol.72 , Issue.4 , pp. 250-256
    • Cheifetz, A.1    Mayer, L.2
  • 43
    • 79957951168 scopus 로고    scopus 로고
    • Measurement of human anti- chimeric antibodies (haca) and infliximab levels in patient serum using a novel homogeneous assay
    • Wang S.L.; Ohrmund L.; Singh S. Measurement of Human Anti- Chimeric Antibodies (Haca) and Infliximab Levels in Patient Serum Using a Novel Homogeneous Assay. Gastroenterology, 2010, 138(5), S-684-5.
    • (2010) Gastroenterology , vol.138 , Issue.5
    • Wang, S.L.1    Ohrmund, L.2    Singh, S.3


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