Progressive multifocal leukoencephalopathy (PML) development is associated with mutations in JC virus capsid protein VP1 that change its receptor specificity

Journal of Infectious Diseases

Volumn 204, Issue 1, 2011, Pages 103-114

  Gorelik, Leonid ^a   Reid, Carl ^a   Testa, Manuela ^b   Brickelmaier, Margot ^a   Bossolasco, Simona ^b   Pazzi, Annamaria ^b   Bestetti, Arabella ^b   Carmillo, Paul ^a   Wilson, Ewa ^a   McAuliffe, Michele ^a   Tonkin, Christopher ^a   Carulli, John P ^a   Lugovskoy, Alexey ^a   Lazzarin, Adriano ^b   Sunyaev, Shamil ^c   Simon, Kenneth ^a   Cinque, Paola ^b  

^a BIOGEN   (United States)

^b SAN RAFFAELE HOSPITAL   (Italy)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GANGLIOSIDE; PROTEIN VP1; SIALIC ACID; SIALIDASE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CEREBROSPINAL FLUID ANALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME SPECIFICITY; FEMALE; GLIA CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; JC VIRUS; MALE; NONHODGKIN LYMPHOMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; SYSTEMIC LUPUS ERYTHEMATOSUS; URINALYSIS; VIRAL GENETICS; VIRUS HEMAGGLUTINATION; VIRUS MUTATION; VIRUS PARTICLE;

ADULT; CAPSID PROTEINS; CEREBROSPINAL FLUID; FEMALE; HUMAN DEVELOPMENT; HUMANS; JC VIRUS; LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL; MALE; MIDDLE AGED; MUTATION, MISSENSE; NUCLEAR PROTEINS; RECEPTORS, VIRUS; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS; VIRAL TROPISM; VIRUS ATTACHMENT;

EID: 79957947385     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jir198     Document Type: Article

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