Association of the Skn7 and Yap1 transcription factors in the saccharomyces cerevisiae oxidative stress response

Eukaryotic Cell

Volumn 10, Issue 6, 2011, Pages 761-769

  Mulford, K E ^b   Fassler, J S ^a  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; PEPTIDE FRAGMENT; SACCHAROMYCES CEREVISIAE PROTEIN; SKN7 PROTEIN, S CEREVISIAE; TRANSCRIPTION FACTOR; YAP1 PROTEIN, S CEREVISIAE;

ARTICLE; DNA RESPONSIVE ELEMENT; FUNGAL GENE; GENE INACTIVATION; GENETICS; IMMUNOPRECIPITATION; METABOLISM; MISSENSE MUTATION; OXIDATIVE STRESS; PHENOTYPE; PHYSIOLOGY; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; REPORTER GENE; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION INITIATION;

DNA-BINDING PROTEINS; GENE KNOCKOUT TECHNIQUES; GENES, FUNGAL; GENES, REPORTER; IMMUNOPRECIPITATION; MUTATION, MISSENSE; OXIDATIVE STRESS; PEPTIDE FRAGMENTS; PHENOTYPE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RESPONSE ELEMENTS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION;

SACCHAROMYCES CEREVISIAE;

EID: 79957931614     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.00328-10     Document Type: Article

References (50)

1. Ausubel, F. M., et al. 1989. Current protocols in molecular biology, vol. 1. John Wiley & Sons, Inc., New York, NY.
2. Brown, J. L., H. Bussey, and R. C. Stewart. 1994. Yeast Skn7p functions in a eukaryotic two-component regulatory pathway. EMBO J. 13:5186-5194.
3. Brown, J. L., S. North, and H. Bussey. 1993. SKN7, a yeast multicopy suppressor of a mutation affecting cell wall beta-glucan assembly, encodes a product with domains homologous to prokaryotic two-component regulators and to heat shock transcription factors. J. Bacteriol. 175:6908-6915.
4. Charizanis, C., H. Juhnke, B. Krems, and K. D. Entian. 1999. The oxidative stress response mediated via Pos9/Skn7 is negatively regulated by the Ras/PKA pathway in Saccharomyces cerevisiae. Mol. Gen. Genet. 261:740-752.
5. Coleman, S. T., E. A. Epping, S. M. Steggerda, and W. S. Moye-Rowley. 1999. Yap1p activates gene transcription in an oxidant-specific fashion. Mol. Cell. Biol. 19:8302-8313.
6. Coleman, S. T., E. Tseng, and W. S. Moye-Rowley. 1997. Saccharomyces cerevisiae basic region-leucine zipper protein regulatory networks converge at the ATR1 structural gene. J. Biol. Chem. 272:23224-23230.
7. De Antoni, A., and D. Gallwitz. 2000. A novel multi-purpose cassette for repeated integrative epitope tagging of genes in Saccharomyces cerevisiae. Gene 246:179-185.
8. Dean, S. 2004. Achieving specificity in yeast stress responses. Ph.D. thesis. University of Iowa, Iowa City, IA.
9. Delaunay, A., A. D. Isnard, and M. B. Toledano. 2000. H2O2 sensing through oxidation of the Yap1 transcription factor. EMBO J. 19:5157-5166.
10. Delaunay, A., D. Pflieger, M. B. Barrault, J. Vinh, and M. B. Toledano. 2002. A thiol peroxidase is an H2O2 receptor and redox-transducer in gene activation. Cell 111:471-481.
11. Fernandes, L., C. Rodrigues-Pousada, and K. Struhl. 1997. Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions. Mol. Cell. Biol. 17:6982-6993.
12. Ghaemmaghami, S., et al. 2003. Global analysis of protein expression in yeast. Nature 425:737-741.
13. Gulshan, K., S. A. Rovinsky, S. T. Coleman, and W. S. Moye-Rowley. 2005. Oxidant-specific folding of Yap1p regulates both transcriptional activation and nuclear localization. J. Biol. Chem. 280:40524-40533.
14. He, X. J., and J. S. Fassler. 2005. Identification of novel Yap1p and Skn7p binding sites involved in the oxidative stress response of Saccharomyces cerevisiae. Mol. Microbiol. 58:1454-1467.
15. He, X. J., K. E. Mulford, and J. S. Fassler. 2009. Oxidative stress function of the Saccharomyces cerevisiae Skn7 receiver domain. Eukaryot. Cell 8:768-778.
16. Hughes, T. R., et al. 2000. Functional discovery via a compendium of expression profiles. Cell 102:109-126.
17. James, P., J. Halladay, and E. A. Craig. 1996. Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics 144:1425-1436.
18. Ketela, T., J. L. Brown, R. C. Stewart, and H. Bussey. 1998. Yeast Skn7p activity is modulated by the Sln1p-Ypd1p osmosensor and contributes to regulation of the HOG pathway. Mol. Gen. Genet. 259:372-378.
19. Krems, B., C. Charizanis, and K. D. Entian. 1996. The response regulatorlike protein Pos9/Skn7 of Saccharomyces cerevisiae is involved in oxidative stress resistance. Curr. Genet. 29:327-334.
20. Kuge, S., et al. 2001. Regulation of the yeast Yap1p nuclear export signal is mediated by redox signal-induced reversible disulfide bond formation. Mol. Cell. Biol. 21:6139-6150.
21. Kuge, S., and N. Jones. 1994. YAP1-dependent activation of TRX2 is essential for the response of Saccharomyces cerevisiae to oxidative stress by hydroperoxides. EMBO J. 13:655-664.
22. Kuge, S., N. Jones, and A. Nomoto. 1997. Regulation of yAP-1 nuclear localization in response to oxidative stress. EMBO J. 16:1710-1720.
23. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
24. Lee, J., et al. 1999. Yap1 and Skn7 control two specialized oxidative stress response regulons in yeast. J. Biol. Chem. 274:16040-16046.
25. Li, S., et al. 1998. The yeast histidine protein kinase, Sln1p, mediates phosphotransfer to two response regulators, Ssk1p and Skn7p. EMBO J. 17:6952-6962.
26. Li, S., et al. 2002. The eukaryotic two-component histidine kinase Sln1p regulates OCH1 via the transcription factor, Skn7p. Mol. Biol. Cell 13:412-424.
27. Lu, J. M., R. J. Deschenes, and J. S. Fassler. 2004. Role for the Ran binding protein, Mog1p, in Saccharomyces cerevisiae SLN1-SKN7 signal transduction. Eukaryot. Cell 3:1544-1556.
28. Lu, J. M., R. J. Deschenes, and J. S. Fassler. 2003. Saccharomyces cerevisiae histidine phosphotransferase Ypd1p shuttles between the nucleus and cytoplasm for SLN1-dependent phosphorylation of Ssk1p and Skn7p. Eukaryot. Cell 2:1304-1314.
29. Miller, J. H. 1972. Experiments in molecular genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
30. Morgan, B. A., et al. 1997. The Skn7 response regulator controls gene expression in the oxidative stress response of the budding yeast Saccharomyces cerevisiae. EMBO J. 16:1035-1044.
31. Moye-Rowley, W. S., K. D. Harshman, and C. S. Parker. 1989. Yeast YAP1 encodes a novel form of the jun family of transcriptional activator proteins. Genes Dev. 3:283-292.
32. Okazaki, S., T. Tachibana, A. Naganuma, N. Mano, and S. Kuge. 2007. Multistep disulfide bond formation in Yap1 is required for sensing and transduction of H2O2 stress signal. Mol. Cell 27:675-688.
33. Page, N., J. Sheraton, J. L. Brown, R. C. Stewart, and H. Bussey. 1996. Identification of ASK10 as a multicopy activator of Skn7p-dependent transcription of a HIS3 reporter gene. Yeast 12:267-272.
34. Raitt, D. C., et al. 2000. The Skn7 response regulator of Saccharomyces cerevisiae interacts with Hsf1 in vivo and is required for the induction of heat shock genes by oxidative stress. Mol. Biol. Cell 11:2335-2347.
35. Ross, S. J., V. J. Findlay, P. Malakasi, and B. A. Morgan. 2000. Thioredoxin peroxidase is required for the transcriptional response to oxidative stress in budding yeast. Mol. Biol. Cell 11:2631-2642.
36. Shankarnarayan, S., C. L. Malone, R. J. Deschenes, and J. S. Fassler. 2008. Modulation of yeast Sln1 kinase activity by the CCW12 cell wall protein. J. Biol. Chem. 283:1962-1973.
37. Sherman, F., G. R. Fink, and J. B. Hicks. 1986. Methods in yeast genetics, p. 163-167. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
38. Sikorski, R. S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122:19-27.
39. Takeuchi, T., K. Miyahara, D. Hirata, and T. Miyakawa. 1997. Mutational analysis of Yap1 protein, an AP-1-like transcriptional activator of Saccharomyces cerevisiae. FEBS Lett. 416:339-343.
40. Tao, W., R. J. Deschenes, and J. S. Fassler. 1999. Intracellular glycerol levels modulate the activity of Sln1p, a Saccharomyces cerevisiae two-component regulator. J. Biol. Chem. 274:360-367.
41. Tsuzi, D., K. Maeta, Y. Takatsume, S. Izawa, and Y. Inoue. 2004. Regulation of the yeast phospholipid hydroperoxide glutathione peroxidase GPX2 by oxidative stress is mediated by Yap1 and Skn7. FEBS Lett. 565:148-154.
42. Veal, E. A., S. J. Ross, P. Malakasi, E. Peacock, and B. A. Morgan. 2003. Ybp1 is required for the hydrogen peroxide-induced oxidation of the Yap1 transcription factor. J. Biol. Chem. 278:30896-30904.
43. Wemmie, J. A., S. M. Steggerda, and W. S. Moye-Rowley. 1997. The Saccharomyces cerevisiae AP-1 protein discriminates between oxidative stress elicited by the oxidants H2O2 and diamide. J. Biol. Chem. 272:7908-7914.
44. Wemmie, J. A., A. L. Wu, K. D. Harshman, C. S. Parker, and W. S. Moye-Rowley. 1994. Transcriptional activation mediated by the yeast AP-1 protein is required for normal cadmium tolerance. J. Biol. Chem. 269:14690-14697.
45. Williams, K. E., and M. S. Cyert. 2001. The eukaryotic response regulator Skn7p regulates calcineurin signaling through stabilization of Crz1p. EMBO J. 20:3473-3483.
46. Wood, M. J., E. C. Andrade, and G. Storz. 2003. The redox domain of the Yap1p transcription factor contains two disulfide bonds. Biochemistry 42: 11982-11991.
47. Wood, M. J., G. Storz, and N. Tjandra. 2004. Structural basis for redox regulation of Yap1 transcription factor localization. Nature 430:917-921.
48. Wu, A., et al. 1993. Yeast bZip proteins mediate pleiotropic drug and metal resistance. J. Biol. Chem. 268:18850-18858.
49. Wu, A. L., and W. S. Moye-Rowley. 1994. GSH1, which encodes gamma glutamylcysteine synthetase, is a target gene for yAP-1 transcriptional regulation. Mol. Cell. Biol. 14:5832-5839.
50. Yan, C., L. H. Lee, and L. I. Davis. 1998. Crm1p mediates regulated nuclear export of a yeast AP-1-like transcription factor. EMBO J. 17:7416-7429.