Bone marrow-derived microglia in pilocytic astrocytoma

Frontiers in Bioscience - Elite

Volumn 3 E, Issue 1, 2011, Pages 371-379

  Alshakweer, Wafa ^a   Alwelaie, Yazeed ^a   Mankung, Aaron M ^a   Graeber, Manuel B ^a,b  

^a KING FAHAD MEDICAL CITY   (Saudi Arabia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Bone marrow; Brain macrophages; Cell based therapies; Glioma immunology; Macrophage polarization; Perivascular cells

Indexed keywords

ALPHA 2 MACROGLOBULIN; CD163 ANTIGEN; CD68 ANTIGEN; COLONY STIMULATING FACTOR 1; HEME OXYGENASE 1; INTERCELLULAR ADHESION MOLECULE 1; CD34 ANTIGEN; CELL SURFACE RECEPTOR; DIFFERENTIATION ANTIGEN; LEUKOCYTE ANTIGEN;

ARTICLE; BONE MARROW DERIVED MICROGLIA; COMPUTER MODEL; CONTROLLED STUDY; GLIOMA; HUMAN; HUMAN TISSUE; IMMUNOPHENOTYPING; IMMUNOREACTIVITY; MACROPHAGE; MICROGLIA; PHENOTYPE; PILOCYTIC ASTROCYTOMA; TUMOR ASSOCIATED LEUKOCYTE; VASCULARIZATION; ASTROCYTOMA; BONE MARROW CELL; CELL DIFFERENTIATION; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; METABOLISM; MICROARRAY ANALYSIS;

ANTIGENS, CD; ANTIGENS, CD34; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; ASTROCYTOMA; BONE MARROW CELLS; CELL DIFFERENTIATION; HUMANS; IMMUNOHISTOCHEMISTRY; MACROPHAGES; MICROARRAY ANALYSIS; MICROGLIA; RECEPTORS, CELL SURFACE;

EID: 79957875395     PISSN: 19450494     EISSN: 19450508     Source Type: Journal    
DOI: None     Document Type: Article

References (71)

1. D. T. Jones, K. Ichimura, L. Liu, D. M. Pearson, K. Plant and V. P. Collins: Genomic analysis of pilocytic astrocytomas at 0.97 Mb resolution shows an increasing tendency toward chromosomal copy number change with age. Journal of Neuropathology and Experimental Neurology, 65, 1049-58 (2006) (Pubitemid 44684662)
2. H. Huang, A. Hara, T. Homma, Y. Yonekawa and H. Ohgaki: Altered expression of immune defense genes in pilocytic astrocytomas. Journal of Neuropathology and Experimental Neurology, 64, 891-901 (2005) (Pubitemid 41434672)
3. F. Geranmayeh, B. W. Scheithauer, C. Spitzer, F. B. Meyer, A. C. Svensson-Engwall and M. B. Graeber: Microglia in gemistocytic astrocytomas. Neurosurgery, 60, 159-66; discussion 166 (2007) (Pubitemid 46102965)
4. R. Klein and W. Roggendorf: Increased microglia proliferation separates pilocytic astrocytomas from diffuse astrocytomas: a double labeling study. Acta Neuropathologica, 101, 245-8 (2001) (Pubitemid 32219758)
5. C. T. Tran, P. Wolz, R. Egensperger, S. Koesel, Y. Imai, K. Bise, S. Kohsaka, P. Mehraein and M. B. Graeber: Differential expression of MHC class II molecules by microglia and neoplastic astroglia: relevance for the escape of astrocytoma cells from immune surveillance. Neuropathology and Applied Neurobiology, 24, 293-301 (1998) (Pubitemid 28389126)
6. A. Sasaki, H. Yamaguchi, Y. Horikoshi, G. Tanaka and Y. Nakazato: Expression of glucose transporter 5 by microglia in human gliomas. Neuropathology and Applied Neurobiology, 30, 447-55 (2004) (Pubitemid 39423032)
7. S. K. Moestrup and H. J. Møller: CD163: a regulated hemoglobin scavenger receptor with a role in the antiinflammatory response. Annals of Medicine, 36, 347-54 (2004) (Pubitemid 39233102)
8. S. K. Lau, P. G. Chu and L. M. Weiss: CD163: a specific marker of macrophages in paraffin-embedded tissue samples. American Journal of Clinical Pathology, 122, 794-801 (2004) (Pubitemid 39434761)
9. Y. Komohara, K. Ohnishi, J. Kuratsu and M. Takeya: Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas. Journal of Pathology, 216, 15-24 (2008)
10. C. Werno, H. Menrad, A. Weigert, N. Dehne, S. Goerdt, K. Schledzewski, J. Kzhyshkowska and B. Brüne: Knockout of Hif-1alpha in tumor-associated macrophages enhances M2 polarization and attenuates their pro-angiogenic responses. Carcinogenesis (2010)
11. K. Kawamura, Y. Komohara, K. Takaishi, H. Katabuchi and M. Takeya: Detection of M2 macrophages and colonystimulating factor 1 expression in serous and mucinous ovarian epithelial tumors. Pathology International, 59, 300-5 (2009)
12. A. Sica, T. Schioppa, A. Mantovani and P. Allavena: Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy. European Journal of Cancer 42, 717-27 (2006)
13. F. O. Martinez, L. Helming and S. Gordon: Alternative activation of macrophages: an immunologic functional perspective. Annual Review of Immunology, 27, 451-83 (2009)
14. B. O. Fabriek, E. S. Van Haastert, I. Galea, M. M. Polfliet, E. D. Döpp, M. M. Van Den Heuvel, T. K. Van Den Berg, C. J. De Groot, P. Van der Valk and C. D. Dijkstra: CD163-positive perivascular macrophages in the human CNS express molecules for antigen recognition and presentation. Glia, 51, 297-305 (2005) (Pubitemid 41532105)
15. M. B. Graeber, W. J. Streit and G. W. Kreutzberg: Identity of ED2-positive perivascular cells in rat brain. Journal of Neuroscience Research, 22, 103-6 (1989) (Pubitemid 19067258)
16. B. O. Fabriek, M. M. Polfliet, R. P. Vloet, R. C. Van der Schors, A. J. Ligtenberg, L. K. Weaver, C. Geest, K. Matsuno, S. K. Moestrup, C. D. Dijkstra and T. K. Van Den Berg: The macrophage CD163 surface glycoprotein is an erythroblast adhesion receptor. Blood, 109, 5223-9 (2007) (Pubitemid 46890540)
17. E. S. Roberts, E. Masliah and H. S. Fox: CD163 identifies a unique population of ramified microglia in HIV encephalitis (HIVE). Journal of Neuropathology and Experimental Neurology, 63, 1255-64 (2004) (Pubitemid 39603397)
18. A. Flügel, M. Bradl, G. W. Kreutzberg and M. B. Graeber: Transformation of donor-derived bone marrow precursors into host microglia during autoimmune CNS inflammation and during the retrograde response to axotomy. Journal of Neuroscience Research, 66, 74-82 (2001) (Pubitemid 32937060)
19. B. W. Scheithauer, C. Hawkins, T. Tihan, S. R. Van Den Berg and P. C. Burger: Pilocytic astrocytoma. In: WHO Classification of Tumours of the Central Nervous System. Ed D. N. Louis, H. Ohgaki, O. D. Wiestler & W. K. Cavenee. IARC, Lyon (2007)
20. L. B. Moran and M. B. Graeber: Towards a pathway definition of Parkinson's disease: a complex disorder with links to cancer, diabetes and inflammation. Neurogenetics, 9, 1-13 (2008)
21. M. B. Graeber, W. J. Streit, D. Büringer, D. L. Sparks and G. W. Kreutzberg: Ultrastructural location of major histocompatibility complex (MHC) class II positive perivascular cells in histologically normal human brain. Journal of Neuropathology and Experimental Neurology, 51, 303-11 (1992)
22. Y. Tanaka, A. Sasaki, S. Ishiuchi and Y. Nakazato: Diversity of glial cell components in pilocytic astrocytoma. Neuropathology, 28, 399-407 (2008) (Pubitemid 351798979)
23. H. J. Møller, H. Aerts, H. Grønbaek, N. A. Peterslund, P. Hyltoft Petersen, N. Hornung, L. Rejnmark, E. Jabbarpour and S. K. Moestrup: Soluble CD163: a marker molecule for monocyte/macrophage activity in disease. Scandinavian Journal of Clinical and Laboratory Investigation Supplementum, 237, 29-33 (2002)
24. I. Shabo, H. Olsson, X. F. Sun and J. Svanvik: Expression of the macrophage antigen CD163 in rectal cancer cells is associated with early local recurrence and reduced survival time. International Journal of Cancer, 125, 1826-31 (2009)
25. I. Shabo, O. Stål, H. Olsson, S. Doré and J. Svanvik: Breast cancer expression of CD163, a macrophage scavenger receptor, is related to early distant recurrence and reduced patient survival. International Journal of Cancer, 123, 780-6 (2008) (Pubitemid 352032402)
26. M. Ritter, C. Buechler, T. Langmann and G. Schmitz: Genomic organization and chromosomal localization of the human CD163 (M130) gene: a member of the scavenger receptor cysteine-rich superfamily. Biochemical and Biophysical Research Communications, 260, 466-74 (1999) (Pubitemid 29352086)
27. M. Ritter, C. Buechler, T. Langmann, E. Orsó, J. Klucken and G. Schmitz: The scavenger receptor CD163: regulation, promoter structure and genomic organization. Pathobiology, 67, 257-61 (1999) (Pubitemid 30135918)
28. M. J. Nielsen, H. J. Moller and S. K. Moestrup: Hemoglobin and heme scavenger receptors. Antioxidants & Redox Signaling, 12, 261-7 (2010)
29. G. Onofre, M. Kolácková, K. Jankovicová and J. Krejsek: Scavenger receptor CD163 and its biological functions. Acta Medica, 52, 57-61 (2009)
30. P. W. Buehler, B. Abraham, F. Vallelian, C. Linnemayr, C. P. Pereira, J. F. Cipollo, Y. Jia, M. Mikolajczyk, F. S. Boretti, G. Schoedon, A. I. Alayash and D. J. Schaer: Haptoglobin preserves the CD163 hemoglobin scavenger pathway by shielding hemoglobin from peroxidative modification. Blood, 113, 2578-86 (2009)
31. D. J. Schaer, A. I. Alayash and P. W. Buehler: Gating the radical hemoglobin to macrophages: the antiinflammatory role of CD163, a scavenger receptor. Antioxidants & Redox Signaling, 9, 991-9 (2007) (Pubitemid 46919600)
32. M. B. Graeber, B. W. Scheithauer and G. W. Kreutzberg: Microglia in brain tumors. Glia, 40, 252-9 (2002) (Pubitemid 35337382)
33. C. Soulas, R. E. Donahue, C. E. Dunbar, D. A. Persons, X. Alvarez and K. C. Williams: Genetically modified CD34+ hematopoietic stem cells contribute to turnover of brain perivascular macrophages in long-term repopulated primates. American Journal of Pathology, 174, 1808-17 (2009)
34. N. R. Miselis, Z. J. Wu, N. Van Rooijen and A. B. Kane: Targeting tumor-associated macrophages in an orthotopic murine model of diffuse malignant mesothelioma. Molecular Cancer Therapeutics, 7, 788-99 (2008) (Pubitemid 351551032)
35. I. G. Woods and A. F. Schier: Targeted mutagenesis in zebrafish. Nature Biotechnology, 26, 650-1 (2008) (Pubitemid 351809586)
36. H. Takai, M. Ashihara, T. Ishiguro, H. Terashima, T. Watanabe, A. Kato and M. Suzuki: Involvement of glypican-3 in the recruitment of M2-polarized tumor-associated macrophages in hepatocellular carcinoma. Cancer Biology & Therapy, 8:24, 1-10 (2009)
37. A. Mantovani, F. Marchesi, C. Porta, A. Sica and P. Allavena: Inflammation and cancer: breast cancer as a prototype. Breast, 16 Suppl 2, S27-33 (2007)
38. H. Kurahara, H. Shinchi, Y. Mataki, K. Maemura, H. Noma, F. Kubo, M. Sakoda, S. Ueno, S. Natsugoe and S. Takao: Significance of M2-polarized tumor-associated macrophage in pancreatic cancer. Journal of Surgical Research (2009)
39. A. Sica, P. Larghi, A. Mancino, L. Rubino, C. Porta, M. G. Totaro, M. Rimoldi, S. K. Biswas, P. Allavena and A. Mantovani: Macrophage polarization in tumour progression. Seminars in Cancer Biology, 18, 349-55 (2008)
40. M. A. Bouhlel, J. Brozek, B. Derudas, C. Zawadzki, B. Jude, B. Staels and G. Chinetti-Gbaguidi: Unlike PPARgamma, PPARalpha or PPARbeta/delta activation does not promote human monocyte differentiation toward alternative macrophages. Biochemical and Biophysical Research Communications, 386, 459-62 (2009)
41. A. Mantovani, A. Sica, P. Allavena, C. Garlanda and M. Locati: Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation. Human Immunology, 70, 325-30 (2009)
42. M. Leidi, E. Gotti, L. Bologna, E. Miranda, M. Rimoldi, A. Sica, M. Roncalli, G. A. Palumbo, M. Introna and J. Golay: M2 macrophages phagocytose rituximabopsonized leukemic targets more efficiently than m1 cells in vitro. Journal of Immunology, 182, 4415-22 (2009)
43. F. O. Martinez, S. Gordon, M. Locati and A. Mantovani: Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. Journal of Immunology, 177, 7303-11 (2006) (Pubitemid 44715100)
44. A. Michelucci, T. Heurtaux, L. Grandbarbe, E. Morga and P. Heuschling: Characterization of the microglial phenotype under specific pro-inflammatory and antiinflammatory conditions: Effects of oligomeric and fibrillar amyloid-beta. Journal of Neuroimmunology, 210, 3-12 (2009)
45. J. D. Ji, K. H. Park-Min and L. B. Ivashkiv: Expression and function of semaphorin 3A and its receptors in human monocyte-derived macrophages. Human Immunology, 70, 211-7 (2009)
46. S. Grinberg, G. Hasko, D. C. Wu and S. J. Leibovich: Suppression of PLCbeta2 by endotoxin plays a role in the adenosine A2A receptor-mediated switch of macrophages from an inflammatory to an angiogenic phenotype. American Journal of Pathology, 175, 2439-53 (2009)
47. M. A. Bouhlel, B. Derudas, E. Rigamonti, R. Dièvart, J. Brozek, S. Haulon, C. Zawadzki, B. Jude, G. Torpier, N. Marx, B. Staels and G. Chinetti-Gbaguidi: PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties. Cell Metabolism, 6, 137-43 (2007) (Pubitemid 47189091)
48. J. A. Van Ginderachter, K. Movahedi, J. Van Den Bossche and P. De Baetselier: Macrophages, PPARs, and Cancer. PPAR Research, 2008, 169414 (2008)
49. G. C. Daginakatte, S. M. Gianino, N. W. Zhao, A. S. Parsadanian and D. H. Gutmann: Increased c-Jun-NH2-kinase signaling in neurofibromatosis-1 heterozygous microglia drives microglia activation and promotes optic glioma proliferation. Cancer Research, 68, 10358-66 (2008)
50. G. C. Daginakatte and D. H. Gutmann: Neurofibromatosis-1 (Nf1) heterozygous brain microglia elaborate paracrine factors that promote Nf1-deficient astrocyte and glioma growth. Human Molecular Genetics, 16, 1098-112 (2007) (Pubitemid 47062730)
51. A. Flügel, M. S. Labeur, E. M. Grasbon-Frodl, G. W. Kreutzberg and M. B. Graeber: Microglia only weakly present glioma antigen to cytotoxic T cells. International Journal of Developmental Neuroscience, 17, 547-56 (1999) (Pubitemid 29421841)
52. M. Graeber and A. Flügel: Microglia and gliomas may have a symbiotic relationship. Journal of Neuroimmunology, 154, 178-178 (2003)
53. A. M. Kostianovsky, L. M. Maier, R. C. Anderson, J. N. Bruce and D. E. Anderson: Astrocytic regulation of human monocytic/microglial activation. Journal of Immunology, 181, 5425-32 (2008)
54. M. Rodero, Y. Marie, M. Coudert, E. Blondet, K. Mokhtari, A. Rousseau, W. Raoul, C. Carpentier, F. Sennlaub, P. Deterre, J. Y. Delattre, P. Debré, M. Sanson and C. Combadière: Polymorphism in the microglial cellmobilizing CX3CR1 gene is associated with survival in patients with glioblastoma. Journal of Clinical Oncology, 26, 5957-64 (2008)
55. A. Kulla, A. Liigant, A. Piirsoo, G. Rippin and T. Asser: Tenascin expression patterns and cells of monocyte lineage: relationship in human gliomas. Modern Pathology, 13, 56-67 (2000) (Pubitemid 30077905)
56. E. Alpsoy, V. Kodelja, S. Goerdt, C. E. Orfanos and C. Zouboulis: Serum of patients with Behçet's disease induces classical (pro-inflammatory) activation of human macrophages in vitro. Dermatology, 206, 225-32 (2003) (Pubitemid 36407830)
57. T. Avcin, S. M. Tse, R. Schneider, B. Ngan and E. D. Silverman: Macrophage activation syndrome as the presenting manifestation of rheumatic diseases in childhood. Journal of Pediatrics, 148, 683-6 (2006) (Pubitemid 43776910)
58. C. Buechler, M. Ritter, E. Orsó, T. Langmann, J. Klucken and G. Schmitz: Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro-and antiinflammatory stimuli. Journal of Leukocyte Biology, 67, 97-103 (2000) (Pubitemid 30046823)
59. R. Foresti, S. Bains, F. Sulc, P. J. Farmer, C. J. Green and R. Motterlini: The interaction of nitric oxide with distinct hemoglobins differentially amplifies endothelial heme uptake and heme oxygenase-1 expression. Journal of Pharmacology and Experimental Therapeutics, 317, 1125-33 (2006)
60. S. Gordon: Homeostasis: a scavenger receptor for haemoglobin. Current Biology, 11, R399-401 (2001) (Pubitemid 32442785)
61. J. H. Graversen, M. Madsen and S. K. Moestrup: CD163: a signal receptor scavenging haptoglobinhemoglobin complexes from plasma. International Journal of Biochemistry & Cell Biology, 34, 309-14 (2002) (Pubitemid 34164272)
62. P. Hogger and C. Sorg: Soluble CD163 inhibits phorbol ester-induced lymphocyte proliferation. Biochemical and Biophysical Research Communications, 288, 841-3 (2001) (Pubitemid 33140958)
63. C. W. Lam, S. J. Getting and M. Perretti: In vitro and in vivo induction of heme oxygenase 1 in mouse macrophages following melanocortin receptor activation. Journal of Immunology, 174, 2297-304 (2005) (Pubitemid 40223978)
64. M. B. Maniecki, H. J. Møller, S. K. Moestrup and B. K. Møller: CD163 positive subsets of blood dendritic cells: the scavenging macrophage receptors CD163 and CD91 are coexpressed on human dendritic cells and monocytes. Immunobiology, 211, 407-17 (2006)
65. M. J. Paul-Clark, F. Roviezzo, R. J. Flower, G. Cirino, P. D. Soldato, I. M. Adcock and M. Perretti: Glucocorticoid receptor nitration leads to enhanced anti-inflammatory effects of novel steroid ligands. Journal of Immunology, 171, 3245-52 (2003) (Pubitemid 37093551)
66. P. A. Pioli, K. E. Goonan, K. Wardwell and P. M. Guyre: TGF-beta regulation of human macrophage scavenger receptor CD163 is Smad3-dependent. Journal of Leukocyte Biology, 76, 500-8 (2004) (Pubitemid 39006966)
67. C. A. Schaer, G. Schoedon, A. Imhof, M. O. Kurrer and D. J. Schaer: Constitutive endocytosis of CD163 mediates hemoglobin-heme uptake and determines the noninflammatory and protective transcriptional response of macrophages to hemoglobin. Circulation Research, 99, 943-50 (2006) (Pubitemid 44657797)
68. D. J. Schaer, F. S. Boretti, G. Schoedon and A. Schaffner: Induction of the CD163-dependent haemoglobin uptake by macrophages as a novel anti-inflammatory action of glucocorticoids. British Journal of Haematology, 119, 239-43 (2002) (Pubitemid 35176525)
69. J. Simoni, G. Simoni, J. A. Griswold, J. F. Moeller, J. P. Tsikouris, A. Khanna, C. Roongsritong and D. E. Wesson: Role of free hemoglobin in 8-iso prostaglandin F2-alpha synthesis in chronic renal failure and its impact on CD163-Hb scavenger receptor and on coronary artery endothelium. ASAIO Journal, 52, 652-61 (2006) (Pubitemid 44784567)
70. T. H. Sulahian, P. Hogger, A. E. Wahner, K. Wardwell, N. J. Goulding, C. Sorg, A. Droste, M. Stehling, P. K. Wallace, P. M. Morganelli and P. M. Guyre: Human monocytes express CD163, which is upregulated by IL-10 and identical to p155. Cytokine, 12, 1312-21 (2000)
71. J. S. Welch, L. Escoubet-Lozach, D. B. Sykes, K. Liddiard, D. R. Greaves and C. K. Glass: TH2 cytokines and allergic challenge induce Ym1 expression in macrophages by a STAT6-dependent mechanism. Journal of Biological Chemistry, 277, 42821-9 (2002) (Pubitemid 35285658)