메뉴 건너뛰기




Volumn 25, Issue 6, 2011, Pages 833-837

Chrysophanic acid blocks proliferation of colon cancer cells by inhibiting EGFR/mTOR pathway

Author keywords

chrysophanic acid; colon cancer; EGFR; mTOR

Indexed keywords

CHOLECYSTOKININ OCTAPEPTIDE; CHRYSOPHANIC ACID; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RAPAMYCIN; S6 KINASE;

EID: 79957873765     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3323     Document Type: Article
Times cited : (52)

References (30)
  • 1
    • 34250619165 scopus 로고    scopus 로고
    • The mammalian target of rapamycin signaling pathway: Twists and turns in the road to cancer therapy
    • DOI 10.1158/1078-0432.CCR-06-2798
    • Abraham RT, Gibbons JJ,. 2007. The mammalian target of rapamycin signaling pathway: twists and turns in the road to cancer therapy. Clin Cancer Res 13: 3109-3114. (Pubitemid 46944891)
    • (2007) Clinical Cancer Research , vol.13 , Issue.11 , pp. 3109-3114
    • Abraham, R.T.1    Gibbons, J.J.2
  • 2
    • 77955782186 scopus 로고    scopus 로고
    • Antiproliferative effect of rhein, an anthraquinone isolated from Cassia species, on Caco-2 human adenocarcinoma cells
    • Aviello G, Rowland I, Gill CI, et al. 2009. Antiproliferative effect of rhein, an anthraquinone isolated from Cassia species, on Caco-2 human adenocarcinoma cells. J Cell Mol Med 14: 2006-2014.
    • (2009) J Cell Mol Med , vol.14 , pp. 2006-2014
    • Aviello, G.1    Rowland, I.2    Gill, C.I.3
  • 4
    • 2342559981 scopus 로고    scopus 로고
    • The TOR pathway: A target for cancer therapy
    • Bjornsti MA, Houghton PJ,. 2004. The TOR pathway: a target for cancer therapy. Nat Rev Cancer 4: 335-348. (Pubitemid 38579480)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.5 , pp. 335-348
    • Bjornsti, M.-A.1    Houghton, P.J.2
  • 6
    • 0033543544 scopus 로고    scopus 로고
    • The role of individual SH2 domains in mediating association of phospholipase C-gamma1 with the activated EGF receptor
    • Chattopadhyay A, Vecchi M, Ji Q, et al. 1999. The role of individual SH2 domains in mediating association of phospholipase C-gamma1 with the activated EGF receptor. J Biol Chem 274: 26091-26097.
    • (1999) J Biol Chem , vol.274 , pp. 26091-26097
    • Chattopadhyay, A.1    Vecchi, M.2    Ji, Q.3
  • 7
    • 34548551206 scopus 로고    scopus 로고
    • Anthraquinones, Cdc25B phosphatase inhibitors, isolated from the roots of Polygonum multiflorum Thunb
    • DOI 10.1080/14786410601012265, PII 778578249
    • Choi SG, Kim J, Sung ND, et al. 2007. Anthraquinones, Cdc25B phosphatase inhibitors, isolated from the roots of Polygonum multiflorum Thunb. Nat Prod Res 21: 487-493. (Pubitemid 47393737)
    • (2007) Natural Product Research , vol.21 , Issue.6 , pp. 487-493
    • Choi, S.-G.1    Kim, J.2    Sung, N.-D.3    Son, K.-H.4    Cheon, H.-G.5    Kim, K.-R.6    Kwon, B.-M.7
  • 8
    • 70349696530 scopus 로고    scopus 로고
    • EGFR-dependent and independent activation of Akt/mTOR cascade in bone and soft tissue tumors
    • Dobashi Y, Suzuki S, Sato E, et al. 2009. EGFR-dependent and independent activation of Akt/mTOR cascade in bone and soft tissue tumors. Mod Pathol 22: 1328-1340.
    • (2009) Mod Pathol , vol.22 , pp. 1328-1340
    • Dobashi, Y.1    Suzuki, S.2    Sato, E.3
  • 10
    • 51649126752 scopus 로고    scopus 로고
    • Inhibition of the mTORC1 pathway suppresses intestinal polyp formation and reduces mortality in ApcDelta716 mice
    • Fujishita T, Aoki K, Lane HA, et al. 2008. Inhibition of the mTORC1 pathway suppresses intestinal polyp formation and reduces mortality in ApcDelta716 mice. Proc Natl Acad Sci USA 105: 13544-13549.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 13544-13549
    • Fujishita, T.1    Aoki, K.2    Lane, H.A.3
  • 11
    • 1842471336 scopus 로고    scopus 로고
    • Signaling through the epidermal growth factor receptor during the development of malignancy
    • DOI 10.1016/j.pharmthera.2004.01.002, PII S0163725804000208
    • Grandis JR, Sok JC,. 2004. Signaling through the epidermal growth factor receptor during the development of malignancy. Pharmacol Ther 102: 37-46. (Pubitemid 38429984)
    • (2004) Pharmacology and Therapeutics , vol.102 , Issue.1 , pp. 37-46
    • Grandis, J.R.1    Sok, J.C.2
  • 13
    • 0343526523 scopus 로고    scopus 로고
    • Anthraquinone cytotoxicity and apoptosis in primary cultures of rat hepatocytes
    • DOI 10.1080/10715769900300981
    • KÃ¥gedal K, Bironaite D, Ollinger K,. 1999. Anthraquinone cytotoxicity and apoptosis in primary cultures of rat hepatocytes. Free Radic Res 31: 419-428. (Pubitemid 29531122)
    • (1999) Free Radical Research , vol.31 , Issue.5 , pp. 419-428
    • Kagedal, K.1    Bironalte, D.2    Ollinger, K.3
  • 14
    • 45749113031 scopus 로고    scopus 로고
    • Anti-proliferative effects of estrogen receptor-modulating compounds isolated from Rheum palmatum
    • Kang SC, Lee CM, Choung ES, et al. 2008. Anti-proliferative effects of estrogen receptor-modulating compounds isolated from Rheum palmatum. Arch Pharm Res 31: 722-726.
    • (2008) Arch Pharm Res , vol.31 , pp. 722-726
    • Kang, S.C.1    Lee, C.M.2    Choung, E.S.3
  • 15
    • 77950076456 scopus 로고    scopus 로고
    • Aloe-emodin induces apoptosis of human nasopharyngeal carcinoma cells via caspase-8-mediated activation of the mitochondrial death pathway
    • Lin ML, Lu YC, Chung JG, et al. 2010. Aloe-emodin induces apoptosis of human nasopharyngeal carcinoma cells via caspase-8-mediated activation of the mitochondrial death pathway. Cancer Lett 291: 46-58.
    • (2010) Cancer Lett , vol.291 , pp. 46-58
    • Lin, M.L.1    Lu, Y.C.2    Chung, J.G.3
  • 16
    • 77954648680 scopus 로고    scopus 로고
    • Chrysophanol induces necrosis through the production of ROS and alteration of ATP levels in J5 human liver cancer cells
    • in print
    • Lu CC, Yang JS, Huang AC, et al. 2010. Chrysophanol induces necrosis through the production of ROS and alteration of ATP levels in J5 human liver cancer cells. Mol Nutr Food Res: in print.
    • (2010) Mol Nutr Food Res
    • Lu, C.C.1    Yang, J.S.2    Huang, A.C.3
  • 17
    • 0036342294 scopus 로고    scopus 로고
    • Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/Akt pathway
    • DOI 10.1016/S1097-2765(02)00568-3
    • Manning BD, Tee AR, Logsdon MN, et al. 2002. Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway. Mol Cell 10: 151-162. (Pubitemid 34876569)
    • (2002) Molecular Cell , vol.10 , Issue.1 , pp. 151-162
    • Manning, B.D.1    Tee, A.R.2    Logsdon M.Nicole3    Blenis, J.4    Cantley, L.C.5
  • 18
    • 73349119689 scopus 로고    scopus 로고
    • High risk of recurrence for patients with breast cancer who have human epidermal growth factor receptor 2-positive, node-negative tumors 1 cm or smaller
    • Meric-Bernstam F, Gonzalez-Angulo AM,. 2009. High risk of recurrence for patients with breast cancer who have human epidermal growth factor receptor 2-positive, node-negative tumors 1 cm or smaller. J Clin Oncol 27: 2278-2287.
    • (2009) J Clin Oncol , vol.27 , pp. 2278-2287
    • Meric-Bernstam, F.1    Gonzalez-Angulo, A.M.2
  • 20
    • 0036185848 scopus 로고    scopus 로고
    • The protein kinase B/Akt signalling pathway in human malignancy
    • DOI 10.1016/S0898-6568(01)00271-6, PII S0898656801002716
    • Nicholson KM, Anderson NG,. 2002. The protein kinase B/Akt signalling pathway in human malignancy. Cell Signal 14: 381-395. (Pubitemid 34214843)
    • (2002) Cellular Signalling , vol.14 , Issue.5 , pp. 381-395
    • Nicholson, K.M.1    Anderson, N.G.2
  • 22
    • 33845261007 scopus 로고    scopus 로고
    • Molecular determination of epidermal growth factor receptor in normal and neoplastic colorectal mucosa
    • DOI 10.1038/sj.bjc.6603441, PII 6603441
    • Piazzi G, Paterini P, Ceccarelli C, et al. 2006. Molecular determination of epidermal growth factor receptor in normal and neoplastic colorectal mucosa. Br J Cancer 95: 1525-1528. (Pubitemid 44863355)
    • (2006) British Journal of Cancer , vol.95 , Issue.11 , pp. 1525-1528
    • Piazzi, G.1    Paterini, P.2    Ceccarelli, C.3    Pantaleo, M.A.4    Biasco, G.5
  • 23
    • 0028960781 scopus 로고
    • Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells
    • Radinsky R, Risin S, Fan D, et al. 1995. Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells. Clin Cancer Res 1: 19-31.
    • (1995) Clin Cancer Res , vol.1 , pp. 19-31
    • Radinsky, R.1    Risin, S.2    Fan, D.3
  • 24
    • 4344683428 scopus 로고    scopus 로고
    • Differential activation of Epidermal Growth Factor (EGF) receptor downstream signaling pathways by betacellulin and EGF
    • DOI 10.1210/en.2004-0401
    • Saito T, Okada S, Ohshima K, et al. 2004. Differential activation of epidermal growth factor (EGF) receptor downstream signaling pathways by betacellulin and EGF. Endocrinology 145: 4232-4243. (Pubitemid 39120572)
    • (2004) Endocrinology , vol.145 , Issue.9 , pp. 4232-4243
    • Saito, T.1    Okada, S.2    Ohshima, K.3    Yamada, E.4    Sato, M.5    Uehara, Y.6    Shimizu, H.7    Pessin, J.E.8    Mori, M.9
  • 25
    • 0028955388 scopus 로고
    • Epidermal growth factor-related peptides and their receptors in human malignancies
    • Salomon DS, Brandt R, Ciardiello F, et al. 1995. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 19: 183-232.
    • (1995) Crit Rev Oncol Hematol , vol.19 , pp. 183-232
    • Salomon, D.S.1    Brandt, R.2    Ciardiello, F.3
  • 26
    • 57449096129 scopus 로고    scopus 로고
    • Five-year data and prognostic factor analysis of oxaliplatin and irinotecan combinations for advanced colorectal cancer: N9741
    • Sanoff HK, Sargent DJ, Campbell ME, et al. 2008. Five-year data and prognostic factor analysis of oxaliplatin and irinotecan combinations for advanced colorectal cancer: N9741. J Clin Oncol 26: 5721-5727.
    • (2008) J Clin Oncol , vol.26 , pp. 5721-5727
    • Sanoff, H.K.1    Sargent, D.J.2    Campbell, M.E.3
  • 27
    • 20444505248 scopus 로고    scopus 로고
    • Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway
    • Su YT, Chang HL, Shyue SK, et al. 2005. Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway. Biochem Pharmacol 70: 229-241.
    • (2005) Biochem Pharmacol , vol.70 , pp. 229-241
    • Su, Y.T.1    Chang, H.L.2    Shyue, S.K.3
  • 28
    • 0029052358 scopus 로고
    • Induction of apoptosis by T-2 toxin and other natural toxins in HL-60 human promyelotic leukemia cells
    • Ueno Y, Umemori K, Niimi E, et al. 1995. Induction of apoptosis by T-2 toxin and other natural toxins in HL-60 human promyelotic leukemia cells. Nat Toxins 3: 129-137.
    • (1995) Nat Toxins , vol.3 , pp. 129-137
    • Ueno, Y.1    Umemori, K.2    Niimi, E.3
  • 30
    • 68949198785 scopus 로고    scopus 로고
    • MTOR signaling pathway is a target for the treatment of colorectal cancer
    • Zhang YJ, Dai Q, Sun DF, et al. 2009. mTOR signaling pathway is a target for the treatment of colorectal cancer. Ann Surg Oncol 16: 2617-2628.
    • (2009) Ann Surg Oncol , vol.16 , pp. 2617-2628
    • Zhang, Y.J.1    Dai, Q.2    Sun, D.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.