-
1
-
-
34250619165
-
The mammalian target of rapamycin signaling pathway: Twists and turns in the road to cancer therapy
-
DOI 10.1158/1078-0432.CCR-06-2798
-
Abraham RT, Gibbons JJ,. 2007. The mammalian target of rapamycin signaling pathway: twists and turns in the road to cancer therapy. Clin Cancer Res 13: 3109-3114. (Pubitemid 46944891)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.11
, pp. 3109-3114
-
-
Abraham, R.T.1
Gibbons, J.J.2
-
2
-
-
77955782186
-
Antiproliferative effect of rhein, an anthraquinone isolated from Cassia species, on Caco-2 human adenocarcinoma cells
-
Aviello G, Rowland I, Gill CI, et al. 2009. Antiproliferative effect of rhein, an anthraquinone isolated from Cassia species, on Caco-2 human adenocarcinoma cells. J Cell Mol Med 14: 2006-2014.
-
(2009)
J Cell Mol Med
, vol.14
, pp. 2006-2014
-
-
Aviello, G.1
Rowland, I.2
Gill, C.I.3
-
3
-
-
40349108627
-
Inhibition of mTOR pathway by everolimus cooperates with EGFR inhibitors in human tumours sensitive and resistant to anti-EGFR drugs
-
DOI 10.1038/sj.bjc.6604269, PII 6604269
-
Bianco R, Garofalo S, Rosa R, et al. 2008. Inhibition of mTOR pathway by everolimus cooperates with EGFR inhibitors in human tumours sensitive and resistant to anti-EGFR drugs. Br J Cancer 98: 923-930. (Pubitemid 351341618)
-
(2008)
British Journal of Cancer
, vol.98
, Issue.5
, pp. 923-930
-
-
Bianco, R.1
Garofalo, S.2
Rosa, R.3
Damiano, V.4
Gelardi, T.5
Daniele, G.6
Marciano, R.7
Ciardiello, F.8
Tortora, G.9
-
4
-
-
2342559981
-
The TOR pathway: A target for cancer therapy
-
Bjornsti MA, Houghton PJ,. 2004. The TOR pathway: a target for cancer therapy. Nat Rev Cancer 4: 335-348. (Pubitemid 38579480)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.5
, pp. 335-348
-
-
Bjornsti, M.-A.1
Houghton, P.J.2
-
5
-
-
33845227643
-
Rapamycin synergizes with the epidermal growth factor receptor inhibitor erlotinib in non-small-cell lung, pancreatic, colon, and breast tumors
-
DOI 10.1158/1535-7163.MCT-06-0166
-
Buck E, Eyzaguirre A, Brown E, et al. 2006. Rapamycin synergizes with the epidermal growth factor receptor inhibitor erlotinib in non-small-cell lung, pancreatic, colon, and breast tumors. Mol Cancer Ther 5: 2676-2684. (Pubitemid 44848994)
-
(2006)
Molecular Cancer Therapeutics
, vol.5
, Issue.11
, pp. 2676-2684
-
-
Buck, E.1
Eyzaguirre, A.2
Brown, E.3
Petti, F.4
McCormack, S.5
Haley, J.D.6
Iwata, K.K.7
Gibson, N.W.8
Griffin, G.9
-
6
-
-
0033543544
-
The role of individual SH2 domains in mediating association of phospholipase C-gamma1 with the activated EGF receptor
-
Chattopadhyay A, Vecchi M, Ji Q, et al. 1999. The role of individual SH2 domains in mediating association of phospholipase C-gamma1 with the activated EGF receptor. J Biol Chem 274: 26091-26097.
-
(1999)
J Biol Chem
, vol.274
, pp. 26091-26097
-
-
Chattopadhyay, A.1
Vecchi, M.2
Ji, Q.3
-
7
-
-
34548551206
-
Anthraquinones, Cdc25B phosphatase inhibitors, isolated from the roots of Polygonum multiflorum Thunb
-
DOI 10.1080/14786410601012265, PII 778578249
-
Choi SG, Kim J, Sung ND, et al. 2007. Anthraquinones, Cdc25B phosphatase inhibitors, isolated from the roots of Polygonum multiflorum Thunb. Nat Prod Res 21: 487-493. (Pubitemid 47393737)
-
(2007)
Natural Product Research
, vol.21
, Issue.6
, pp. 487-493
-
-
Choi, S.-G.1
Kim, J.2
Sung, N.-D.3
Son, K.-H.4
Cheon, H.-G.5
Kim, K.-R.6
Kwon, B.-M.7
-
8
-
-
70349696530
-
EGFR-dependent and independent activation of Akt/mTOR cascade in bone and soft tissue tumors
-
Dobashi Y, Suzuki S, Sato E, et al. 2009. EGFR-dependent and independent activation of Akt/mTOR cascade in bone and soft tissue tumors. Mod Pathol 22: 1328-1340.
-
(2009)
Mod Pathol
, vol.22
, pp. 1328-1340
-
-
Dobashi, Y.1
Suzuki, S.2
Sato, E.3
-
9
-
-
42449131403
-
Epidermal growth factor receptor controls flat dysplastic aberrant crypt foci development and colon cancer progression in the rat azoxymethane model
-
DOI 10.1158/1078-0432.CCR-07-4926
-
Dougherty U, Sehdev A, Cerda S, et al. 2008. Epidermal growth factor receptor controls flat dysplastic aberrant crypt foci development and colon cancer progression in the rat azoxymethane model. Clin Cancer Res 14: 2253-2262. (Pubitemid 351559573)
-
(2008)
Clinical Cancer Research
, vol.14
, Issue.8
, pp. 2253-2262
-
-
Dougherty, U.1
Sehdev, A.2
Cerda, S.3
Mustafi, R.4
Little, N.5
Yuan, W.6
Jagadeeswaran, S.7
Chumsangsri, A.8
Delgado, J.9
Tretiakova, M.10
Joseph, L.11
Hart, J.12
Cohen, E.E.W.13
Aluri, L.14
Fichera, A.15
Bissonnette, M.16
-
10
-
-
51649126752
-
Inhibition of the mTORC1 pathway suppresses intestinal polyp formation and reduces mortality in ApcDelta716 mice
-
Fujishita T, Aoki K, Lane HA, et al. 2008. Inhibition of the mTORC1 pathway suppresses intestinal polyp formation and reduces mortality in ApcDelta716 mice. Proc Natl Acad Sci USA 105: 13544-13549.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13544-13549
-
-
Fujishita, T.1
Aoki, K.2
Lane, H.A.3
-
11
-
-
1842471336
-
Signaling through the epidermal growth factor receptor during the development of malignancy
-
DOI 10.1016/j.pharmthera.2004.01.002, PII S0163725804000208
-
Grandis JR, Sok JC,. 2004. Signaling through the epidermal growth factor receptor during the development of malignancy. Pharmacol Ther 102: 37-46. (Pubitemid 38429984)
-
(2004)
Pharmacology and Therapeutics
, vol.102
, Issue.1
, pp. 37-46
-
-
Grandis, J.R.1
Sok, J.C.2
-
12
-
-
34548047015
-
Anti-cancer properties of anthraquinones from rhubarb
-
DOI 10.1002/med.20094
-
Huang Q, Lu G, Shen HM, et al. 2007. Anti-cancer properties of anthraquinones from rhubarb. Med Res Rev 27: 609-630. (Pubitemid 47282446)
-
(2007)
Medicinal Research Reviews
, vol.27
, Issue.5
, pp. 609-630
-
-
Huang, Q.1
Lu, G.2
Shen, H.-M.3
Chung, M.C.M.4
Choon, N.O.5
-
13
-
-
0343526523
-
Anthraquinone cytotoxicity and apoptosis in primary cultures of rat hepatocytes
-
DOI 10.1080/10715769900300981
-
KÃ¥gedal K, Bironaite D, Ollinger K,. 1999. Anthraquinone cytotoxicity and apoptosis in primary cultures of rat hepatocytes. Free Radic Res 31: 419-428. (Pubitemid 29531122)
-
(1999)
Free Radical Research
, vol.31
, Issue.5
, pp. 419-428
-
-
Kagedal, K.1
Bironalte, D.2
Ollinger, K.3
-
14
-
-
45749113031
-
Anti-proliferative effects of estrogen receptor-modulating compounds isolated from Rheum palmatum
-
Kang SC, Lee CM, Choung ES, et al. 2008. Anti-proliferative effects of estrogen receptor-modulating compounds isolated from Rheum palmatum. Arch Pharm Res 31: 722-726.
-
(2008)
Arch Pharm Res
, vol.31
, pp. 722-726
-
-
Kang, S.C.1
Lee, C.M.2
Choung, E.S.3
-
15
-
-
77950076456
-
Aloe-emodin induces apoptosis of human nasopharyngeal carcinoma cells via caspase-8-mediated activation of the mitochondrial death pathway
-
Lin ML, Lu YC, Chung JG, et al. 2010. Aloe-emodin induces apoptosis of human nasopharyngeal carcinoma cells via caspase-8-mediated activation of the mitochondrial death pathway. Cancer Lett 291: 46-58.
-
(2010)
Cancer Lett
, vol.291
, pp. 46-58
-
-
Lin, M.L.1
Lu, Y.C.2
Chung, J.G.3
-
16
-
-
77954648680
-
Chrysophanol induces necrosis through the production of ROS and alteration of ATP levels in J5 human liver cancer cells
-
in print
-
Lu CC, Yang JS, Huang AC, et al. 2010. Chrysophanol induces necrosis through the production of ROS and alteration of ATP levels in J5 human liver cancer cells. Mol Nutr Food Res: in print.
-
(2010)
Mol Nutr Food Res
-
-
Lu, C.C.1
Yang, J.S.2
Huang, A.C.3
-
17
-
-
0036342294
-
Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/Akt pathway
-
DOI 10.1016/S1097-2765(02)00568-3
-
Manning BD, Tee AR, Logsdon MN, et al. 2002. Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway. Mol Cell 10: 151-162. (Pubitemid 34876569)
-
(2002)
Molecular Cell
, vol.10
, Issue.1
, pp. 151-162
-
-
Manning, B.D.1
Tee, A.R.2
Logsdon M.Nicole3
Blenis, J.4
Cantley, L.C.5
-
18
-
-
73349119689
-
High risk of recurrence for patients with breast cancer who have human epidermal growth factor receptor 2-positive, node-negative tumors 1 cm or smaller
-
Meric-Bernstam F, Gonzalez-Angulo AM,. 2009. High risk of recurrence for patients with breast cancer who have human epidermal growth factor receptor 2-positive, node-negative tumors 1 cm or smaller. J Clin Oncol 27: 2278-2287.
-
(2009)
J Clin Oncol
, vol.27
, pp. 2278-2287
-
-
Meric-Bernstam, F.1
Gonzalez-Angulo, A.M.2
-
20
-
-
0036185848
-
The protein kinase B/Akt signalling pathway in human malignancy
-
DOI 10.1016/S0898-6568(01)00271-6, PII S0898656801002716
-
Nicholson KM, Anderson NG,. 2002. The protein kinase B/Akt signalling pathway in human malignancy. Cell Signal 14: 381-395. (Pubitemid 34214843)
-
(2002)
Cellular Signalling
, vol.14
, Issue.5
, pp. 381-395
-
-
Nicholson, K.M.1
Anderson, N.G.2
-
22
-
-
33845261007
-
Molecular determination of epidermal growth factor receptor in normal and neoplastic colorectal mucosa
-
DOI 10.1038/sj.bjc.6603441, PII 6603441
-
Piazzi G, Paterini P, Ceccarelli C, et al. 2006. Molecular determination of epidermal growth factor receptor in normal and neoplastic colorectal mucosa. Br J Cancer 95: 1525-1528. (Pubitemid 44863355)
-
(2006)
British Journal of Cancer
, vol.95
, Issue.11
, pp. 1525-1528
-
-
Piazzi, G.1
Paterini, P.2
Ceccarelli, C.3
Pantaleo, M.A.4
Biasco, G.5
-
23
-
-
0028960781
-
Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells
-
Radinsky R, Risin S, Fan D, et al. 1995. Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells. Clin Cancer Res 1: 19-31.
-
(1995)
Clin Cancer Res
, vol.1
, pp. 19-31
-
-
Radinsky, R.1
Risin, S.2
Fan, D.3
-
24
-
-
4344683428
-
Differential activation of Epidermal Growth Factor (EGF) receptor downstream signaling pathways by betacellulin and EGF
-
DOI 10.1210/en.2004-0401
-
Saito T, Okada S, Ohshima K, et al. 2004. Differential activation of epidermal growth factor (EGF) receptor downstream signaling pathways by betacellulin and EGF. Endocrinology 145: 4232-4243. (Pubitemid 39120572)
-
(2004)
Endocrinology
, vol.145
, Issue.9
, pp. 4232-4243
-
-
Saito, T.1
Okada, S.2
Ohshima, K.3
Yamada, E.4
Sato, M.5
Uehara, Y.6
Shimizu, H.7
Pessin, J.E.8
Mori, M.9
-
25
-
-
0028955388
-
Epidermal growth factor-related peptides and their receptors in human malignancies
-
Salomon DS, Brandt R, Ciardiello F, et al. 1995. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 19: 183-232.
-
(1995)
Crit Rev Oncol Hematol
, vol.19
, pp. 183-232
-
-
Salomon, D.S.1
Brandt, R.2
Ciardiello, F.3
-
26
-
-
57449096129
-
Five-year data and prognostic factor analysis of oxaliplatin and irinotecan combinations for advanced colorectal cancer: N9741
-
Sanoff HK, Sargent DJ, Campbell ME, et al. 2008. Five-year data and prognostic factor analysis of oxaliplatin and irinotecan combinations for advanced colorectal cancer: N9741. J Clin Oncol 26: 5721-5727.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5721-5727
-
-
Sanoff, H.K.1
Sargent, D.J.2
Campbell, M.E.3
-
27
-
-
20444505248
-
Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway
-
Su YT, Chang HL, Shyue SK, et al. 2005. Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway. Biochem Pharmacol 70: 229-241.
-
(2005)
Biochem Pharmacol
, vol.70
, pp. 229-241
-
-
Su, Y.T.1
Chang, H.L.2
Shyue, S.K.3
-
28
-
-
0029052358
-
Induction of apoptosis by T-2 toxin and other natural toxins in HL-60 human promyelotic leukemia cells
-
Ueno Y, Umemori K, Niimi E, et al. 1995. Induction of apoptosis by T-2 toxin and other natural toxins in HL-60 human promyelotic leukemia cells. Nat Toxins 3: 129-137.
-
(1995)
Nat Toxins
, vol.3
, pp. 129-137
-
-
Ueno, Y.1
Umemori, K.2
Niimi, E.3
-
30
-
-
68949198785
-
MTOR signaling pathway is a target for the treatment of colorectal cancer
-
Zhang YJ, Dai Q, Sun DF, et al. 2009. mTOR signaling pathway is a target for the treatment of colorectal cancer. Ann Surg Oncol 16: 2617-2628.
-
(2009)
Ann Surg Oncol
, vol.16
, pp. 2617-2628
-
-
Zhang, Y.J.1
Dai, Q.2
Sun, D.F.3
|