TBI translational rehabilitation research in the 21st Century: Exploring a Rehabilomics research model

European Journal of Physical and Rehabilitation Medicine

Volumn 46, Issue 4, 2010, Pages 549-555

  Wagner, A K ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Brain injuries Rehabilitation Biological markers Evidence based medicine Rehabilomics

Indexed keywords

BIOLOGICAL MARKER;

ADAPTATION; ARTICLE; BRAIN INJURY; CONVALESCENCE; DISABILITY; HEALTH CARE QUALITY; HUMAN; MEDICAL RESEARCH; PROGNOSIS;

ADAPTATION, PHYSIOLOGICAL; BIOLOGICAL MARKERS; BIOMEDICAL RESEARCH; BRAIN INJURIES; DISABILITY EVALUATION; HUMANS; PROGNOSIS; RECOVERY OF FUNCTION; STANDARD OF CARE;

EID: 79957842259     PISSN: 19739087     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (31)

1. Langlois JA, Rutland-Brown W, Thomas KE. Traumatic Brain Injury in the United States: Emergency Department Visits, Hospitalizations, and Deaths. Atlanta, Georgia: Centers for Disease Control and Prevention; 2006.
2. Wyszynski ME. Shaken Baby Syndrome: Identiication, Intervention and Prevention. Clin Excel Nurse Pract 1999;3:2627.
3. Emerging health concerns. TBI. Deployment Health Clinical Center [Internet]. Available from http://www.pdhealth.mil/TBI. asp [cited 2009, Mar 18].
4. U.S Congressional Research Service. United States Military Casualty Statistics: Operation Iraqi Freedom and Operation Enduring Freedom (RS22452; Sep. 9, 2008) by Hannah Fischer.
5. Tagliaferri F, Compagnone C, Korsic M, Servadei F, Kraus J. A systematic review of brain injury epidemiology in Europe. Acta Neurochir 2006;148:255-68.
6. Hyder AA, Wunderlich CA, Puvanachandra P, Gururaj G, Kobusingye OC. The impact of traumatic brain injuries: a global perspective. NeuroRehabilitation 2007;22:341-53.
7. The NIH Common Fund [Internet]. Available from http://nihroadmap. nih.gov [cited 2010, Oct 18].
8. Foundation for the National Institutes of Health [Internet]. Available from http://www.fnih.org/ [cited 2010, Oct 18].
9. Bilder RM, Sabb FW, Cannon TD, London ED, Jentsch JD, Parker DS et al. The systematic study of phenotypes on a genomewide scale. Neuroscience 2009;164:30-42.
10. Schuntermann MF. The International Classiication of Impairments, Disabilities and Handicaps (ICIDH)-results and problems. Int J Rehabil Res 1996;19:1-11.
11. Bornman J. The World Health Organisation's terminology and classiication application to severe disability. Disabil Rehabil 2004;26:1828.
12. Dahl TH. International classiication of functioning, disability and health: an introduction and discussion of its potential impact on rehabilitation services and research. J Rehabil Med 2002;34:2014.
13. University of Pittsburgh [Homepage]. Available from www.rehabilomics. pitt.edu [cited 2010, Oct 18].
14. Teasdale GM, Murray GD, Nicoll JA. The association between APOE epsilon4, age and outcome after head injury: a prospective cohort study. Brain 2005;128:2556-61.
15. Johnson VE, Stewart W, Stewart JE, Graham DI, Praestgaard AH, Smith DH. A Neprilysin Polymorphism and Amyloid-beta Plaques Following Traumatic Brain Injury [Epub ahead of print]. J Neurotrauma 2009;26:1197-202.
16. Wagner AK, Ren D, Conley YP, Ma X, Kerr ME, Zafonte RD et al. Sex and genetic associations with cerebrospinal luid dopamine and metabolite production after severe traumatic brain injury. J Neurosurg 2007;106:538-47.
17. McAllister TW, Flashman LA, Harker RC, Tyler AL, Moore JH, Saykin AJ et al. Single nucleotide polymorphisms in ANKK1 and the dopamine D2 receptor gene affect cognitive outcome shortly after traumatic brain injury: a replication and extension study. Brain Inj 2008;22:705-14.
18. Wagner AK, Miller MA, Scanlon, J, Ren D, Kochanek PM, Conley YP. Adenosine A1 Receptor Gene Variant Associated with Posttraumatic Seizures after Severe TBI. Epilepsy Res 2010;90:259-72.
19. Dash PK, Kobori N, Moore AN. A molecular description of brain trauma pathophysiology using microarray technology: an overview. Neurochem Res 2004;29:1275-86.
20. Ishikawa Y, Uchino H, Morota S, Li C, Takahashi T, Ikeda Y et al. Search for novel gene markers of traumatic brain injury by time differential microarray analysis. Acta Neurochir Suppl 2006;96:1637.
21. Michael DB, Byers DM, Irwin LN. Gene expression following traumatic brain injury in humans: analysis by microarray. J Clin Neurosci 2005;12:284-90.
22. Crack PJ, Gould J, Bye N, Ross S, Ali U, Habgood MD, Morganti-Kossman C et al. The genomic proile of the cerebral cortex after closed head injury in mice: effects of minocycline. J Neural Transm 2009;116:1-12.
23. Berman BP, Weisenberger DJ, Laird PW. Locking in on the human methylome. Nat Biotechnol 2009;27:3412.
24. Berger RP. The use of serum biomarkers to predict outcome after traumatic brain injury in adults and children. J Head Trauma Rehabil 2006;21:315-33.
25. Kochanek PM, Berger RP, Bayir H, Wagner AK, Jenkins LW, Clark RS. Biomarkers of primary and evolving damage in traumatic and ischemic brain injury: diagnosis, prognosis, probing mechanisms, and therapeutic decision making. Curr Opin Crit Care 2008;14:135-41.
26. Wagner AK, Hammond F, Sasser H, Wiercisiewski D, Norton HJ. Use of Injury Severity Variables in Determining Disability and Community Integration after Traumatic Brain Injury. J Trauma 2000;49:4119.
27. Wagner AK, McCullough EH, Niyonkuru C. Acute serum hormone levels: characterization and prognosis after severe traumatic brain injury. [In press].
28. Hobbs A. Mapping variation in brain structure and function: implications for rehabilitation. J. Head Trauma Rehabil 1999;14:616-21.
29. Ricker JH, Hillary FG, DeLuca J. Functionally activated brain imaging (O-15 PET and fMRI) in the study of learning and memory after traumatic brain injury. J Head Trauma Rehabil 2001;16:191-205.
30. Rice F, Abraham R, Rudrasingham V, Owen MJ, Williams J. Memory for new information as a cognitive marker of liability to Alzheimer's disease in a high risk group: a research note. Int J Geriatr Psychiatry 2003;18:155-60.
31. Narayan RK, Michel ME, Ansell B, Baethmann A, Biegon A, Bracken MB et al. Clinical trials in head injury. J. Neurotrauma 2002;19:503-57.