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79957822925
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The assignment of the absolute configuration is based on a rule on the configurational course of the Ir-catalyzed allylic substitution, which was always found valid so far (ref 2).
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The assignment of the absolute configuration is based on a rule on the configurational course of the Ir-catalyzed allylic substitution, which was always found valid so far (ref 2).
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25
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79957834684
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It is very important that this compound be carefully dried (see Supporting Information).
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It is very important that this compound be carefully dried (see Supporting Information).
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26
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77950202999
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Review
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For preparation, see
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For preparation, see: Spiess, S.; Raskatov, J. A.; Gnamm, C.; Brödner, K.; Helmchen, G. Chem.-Eur. J. 2009, 15, 11087-11090
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79957849413
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The assignment of the relative configuration of 7 is tentative.
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The assignment of the relative configuration of 7 is tentative.
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79957819792
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The feasibility of Weinreb type chemistry was checked with amide 8. Upon addition of DIBAL-H at -78 °C the deacylation product, N -{(1 S)-1-[(benzyloxy)methyl]prop-2-en-1-yl}- O -methylhydroxylamine (4e ), was isolated in 96% yield.
-
The feasibility of Weinreb type chemistry was checked with amide 8. Upon addition of DIBAL-H at -78 °C the deacylation product, N -{(1 S)-1-[(benzyloxy)methyl]prop-2-en-1-yl}- O -methylhydroxylamine (4e ), was isolated in 96% yield.
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