Titanium dioxide nanoparticles induced intracellular calcium homeostasis modification in primary human keratinocytes. Towards an in vitro explanation of titanium dioxide nanoparticles toxicity

Nanotoxicology

Volumn 5, Issue 2, 2011, Pages 125-139

  Simon, Marina ^a   Barberet, Philippe ^a   Delville, Marie Hélène ^b   Moretto, Philippe ^a   Seznec, Hervé ^a  

^a CENTRE D ETUDES NUCLÉAIRES DE BORDEAUX GRADIGNAN   (France)

^b UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

calcium homeostasis; cellular imaging; cytotoxicity; nanoparticles; Titanium dioxide

Indexed keywords

CALCIUM; TITANIUM DIOXIDE;

ACCURACY; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CELL DEATH; CELL DIFFERENTIATION; CELL MEMBRANE; CELL PROLIFERATION; CELL TRANSPORT; CHEMICAL ANALYSIS; CHEMICAL MODIFICATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; KERATINOCYTE; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY;

EID: 79957818754     PISSN: 17435390     EISSN: 17435404     Source Type: Journal    
DOI: 10.3109/17435390.2010.502979     Document Type: Article

References (62)

1. Bhattacharya K, Davoren M, Boertz J, Schins RP, Hoffmann E, Dopp E. 2009. Titanium dioxide NPs induce oxidative stress and DNA-adduct formation but not DNA breakage in human lung cells. Part Fibre Toxicol 21:6-17.
2. Bernard BK, Osheroff MR, Hofmann A, Mennear JH. 1990. Toxicology and carcinogenesis studies of dietary titanium dioxidecoated mica in male and female Fischer 344 rats. J Toxicol Environ Health 29(4):417-429. (Pubitemid 20138768)
3. Berridge MJ, Bootman MD, Roderick HL. 2003. Calcium signalling: Dynamics, homeostasis and remodelling. Nat Rev Mol Cell Biol 4(7):517-529. (Pubitemid 36773404)
4. Biopixe Website. 2004. Available from: http://biopixe.free.fr/Supa-VISIO/ news.htm.
5. Brayner R. 2008. The toxicological impact of NPs. Nano Today 3:18-55.
6. Brown DM, Donaldson K, Borm PJ, Schins RP, Dehnhardt M, Gilmour P, Jimenez LA, Stone V. 2004. Calcium and ROS-mediated activation of transcription factors and TNF-a cytokine gene expression in macrophages exposed to ultrafine particles. Am J Physiol Lung Cell Mol Physiol 286:344-354.
7. Brunauer S, Emmett PH, Teller E. 1938. Adsorption of gases in multimolecular layers. J Am Chem Soc 60:309-319.
8. Bussy C, Cambedouzou J, Lanone S, Leccia E, Heresanu V, Pinault M, Mayne-L'hermite M, Brun N, Mory C, Cotte M, Doucet J, Boczkowski J, Launois P. 2008. Carbon nanotubes in macrophages: Imaging and chemical analysis by X-ray fluorescence microscopy. Nano Lett 8:2659-2663.
9. Buzea C, Blandino Pacheco II, Robbie K. 2007. Nanomaterials and NPs: Sources and toxicity. BioInterphases 2:MR17-172.
10. Carmona A, Devès G, Ortega R. 2008. Quantitative micro-analysis of metal ions in subcellular compartments of cultured dopaminergic cells by combination of three ion beam techniques. Anal Bioanal Chem 390:1585-1594.
11. Chen JL, Fayerweather WE. 1988. Epidemiologic study of workers exposed to titanium dioxide. J Occup Med 30(12):937-942. (Pubitemid 19032442)
12. Clapham DE. 2007. Calcium signaling. Cell 131:1047-1058. (Pubitemid 350258556)
13. De Jong WH, Borm PJ. 2008. Drug delivery and nanoparticles: Applications and hazards. Int J Nanomed 3:133-149. (Pubitemid 352042401)
14. Donaldson K, Seaton A. 2007. The Janus faces of NPs. J Nanosc Nanotech 7:4607-4611.
15. Donaldson K, Stone V, Clouter A, Renwick L, MacNee W. 2001. Ultrafine particles. Occup Environ Med 58:211-216.
16. Federici G, Shaw BJ, Handy RD. 2007. Toxicity of titanium dioxide NPs to rainbow trout (Oncorhynchus mykiss): Gill injury, oxidative stress, and other physiological effects. Aquat Toxicol 84:415-430. (Pubitemid 47331692)
17. Geiser M, Rothen-Rutishauser B, Kapp N, Schürch S, Kreyling W, Schulz H, Semmler M, Im Hof V, Heyder J, Gehr P. 2005. Ultrafine particles cross cellular membranes by nonphagocytic mechanisms in lungs and in cultured cells. Environ Health Perspect 113:1555-1560. (Pubitemid 41614911)
18. Griffith KJ, Chan EK, Lung CC, Hamel JC, Guo X, Miyachi K, Fritzler MJ. 1997. Molecular cloning of a novel 97-kd Golgi complex autoantigen associated with Sjögren's syndrome. Arthritis Rheum 40:1693-1702. (Pubitemid 27426164)
19. Hart GA, Hesterberg TW. 1998. In vitro toxicity of respirable-size particles of diatomaceous earth and crystalline silica compared with asbestos and titanium dioxide. J Occup Environ Med 40 (1):29-42. (Pubitemid 28092493)
20. Hilt JZ, Peppas NA. 2005. Microfabricated drug delivery devices. Int J Pharm 306:5-23.
21. International Agency for Cancer Research (IARC). Titanium dioxide (Group 2B) 2006. 93:1-4.
22. Kang SJ, Kim BM, Lee YJ, Chung HW. 2008. Titanium dioxide Nanoparticles trigger p53-mediated damage response in peripheral blood lymphocytes. Environ Mol Mutagen 49(5): 399-405.
23. Kiss B, Bíró T, Czifra G, Tóth BI, Kertész Z, Szikszai Z, Kiss AZ, Juhász I, Zouboulis CC, Hunyadi J. 2008. Investigation of micronized titanium dioxide in human skin xenografts and its effect on cellular functions of human skin-derived cells. Exp Dermatol 17:659-667. (Pubitemid 352044358)
24. Koeneman BA, Zhang Y, Westerhoff P, Chen Y, Crittenden JC, Capco DG. 2009. Toxicity and cellular responses of intestinal cells exposed to titanium dioxide. Cell Biol Toxicol 26(3): 225-238.
25. Kumar MN, Bakowsky U, Lehr C-M. 2004. Nanobiotechnology: Concepts, applications and perspectives. Niemeyer CM, Mirkin CA, Series eds. Chapter 1, New York: Wiley-VCH. pp 319-342.
26. Lai JC, Lai MB, Jandhyam S, Dukhande VV, Bhushan A, Daniels CK, Leung SW. 2008. Exposure to titanium dioxide and other metallic oxide NPs induces cytotoxicity on human neural cells fibroblasts. Int J Nanomed 3:533-545.
27. Li Q, Mahendra S, Lyon DY, Brunet L, Li MV, Liga D, Alvarez PJ. 2008. Antimicrobial nanomaterials for water disinfection and microbial control: Potential applications and implications. J Water Res 42:4591-4602.
28. Li Q, Mahendra S, Lyon DY, Brunet L, Li MV, Liga D, Alvarez PJ. 2008a. Antimicrobial nanomaterials for water disinfection and microbial control: Potential applications and implications. J Water Res 42:4591-4602.
29. Li SQ, Zhu RR, Zhu H, Xue M, Sun XY, Yao SD, Wang SL. 2008b. Nanotoxicity of TiO2 NPs to erythrocyte in vitro. Food Chem Toxicol 46:3626-3631.
30. Linkov I, Steevens J, Adlakha-Hutcheon G, Bennett E, Chappell M, Colvin V, Davis JM, Davis T, Elder A, Foss Hansen S, et al. 2009. Emerging methods and tools for environmental risk assessment, decision-making, and policy for nanomaterials: Summary of NATO Advanced Research Workshop. J Nanopart Res 11:513-527.
31. Long TC, Tajuba J, Sama P, Saleh N, Swartz C, Parker J, Hester S, Lowry GV, Veronesi B. 2007. Nanosize titanium dioxide stimulates reactive oxygen species in brain microglia and damages neurons in vitro. Environ Health Perspect 115:1631-1637.
32. Lopez-Bayghen E, Vega A, Cadena A, Granados SE, Jave, LF, Gariglio P, Alvarez-Salas LM. 1996. Transcriptional analysis of the 5′ noncoding region of the human involucrin gene. J Biol Chem 271:512-520.
33. Maxwell JA, Campbell JL, Teedsdale WJ. 1989. The Guelph PIXE software package. Nucl Instrum Meth B 43:218.
34. Missiaen L, Dode L, Vanoevelen J, Raeymaekers L, Wuytack F. 2007. Calcium in the Golgi apparatus. Cell Calcium 41:405-416. (Pubitemid 46414187)
35. Moeller R, Fritzsche W. 2006. Annual Review of Nano Research: Biosensors based on gold nanoparticules labeling [Online]; Cao G, Brinkers GJ, Series Eds. chapter 1, pp 429-466.
36. Moretto P. 1996. Nuclear microprobe: A microanalytical technique in biology. Cell Mol Biol 4:1-16.
37. Murr LE. 2006. JOM 58:23-33: http://books.google.fr/books?id= VEW8lNfQw6YC&pg=PA429&lpg=PA429&dq= Moeller+and+Fritzsche+2006+annual+review+of+nanoresearch+Biosensors+Based+on+Go ld+Nanoparticle+Labeling&source=bl&ots=kEVFbd8oQs&sig= t-G-KvuchxKfMpIFyashOjvDzrM&hl=fr&ei=XkM6TM2cDd-XOIfcrYoK&sa= X&oi=book-result&ct=result&resnum=1&ved=0CBUQ6AEwAA#v= onepage&q&f=false
38. Nohynek GJ, Dufour EK, Roberts MS. 2008. Nanotechnology, cosmetics and the skin: is there a health risk? Skin Pharmacol Physiol 21(3):136-49. (Pubitemid 351793742)
39. Oberdörster G, Oberdörster E, Oberdörster J. 2005. Nanotoxicology: An emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect 113:823-839. (Pubitemid 40984181)
40. Osano E, Kishi J, Takahashi Y. 2003. Phagocytosis of titanium particles and necrosis in TNF-a resistant mouse sarcoma L929 cells. Toxicol In Vitro17:41-47. (Pubitemid 36106490)
41. Park EJ, Yi J, Chung KH, Ryu DY, Choi J, Park K. 2008. Oxidative stress and apoptosis induced by titanium dioxide nanoparticles in cultured BEAS-2B cells. Toxicol Lett 180:222-229.
42. Pezzati R, Bossi M, Podini P, Meldolesi J, Grohovaz F. 1997. High-resolution calcium mapping of the endoplasmic reticulum-Golgi-exocytic membrane system. Electron energy loss imaging analysis of quick frozen-freeze dried PC12 cells. Mol Biol Cell. 8:1501-1512. (Pubitemid 27385572)
43. Pillai S, Bikle DD, Mancianti ML, Cline P, Hincenbergs M. 1990. Calcium regulation of growth and differentiation of normal human keratinocytes: Modulation of differentiation competence by stages of growth and extracellular calcium. J Cell Physiol 143:294-302.
44. Pioletti DP, Takei H, Kwon SY, Wood D, Sung KL. 1999. The cytotoxic effect of titanium particles phagocytosed by osteoblasts. J Biomed Mater Res 46:399-407. (Pubitemid 29293764)
45. Rahman Q, Lohani M, Dopp E, Pemsel H, Jonas L, Weiss DG, Schiffmann D. 2002. Evidence that ultrafine titanium dioxide induces micronuclei and apoptosis in Syrian hamster embryo fibroblasts. Environ Health Perspect 110:797-800.
46. Rai M, Yadav A, Gade A. 2009. Silver nanoparticles as a new generation of antimicrobials. Biotech Adv 27:76-83.
47. Sahu KK, Alex TC, Mishra D, Agrawal A. 2006. An overview on the production of pigment grade titania from titania-rich slag. Waste Manage Res 24:74-79.
48. Sayes CM, Wahi R, Kurian PA, Liu Y, West JL, Ausman KD, Warheit DB, Colvin VL. 2006. Correlating nanoscale titania structure with toxicity: A cytotoxicity and inflammatory response study with human dermal fibroblasts and human lung epithelial cells. Toxicol Sci 92:174-185. (Pubitemid 43994876)
49. Sharma P, Brown S, Walter G, Santra S, Moudgil B. 2006. Nanoparticles for bioimaging. Adv Colloid Interf Sci 123-126, 471-485. (Pubitemid 44665822)
50. ShortB, BarrFA. 2000.TheGolgi apparatus.Curr Biol 10:R583-585.
51. Silva GA. 2008. Nanotechnology approaches to crossing the blood brain barrier and drug delivery to the CNS. BMC Neurosci 9(Suppl. 3):S4.
52. Slowing II, Vivero-Escoto JL, Wu C-W, Lin VS-Y. 2008. Mesoporous silica NPs as controlled release drug delivery and gen transfection carriers. Adv Drug Deliv Rev 60:1278-1288.
53. Sounderya N, Zhang Y. 2008. Use of core/shell structured NPs for biomedical applications. Recent Patents on Biomed Engineer 1:34-42.
54. Stevens MM, George JH. 2005. Exploring and engineering the cell surface interface. Science 310:1135-1138. (Pubitemid 41681731)
55. Vasioukhin V, Bauer C, Yin M, Fuchs E. 2000. Directed actin polymerization is the driving force for epithelial cell-cell adhesion. Cell 100:209-219. (Pubitemid 30064909)
56. Vevers WF, Jha AN. 2008. Genotoxic and cytotoxic potential of titanium dioxide (TiO2) NPs on fish cells in vitro. Ecotoxicology 1:410-420.
57. Wang F, Tan WB, Zhang Y, Fan X, Wang M. 2006. Luminescent nanomaterials for biological labeling. Nanotechnology 17:R1-13.
58. Wang JJ, Sanderson BJ, Wang H. 2007. Cyto- and genotoxicity of ultrafine TiO2 particles in cultured human lymphoblastoid cells. Mutat Res 628:99-106. (Pubitemid 46330879)
59. Warheit DB, Webb TR, Sayes CM, Colvin VL, Reed KL. 2006. Pulmonary instillation studies with nanoscale TiO2 rods and dots in rats: Toxicity is not dependent upon particle size and surface area. Toxicol Sci 91:227-236.
60. Watt FM, Phil D. 1983. Involucrin and other markers of keratinocyte terminal differentiation. J Invest Dermatol 81:100s-103s. (Pubitemid 13030423)
61. Xia T, Kovochich M, Brant J, Hotze M, Sempf J, Oberley T, Sioutas C, Yeh JI, Wiesner MR, Nel AE. 2006. Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm. Nano Lett 6:1794-1807. (Pubitemid 44327550)
62. Zamansky GB, Nguyen U, Chou I-N. 1991. An immunofluorescence study of the calcium-induced coordinated reorganization of microfilaments, keratin intermediate filaments and microtubules in cultured human epidermal keratinocytes. J Invest Dermatol 97:985-994.