Phosphatidylcholine for the treatment of prominent lower eyelid fat pads: A pilot study

Ophthalmic Plastic and Reconstructive Surgery

Volumn 27, Issue 3, 2011, Pages 147-151

  Tawfik, Hatem A ^a,d   Zuel Fakkar, Nehal ^b   Elmarasy, Rehab ^b   Talib, NorLaila ^c   Elsamkary, Mahmoud ^a   Abdallah, Mahmoud A ^b  

^a AIN SHAMS UNIVERSITY   (Egypt)

^b AIN SHAMS UNIVERSITY   (Egypt)

^c Selayang Hospital   (Malaysia)

^d NONE   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOSTABIL; PLACEBO;

ADIPOSE TISSUE; ADULT; AGED; ARTICLE; BURNING SENSATION; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; ESTHETICS; EYE PAIN; EYELID; EYELID EDEMA; EYELID FAT PAD; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; MESOTHERAPY; NORMAL HUMAN; OFF LABEL DRUG USE; PATIENT SATISFACTION; PILOT STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

ADIPOSE TISSUE; ADULT; AGED; DOUBLE-BLIND METHOD; EYELID DISEASES; FAT EMULSIONS, INTRAVENOUS; FEMALE; FOLLOW-UP STUDIES; HUMANS; LIPOLYSIS; MALE; MESOTHERAPY; MIDDLE AGED; OFF-LABEL USE; PATIENT SATISFACTION; PHOSPHATIDYLCHOLINES; PILOT PROJECTS; QUESTIONNAIRES;

EID: 79957805945     PISSN: 07409303     EISSN: 15372677     Source Type: Journal    
DOI: 10.1097/IOP.0b013e3181cc8582     Document Type: Article

References (35)

1. Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80.
2. Mesotherapyworldwide. Available at: http://www.mesotherapyworldwide.com/ images/pdf/LIPOSTABILINJECTIONTECHNIQUE.pdf. Accessed January 1, 2009.
3. Salti G, Ghersetich I, Tantussi F, et al. Phosphatidylcholine and sodium deoxycholate in the treatment of localized fat: a double-blind, randomized study. Dermatol Surg 2008;34:60-6; discussion 66. (Pubitemid 350308587)
4. Kopera D, Horejsi R, Werner S, Moeller R. Injection lipolysis for reduction of saddlebag trochanteric bulges-half-side controlled pilot study. J Dtsch Dermatol Ges 2008;6:287-90.
5. Kopera D, Binder B, Toplak H. Intralesional lipolysis with phosphatidylcholine for the treatment of lipomas: pilot study. Arch Dermatol 2006;142:395-6.
6. Park SH, Kim DW, Lee MA, et al. Effectiveness of mesotherapy on body contouring. Plast Reconstr Surg 2008;121:179e-85e. (Pubitemid 351653245)
7. Co AC, Abad-Casintahan MF, Espinoza-Thaebtharm A. Submental fat reduction by mesotherapy using phosphatidylcholine alone vs. phosphatidylcholine and organic silicium: a pilot study. J Cosmet Dermatol 2007;6:250-7. (Pubitemid 350214883)
8. Atiyeh BS, Ibrahim AE, Dibo SA. Cosmetic mesotherapy: between scientific evidence, science fiction, and lucrative business. Aesthetic Plast Surg 2008;32:842-9.
9. Rotunda AM, Ablon G, Kolodney MS. Lipomas treated with subcutaneous deoxycholate injections. J Am Acad Dermatol 2005;53:973-8. (Pubitemid 41677322)
10. Lim EC, Seet RC. Botulinum toxin injections to reduce adiposity: possibility, or fat chance? Med Hypotheses 2006;67:1086-9. (Pubitemid 44302234)
11. Caruso MK, Roberts AT, Bissoon L, et al. An evaluation of mesotherapy solutions for inducing lipolysis and treating cellulite. J Plast Reconstr Aesthet Surg 2008;61:1321-4.
12. Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
13. Young VL. Lipostabil: the effect of phosphatidylcholine on subcutaneous fat. Aesthet Surg J 2003;23:413-7. (Pubitemid 37407064)
14. Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. (Pubitemid 38076368)
15. Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. (Pubitemid 32290868)
16. Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. J Cosmet Dermatol 2005;4:308-13.
17. Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7; discussion 428. (Pubitemid 38524165)
18. Duncan DI, Chubaty R. Clinical safety data and standards of practice for injection lipolysis: a retrospective study. Aesthet Surg J 2006;26:575-85. (Pubitemid 44649136)
19. Hasengschwandtner F. Injection lipolysis for effective reduction of localized fat in place of minor surgical lipoplasty. Aesthet Surg J 2006;26:125-30.
20. Uygur F, Evinç R, Duman H. Is phosphatidylcholine harmful to the peripheral neural tissue? An experimental study in rats. Aesthet Surg J 2008;28:663-7.
21. Duncan DI, Hasengschwandtner F. Lipodissolve for subcutaneous fat reduction and skin retraction. Aesthet Surg J 2005;25:530-43. (Pubitemid 41574461)
22. Gryskiewicz JM, Adams WP Jr. Orlando 2006: plastic surgeons rate the "Hot Topics." Aesthetic Surg J 2006;26:479-84.
23. ASPS Guiding Principles for Mesotherapy/Injection Lipolysis. Available at: http://www.plasticsurgery.org/. Accessed July 5, 2008.
24. ® not licensed for cosmetic use. MHRA press Release 13.7.2005. Available at: http://www.mhra.gov. uk/Aboutus/index.htm. Accessed July 7, 2007.
25. ®-Questions and Answers. Available at: http://www.mhra.gov. uk/Aboutus/index.htm. Accessed July 7, 2007.
26. Treacy PJ, Goldberg DJ. Use of phosphatidylcholine for the correction of lower lid bulging due to prominent fat pads. J Cosmet Laser Ther 2006;8:129-32. (Pubitemid 44395593)
27. Bechara FG, Sand M, Hoffmann K, et al. Fat tissue after lipolysis of lipomas: a histopathological and immunohistochemical study. J Cutan Pathol 2007;34:552-7. (Pubitemid 46920255)
28. Cabbabe EB. To lipodissolve or not? Mol Med 2007;104:384-6.
29. Moro C, Pillar F, de Glisezinski I, et al. Exercise-induced lipid mobilization in subcutaneous adipose tissue is mainly related to natriuretic peptides in overweight men. Am J Physiol Endocrinol Metab 2008;295:505-13.
30. Danilovic DL, Bloise W, Knobel M. Factitious thyrotoxicosis induced by mesotherapy: a case report. Thyroid 2008;18:655-7. (Pubitemid 351918444)
31. Davis MD, Wright TI, Shehan JM. A complication of mesotherapy: noninfectious granulomatous panniculitis. Arch Dermatol 2008;144:808-9. (Pubitemid 351846891)
32. Strahan JE, Cohen JL, Chorny JA. Granuloma annulare as a complication of mesotherapy: a case report. Dermatol Surg 2008;34:836-8. (Pubitemid 351792304)
33. Munayco CV, Grijalva CG, Culqui DR, et al. Outbreak of persistent cutaneous abscesses due to mycobacterium chelonae after mesotherapy sessions. Rev Saude Publica 2008;42:146-9.
34. Sañudo A, Vallejo F, Sierra M, et al. Nontuberculous mycobacteria infection after mesotherapy: preliminary report of 15 cases. Int J Dermatol 2007;46:649-53. (Pubitemid 46909413)
35. Nabavi CB, Minckler DS, Tao JP. Histologic features of mesotherapyinduced orbital fat inflammation. Ophthal Plast Reconstr Surg 2009;25:69-70.