Cosmetic mesotherapy: Between scientific evidence, science fiction, and lucrative business

Aesthetic Plastic Surgery

Volumn 32, Issue 6, 2008, Pages 842-849

  Atiyeh, Bishara S ^a   Ibrahim, Amir E ^a   Dibo, Saad A ^a  

^a AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

Author keywords

Facial rejuvenation; Lipolysis; Mesotherapy

Indexed keywords

PHOSPHATIDYLCHOLINE;

ALLERGIC REACTION; BACTERIAL INFECTION; DERMATOLOGICAL PROCEDURES; HEMATOMA; LICHENOID; LIPOLYSIS; MESOTHERAPY; NECROSIS; PRIORITY JOURNAL; PSORIASIS; REJUVENATION; REVIEW; SAFETY; STANDARDIZATION; ULCER; URTICARIA;

AGED; AGING; AMBULATORY CARE; COSMETIC TECHNIQUES; ESTHETICS; FAT EMULSIONS, INTRAVENOUS; FEMALE; HUMANS; INJECTIONS, SUBCUTANEOUS; LEBANON; LIPECTOMY; MALE; MIDDLE AGED; PHOSPHATIDYLCHOLINES; REJUVENATION; RISK ASSESSMENT; SKIN AGING;

EID: 55349121828     PISSN: 0364216X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00266-008-9195-x     Document Type: Review

References (55)

1. Mesotherapy. Wikipedia, the free encyclopedia. Available at http://en.wikipedia.org/wiki/Mesotherapy. Accessed 10 February 2008
2. PG Rittes 2001 The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads Dermatol Surg 27 391 392
3. E Nagore P Ramos R Botella-Estrada JA Ramos-Níguez O Sanmartín P Castejón 2001 Cutaneous infection with Mycobacterium fortuitum after localized microinjections (mesotherapy) treated successfully with a triple drug regimen Acta Derm Venereol 81 291 293
4. G Micali F Lacarrubba A Tedeschi R Nodstrom 2008 Mesotherapy for rejuvenation of photoaged skin: Ultrasound evaluation J Am Acad Dermatol 58 AB23
5. A Rotunda MS Kolodney 2006 Mesotherapy and phosphatidylcholine injections: historical clarification and review Dermatol Surg 32 465 480
6. Mesotherapie and Estetik. Available at http://www.mesotherapy.com/faq/. Accessed 11 February 2008
7. Mesotherapy domains: Mesotherapy, the 'safer' way to slimming down. Available at http://www.mesotherapydomains.com/mesotherapy.html. Accessed 10 February 2008
8. S Brown 2006 The science of mesotherapy: Chemical anarchy Aesthetic Surg J 26 95 98
9. L Tanrikulu 2007 Mesotherapy: Medical education Turk Klinikleri J Med Sci 27 272 275
10. A Kalil 2006 Aesthetic mesotherapy: The US approach and contribution Cosmet Dermatol 19 753 758
11. AM Rotunda MM Avram A Avram 2005 Cellulite: is there a role for injectable? J Cosmet Laser Ther 7 147 154
12. TD Doerr 2007 Lipoplasty of the face and neck Curr Opin Otolaryngol Head Neck Surg 15 228 232
13. MY Seon BC Yong JA Kyu 2005 A case of panniculitis following mesotherapy Korean J Dermatol 43 431 433
14. A Matarasso TM Pfeiffer the Plastic Surgery Educational Foundation DATA Committee 2005 Mesotherapy for body contouring Plast Reconstr Surg 115 1420 1424
15. J Stachowski K Botts L Rine D Kato J Pollock 2006 Mesotherapy: Cosmetic applications Int J Pharmaceut Compound 10 331 334
16. Caruso MK, Roberts AT, Bissoon L, Self KS, Guillot TS, Greenway FL (2007) An evaluation of mesotherapy solutions for inducing lipolysis and treating cellulite. J Plast Reconstr Aesthet Surg October 20. doi: 10.1016/j.bjps.2007. 03.039. (Epub ahead of print)
17. R Bryant 2004 Controversial mesotherapy: could it be the next Botox? Dermatol Times 25 1
18. N Lawrence 2003 Commentary: no smoking gun: findings from a national survey of office-based cosmetic surgery adverse event reporting Dermatol Surg 29 1099
19. M Tonkovic-Capin CC Riddle ES Schweiger DJ Aires SH Manson V Tonkovic-Capin 2007 Brief discussion: medicolegal aspects of consent and checklists for common cosmetic procedures Cosmet Dermatol 20 5 291 294
20. RJ Rohrich 2005 Mesotherapy: what is it? does it work? Plast Reconstr Surg 115 1425
21. G Salti I Ghersetich F Tantussi B Bovani T Lotti 2008 Phosphatidylcholine and sodium deoxycholate in thetreatment of localized fat: a double-blind, randomized study Dermatol Surg 34 60 66
22. JB Prins S O'Rahilly 1997 Regulation of adipose cell number in man Clin Sci 92 3 11
23. C Londos DL Brasaemle CJ Schultz DC Adler-Wailes DM Levin AR Kimmel CM Rondinone 1999 On the control of lipolysis in adipocytes Ann N Y Acad Sci 892 155 168
24. JM Gryskiewicz WP Adams Jr 2006 Plastic surgeons rate the "hot topics" Aesthetic Surg J 26 479 484
25. PG Rittes JC Rittes MF Carriel Amary 2006 Injection of phosphatidylcholine in fat tissue: experimental study of local action in rabbits Aesthetic Plast Surg 30 474 478
26. FL Greenway GA Bray D Heber 1995 Topical fat reduction Obes Res 3 Suppl 4 561S 568S
27. M Kolehmainen JJ Ohisalo JM Kaartinen V Tuononen M Pääkkö nen E Poikolainen E Alhava MI Uusitupa 2000 Concordance of in vivo microdialysis and in vitro techniques in the studies of adipose tissue metabolism Int J Obes Relat Metab Disord 24 1426 1432
28. R Aicher 2003 Cosmetic surgery and the law The American Society for Aesthetic Plastic Surgery. Aesthetic Soc News 7 11
29. C Brandão N Fernandes N Mesquita M Dinis-Ribeiro R Silva HL Viana LM Dias 2005 Abdominal haematoma - a mesotherapy complication Acta Derm Venereol 85 446
30. M Rosenbaum V Prieto J Hellmer M Boschmann J Krueger RL Leibel AG Ship 1998 An exploratory investigation of the morphology and biochemistry of cellulite Plast Reconstr Surg 101 1934 1939
31. VL Young 2003 Lipostabil: the effect of phosphatidylcholine on subcutaneous fat Aesthetic Surg J 23 413 417
32. American Society for Dermatologic Surgery (January 2006) Technology report: mesotherapy. Available at http://www.asds.net/ TechnologyReportMesotherapy.aspx. Accessed 15 February 2008
33. S Amin R Phelps D Goldberg 2006 Mesotherapy for facial skin rejuvenation: a clinical, histologic, and electron microscopic evaluation Dermatol Surg 32 12 1467 1472
34. Serra M, Pereira FB (2002) Subcutaneous infiltration with phosphatidylcholine solution for treatment of buffalo hump and fatty pads. In: Program and abstracts of the 3rd International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV. Athens, Greece, October 23-26, 2001, vol 6, pp 75-76
35. PT Rose M Morgan 2005 Histological changes associated with mesotherapy for fat dissolution J Cosmet Laser Ther 7 17 19
36. DI Duncan F Hasengschwandtner B Leonfelden 2005 Lipodissolve for subcutaneous fat reduction and skin retraction Aesthetic Surg J 25 530 543
37. D Hexsel M Serra R Mazzuco T Dal'Forno D Zechmeister 2003 Phosphatidylcholine in the treatment of localized fat J Drugs Dermatol 2 511 518
38. K Singh 2006 Nonsurgical facial rejuvenation J Int Med Sci Acad 19 158 164
39. M Vedamurthy 2007 Mesotherapy Indian J Dermatol Venereol Leprol 73 60 62
40. Edwards DA (2004) Bio Health Center. Available at www.biohealthcenter. com/wrinkles.html. Accessed 10 February 2008
41. E Nagore P Ramos R Botella-Estrada JA Ramos-Níguez O Sanmartín P Castejón 2001 Cutaneous infection with Mycobacterium fortuitum after localized microinjections (mesotherapy) treated successfully with a triple drug regimen Acta Derm Venereol 81 291 293
42. DP Lee SE Chang 2005 Subcutaneous nodules showing fat necrosis owing to mesotherapy Dermatol Surg 3 250 251
43. D Bessis JJ Guilhou B Guillot 2004 Localized urticaria pigmentosa triggered by mesotherapy Dermatology 209 343 344
44. J Tan B Rao 2006 Mesotherapy-induced panniculitis treated with dapsone: case report and review of reported adverse effects of mesotherapy J Cutan Med Surg 10 92 95
45. P Rosina C Chieregato D Miccolis FS D'Onghia 2001 Psoriasis and side-effects of mesotherapy Int J Dermatol 40 581 583
46. F Henry C Piérard-Franchimont GE Piérard 2005 Clinical case of the month. Atypical mycobacteria and mesotherapy Rev Med Liege 60 7 10
47. M Colón-Soto RA Peredo LM Vilá 2006 Systemic lupus erythematosus after mesotherapy with acetyl-L-carnitine J Clin Rheumatol 12 261 262
48. W Furlong BA Cunanan LA Weymouth JL Pearson DC Sockwell SR Jenkins J Marr M Tipple DD Shah D Blythe GR Lum JO Davies-Cole A Srinivasan E Meites RH Sunenshine 2005 Outbreak of mesotherapy-associated skin reactions-District of Columbia area, January-February 2005 MMWR Morb Mortal Wkly Rep 54 1127 1130
49. A Sañudo F Vallejo M Sierra JG Hoyos S Yepes JC Wolff LA Correa C Montealegre P Navarro E Bedoya G Sanclemente 2007 Nontuberculous mycobacteria infection after mesotherapy: Preliminary report of 15 cases Int J Dermatol 46 649 653
50. ASPS/PSEF (2005) Mesotherapy not proven as a safe alternative to liposuction: plastic surgeons caution against unknown dangers, April 18, 2005. Available at www.plasticsurgery.org/media/press_releases/Mesotherapy-Not-Proven- As-A-Safe-Alternative-To-Liposuction.cfm. Accessed 10 February 2008
51. ASPS/PSEF (2007) Non-invasive fat-melting procedures - hype or reality? Emerging trends discussed at American Society of Plastic Surgeons Annual Meeting, October 27, 2007. Available at www.plasticsurgery.org/media/ press_releases/Non-Invasive-Fat-Melting-Procedures-Hype-or-Reality.cfm. Accessed 15 February 2008
52. RJ Rohrich EJ Janis NR Reisman 2003 Use of off-label and non-approved drugs and devices in plastic surgery Plast Reconstr Surg 112 241 243
53. American Society of Plastic Surgeons (2005) Policy statement: mesotherapy. Available at www.plasticsurgery.org/medical_professionals/ Policy_Statements/loader.cfm?url=/commonspot/security/getfile.cfm&PageID= 16075. Accessed 11 February 2008
54. Donofrio LM (2007) Mesotherapy. Cosmet Dermatol 20:97-98
55. IA Rivera-Olivero A Guevara A Escalona M Oliver R Pérez-Alfonzo J Piquero O Zerpa JH de Waard 2006 Soft tissue infections due to non-tuberculous mycobacteria following mesotherapy. What is the price of beauty? Enferm Infecc Microbiol Clin 24 302 306