Selective labeling and monitoring pH changes of lysosomes in living cells with fluorogenic pH sensors

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 12, 2011, Pages 3546-3549

  Ying, Lai Qiang ^a   Branchaud, Bruce P ^a  

^a Life Technologies   (United States)

Author keywords

Cell imaging; Confocal microscopy; Fluorescent probe; Lysosome; pH sensor

Indexed keywords

ARTICLE; BIOSENSOR; CELL MEMBRANE PERMEABILITY; CELL PH; CONCENTRATION (PARAMETERS); FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; LYSOSOME; MOLECULAR PROBE; PH;

ACID-BASE EQUILIBRIUM; ANIMALS; BORON COMPOUNDS; CATTLE; CELL LINE; FLOW CYTOMETRY; FLUORESCENT DYES; HYDROGEN-ION CONCENTRATION; LYSOSOMES; MICROSCOPY, CONFOCAL; MODELS, BIOLOGICAL; MOLECULAR STRUCTURE;

EID: 79957791722     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.04.137     Document Type: Article

References (25)

1. Rich, I. N.; Brackmann, I.; Worthington-White, D.; Dewey, M. J. J. Cell Physiol. 1998, 177, 109.
2. Perez-Sala, D.; Collado-Escobar, D.; Mollinedo, F. J. Biol. Chem. 1995, 270, 6235.
3. Skowronski, E.; Babior, B. M. Proc. Natl. Acad. Sci. U.S.A. 1996, 93, 654.
4. Ishaque, A.; Al-Rubeai, M. J. Immunol. Methods 1998, 221, 43.
5. Meisenholder, G. W.; Martin, S. J.; Green, D. R.; Nordberg, J.; Babior, B. M.; Gottlieb, R. A. J. Biol. Chem. 1996, 271, 16260.
6. Miksa, M.; Komura, H.; Wu, R.; Shah, K. G.; Wang, P. J. Immunol. Methods 2009, 342, 71.
7. Overly, C. C.; Lee, K. D.; Berthiaume, E.; Hollenbeck, P. J. Proc. Natl. Acad. Sci. U.S.A. 1995, 92, 3156.
8. Lakadamyali, M.; Rust, M. J.; Babcock, H. P.; Zhuang, X. Proc. Natl. Acad. Sci. U.S.A. 2003, 100, 9280.
9. Adie, E. J.; Kalinka, S.; Smith, L.; Francis, M. J.; Marenghi, A.; Cooper, M. E.; Briggs, M.; Michael, N. P.; Milligan, G.; Game, S. Biotechniques 2002, 33, 1152.
10. Izumi, H.; Torigoe, T.; Ishiguchi, H.; Uramoto, H.; Yoshida, Y.; Tanabe, M.; Ise, T.; Murakami, T.; Yoshida, T.; Nomoto, M.; Kohno, K. Cancer Treatment Rev. 2003, 29, 541.
11. Davies, T. A.; Fine, R. E.; Johnson, R. J.; Levesque, C. A.; Rathbun, W. H.; Seetoo, K. F.; Smith, S. J.; Strohmeier, G.; Volicer, L. Biochem. Biophys. Res. Commun. 1993, 194, 537.
12. Ohkuma, S.; Poole, B. Proc. Natl. Acad. Sci. U.S.A. 1978, 75, 3327.
13. Schindler, M.; Grabski, S.; Hoff, E.; Simon, S. Biochemistry 1996, 35, 2811.
14. Han, J.; Burgess, K. Chem. Rev. 2010, 110, 2709.
15. Beletskii, A.; Cooper, M.; Sriraman, P.; Chiriac, C.; Zhao, L.; Abbot, S.; Yu, L. Biotechniques 2005, 39, 894.
16. Glunde, K.; Foss, C. A.; Takagi, T.; Wildes, F.; Bhujwalla, Z. M. Bioconjug. Chem. 2005, 16, 843.
17. Nilsson, C.; Johansson, U.; Johansson, A. C.; Kagedal, K.; Ollinger, K. Apoptosis 2006, 11, 1149.
18. Nilsson, C.; Kagedal, K.; Johansson, U.; Ollinger, K. Methods Cell. Sci. 2003, 25, 185.
19. Peng, J.; He, X.; Wang, K.; Tan, W.; Wang, Y.; Liu, Y. Anal. Bioanal. Chem. 2007, 388, 645.
20. Albertazzi, L.; Storti, B.; Marchetti, L.; Beltram, F. J. Am. Chem. Soc. 2010, 132, 18158.
21. For example, Life Technologies has commercialized a variety of LysoSensor probes (e.g., Yellow/Blue DND-160, Blue DND-167, Green DND-189, Green DND-153) for selective labeling of lysosomes in living cells.
22. Urano, Y.; Asanuma, D.; Hama, Y.; Koyama, Y.; Barrett, T.; Kamiya, M.; Nagano, T.; Watanabe, T.; Hasegawa, A.; Choyke, P. L.; Kobayashi, H. Nat. Med. 2008, 15, 104.
23. Ozlem, S.; Akkaya, E. U. J. Am. Chem. Soc. 2009, 131, 48.
24. Gunnlaugsson, T.; Ali, H. D.; Glynn, M.; Kruger, P. E.; Hussey, G. M.; Pfeffer, F. M.; dos Santos, C. M.; Tierney, J. J. Fluoresc. 2005, 15, 287.
25. Ji, J.; Rosenzweig, N.; Griffin, C.; Rosenzweig, Z. Anal. Chem. 2000, 72, 3497.