-
1
-
-
4644252335
-
Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: An updated meta-analysis
-
Thirion P, Michiels S, Pignon JP, Buyse M, Braud AC, Carlson RW, O'Connell M, Sargent P, Piedbois P. Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: an updated meta-analysis. J Clin Oncol 2004; 22: 3766-3775
-
(2004)
J Clin Oncol
, vol.22
, pp. 3766-3775
-
-
Thirion, P.1
Michiels, S.2
Pignon, J.P.3
Buyse, M.4
Braud, A.C.5
Carlson, R.W.6
O'Connell, M.7
Sargent, P.8
Piedbois, P.9
-
2
-
-
0031858552
-
Antitumor activities of a novel fluoropyrimidine, N4pentyloxycarbonyl- 5′-deoxy-5-fluorocytidine (capecitabine)
-
Ishikawa T, Fukase Y, Yamamoto T, Sekiguchi F, Ishitsuka H. Antitumor activities of a novel fluoropyrimidine, N4pentyloxycarbonyl- 5′-deoxy-5-fluorocytidine (capecitabine). Biol Pharm Bull 1998; 21: 713-717
-
(1998)
Biol Pharm Bull
, vol.21
, pp. 713-717
-
-
Ishikawa, T.1
Fukase, Y.2
Yamamoto, T.3
Sekiguchi, F.4
Ishitsuka, H.5
-
3
-
-
0344541873
-
Tumor selective delivery of 5-fluorouracil by capecitabine, a new oral fluoropyrimidine carbamate, in human cancer xenografts
-
Ishikawa T, Utoh M, Sawada N, Nishida M, Fukase Y, Sekiguchi F, Ishitsuka H. Tumor selective delivery of 5-fluorouracil by capecitabine, a new oral fluoropyrimidine carbamate, in human cancer xenografts. Biochem Pharmacol 1998; 55: 1091-1097
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 1091-1097
-
-
Ishikawa, T.1
Utoh, M.2
Sawada, N.3
Nishida, M.4
Fukase, Y.5
Sekiguchi, F.6
Ishitsuka, H.7
-
4
-
-
0032127244
-
Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue
-
Miwa M, Ura M, Nishida M, Sawada N, Ishikawa T, Mori K, Shimma N, Umeda I, Ishitsuka H. Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue. Eur J Cancer 1998; 34: 1274-1281
-
(1998)
Eur J Cancer
, vol.34
, pp. 1274-1281
-
-
Miwa, M.1
Ura, M.2
Nishida, M.3
Sawada, N.4
Ishikawa, T.5
Mori, K.6
Shimma, N.7
Umeda, I.8
Ishitsuka, H.9
-
5
-
-
0036235128
-
First-line oral capecitabine therapy in metastatic colorectal cancer: A favorable safety profile compared with intravenous 5-fluorouracil/ leucovorin
-
Cassidy J, Twelves C, Van Cutsem E, Hoff P, Bajetta E, Boyer M, Bugat R, Burger U, Garin A, Graeven U, McKendric J, Maroun J, Marshall J, Osterwalder B, Perez-Manga G, Rosso R, Rougier P, Schilsky RL. First-line oral capecitabine therapy in metastatic colorectal cancer: a favorable safety profile compared with intravenous 5-fluorouracil/ leucovorin. Ann Oncol 2002; 13: 566-575
-
(2002)
Ann Oncol
, vol.13
, pp. 566-575
-
-
Cassidy, J.1
Twelves, C.2
Van Cutsem, E.3
Hoff, P.4
Bajetta, E.5
Boyer, M.6
Bugat, R.7
Burger, U.8
Garin, A.9
Graeven, U.10
McKendric, J.11
Maroun, J.12
Marshall, J.13
Osterwalder, B.14
Perez-Manga, G.15
Rosso, R.16
Rougier, P.17
Schilsky, R.L.18
-
6
-
-
0035871538
-
Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer: Results of a randomized phase III study
-
Hoff PM, Ansari R, Batist G, Cox J, Kocha W, Kuperminc M, Maroun J, Walde D, Weaver C, Harrison E, Burger HU, Osterwalder B, Wong AO, Wong R. Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer: results of a randomized phase III study. J Clin Oncol 2001; 19: 2282-2292
-
(2001)
J Clin Oncol
, vol.19
, pp. 2282-2292
-
-
Hoff, P.M.1
Ansari, R.2
Batist, G.3
Cox, J.4
Kocha, W.5
Kuperminc, M.6
Maroun, J.7
Walde, D.8
Weaver, C.9
Harrison, E.10
Burger, H.U.11
Osterwalder, B.12
Wong, A.O.13
Wong, R.14
-
7
-
-
11144354462
-
Oral capecitabine vs intravenous 5-fluorouracil and leucovorin: Integrated efficacy data and novel analyses from two large, randomised, phase III trials
-
Van Cutsem E, Hoff PM, Harper P, Bukowski RM, Cunningham D, Dufour P, Graeven U, Lokich J, Madajewicz S, Maroun JA, Marshall JL, Mitchell EP, Perez-Manga G, Rougier P, Schmiegel W, Schoelmerich J, Sobrero A, Schilsky RL. Oral capecitabine vs intravenous 5-fluorouracil and leucovorin: integrated efficacy data and novel analyses from two large, randomised, phase III trials. Br J Cancer 2004; 90: 1190-1197
-
(2004)
Br J Cancer
, vol.90
, pp. 1190-1197
-
-
Van Cutsem, E.1
Hoff, P.M.2
Harper, P.3
Bukowski, R.M.4
Cunningham, D.5
Dufour, P.6
Graeven, U.7
Lokich, J.8
Madajewicz, S.9
Maroun, J.A.10
Marshall, J.L.11
Mitchell, E.P.12
Perez-Manga, G.13
Rougier, P.14
Schmiegel, W.15
Schoelmerich, J.16
Sobrero, A.17
Schilsky, R.L.18
-
8
-
-
0035503151
-
Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: Results of a large phase III study
-
Van Cutsem E, Twelves C, Cassidy J, Allman D, Bajetta E, Boyer M, Bugat R, Findlay M, Frings S, Jahn M, McKendrick J, Osterwalder B, Perez-Manga G, Rosso R, Rougier P, Schmiegel WH, Seitz JF, Thompson P, Vieitez JM, Weitzel C, Harper P. Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: results of a large phase III study. J Clin Oncol 2001; 19: 4097-4106
-
(2001)
J Clin Oncol
, vol.19
, pp. 4097-4106
-
-
Van Cutsem, E.1
Twelves, C.2
Cassidy, J.3
Allman, D.4
Bajetta, E.5
Boyer, M.6
Bugat, R.7
Findlay, M.8
Frings, S.9
Jahn, M.10
McKendrick, J.11
Osterwalder, B.12
Perez-Manga, G.13
Rosso, R.14
Rougier, P.15
Schmiegel, W.H.16
Seitz, J.F.17
Thompson, P.18
Vieitez, J.M.19
Weitzel, C.20
Harper, P.21
more..
-
9
-
-
0031017851
-
Patient preferences for oral versus intravenous palliative chemotherapy
-
Liu G, Franssen E, Fitch MI, Warner E. Patient preferences for oral versus intravenous palliative chemotherapy. J Clin Oncol 1997; 15: 110-115
-
(1997)
J Clin Oncol
, vol.15
, pp. 110-115
-
-
Liu, G.1
Franssen, E.2
Fitch, M.I.3
Warner, E.4
-
10
-
-
0031307611
-
Patient preferences for chemotherapy schedules used in the treatment of advanced colorectal cancer - a pilot study
-
Topham C, Moore J. Patient preferences for chemotherapy schedules used in the treatment of advanced colorectal cancer - a pilot study. Eur J Cancer Care (Engl) 1997; 6: 291-294
-
(1997)
Eur J Cancer Care (Engl)
, vol.6
, pp. 291-294
-
-
Topham, C.1
Moore, J.2
-
11
-
-
0033874892
-
Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
-
de Gramont A, Figer A, Seymour M, Homerin M, Hmissi A, Cassidy J, Boni C, Cortes-Funes H, Cervantes A, Freyer G, Papamichael D, Le Bail N, Louvet C, Hendler D, de Braud F, Wilson C, Morvan F, Bonetti A. Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol 2000; 18: 2938-2947
-
(2000)
J Clin Oncol
, vol.18
, pp. 2938-2947
-
-
de Gramont, A.1
Figer, A.2
Seymour, M.3
Homerin, M.4
Hmissi, A.5
Cassidy, J.6
Boni, C.7
Cortes-Funes, H.8
Cervantes, A.9
Freyer, G.10
Papamichael, D.11
Le Bail, N.12
Louvet, C.13
Hendler, D.14
de Braud, F.15
Wilson, C.16
Morvan, F.17
Bonetti, A.18
-
12
-
-
0034712536
-
Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: A multicentre randomised trial
-
Douillard JY, Cunningham D, Roth AD, Navarro M, James RD, Karasek P, Jandik P, Iveson T, Carmichael J, Alakl M, Gruia G, Awad L, Rougier P. Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial. Lancet 2000; 355: 1041-1047
-
(2000)
Lancet
, vol.355
, pp. 1041-1047
-
-
Douillard, J.Y.1
Cunningham, D.2
Roth, A.D.3
Navarro, M.4
James, R.D.5
Karasek, P.6
Jandik, P.7
Iveson, T.8
Carmichael, J.9
Alakl, M.10
Gruia, G.11
Awad, L.12
Rougier, P.13
-
13
-
-
0034727063
-
Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group
-
Saltz LB, Cox JV, Blanke C, Rosen LS, Fehrenbacher L, Moore MJ, Maroun JA, Ackland SP, Locker PK, Pirotta N, Elfring GL, Miller LL. Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group. N Engl J Med 2000; 343: 905-914
-
(2000)
N Engl J Med
, vol.343
, pp. 905-914
-
-
Saltz, L.B.1
Cox, J.V.2
Blanke, C.3
Rosen, L.S.4
Fehrenbacher, L.5
Moore, M.J.6
Maroun, J.A.7
Ackland, S.P.8
Locker, P.K.9
Pirotta, N.10
Elfring, G.L.11
Miller, L.L.12
-
14
-
-
24644432555
-
-
Kohne CH, van Cutsem E, Wils J, Bokemeyer C, El-Serafi M, Lutz MP, Lorenz M, Reichardt P, Ruckle-Lanz H, Frickhofen N, Fuchs R, Mergenthaler HG, Langenbuch T, Vanhoefer U, Rougier P, Voigtmann R, Muller L, Genicot B, Anak O, Nordlinger B. Phase III study of weekly high-dose infusional fluorouracil plus folinic acid with or without irinotecan in patients with metastatic colorectal cancer: European Organisation for Research and Treatment of Cancer Gastrointestinal Group Study 40986. J Clin Oncol 2005; 23: 4856-4865
-
Kohne CH, van Cutsem E, Wils J, Bokemeyer C, El-Serafi M, Lutz MP, Lorenz M, Reichardt P, Ruckle-Lanz H, Frickhofen N, Fuchs R, Mergenthaler HG, Langenbuch T, Vanhoefer U, Rougier P, Voigtmann R, Muller L, Genicot B, Anak O, Nordlinger B. Phase III study of weekly high-dose infusional fluorouracil plus folinic acid with or without irinotecan in patients with metastatic colorectal cancer: European Organisation for Research and Treatment of Cancer Gastrointestinal Group Study 40986. J Clin Oncol 2005; 23: 4856-4865
-
-
-
-
15
-
-
0037271431
-
Safety and efficacy of outpatient treatment with CPT-11 plus bolus folinic acid/5-fluorouracil as first-line chemotherapy for metastatic colorectal cancer
-
Moehler M, Hoffmann T, Zanke C, Hohl H, Burg H, Ehscheid P, Schwindt P, Adami B, Schroeder M, Klein O, Baldus M, Galle PR, Heike M. Safety and efficacy of outpatient treatment with CPT-11 plus bolus folinic acid/5-fluorouracil as first-line chemotherapy for metastatic colorectal cancer. Anticancer Drugs 2003; 14: 79-85
-
(2003)
Anticancer Drugs
, vol.14
, pp. 79-85
-
-
Moehler, M.1
Hoffmann, T.2
Zanke, C.3
Hohl, H.4
Burg, H.5
Ehscheid, P.6
Schwindt, P.7
Adami, B.8
Schroeder, M.9
Klein, O.10
Baldus, M.11
Galle, P.R.12
Heike, M.13
-
16
-
-
13144304343
-
Irinotecan plus folinic acid/continuous 5-fluorouracil as simplified bimonthly FOLFIRI regimen for first-line therapy of metastatic colorectal cancer
-
Teufel A, Steinmann S, Siebler J, Zanke C, Hohl H, Adami B, Schroeder M, Klein O, Hohler T, Galle PR, Heike M, Moehler M. Irinotecan plus folinic acid/continuous 5-fluorouracil as simplified bimonthly FOLFIRI regimen for first-line therapy of metastatic colorectal cancer. BMC Cancer 2004; 4: 38
-
(2004)
BMC Cancer
, vol.4
, pp. 38
-
-
Teufel, A.1
Steinmann, S.2
Siebler, J.3
Zanke, C.4
Hohl, H.5
Adami, B.6
Schroeder, M.7
Klein, O.8
Hohler, T.9
Galle, P.R.10
Heike, M.11
Moehler, M.12
-
17
-
-
0042676659
-
Dose escalation and pharmacokinetic study of capecitabine (Xeloda) and irinotecan (CPT-11) in gastrointestinal tumors: Preliminary results
-
Delord JP, Pierga JY, Dieras V, Bertheault-Cvitkovic F, Turpin FL, Lokiec F, Canal P, Chatelut E, Guimbaud R, Cornen X. Dose escalation and pharmacokinetic study of capecitabine (Xeloda) and irinotecan (CPT-11) in gastrointestinal tumors: preliminary results. Proc Am Soc Clin Oncol 2002, 21: A397
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
-
-
Delord, J.P.1
Pierga, J.Y.2
Dieras, V.3
Bertheault-Cvitkovic, F.4
Turpin, F.L.5
Lokiec, F.6
Canal, P.7
Chatelut, E.8
Guimbaud, R.9
Cornen, X.10
-
18
-
-
0012465969
-
A phase I/II study of CPT-11 in combination with capecitabine as first line chemotherapy for metastatic colorectal cancer (MCRC)
-
Kerr DJ, Ten Bokkel Huinink WW, Ferry DR, Rea DW, Boussard BM, Oulid-Aissa D, Frings S, Nortier JW. A phase I/II study of CPT-11 in combination with capecitabine as first line chemotherapy for metastatic colorectal cancer (MCRC). Proc Am Soc Clin Oncol 2002, 21: A643
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
-
-
Kerr, D.J.1
Ten Bokkel Huinink, W.W.2
Ferry, D.R.3
Rea, D.W.4
Boussard, B.M.5
Oulid-Aissa, D.6
Frings, S.7
Nortier, J.W.8
-
19
-
-
31544437749
-
A randomised cross-over trial comparing patient preference for oral capecitabine and 5-fluorouracil/leucovorin regimens in patients with advanced colorectal cancer
-
Twelves C, Gollins S, Grieve R, Samuel L. A randomised cross-over trial comparing patient preference for oral capecitabine and 5-fluorouracil/leucovorin regimens in patients with advanced colorectal cancer. Ann Oncol 2006; 17: 239-245
-
(2006)
Ann Oncol
, vol.17
, pp. 239-245
-
-
Twelves, C.1
Gollins, S.2
Grieve, R.3
Samuel, L.4
-
20
-
-
0141613762
-
Capecitabine and irinotecan as first-line chemotherapy in patients with metastatic colorectal cancer: Results of an extended phase I study
-
Tewes M, Schleucher N, Achterrath W, Wilke HJ, Frings S, Seeber S, Harstrick A, Rustum YM, Vanhoefer U. Capecitabine and irinotecan as first-line chemotherapy in patients with metastatic colorectal cancer: results of an extended phase I study. Ann Oncol 2003; 14: 1442-1448
-
(2003)
Ann Oncol
, vol.14
, pp. 1442-1448
-
-
Tewes, M.1
Schleucher, N.2
Achterrath, W.3
Wilke, H.J.4
Frings, S.5
Seeber, S.6
Harstrick, A.7
Rustum, Y.M.8
Vanhoefer, U.9
-
21
-
-
9144255466
-
Randomized multicenter Phase II trial of two different schedules of irinotecan combined with capecitabine as first-line treatment in metastatic colorectal carcinoma
-
Bajetta E, Di Bartolomeo M, Mariani L, Cassata A, Artale S, Frustaci S, Pinotti G, Bonetti A, Carreca I, Biasco G, Bonaglia L, Marini G, Iannelli A, Cortinovis D, Ferrario E, Beretta E, Lambiase A, Buzzoni R. Randomized multicenter Phase II trial of two different schedules of irinotecan combined with capecitabine as first-line treatment in metastatic colorectal carcinoma. Cancer 2004; 100: 279-287
-
(2004)
Cancer
, vol.100
, pp. 279-287
-
-
Bajetta, E.1
Di Bartolomeo, M.2
Mariani, L.3
Cassata, A.4
Artale, S.5
Frustaci, S.6
Pinotti, G.7
Bonetti, A.8
Carreca, I.9
Biasco, G.10
Bonaglia, L.11
Marini, G.12
Iannelli, A.13
Cortinovis, D.14
Ferrario, E.15
Beretta, E.16
Lambiase, A.17
Buzzoni, R.18
-
22
-
-
0042714530
-
Randomized phase II trial of capecitabine plus irinotecan (CapIri) vs capecitabine plus oxaliplatin (CapOx) as first-line therapy of advanced colorectal cancer (ACRC)
-
Grothey A, Jordan K, Kellner O, Constantin C, Dittrich G, Kroening H, Mantovani L, Schlichting C, Forstbauer H, Schmoll HJ. Randomized phase II trial of capecitabine plus irinotecan (CapIri) vs capecitabine plus oxaliplatin (CapOx) as first-line therapy of advanced colorectal cancer (ACRC). Proc Am Soc Clin Oncol 2003, 22: A1022
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
-
-
Grothey, A.1
Jordan, K.2
Kellner, O.3
Constantin, C.4
Dittrich, G.5
Kroening, H.6
Mantovani, L.7
Schlichting, C.8
Forstbauer, H.9
Schmoll, H.J.10
-
23
-
-
21844472538
-
Results of a phase II open-label study of capecitabine in combination with irinotecan as first-line treatment for metastatic colorectal cancer
-
Cartwright T, Lopez T, Vukelja SJ, Encarnacion C, Boehm KA, Asmar L. Results of a phase II open-label study of capecitabine in combination with irinotecan as first-line treatment for metastatic colorectal cancer. Clin Colorectal Cancer 2005; 5: 50-56
-
(2005)
Clin Colorectal Cancer
, vol.5
, pp. 50-56
-
-
Cartwright, T.1
Lopez, T.2
Vukelja, S.J.3
Encarnacion, C.4
Boehm, K.A.5
Asmar, L.6
-
24
-
-
34447277453
-
Sequential versus combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): A phase III randomised controlled trial
-
Koopman M, Antonini NF, Douma J, Wals J, Honkoop AH, Erdkamp FL, de Jong RS, Rodenburg CJ, Vreugdenhil G, Loosveld OJ, van Bochove A, Sinnige HA, Creemers GJ, Tesselaar ME, Slee PH, Werter MJ, Mol L, Dalesio O, Punt CJ. Sequential versus combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): a phase III randomised controlled trial. Lancet 2007; 370: 135-142
-
(2007)
Lancet
, vol.370
, pp. 135-142
-
-
Koopman, M.1
Antonini, N.F.2
Douma, J.3
Wals, J.4
Honkoop, A.H.5
Erdkamp, F.L.6
de Jong, R.S.7
Rodenburg, C.J.8
Vreugdenhil, G.9
Loosveld, O.J.10
van Bochove, A.11
Sinnige, H.A.12
Creemers, G.J.13
Tesselaar, M.E.14
Slee, P.H.15
Werter, M.J.16
Mol, L.17
Dalesio, O.18
Punt, C.J.19
-
25
-
-
34247849335
-
Target practice: Lessons from phase III trials with bevacizumab and vatalanib in the treatment of advanced colorectal cancer
-
Los M, Roodhart JM, Voest EE. Target practice: lessons from phase III trials with bevacizumab and vatalanib in the treatment of advanced colorectal cancer. Oncologist 2007; 12: 443-450
-
(2007)
Oncologist
, vol.12
, pp. 443-450
-
-
Los, M.1
Roodhart, J.M.2
Voest, E.E.3
-
26
-
-
18444408417
-
New combinations in metastatic colorectal cancer: What are our expectations?
-
Hurwitz H. New combinations in metastatic colorectal cancer: what are our expectations? Oncologist 2005; 10: 320-322
-
(2005)
Oncologist
, vol.10
, pp. 320-322
-
-
Hurwitz, H.1
-
27
-
-
33749016960
-
Safety and efficacy of oxaliplatin/fluoropyrimidine regimens with or without bevacizumab as first-line treatment of metastatic colorectal cancer (mCRC): Final analysis of the TREE-Study
-
Hochster HS, Hart LL, Ramanathan RK, Hainsworth JD, Hedrick EE, Childs BH. Safety and efficacy of oxaliplatin/fluoropyrimidine regimens with or without bevacizumab as first-line treatment of metastatic colorectal cancer (mCRC): Final analysis of the TREE-Study. J Clin Oncol 2006, 24: A3510
-
(2006)
J Clin Oncol
, vol.24
-
-
Hochster, H.S.1
Hart, L.L.2
Ramanathan, R.K.3
Hainsworth, J.D.4
Hedrick, E.E.5
Childs, B.H.6
-
28
-
-
59249098751
-
-
Fernando N, Yu D, Morse M, Blobe G, Odogwu L, Crews J, Polito A, Honeycutt W, Franklin A, Hurwitz H. A phase II study of oxaliplatin, capecitabine and bevacizumab in the treatment of metastatic colorectal cancer. J Clin Oncol 2005, 23: A3556; updated information presented at meeting
-
Fernando N, Yu D, Morse M, Blobe G, Odogwu L, Crews J, Polito A, Honeycutt W, Franklin A, Hurwitz H. A phase II study of oxaliplatin, capecitabine and bevacizumab in the treatment of metastatic colorectal cancer. J Clin Oncol 2005, 23: A3556; updated information presented at meeting
-
-
-
-
29
-
-
33748752619
-
-
Giantonio BJ, Levy DE, O'dwyer PJ, Meropol NJ, Catalano PJ, Benson AB 3rd. A phase II study of high-dose bevacizumab in combination with irinotecan, 5-fluorouracil, leucovorin, as initial therapy for advanced colorectal cancer: results from the Eastern Cooperative Oncology Group study E2200. Ann Oncol 2006; 17: 1399-1403
-
Giantonio BJ, Levy DE, O'dwyer PJ, Meropol NJ, Catalano PJ, Benson AB 3rd. A phase II study of high-dose bevacizumab in combination with irinotecan, 5-fluorouracil, leucovorin, as initial therapy for advanced colorectal cancer: results from the Eastern Cooperative Oncology Group study E2200. Ann Oncol 2006; 17: 1399-1403
-
-
-
-
30
-
-
34548625212
-
Survival of patients (pts) with mCRC treated with bevacizumab in combination with chemotherapy: Results from the BRiTE registry
-
updated information presented at ASCO GI
-
Kozloff M, Hainsworth J, Badarinath S, Cohn A, Flynn PJ, Dong W, Suzuki S, Sarkar S, Sugrue MM, Grothey A. Survival of patients (pts) with mCRC treated with bevacizumab in combination with chemotherapy: Results from the BRiTE registry. ASCO Gastrointestinal Cancer Symposium, 2007: A375; updated information presented at ASCO GI
-
(2007)
ASCO Gastrointestinal Cancer Symposium
-
-
Kozloff, M.1
Hainsworth, J.2
Badarinath, S.3
Cohn, A.4
Flynn, P.J.5
Dong, W.6
Suzuki, S.7
Sarkar, S.8
Sugrue, M.M.9
Grothey, A.10
-
31
-
-
33750737920
-
Efficacy and safety of bevacizumab in combination with irinotecan and infusional 5-FU as first-line treatment for patients with metastatic colorectal cancer
-
Sobrero AF, Ackland S, Carrion RP, Chiara S, Clarke S, Giron CG, Langer B, Zurlo A, Young S. Efficacy and safety of bevacizumab in combination with irinotecan and infusional 5-FU as first-line treatment for patients with metastatic colorectal cancer. J Clin Oncol 2006, 24: A3544
-
(2006)
J Clin Oncol
, vol.24
-
-
Sobrero, A.F.1
Ackland, S.2
Carrion, R.P.3
Chiara, S.4
Clarke, S.5
Giron, C.G.6
Langer, B.7
Zurlo, A.8
Young, S.9
-
32
-
-
42949131781
-
Preliminary safety of bevacizumab with first-line FOLFOX, CAPOX, FOLFIRI and capecitabine for mCRC - First BEAT trial
-
Van Cutsem E, Michael M, Berry S, Bartolomeo M, Kretzschmar A, Rivera F, Lutiger B, Mazier M, Cunningham D. Preliminary safety of bevacizumab with first-line FOLFOX, CAPOX, FOLFIRI and capecitabine for mCRC - First BEAT trial. ASCO Gastrointestinal Cancer Symposium, 2006: A250
-
(2006)
ASCO Gastrointestinal Cancer Symposium
-
-
Van Cutsem, E.1
Michael, M.2
Berry, S.3
Bartolomeo, M.4
Kretzschmar, A.5
Rivera, F.6
Lutiger, B.7
Mazier, M.8
Cunningham, D.9
-
33
-
-
42949131781
-
Preliminary safety and efficacy of bevacizumab with first-line FOLFOX, XELOX, FOLFIRI, and capecitabine for mCRC: First BEAT trial
-
Van Cutsem E, Michael M, Berry S, Dibartolomeo M, Rivera F, Kretzschmar A, Mazier M, Lutiger B, Cunningham D. Preliminary safety and efficacy of bevacizumab with first-line FOLFOX, XELOX, FOLFIRI, and capecitabine for mCRC: First BEAT trial. ASCO Gastrointestinal Cancer Symposium, 2007: A346
-
(2007)
ASCO Gastrointestinal Cancer Symposium
-
-
Van Cutsem, E.1
Michael, M.2
Berry, S.3
Dibartolomeo, M.4
Rivera, F.5
Kretzschmar, A.6
Mazier, M.7
Lutiger, B.8
Cunningham, D.9
-
34
-
-
0034594628
-
New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
-
Therasse P, Arbuck SG, Eisenhauer EA, Wanders J, Kaplan RS, Rubinstein L, Verweij J, Van Glabbeke M, van Oosterom AT, Christian MC, Gwyther SG. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 2000; 92: 205-216
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 205-216
-
-
Therasse, P.1
Arbuck, S.G.2
Eisenhauer, E.A.3
Wanders, J.4
Kaplan, R.S.5
Rubinstein, L.6
Verweij, J.7
Van Glabbeke, M.8
van Oosterom, A.T.9
Christian, M.C.10
Gwyther, S.G.11
-
35
-
-
54549124110
-
Phase IV study of first-line bevacizumab plus irinotecan and infusional 5-FU/LV in patients with metastatic colorectal cancer: AVIRI
-
Sobrero AF, Young S, Balcewicz M, Chiarra S, Perez Carrion R, Mainwaring P, Gapski J, Clarke S, Langer B, Ackland S. Phase IV study of first-line bevacizumab plus irinotecan and infusional 5-FU/LV in patients with metastatic colorectal cancer: AVIRI. J Clin Oncol 2007; 25: A4068
-
(2007)
J Clin Oncol
, vol.25
-
-
Sobrero, A.F.1
Young, S.2
Balcewicz, M.3
Chiarra, S.4
Perez Carrion, R.5
Mainwaring, P.6
Gapski, J.7
Clarke, S.8
Langer, B.9
Ackland, S.10
-
36
-
-
36048960109
-
Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: Results from the BICC-C Study
-
Fuchs CS, Marshall J, Mitchell E, Wierzbicki R, Ganju V, Jeffery M, Schulz J, Richards D, Soufi-Mahjoubi R, Wang B, Barrueco J. Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: results from the BICC-C Study. J Clin Oncol 2007; 25: 4779-4786
-
(2007)
J Clin Oncol
, vol.25
, pp. 4779-4786
-
-
Fuchs, C.S.1
Marshall, J.2
Mitchell, E.3
Wierzbicki, R.4
Ganju, V.5
Jeffery, M.6
Schulz, J.7
Richards, D.8
Soufi-Mahjoubi, R.9
Wang, B.10
Barrueco, J.11
-
37
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W, Cartwright T, Hainsworth J, Heim W, Berlin J, Baron A, Griffing S, Holmgren E, Ferrara N, Fyfe G, Rogers B, Ross R, Kabbinavar F. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350: 2335-2342
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
Berlin, J.7
Baron, A.8
Griffing, S.9
Holmgren, E.10
Ferrara, N.11
Fyfe, G.12
Rogers, B.13
Ross, R.14
Kabbinavar, F.15
-
38
-
-
20044384354
-
A randomized phase II trial of capecitabine and two different schedules of irinotecan in first-line treatment of metastatic colorectal cancer: Efficacy, quality-of-life and toxicity
-
Borner MM, Bernhard J, Dietrich D, Popescu R, Wernli M, Saletti P, Rauch D, Herrmann R, Koeberle D, Honegger H, Brauchli P, Lanz D, Roth AD. A randomized phase II trial of capecitabine and two different schedules of irinotecan in first-line treatment of metastatic colorectal cancer: efficacy, quality-of-life and toxicity. Ann Oncol 2005; 16: 282-288
-
(2005)
Ann Oncol
, vol.16
, pp. 282-288
-
-
Borner, M.M.1
Bernhard, J.2
Dietrich, D.3
Popescu, R.4
Wernli, M.5
Saletti, P.6
Rauch, D.7
Herrmann, R.8
Koeberle, D.9
Honegger, H.10
Brauchli, P.11
Lanz, D.12
Roth, A.D.13
-
39
-
-
56849092722
-
Activity of the combination of bevacizumab (Bev) with capecitabine/ irinotecan (CapIri/Bev) or capecitabine/oxaliplatin (CapOx/Bev) in advanced colorectal cancer (ACRC): A randomized phase II study of the AIO Colorectal Study Group (AIO trial 0604)
-
Reinacher-Schick AC, Kubicka S, Freier W, Arnold D, Dietrich G, Geissler M, Hegewisch-Becker S, Graeven U, Schmoll H, Schmiegel W: Activity of the combination of bevacizumab (Bev) with capecitabine/ irinotecan (CapIri/Bev) or capecitabine/oxaliplatin (CapOx/Bev) in advanced colorectal cancer (ACRC): A randomized phase II study of the AIO Colorectal Study Group (AIO trial 0604). J Clin Oncol 2008; 26: A4030
-
(2008)
J Clin Oncol
, vol.26
-
-
Reinacher-Schick, A.C.1
Kubicka, S.2
Freier, W.3
Arnold, D.4
Dietrich, G.5
Geissler, M.6
Hegewisch-Becker, S.7
Graeven, U.8
Schmoll, H.9
Schmiegel, W.10
-
40
-
-
59249093445
-
-
Schmiegel WH, Reinacher-Schick A, Freier W, Dietrich G, Arnold D, Kanzler S, Geissler M, Graeven U, Hegewisch-Becker S, Schmoll H. Comparable safety and response rate with bevacizumab in combination with capecitabine/oxaliplatin (CapOx/Bev) versus capecitabine/irinotecan (Caplri/Bev) in advanced CRC (mCRC): A randomized phase II study of the AIO GI tumor study group. J Clin Oncol 2007; 25: A4034; Updated information presented at meeting
-
Schmiegel WH, Reinacher-Schick A, Freier W, Dietrich G, Arnold D, Kanzler S, Geissler M, Graeven U, Hegewisch-Becker S, Schmoll H. Comparable safety and response rate with bevacizumab in combination with capecitabine/oxaliplatin (CapOx/Bev) versus capecitabine/irinotecan (Caplri/Bev) in advanced CRC (mCRC): A randomized phase II study of the AIO GI tumor study group. J Clin Oncol 2007; 25: A4034; Updated information presented at meeting
-
-
-
-
41
-
-
59249096724
-
-
de Greve J, Kohne CH, Hartmann J, Lang I, Vergauwe P, Becker K, Braumann D. Capecitabine plus irinotecan versus 5-FU/FA/irinotecan ± celecoxib in first line treatment of metastatic colorectal cancer (CRC). Long-term results of the prospective multicenter EORTC phase III study 40015. J Clin Oncol 2006; 24: A3577; virtual presentation www.asco.org
-
de Greve J, Kohne CH, Hartmann J, Lang I, Vergauwe P, Becker K, Braumann D. Capecitabine plus irinotecan versus 5-FU/FA/irinotecan ± celecoxib in first line treatment of metastatic colorectal cancer (CRC). Long-term results of the prospective multicenter EORTC phase III study 40015. J Clin Oncol 2006; 24: A3577; virtual presentation www.asco.org
-
-
-
-
42
-
-
28244499031
-
Capecitabine plus irinotecan versus 5-FU/FA/irinotecan +/- celecoxib in first line treatment of metastatic colorectal cancer. Safety results of the prospective multicenter EORTC phase III study 40015
-
Kohne CH, de Greve J, Bokemeyer C, Lang I, Vergauwe P, Braumann D, Debois M. Capecitabine plus irinotecan versus 5-FU/FA/irinotecan +/- celecoxib in first line treatment of metastatic colorectal cancer. Safety results of the prospective multicenter EORTC phase III study 40015. J Clin Oncol 2005; 23: A3525
-
(2005)
J Clin Oncol
, vol.23
-
-
Kohne, C.H.1
de Greve, J.2
Bokemeyer, C.3
Lang, I.4
Vergauwe, P.5
Braumann, D.6
Debois, M.7
-
43
-
-
0037208589
-
Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer
-
Kabbinavar F, Hurwitz HI, Fehrenbacher L, Meropol NJ, Novotny WF, Lieberman G, Griffing S, Bergsland E. Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer. J Clin Oncol 2003; 21: 60-65
-
(2003)
J Clin Oncol
, vol.21
, pp. 60-65
-
-
Kabbinavar, F.1
Hurwitz, H.I.2
Fehrenbacher, L.3
Meropol, N.J.4
Novotny, W.F.5
Lieberman, G.6
Griffing, S.7
Bergsland, E.8
-
44
-
-
28344438302
-
Arterial thromboembolic events (ATEs) in a pooled analysis of 5 randomized, controlled trials (RCTs) of bevacizumab (BV) with chemotherapy
-
Skillings JR, Johnson D, Miller K, Kabbinavar F, Bergsland E, Holmgren E, Holden S, Hurwitz H, Scappaticci F. Arterial thromboembolic events (ATEs) in a pooled analysis of 5 randomized, controlled trials (RCTs) of bevacizumab (BV) with chemotherapy. J Clin Oncol 2005, 23: A3019
-
(2005)
J Clin Oncol
, vol.23
-
-
Skillings, J.R.1
Johnson, D.2
Miller, K.3
Kabbinavar, F.4
Bergsland, E.5
Holmgren, E.6
Holden, S.7
Hurwitz, H.8
Scappaticci, F.9
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