Thromboembolic events during chemotherapy for germ cell cancer: A cohort study and review of the literature

Journal of Clinical Oncology

Volumn 18, Issue 10, 2000, Pages 2169-2178

  Weijl, Nir I ^a   Rutten, Marc F J ^a   Zwinderman, Aeilko H ^a   Jan Keizer, H ^a   Nooy, Marianne A ^a   Rosendaal, Frits R ^a   Cleton, Frans J ^a   Osanto, Susanne ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; CISPLATIN; DEXAMETHASONE; ETOPOSIDE; VINBLASTINE;

ADOLESCENT; ADULT; BRAIN ISCHEMIA; CANCER CHEMOTHERAPY; CANCER PATIENT; CEREBROVASCULAR ACCIDENT; GERM CELL TUMOR; HUMAN; LIVER METASTASIS; LUNG EMBOLISM; PRIORITY JOURNAL; REVIEW; RISK FACTOR; THROMBOEMBOLISM;

EID: 0034111118     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2000.18.10.2169     Document Type: Review

References (56)

1. Margileth DA, Smith FE, Lane M: Sudden arterial occlusion associated with mithramycin therapy. Cancer 31:708-712, 1973
2. Berman IJ, Mann MP: Seizures and transient cortical blindness associated with cis-platinum (II) diamminedichloride (PDD) therapy in a thirty-year-old man. Cancer 45:764-766, 1980
3. Bodensteiner DC: Fatal coronary artery fibrosis after treatment with bleomycin, vinblastine, and cis-platinum. South Med J 74:898-899, 1981
4. Cohen RJ, Cuneo RA, Cruciger MP, et al: Transient left homonymous hemianopsia and encephalopathy following treatment of testicular carcinoma with cisplatinum, vinblastine, and bleomycin. J Clin Oncol 1:392-393, 1983
5. Lederman GS, Garnick MB: Pulmonary emboli as a complication of germ cell cancer treatment. J Urol 137:1236-1237, 1987
6. Samuels BL, Vogelzang NJ, Kennedy BJ: Severe vascular toxicity associated with vinblastine, bleomycin, and cisplatin chemotherapy. Cancer Chemother Pharmacol 19:253-256, 1987
7. Hall MR, Richards MA, Harper PG: Thromboembolic events during combination chemotherapy for germ cell malignancy. Lancet 2:1259, 1988 (letter)
8. Zeymer U, Neuhaus KL: Infarct-typical changes in the electrocardiogram following chemotherapy with vinblastine. Dtsch Med Wochenschr 114:589-592, 1989 (in German)
9. Berliner S, Rahima M, Sidi Y, et al: Acute coronary events following cisplatin-based chemotherapy. Cancer Invest 8:583-586, 1990
10. Garstin IWH, Cooper GG, Hood JM: Arterial thrombosis after treatment with bleomycin and cisplatin. BMJ 300:1018, 1990 (letter)
11. Borek G, Gebel F, Jenzer HR: Acute myocardial infarct following chemotherapy for testicular carcinoma: On the coronary toxicity of cytostatic agents. Schweiz Med Wochenschr 121:385-389, 1991 (in German)
12. Gerl A, Clemm C, Wilmanns W: Acute cerebrovascular event after cisplatin-based chemotherapy for testicular cancer. Lancet 338: 385-386, 1991 (letter)
13. Schwarzer S, Eber B, Greinix H, et al: Non-Q-wave myocardial infarction associated with bleomycin and etoposide chemotherapy. Eur Heart J 12:748-750, 1991
14. Gerl A, Clemm C, Schleuning M, et al: Fatal cerebrovascular accident associated with chemotherapy for testicular cancer. Eur J Cancer 29A:1220-1221, 1993 (letter)
15. Içli F, Karaoǧuz H, Dinçol D, et al: Severe vascular toxicity associated with cisplatin-based chemotherapy. Cancer 72:587-593, 1993
16. Airey CL, Dodwell DJ, Joffe JK, et al: Etoposide-related myocardial infarction. Clin Oncol (R Coll Radiol) 7:135, 1995
17. Schmidt J, Zenut M, De Marquilly F, et al: Arterial thrombosis in a patient after chemotherapy (BEP protocol) for extra-gonadal dysgerminoma. Therapie 50:476-478, 1995 (in French)
18. Lepidini G, Biancari F, Dándrea V: Severe thrombosis after chemotherapy for metastatic choriocarcinoma of the testis maintaining complete remission for a long period. Scand J Urol Nephrol 31:221-222, 1996
19. Shlebak AA, Smith DB: Incidence of objectively diagnosed thromboembolic disease in cancer patients undergoing cytotoxic chemotherapy and/or hormonal therapy. Cancer Chemother Pharmacol 39:462-466, 1997
20. Bosl GJ, Gluckman R, Geller NL, et al: VAB-6: An effective chemotherapy regimen for patients with germ-cell tumors. J Clin Oncol 4:1493-1499, 1986
21. Doll DC, List AF, Greco FA, et al: Acute vascular ischemic events after cisplatin-based combination chemotherapy for germ-cell tumors of the testis. Ann Intern Med 105:48-51, 1986
22. Cantwell BMJ, Mannix KA, Roberts JT, et al: Thromboembolic events during combination chemotherapy for germ cell malignancy. Lancet 2:1086-1087, 1988 (letter)
23. Stefenelli T, Kuzmits R, Ulrich W, et al: Acute vascular toxicity after combination chemotherapy with cisplatin, vinblastine, and bleomycin for testicular cancer. Eur Heart J 9:552-556, 1988
24. Clemm C, Hartenstein R, Willich N, et al: Combination chemotherapy with vinblastine, ifosfamide and cisplatin in bulky seminoma. Acta Oncol 28:231-235, 1989
25. Nichols CR, Williams SD, Loehrer PJ, et al: Randomized study of cisplatin dose intensity in poor-risk germ cell tumors: a Southeastern Cancer Study Group and Southwest Oncology Group protocol. J Clin Oncol 9:1163-1172, 1991
26. Coates AS, Childs A, Cox K, et al: Severe vascular adverse effects with thrombocytopenia and renal failure following emetogenic chemotherapy and ondansetron. Ann Oncol 3:719-722, 1992
27. Ellis PA, Fitzharris BM, George PM, et al: Fasting plasma lipid measurements following cisplatin chemotherapy in patients with germ cell tumors. J Clin Oncol 10:1609-1614, 1992
28. Hassan B, Tung K, Weeks R, et al: The management of inferior vena cava obstruction complicating metastatic germ cell tumors. Cancer 85:912-918, 1999
29. Nichols CR, Roth BJ, Williams SD, et al: No evidence of acute cardiovascular complications of chemotherapy for testicular cancer: An analysis of the Testicular Cancer Intergroup study. J Clin Oncol 10:760-765, 1992
30. Rosendaal FR: Venous thrombosis: A multicausal disease. Lancet 353:1167-1173, 1999
31. Rickles FR, Edwards RL: Activation of blood coagulation in cancer: Trousseau's syndrome revisited. Blood 62:14-31, 1983
32. Durica SS: Venous thromboembolism in the cancer patient. Curr Opin Hematol 4:306-311, 1997
33. Gerl A: Vascular toxicity associated with chemotherapy for testicular cancer. Anticancer Drugs 5:607-614, 1994
34. Bertina RM, Koeleman RPC, Koster T, et al: Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 369:64-67, 1994
35. Poort SR, Rosendaal FR, Reitsma PH, et al: A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 88:3698-3703, 1996
36. Anderson FA, Wheeler HB, Goldberg RJ, et al: A population based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism: The Worcester DVT study. Arch Intern Med 151:933-938, 1991
37. Mostofi FK, Sobin LH: International Histological Classification of Tumors of Testes. Geneva, Switzerland, World Health Organization, publication no. 16, 1977
38. Dawson P, Hewitt P, Mackie IJ, et al: Contrast, coagulation, and fibrinolysis. Invest Radiol 21:248-252, 1988
39. Bredael JJ, Vugrin D, Whitmore WF: Autopsy findings in 154 patients with germ cell tumors of the testis. Cancer 50:548-551, 1982
40. Stockler M, Raghavan D: Neoplastic venous involvement and pulmonary embolism in patients with germ cell tumors. Cancer 68:2633-2636, 1991
41. Dvorak HF, Van DeWater L, Bitzer AM, et al: Procoagulant activity associated with plasma membrane vesicles shed by cultured tumor cells. Cancer Res 43:4334-4342, 1983
42. Honegger H, Anderson N, Hewitt LA, et al: Antithrombin III profiles in malignancy: Relationship to primary tumors and metastatic sites. Thromb Haemost 46:500-503, 1981
43. Nand S, Gross Fisher S, Salgia R, et al: Hemostatic abnormalities in untreated cancer: Incidence and correlation with thrombotic and hemorrhagic complications. J Clin Oncol 5:1998-2003, 1987
44. Patrassi GM, Dal Bo Zanon R, Boscaro M, et al: Further studies on the hypercoagulable state of patients with Cushing's syndrome. Thromb Haemost 54:518-520, 1985
45. Cosgriff SW: Thromboembolic complications associated with ACTH and cortisone therapy. JAMA 147:924-926, 1951
46. Eisenmenger WJ, Slater RJ, Bongiovanni AM: Hypercoagulability of the blood of patients with hepatic cirrhosis following administration of ACTH. Am J Med 13:27-34, 1952
47. Jouquan J, Mottier D, Cleuziou A, et al: Early cerebral vascular accidents in treated Horton's disease: Responsibility of the corticoid treatment? Ann Med Interne (Paris) 135:526-529, 1984 (in French)
48. Goldhirsch A, Joss R, Markwalder TM, et al: Acute cerebrovascular accident after treatment with cis-platinum and methylprednisolone. Oncology 40:344-345, 1983
49. Van Giezen JJ, Brakkee JGP, Dreteler GH, et al: Dexamethasone affects platelet aggregation and fibrinolytic activity in rats at different doses which is reflected by their effect on arterial thrombosis. Blood Coagul Fibrinolysis 5:249-255, 1994
50. Öztürk G. Özsoylu S, Gürsel T: Effects of methylprednisolone on FVIII:C and vWF levels. Br J Haematol 53:119-120, 1994 (letter)
51. Gerrits WBJ, Prakke EM, van der Meer J, et al: Corticosteroids and experimental intravascular coagulation. Scand J Haematol 13:5-10, 1974
52. Kwaan HC, McFadzean AJS, Glasg MB: The inhibition of clot lysis by corticotrophin. Lancet 270:136-137, 1956
53. Levine MN, Gent M, Hirsh J, et al: The thrombogenic effect of anticancer drug therapy in women with stage II breast cancer. N Engl J Med 318:404-407, 1988
54. Wall JG, Weiss RB, Norton L, et al: Arterial thrombosis associated with adjuvant chemotherapy for breast carcinoma: A Cancer and Leukemia Group B study. Am J Med 87:501-504, 1989
55. Cantwell BMJ, Carmichael J, Ghani SE, et al: Thromboses and thromboemboli in patients with lymphoma during cytotoxic chemotherapy. BMJ 297:179-180, 1988
56. Weitz JI: Low-molecular-weight heparins. N Engl J Med 337: 688-698, 1997