In silico prediction of binding of promiscuous peptides to multiple MHC class-II molecules identifies the Th1 cell epitopes from secreted and transmembrane proteins of Schistosoma japonicum in BALB/c mice

Microbes and Infection

Volumn 13, Issue 7, 2011, Pages 709-719

  Zhao, Ben Peng ^a,b   Chen, Lei ^a,b   Zhang, Yan Li ^a   Yang, Jian Mei ^a   Jia, Kan ^a,b   Sui, Chuan Yu ^a,b   Yuan, Chun Xiu ^a   Lin, Jiao Jiao ^a   Feng, Xin Gang ^a  

^a AGRO ENVIRONMENTAL PROTECTION INSTITUTE   (China)

^b SHANGHAI NORMAL UNIVERSITY   (China)

Author keywords

Immunogenicity; In silico prediction; Promiscuous Th epitope; Schistosoma japonicum; Secreted and transmembrane proteins

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; EPITOPE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MEMBRANE PROTEIN; TRANSCRIPTOME;

ALGORITHM; ARTICLE; BIOINFORMATICS; COMPUTER MODEL; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; FLOW CYTOMETRY; IMMUNIZATION; IN VITRO STUDY; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROTEIN BINDING; SCHISTOSOMA JAPONICUM; TH1 CELL;

ALGORITHMS; ANIMALS; ANTIGENS, HELMINTH; CELL PROLIFERATION; COMPUTATIONAL BIOLOGY; CYTOKINES; EPITOPES, T-LYMPHOCYTE; FEMALE; GENE EXPRESSION PROFILING; GENES, MHC CLASS II; HUMANS; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; RECOMBINANT PROTEINS; SCHISTOSOMA JAPONICUM; SCHISTOSOMIASIS JAPONICA; SEQUENCE ANALYSIS, PROTEIN; TH1 CELLS;

MURINAE; MUS; SCHISTOSOMA; SCHISTOSOMA JAPONICUM;

EID: 79957754767     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2011.03.005     Document Type: Article

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