메뉴 건너뛰기




Volumn 9, Issue 3, 2009, Pages 344-350

An in silico immunological approach for prediction of CD8+ T cell epitopes of Leishmania major proteins in susceptible BALB/c and resistant C57BL/6 murine models of infection

Author keywords

BALB c; C57BL 6; CD8 T cells; Epitopes; In silico; Leishmania major; Prediction

Indexed keywords

ANTILEISHMANIAL AGENT; CD4 ANTIGEN; CD8 ANTIGEN; EPITOPE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROTOZOAL PROTEIN;

EID: 64749100632     PISSN: 15671348     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.meegid.2008.02.011     Document Type: Article
Times cited : (18)

References (44)
  • 1
    • 0346742532 scopus 로고    scopus 로고
    • A strategy for the identification of T-cell epitopes on Leishmania cysteine proteinases
    • Alves C.R., Pontes de Carvalho L.C., Souza A.L., and De Simone S.G. A strategy for the identification of T-cell epitopes on Leishmania cysteine proteinases. Cytobios 104 (2001) 33-41
    • (2001) Cytobios , vol.104 , pp. 33-41
    • Alves, C.R.1    Pontes de Carvalho, L.C.2    Souza, A.L.3    De Simone, S.G.4
  • 3
    • 33947601157 scopus 로고    scopus 로고
    • The cross-priming pathway: a portrait of an intricate immune system
    • Basta S., and Alatery A. The cross-priming pathway: a portrait of an intricate immune system. Scand. J. Immunol. 65 (2007) 311-319
    • (2007) Scand. J. Immunol. , vol.65 , pp. 311-319
    • Basta, S.1    Alatery, A.2
  • 4
    • 0037090268 scopus 로고    scopus 로고
    • CD8+ T cells are required for primary immunity in C57BL/6 mice following low-dose, intradermal challenge with Leishmania major
    • Belkaid Y., Von Stebut E., Mendez S., Lira R., Caler E., Bertholet S., Udey M.C., and Sacks D. CD8+ T cells are required for primary immunity in C57BL/6 mice following low-dose, intradermal challenge with Leishmania major. J. Immunol. 168 (2002) 3992-4000
    • (2002) J. Immunol. , vol.168 , pp. 3992-4000
    • Belkaid, Y.1    Von Stebut, E.2    Mendez, S.3    Lira, R.4    Caler, E.5    Bertholet, S.6    Udey, M.C.7    Sacks, D.8
  • 7
    • 0017126775 scopus 로고
    • Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay
    • Bevan M.J. Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay. J. Exp. Med. 143 (1976) 1283-1288
    • (1976) J. Exp. Med. , vol.143 , pp. 1283-1288
    • Bevan, M.J.1
  • 8
    • 0035055496 scopus 로고    scopus 로고
    • Flow cytometric determination of cellular sources and frequencies of key cytokine-producing lymphocytes directed against recombinant LACK and soluble Leishmania antigen in human cutaneous leishmaniasis
    • Bottrel R.L., Dutra W.O., Martins F.A., Gontijo B., Carvalho E., Barral-Netto M., Barral A., Almeida R.P., Mayrink W., Locksley R., and Gollob K.J. Flow cytometric determination of cellular sources and frequencies of key cytokine-producing lymphocytes directed against recombinant LACK and soluble Leishmania antigen in human cutaneous leishmaniasis. Infect. Immun. 69 (2001) 3232-3239
    • (2001) Infect. Immun. , vol.69 , pp. 3232-3239
    • Bottrel, R.L.1    Dutra, W.O.2    Martins, F.A.3    Gontijo, B.4    Carvalho, E.5    Barral-Netto, M.6    Barral, A.7    Almeida, R.P.8    Mayrink, W.9    Locksley, R.10    Gollob, K.J.11
  • 9
    • 0031278398 scopus 로고    scopus 로고
    • Parasite-driven in vitro human lymphocyte cytotoxicity against autologous infected macrophages from mucosal leishmaniasis
    • Brodskyn C.I., Barral A., Boaventura V., Carvalho E., and Barral-Netto M. Parasite-driven in vitro human lymphocyte cytotoxicity against autologous infected macrophages from mucosal leishmaniasis. J. Immunol. 159 (1997) 4467-4473
    • (1997) J. Immunol. , vol.159 , pp. 4467-4473
    • Brodskyn, C.I.1    Barral, A.2    Boaventura, V.3    Carvalho, E.4    Barral-Netto, M.5
  • 10
    • 0028148460 scopus 로고
    • Leishmania major infection in mice primes for specific major histocompatibility complex class I-restricted cytotoxic T cell responses
    • Da Conceicao-Silva F., Perlaza B., Louis J.A., and Romero P. Leishmania major infection in mice primes for specific major histocompatibility complex class I-restricted cytotoxic T cell responses. Eur. J. Immunol. 24 (1994) 2813-2817
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2813-2817
    • Da Conceicao-Silva, F.1    Perlaza, B.2    Louis, J.A.3    Romero, P.4
  • 11
    • 0023616650 scopus 로고
    • Metacyclogenesis is a major determinant of Leishmania promastigote virulence and attenuation
    • da Silva R., and Sacks D.L. Metacyclogenesis is a major determinant of Leishmania promastigote virulence and attenuation. Infect. Immun. 55 (1987) 2802-2806
    • (1987) Infect. Immun. , vol.55 , pp. 2802-2806
    • da Silva, R.1    Sacks, D.L.2
  • 13
    • 0035425351 scopus 로고    scopus 로고
    • Antigen presentation to CD8+ T cells: cross-priming in infectious diseases
    • den Haan J.M., and Bevan M.J. Antigen presentation to CD8+ T cells: cross-priming in infectious diseases. Curr. Opin. Immunol. 13 (2001) 437-441
    • (2001) Curr. Opin. Immunol. , vol.13 , pp. 437-441
    • den Haan, J.M.1    Bevan, M.J.2
  • 14
    • 3042555141 scopus 로고    scopus 로고
    • Leishmaniasis: current situation and new perspectives
    • Desjeux P. Leishmaniasis: current situation and new perspectives. Comp. Immunol. Microbiol. Infect. Dis. 27 (2004) 305-318
    • (2004) Comp. Immunol. Microbiol. Infect. Dis. , vol.27 , pp. 305-318
    • Desjeux, P.1
  • 15
    • 33644928988 scopus 로고    scopus 로고
    • Leishmania donovani: identification of stimulatory soluble antigenic proteins using cured human and hamster lymphocytes for their prophylactic potential against visceral leishmaniasis
    • Garg R., Gupta S.K., Tripathi P., Hajela K., Sundar S., Naik S., and Dube A. Leishmania donovani: identification of stimulatory soluble antigenic proteins using cured human and hamster lymphocytes for their prophylactic potential against visceral leishmaniasis. Vaccine 24 (2006) 2900-2909
    • (2006) Vaccine , vol.24 , pp. 2900-2909
    • Garg, R.1    Gupta, S.K.2    Tripathi, P.3    Hajela, K.4    Sundar, S.5    Naik, S.6    Dube, A.7
  • 16
    • 1142269466 scopus 로고    scopus 로고
    • Immune recognition of a human renal cancer antigen through post-translational protein splicing
    • Hanada K., Yewdell J.W., and Yang J.C. Immune recognition of a human renal cancer antigen through post-translational protein splicing. Nature 427 (2004) 252-256
    • (2004) Nature , vol.427 , pp. 252-256
    • Hanada, K.1    Yewdell, J.W.2    Yang, J.C.3
  • 17
    • 0033061017 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte activation by cross-priming
    • Heath W.R., and Carbone F.R. Cytotoxic T lymphocyte activation by cross-priming. Curr. Opin. Immunol. 11 (1999) 314-318
    • (1999) Curr. Opin. Immunol. , vol.11 , pp. 314-318
    • Heath, W.R.1    Carbone, F.R.2
  • 18
    • 0020995834 scopus 로고
    • Leishmanial excreted factors and their possible biological role
    • Hernandez A.G. Leishmanial excreted factors and their possible biological role. Ciba Found. Symp. 99 (1983) 138-156
    • (1983) Ciba Found. Symp. , vol.99 , pp. 138-156
    • Hernandez, A.G.1
  • 19
    • 0024564206 scopus 로고
    • Elimination of CD4+ suppressor T cell from susceptible BALB/c mice release CD8+ T lymphocytes to mediate protective immunity against Leishmania
    • Hill J.O., Auwas M., and North R.J. Elimination of CD4+ suppressor T cell from susceptible BALB/c mice release CD8+ T lymphocytes to mediate protective immunity against Leishmania. J. Exp. Med. 169 (1989) 1819-1827
    • (1989) J. Exp. Med. , vol.169 , pp. 1819-1827
    • Hill, J.O.1    Auwas, M.2    North, R.J.3
  • 20
    • 0031825618 scopus 로고    scopus 로고
    • Effective and long-lasting immunity against the parasite Leishmania major in CD8-deficient mice
    • Huber M., Timms E., Mak T.W., Rollinghoff M., and Lohoff M. Effective and long-lasting immunity against the parasite Leishmania major in CD8-deficient mice. Infect. Immun. 66 (1998) 3968
    • (1998) Infect. Immun. , vol.66 , pp. 3968
    • Huber, M.1    Timms, E.2    Mak, T.W.3    Rollinghoff, M.4    Lohoff, M.5
  • 21
    • 0034918999 scopus 로고    scopus 로고
    • Heterogeneity of wild Leishmania major isolates in experimental murine pathogenicity and specific immune response
    • Kebaier C., Louzir H., Chenik M., Ben Salah A., and Dellagi K. Heterogeneity of wild Leishmania major isolates in experimental murine pathogenicity and specific immune response. Infect. Immun. 69 (2001) 4906-4915
    • (2001) Infect. Immun. , vol.69 , pp. 4906-4915
    • Kebaier, C.1    Louzir, H.2    Chenik, M.3    Ben Salah, A.4    Dellagi, K.5
  • 22
    • 15244360706 scopus 로고    scopus 로고
    • Protection against experimental visceral leishmaniasis infection in dogs immunized with purified excreted secreted antigens of Leishmania infantum promastigotes
    • Lemesre J.L., Holzmuller P., Cavaleyra M., Gonçalves R.B., Hottin G., and Papierok G. Protection against experimental visceral leishmaniasis infection in dogs immunized with purified excreted secreted antigens of Leishmania infantum promastigotes. Vaccine 23 (2005) 2825-2840
    • (2005) Vaccine , vol.23 , pp. 2825-2840
    • Lemesre, J.L.1    Holzmuller, P.2    Cavaleyra, M.3    Gonçalves, R.B.4    Hottin, G.5    Papierok, G.6
  • 23
    • 34247484942 scopus 로고    scopus 로고
    • Long-lasting protection against canine visceral leishmaniasis using the LiESAp-MDP vaccine in endemic areas of France: double-blind randomised efficacy field trial
    • Lemesre J.L., Holzmuller P., Gonçalves R.B., Bordoiseau G., Hugnet C., Cavaleyra M., and Papierok G. Long-lasting protection against canine visceral leishmaniasis using the LiESAp-MDP vaccine in endemic areas of France: double-blind randomised efficacy field trial. Vaccine 25 (2007) 4223-4234
    • (2007) Vaccine , vol.25 , pp. 4223-4234
    • Lemesre, J.L.1    Holzmuller, P.2    Gonçalves, R.B.3    Bordoiseau, G.4    Hugnet, C.5    Cavaleyra, M.6    Papierok, G.7
  • 24
    • 0023821578 scopus 로고
    • Introduction of soluble protein into the class I pathway of antigen processing and presentation
    • Moore M.W., Carbone F.R., and Bevan M.J. Introduction of soluble protein into the class I pathway of antigen processing and presentation. Cell 54 (1988) 777-785
    • (1988) Cell , vol.54 , pp. 777-785
    • Moore, M.W.1    Carbone, F.R.2    Bevan, M.J.3
  • 26
    • 0027254943 scopus 로고
    • Course of Leishmania infection in beta2-microglobulin-deficient mice
    • Overath P., and Harbecke D. Course of Leishmania infection in beta2-microglobulin-deficient mice. Immunol. Lett. 37 (1993) 13
    • (1993) Immunol. Lett. , vol.37 , pp. 13
    • Overath, P.1    Harbecke, D.2
  • 30
    • 0036727207 scopus 로고    scopus 로고
    • Prediction of MHC class I binding peptides using profile motifs
    • Reche P.A., Glutting J.-P., and Reinherz E.L. Prediction of MHC class I binding peptides using profile motifs. Hum. Immunol. 63 (2002) 701-709
    • (2002) Hum. Immunol. , vol.63 , pp. 701-709
    • Reche, P.A.1    Glutting, J.-P.2    Reinherz, E.L.3
  • 31
    • 0036017391 scopus 로고    scopus 로고
    • Protein degradation and the generation of MHC class I-presented peptides
    • Rock K.L., York I.A., Saric T., and Goldberg A.L. Protein degradation and the generation of MHC class I-presented peptides. Adv. Immunol. 80 (2002) 1-70
    • (2002) Adv. Immunol. , vol.80 , pp. 1-70
    • Rock, K.L.1    York, I.A.2    Saric, T.3    Goldberg, A.L.4
  • 32
    • 3242807547 scopus 로고    scopus 로고
    • Post-proteasomal antigen processing for major histocompatibility complex class I presentation
    • Rock K.L., York I.A., and Goldberg A.L. Post-proteasomal antigen processing for major histocompatibility complex class I presentation. Nat. Immunol. 5 (2004) 670-677
    • (2004) Nat. Immunol. , vol.5 , pp. 670-677
    • Rock, K.L.1    York, I.A.2    Goldberg, A.L.3
  • 33
    • 34248399629 scopus 로고    scopus 로고
    • Immunization with Leishmania infantum released proteins confers partial protection against parasite infection with a predominant Th1 specific immune response
    • Rosa R., Marques C., Rodrigues O.R., and Santos-Gomes G.M. Immunization with Leishmania infantum released proteins confers partial protection against parasite infection with a predominant Th1 specific immune response. Vaccine 6 (2007) 4525-4532
    • (2007) Vaccine , vol.6 , pp. 4525-4532
    • Rosa, R.1    Marques, C.2    Rodrigues, O.R.3    Santos-Gomes, G.M.4
  • 34
    • 0036831673 scopus 로고    scopus 로고
    • The immunology of susceptibility and resistance to Leishmania major in mice
    • Sacks D., and Noben-Trauth N. The immunology of susceptibility and resistance to Leishmania major in mice. Nat. Rev. Immunol. 2 (2002) 845-858
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 845-858
    • Sacks, D.1    Noben-Trauth, N.2
  • 35
    • 0028269769 scopus 로고
    • Leishmania major-specific CD8+ T cells are inducers and targets of nitric oxide produced by parasitized macrophages
    • Stefani M.M., Muller I., and Louis J.A. Leishmania major-specific CD8+ T cells are inducers and targets of nitric oxide produced by parasitized macrophages. Eur. J. Immunol. 24 (1994) 746-752
    • (1994) Eur. J. Immunol. , vol.24 , pp. 746-752
    • Stefani, M.M.1    Muller, I.2    Louis, J.A.3
  • 36
    • 0023200625 scopus 로고
    • Involvement of specific Lyt-2+ T cells in the immunological control of experimentally induced murine cutaneous leishmaniasis
    • Titus R.G., Milon G., Marchal G., Vassalli P., Cerottini J.C., and Louis J.A. Involvement of specific Lyt-2+ T cells in the immunological control of experimentally induced murine cutaneous leishmaniasis. Eur. J. Immunol. 17 (1987) 1429-1433
    • (1987) Eur. J. Immunol. , vol.17 , pp. 1429-1433
    • Titus, R.G.1    Milon, G.2    Marchal, G.3    Vassalli, P.4    Cerottini, J.C.5    Louis, J.A.6
  • 37
    • 4644242029 scopus 로고    scopus 로고
    • Immunization with Leishmania major exogenous antigens protects susceptible BALB/c mice against challenge infection with L. major
    • Tonui W.K., Mejia J.S., Hochberg L., Mbow M.L., Ryan J.R., Chan A.S., Martin S.K., and Titus R.G. Immunization with Leishmania major exogenous antigens protects susceptible BALB/c mice against challenge infection with L. major. Infect. Immun. 72 (2004) 5654-5661
    • (2004) Infect. Immun. , vol.72 , pp. 5654-5661
    • Tonui, W.K.1    Mejia, J.S.2    Hochberg, L.3    Mbow, M.L.4    Ryan, J.R.5    Chan, A.S.6    Martin, S.K.7    Titus, R.G.8
  • 38
    • 34247120998 scopus 로고    scopus 로고
    • Cross-protection against Leishmania donovani but not L. braziliensis caused by vaccination with L. major soluble promastigote exogenous antigens in BALB/c mice
    • Tonui W.K., and Titus R.G. Cross-protection against Leishmania donovani but not L. braziliensis caused by vaccination with L. major soluble promastigote exogenous antigens in BALB/c mice. Am. J. Trop. Med. Hyg. 76 (2007) 579-584
    • (2007) Am. J. Trop. Med. Hyg. , vol.76 , pp. 579-584
    • Tonui, W.K.1    Titus, R.G.2
  • 39
    • 0035893005 scopus 로고    scopus 로고
    • Immune elimination of Leishmania major in mice: implications for immune memory, vaccination, and reactivation disease
    • Uzonna J.E., Wei G., Yurkowski D., and Bretscher P. Immune elimination of Leishmania major in mice: implications for immune memory, vaccination, and reactivation disease. J. Immunol. 167 (2001) 6967-6974
    • (2001) J. Immunol. , vol.167 , pp. 6967-6974
    • Uzonna, J.E.1    Wei, G.2    Yurkowski, D.3    Bretscher, P.4
  • 40
    • 33947413426 scopus 로고    scopus 로고
    • Immunology of cutaneous leishmaniasis: the role of mast cells, phagocytes and dendritic cells for protective immunity
    • Von Stebut E. Immunology of cutaneous leishmaniasis: the role of mast cells, phagocytes and dendritic cells for protective immunity. Eur. J. Dermatol. 17 (2007) 115-122
    • (2007) Eur. J. Dermatol. , vol.17 , pp. 115-122
    • Von Stebut, E.1
  • 41
    • 0027200941 scopus 로고
    • Targeted activation of CD8+ T cells and infection of b-2 microglobulin deficient mice fail to confirm a primary protective role for CD8 cells in experimental leishmaniasis
    • Wang Z.E., Reiner S.L., Hatam F., Heinzel F.P., Bouvier J., Turck C.W., and Locksley R.M. Targeted activation of CD8+ T cells and infection of b-2 microglobulin deficient mice fail to confirm a primary protective role for CD8 cells in experimental leishmaniasis. J. Immunol. 151 (1993) 2077-2086
    • (1993) J. Immunol. , vol.151 , pp. 2077-2086
    • Wang, Z.E.1    Reiner, S.L.2    Hatam, F.3    Heinzel, F.P.4    Bouvier, J.5    Turck, C.W.6    Locksley, R.M.7
  • 42
    • 0023847926 scopus 로고
    • Cells process exogenous proteins for recognition by cytotoxic T lymphocytes
    • Yewdell J.W., Bennink J.R., and Hosaka Y. Cells process exogenous proteins for recognition by cytotoxic T lymphocytes. Science 239 (1988) 637-640
    • (1988) Science , vol.239 , pp. 637-640
    • Yewdell, J.W.1    Bennink, J.R.2    Hosaka, Y.3
  • 43
    • 0035399848 scopus 로고    scopus 로고
    • Not such a dismal science: the economics of protein synthesis, folding, degradation and antigen processing
    • Yewdell J.W. Not such a dismal science: the economics of protein synthesis, folding, degradation and antigen processing. Trends Cell. Biol. 11 (2001) 294-297
    • (2001) Trends Cell. Biol. , vol.11 , pp. 294-297
    • Yewdell, J.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.