메뉴 건너뛰기




Volumn 136, Issue 12, 2009, Pages 1621-1632

Radiation-attenuated schistosome vaccination a brief historical perspective

Author keywords

Membrane antigens; Radiation attenuation; Schistosomiasis; Secreted antigens; Vaccine development

Indexed keywords

DICTYOCAULUS VACCINE; GAMMA INTERFERON; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 12; PARASITE ANTIGEN; PRAZIQUANTEL; PROTEIN P40; SCHISTOSOMA VACCINE; SM29 PROTEIN; TETRASPANIN; UNCLASSIFIED DRUG;

EID: 70350566623     PISSN: 00311820     EISSN: 14698161     Source Type: Journal    
DOI: 10.1017/S0031182009005848     Document Type: Review
Times cited : (42)

References (131)
  • 1
    • 0009615711 scopus 로고    scopus 로고
    • Developmental di.erences determine larval susceptibility to nitric oxide-mediated killing in a murine model of vaccination against Schistosoma mansoni
    • Ahmed, S. F., Oswald, I. P., Caspar, P., Hieny, S., Keefer, L., Sher, A. and James, S. L. (1997). Developmental di.erences determine larval susceptibility to nitric oxide-mediated killing in a murine model of vaccination against Schistosoma mansoni. Infection and Immunity 65, 219-226.
    • (1997) Infection and Immunity , vol.65 , pp. 219-226
    • Ahmed, S.F.1    Oswald, I.P.2    Caspar, P.3    Hieny, S.4    Keefer, L.5    Sher, A.6    James, S.L.7
  • 2
    • 0032945211 scopus 로고    scopus 로고
    • The radiation-attenuated schistosome vaccine induces high levels of protective immunity in the absence of B cells
    • Anderson, S., Coulson, P. S., Ljubojevic, S., Mountford, A. P. and Wilson, R. A. (1999). The radiation-attenuated schistosome vaccine induces high levels of protective immunity in the absence of B cells. Immunology 96, 22-28.
    • (1999) Immunology , vol.96 , pp. 22-28
    • Anderson, S.1    Coulson, P.S.2    Ljubojevic, S.3    Mountford, A.P.4    Wilson, R.A.5
  • 3
    • 0015951114 scopus 로고
    • Three classes and four (sub)classes of rat immunoglobulins: IgM, IgA, IgE and IgG1, IgG2a, IgG2b, IgG2c
    • Bazin, H., Beckers, A. and Querinjean, P. (1974). Three classes and four (sub)classes of rat immunoglobulins: IgM, IgA, IgE and IgG1, IgG2a, IgG2b, IgG2c. European Journal of Immunology 4, 44-48.
    • (1974) European Journal of Immunology , vol.4 , pp. 44-48
    • Bazin, H.1    Beckers, A.2    Querinjean, P.3
  • 4
    • 0032030745 scopus 로고    scopus 로고
    • Schistosomiasis vaccine: Research to development
    • Bergquist, N. R. and Colley, D. G. (1998). Schistosomiasis vaccine: research to development. Parasitology Today 14, 99-104.
    • (1998) Parasitology Today , vol.14 , pp. 99-104
    • Bergquist, N.R.1    Colley, D.G.2
  • 5
    • 13944260196 scopus 로고    scopus 로고
    • Vaccine-linked chemotherapy: Can schistosomiasis control benefit from an integrated approach?
    • Bergquist, N. R., Leonardo, L. R. and Mitchell, G. F. (2005). Vaccine-linked chemotherapy: can schistosomiasis control benefit from an integrated approach? Trends in Parasitology 21, 112-117.
    • (2005) Trends in Parasitology , vol.21 , pp. 112-117
    • Bergquist, N.R.1    Leonardo, L.R.2    Mitchell, G.F.3
  • 6
    • 44749094854 scopus 로고    scopus 로고
    • Can schistosomiasis really be consigned to history without a vaccine?
    • Bethony, J. M., Diemert, D. J., Oliveira, S. C. and Loukas, A. (2008). Can schistosomiasis really be consigned to history without a vaccine? Vaccine 26, 3373-3376.
    • (2008) Vaccine , vol.26 , pp. 3373-3376
    • Bethony, J.M.1    Diemert, D.J.2    Oliveira, S.C.3    Loukas, A.4
  • 7
    • 0018405048 scopus 로고
    • Factors a.ecting the acquisition of resistance against Schistosoma mansoni in the mouse: III. the failure of primary infections with cercariae of one sex to induce resistance to reinfection
    • Bickle, Q., Bain, J., McGregor, A. and Doenho., M. (1979a). Factors a.ecting the acquisition of resistance against Schistosoma mansoni in the mouse: III. The failure of primary infections with cercariae of one sex to induce resistance to reinfection. Transactions of the Royal Society of Tropical Medicine and Hygiene 73, 37-41.
    • (1979) Transactions of the Royal Society of Tropical Medicine and Hygiene , vol.73 , pp. 37-41
    • Bickle, Q.1    Bain, J.2    McGregor, A.3    Doenho., M.4
  • 8
    • 0021948406 scopus 로고
    • Resistance against Schistosoma mansoni induced by highly irradiated infections : SStudies on species specificity of immunization and attempts to transfer resistance
    • Bickle, Q. D., Andrews, B. J., Doenho., M. J., Ford, M. J. and Taylor, M. G. (1985). Resistance against Schistosoma mansoni induced by highly irradiated infections : studies on species specificity of immunization and attempts to transfer resistance. Parasitology 90, 301-312.
    • (1985) Parasitology , vol.90 , pp. 301-312
    • Bickle, Q.D.1    Andrews, B.J.2    Doenho, M.J.3    Ford, M.J.4    Taylor, M.G.5
  • 9
    • 0022655947 scopus 로고
    • Schistosoma mansoni: Characterization of two protective monoclonal antibodies
    • Bickle, Q. D., Andrews, B. J. and Taylor, M. G. (1986). Schistosoma mansoni: characterization of two protective monoclonal antibodies. Parasite Immunology 8, 95-107.
    • (1986) Parasite Immunology , vol.8 , pp. 95-107
    • Bickle, Q.D.1    Andrews, B.J.2    Taylor, M.G.3
  • 10
    • 0018674945 scopus 로고
    • The effects of gamma-irradiation on migration and survival of Schistosoma mansoni schistosomula in mice
    • Bickle, Q. D., Dobinson, T. and James, E. R. (1979b). The effects of gamma-irradiation on migration and survival of Schistosoma mansoni schistosomula in mice. Parasitology 79, 223-230.
    • (1979) Parasitology , vol.79 , pp. 223-230
    • Bickle, Q.D.1    Dobinson, T.2    James, E.R.3
  • 11
    • 0019961409 scopus 로고
    • Studies on the surface antigenicity and susceptibility to antibodydependent killing of developing schistosomula using sera from chronically infected mice and mice vaccinated with irradiated cercariae
    • Bickle, Q. D. and Ford, M. J. (1982). Studies on the surface antigenicity and susceptibility to antibodydependent killing of developing schistosomula using sera from chronically infected mice and mice vaccinated with irradiated cercariae. Journal of Immunology 128, 2101-2106.
    • (1982) Journal of Immunology , vol.128 , pp. 2101-2106
    • Bickle, Q.D.1    Ford, M.J.2
  • 12
    • 0033045504 scopus 로고    scopus 로고
    • Characterization of a stage-specific Mr 16000 schistosomular surface glycoprotein antigen of Schistosoma mansoni
    • Bickle, Q. D. and Oldridge, J. (1999). Characterization of a stage-specific Mr16000 schistosomular surface glycoprotein antigen of Schistosoma mansoni. Molecular and Biochemical Parasitology 100, 85-94.
    • (1999) Molecular and Biochemical Parasitology , vol.100 , pp. 85-94
    • Bickle, Q.D.1    Oldridge, J.2
  • 13
    • 0018696559 scopus 로고
    • Immunization of mice with gamma-irradiated intramuscularly injected schistosomula of Schistosoma mansoni
    • Bickle, Q. D., Taylor, M. G., Doenho., M. J. and Nelson, G. S. (1979c). Immunization of mice with gamma-irradiated intramuscularly injected schistosomula of Schistosoma mansoni. Parasitology 79, 209-222.
    • (1979) Parasitology , vol.79 , pp. 209-222
    • Bickle, Q.D.1    Taylor, M.G.2    Doenho, M.J.3    Nelson, G.S.4
  • 14
    • 0018403420 scopus 로고
    • Further observations on immunization of sheep against Schistosoma mansoni and S. bovis using irradiationattenuated schistosomula of homologous and heterologous species
    • Bickle, Q. D., Taylor, M. G., James, E. R., Nelson, G. S., Hussein, M. F., Andrews, B. J., Dobinson, A. R. and Marshall, T. F. (1979d). Further observations on immunization of sheep against Schistosoma mansoni and S. bovis using irradiationattenuated schistosomula of homologous and heterologous species. Parasitology 78, 185-193.
    • (1979) Parasitology , vol.78 , pp. 185-193
    • Bickle, Q.D.1    Taylor, M.G.2    James, E.R.3    Nelson, G.S.4    Hussein, M.F.5    Andrews, B.J.6    Dobinson, A.R.7    Marshall, T.F.8
  • 15
    • 33846418019 scopus 로고    scopus 로고
    • Proteomic analysis of the schistosome tegument and its surface membranes
    • Braschi, S., Borges, W. C. and Wilson, R. A. (2006). Proteomic analysis of the schistosome tegument and its surface membranes. Memórias do Instituto Oswaldo Cruz 101 (Suppl. 1), 205-212.
    • (2006) Memórias Do Instituto Oswaldo Cruz , vol.101 , Issue.SUPPL. 1 , pp. 205-212
    • Braschi, S.1    Borges, W.C.2    Wilson, R.A.3
  • 16
    • 33644696623 scopus 로고    scopus 로고
    • Proteins exposed at the adult schistosome surface revealed by biotinylation
    • Braschi, S. and Wilson, R. A. (2006). Proteins exposed at the adult schistosome surface revealed by biotinylation. Molecular and Cellular Proteomics 5, 347-356.
    • (2006) Molecular and Cellular Proteomics , vol.5 , pp. 347-356
    • Braschi, S.1    Wilson, R.A.2
  • 17
    • 0018165707 scopus 로고
    • Immunization of calves against Schistosoma bovis using irradiated cercariae of schistosomula of S. bovis
    • Bushara, H. O., Hussein, M. F., Saad, A. M., Taylor, M. G., Dargie, J. D., Marshall, T. F. and Nelson, G. S. (1978). Immunization of calves against Schistosoma bovis using irradiated cercariae of schistosomula of S. bovis. Parasitology 77, 303-311.
    • (1978) Parasitology , vol.77 , pp. 303-311
    • Bushara, H.O.1    Hussein, M.F.2    Saad, A.M.3    Taylor, M.G.4    Dargie, J.D.5    Marshall, T.F.6    Nelson, G.S.7
  • 19
    • 0025975378 scopus 로고
    • Comparison of Th1- and Th2- associated immune reactivities stimulated by single versus multiple vaccination of mice with irradiated Schistosoma mansoni cercariae
    • Caulada-Benedetti, Z., Al-Zamel, F., Sher, A. and James, S. (1991). Comparison of Th1- and Th2- associated immune reactivities stimulated by single versus multiple vaccination of mice with irradiated Schistosoma mansoni cercariae. Journal of Immunology 146, 1655-1660.
    • (1991) Journal of Immunology , vol.146 , pp. 1655-1660
    • Caulada-Benedetti, Z.1    Al-Zamel, F.2    Sher, A.3    James, S.4
  • 20
    • 0025125389 scopus 로고
    • Phenotypic analysis of the cellular responses in regional lymphoid organs of mice vaccinated against Schistosoma mansoni
    • Constant, S. L., Mountford, A. P. and Wilson, R. A. (1990). Phenotypic analysis of the cellular responses in regional lymphoid organs of mice vaccinated against Schistosoma mansoni. Parasitology 101, 15-22.
    • (1990) Parasitology , vol.101 , pp. 15-22
    • Constant, S.L.1    Mountford, A.P.2    Wilson, R.A.3
  • 21
    • 0030769565 scopus 로고    scopus 로고
    • The radiation-attenuated vaccine against schistosomes in animal models: Paradigm for a human vaccine?
    • Coulson, P. S. (1997). The radiation-attenuated vaccine against schistosomes in animal models: paradigm for a human vaccine? Advances in Parasitology 39, 271-336.
    • (1997) Advances in Parasitology , vol.39 , pp. 271-336
    • Coulson, P.S.1
  • 22
    • 0024462786 scopus 로고
    • Fate of attenuated schistosomula administered to mice by different routes, relative to the immunity induced against Schistosoma mansoni
    • Coulson, P. S. and Mountford, A. P. (1989). Fate of attenuated schistosomula administered to mice by different routes, relative to the immunity induced against Schistosoma mansoni. Parasitology 99, 39-45.
    • (1989) Parasitology , vol.99 , pp. 39-45
    • Coulson, P.S.1    Mountford, A.P.2
  • 23
    • 0031940551 scopus 로고    scopus 로고
    • Nitric oxide produced in the lungs of mice immunized with the radiation-attenuated schistosome vaccine is not the major agent causing challenge parasite elimination
    • Coulson, P. S., Smythies, L. E., Betts, C., Mabbott, N. A., Sternberg, J. M., Wei, X. G., Liew, F. Y. and Wilson, R. A. (1998). Nitric oxide produced in the lungs of mice immunized with the radiation-attenuated schistosome vaccine is not the major agent causing challenge parasite elimination. Immunology 93, 55-63.
    • (1998) Immunology , vol.93 , pp. 55-63
    • Coulson, P.S.1    Smythies, L.E.2    Betts, C.3    Mabbott, N.A.4    Sternberg, J.M.5    Wei, X.G.6    Liew, F.Y.7    Wilson, R.A.8
  • 24
    • 0023888963 scopus 로고
    • Examination of the mechanisms of pulmonary phase resistance to Schistosoma mansoni in vaccinated mice
    • Coulson, P. S. and Wilson, R. A. (1988). Examination of the mechanisms of pulmonary phase resistance to Schistosoma mansoni in vaccinated mice. American Journal of Tropical Medicine and Hygiene 38, 529-539.
    • (1988) American Journal of Tropical Medicine and Hygiene , vol.38 , pp. 529-539
    • Coulson, P.S.1    Wilson, R.A.2
  • 25
    • 0031025737 scopus 로고    scopus 로고
    • Recruitment of lymphocytes to the lung through vaccination enhances the immunity of mice exposed to irradiated schistosomes
    • Coulson, P. S. and Wilson, R. A. (1997). Recruitment of lymphocytes to the lung through vaccination enhances the immunity of mice exposed to irradiated schistosomes. Infection and Immunity 65, 42-48.
    • (1997) Infection and Immunity , vol.65 , pp. 42-48
    • Coulson, P.S.1    Wilson, R.A.2
  • 26
    • 0022570992 scopus 로고
    • The role of pulmonary cellular reactions in the resistance of vaccinated mice to Schistosoma mansoni
    • Crabtree, J. E. and Wilson, R. A. (1986). The role of pulmonary cellular reactions in the resistance of vaccinated mice to Schistosoma mansoni. Parasite Immunology 8, 265-285.
    • (1986) Parasite Immunology , vol.8 , pp. 265-285
    • Crabtree, J.E.1    Wilson, R.A.2
  • 27
    • 2642675458 scopus 로고
    • Cloning of a cDNA encoding a surface antigen of Schistosoma mansoni schistosomula recognized by sera of vaccinated mice
    • Dalton, J. P., Tom, T. D. and Strand, M. (1987). Cloning of a cDNA encoding a surface antigen of Schistosoma mansoni schistosomula recognized by sera of vaccinated mice. Proceedings of the National Academy of Sciences, USA 84, 4268-4272.
    • (1987) Proceedings of the National Academy of Sciences, USA , vol.84 , pp. 4268-4272
    • Dalton, J.P.1    Tom, T.D.2    Strand, M.3
  • 28
    • 0020631567 scopus 로고
    • Schistosoma and related genera: Acquired resistance in mice
    • Dean, D. A. (1983). Schistosoma and related genera: acquired resistance in mice. Experimental Parasitology 55, 1-104.
    • (1983) Experimental Parasitology , vol.55 , pp. 1-104
    • Dean, D.A.1
  • 29
    • 0019454337 scopus 로고
    • Resistance induced by normal and irradiated Schistosoma mansoni: Ability of various worm stages to serve as inducers and targets in mice
    • Dean, D. A., Cioli, D. and Bukowski, M. A. (1981). Resistance induced by normal and irradiated Schistosoma mansoni: ability of various worm stages to serve as inducers and targets in mice. American Journal of Tropical Medicine and Hygiene 30, 1026-1032.
    • (1981) American Journal of Tropical Medicine and Hygiene , vol.30 , pp. 1026-1032
    • Dean, D.A.1    Cioli, D.2    Bukowski, M.A.3
  • 30
    • 0026760441 scopus 로고
    • Evidence that both normal and immune elimination of Schistosoma mansoni take place at the lung stage of migration prior to parasite death
    • Dean, D. A. and Mangold, B. L. (1992). Evidence that both normal and immune elimination of Schistosoma mansoni take place at the lung stage of migration prior to parasite death. American Journal of Tropical Medicine and Hygiene 47, 238-248.
    • (1992) American Journal of Tropical Medicine and Hygiene , vol.47 , pp. 238-248
    • Dean, D.A.1    Mangold, B.L.2
  • 31
    • 0021351076 scopus 로고
    • Comparison of Schistosoma mansoni migration patterns in normal and irradiated cercaria-immunized mice by means of autoradiographic analysis. Evidence that worm elimination occurs after the skin phase in immunized mice
    • Dean, D. A., Mangold, B. L., Georgi, J. R. and Jacobson, R. H. (1984). Comparison of Schistosoma mansoni migration patterns in normal and irradiated cercaria-immunized mice by means of autoradiographic analysis. Evidence that worm elimination occurs after the skin phase in immunized mice. American Journal of Tropical Medicine and Hygiene 33, 89-96.
    • (1984) American Journal of Tropical Medicine and Hygiene , vol.33 , pp. 89-96
    • Dean, D.A.1    Mangold, B.L.2    Georgi, J.R.3    Jacobson, R.H.4
  • 32
    • 0025129062 scopus 로고
    • Evidence for enhancement of IgG1 subclass expression in mice polyvaccinated with radiation-attenuated cercariae of Schistosoma mansoni and the role of this isotype in serum-transferred immunity
    • Delgado, V. and McLaren, D. J. (1990). Evidence for enhancement of IgG1 subclass expression in mice polyvaccinated with radiation-attenuated cercariae of Schistosoma mansoni and the role of this isotype in serum-transferred immunity. Parasite Immunology 12, 15-32.
    • (1990) Parasite Immunology , vol.12 , pp. 15-32
    • Delgado, V.1    McLaren, D.J.2
  • 34
    • 33750508142 scopus 로고    scopus 로고
    • Schistosomiasis: Challenges for control, treatment and drug resistance
    • DOI 10.1097/01.qco.0000247591.13671.6a, PII 0000143220061200000009
    • Fenwick, A. and Webster, J. P. (2006). Schistosomiasis: challenges for control, treatment and drug resistance. Current Opinion in Infectious Diseases 19, 577-582. (Pubitemid 44665464)
    • (2006) Current Opinion in Infectious Diseases , vol.19 , Issue.6 , pp. 577-582
    • Fenwick, A.1    Webster, J.P.2
  • 35
    • 0021200221 scopus 로고
    • Immunization of rats against Schistosoma mansoni using irradiated cercariae, lung schistosomula and liver-stage worms
    • Ford, M. J., Bickle, Q. D. and Taylor, M. G. (1984a). Immunization of rats against Schistosoma mansoni using irradiated cercariae, lung schistosomula and liver-stage worms. Parasitology 89, 327-344.
    • (1984) Parasitology , vol.89 , pp. 327-344
    • Ford, M.J.1    Bickle, Q.D.2    Taylor, M.G.3
  • 36
    • 0023130790 scopus 로고
    • Immunity to Schistosoma mansoni in congenitally athymic, irradiated and mast cell-depleted rats
    • Ford, M. J., Bickle, Q. D. and Taylor, M. G. (1987a). Immunity to Schistosoma mansoni in congenitally athymic, irradiated and mast cell-depleted rats. Parasitology 94, 313-326.
    • (1987) Parasitology , vol.94 , pp. 313-326
    • Ford, M.J.1    Bickle, Q.D.2    Taylor, M.G.3
  • 37
    • 0021719164 scopus 로고
    • Passive transfer of resistance and the site of immune-dependent elimination of the challenge infection in rats vaccinated with highly irradiated cercariae of Schistosoma mansoni
    • Ford, M. J., Bickle, Q. D., Taylor, M. G. and Andrews, B. J. (1984b). Passive transfer of resistance and the site of immune-dependent elimination of the challenge infection in rats vaccinated with highly irradiated cercariae of Schistosoma mansoni. Parasitology 89, 461-482.
    • (1984) Parasitology , vol.89 , pp. 461-482
    • Ford, M.J.1    Bickle, Q.D.2    Taylor, M.G.3    Andrews, B.J.4
  • 38
    • 0023264045 scopus 로고
    • The isotypes of antibody responsible for the ' late ' passive transfer of immunity in rats vaccinated with highly irradiated cercariae
    • Ford, M. J., Dissous, C., Pierce, R. J., Taylor, M. G., Bickle, Q. D. and Capron, A. (1987b). The isotypes of antibody responsible for the ' late ' passive transfer of immunity in rats vaccinated with highly irradiated cercariae. Parasitology 94, 509-522.
    • (1987) Parasitology , vol.94 , pp. 509-522
    • Ford, M.J.1    Dissous, C.2    Pierce, R.J.3    Taylor, M.G.4    Bickle, Q.D.5    Capron, A.6
  • 39
    • 0026542126 scopus 로고
    • Cloning of a 21.7-kDa vaccine-dominant antigen gene of Schistosoma mansoni reveals an EF hand-like motif
    • Francis, P. and Bickle, Q. (1992). Cloning of a 21.7-kDa vaccine-dominant antigen gene of Schistosoma mansoni reveals an EF hand-like motif. Molecular and Biochemical Parasitology 50, 215-224.
    • (1992) Molecular and Biochemical Parasitology , vol.50 , pp. 215-224
    • Francis, P.1    Bickle, Q.2
  • 40
    • 0031772141 scopus 로고    scopus 로고
    • Schistosome immunology: More questions than answers
    • Hagan, P., Ndhlovu, P. D. and Dunne, D. W. (1998). Schistosome immunology: more questions than answers. Parasitology Today 14, 407-412.
    • (1998) Parasitology Today , vol.14 , pp. 407-412
    • Hagan, P.1    Ndhlovu, P.D.2    Dunne, D.W.3
  • 42
    • 0033034578 scopus 로고    scopus 로고
    • Characterization, cloning and immunogenicity of antigens released by lung-stage larvae of Schistosoma mansoni
    • Harrop, R., Coulson, P. S. and Wilson, R. A. (1999). Characterization, cloning and immunogenicity of antigens released by lung-stage larvae of Schistosoma mansoni. Parasitology 118, 583-594.
    • (1999) Parasitology , vol.118 , pp. 583-594
    • Harrop, R.1    Coulson, P.S.2    Wilson, R.A.3
  • 43
    • 25144432777 scopus 로고    scopus 로고
    • Immunity induced by the radiation-attenuated schistosome vaccine
    • Hewitson, J. P., Hamblin, P. A. and Mountford, A. P. (2005). Immunity induced by the radiation-attenuated schistosome vaccine. Parasite Immunology 27, 271-280.
    • (2005) Parasite Immunology , vol.27 , pp. 271-280
    • Hewitson, J.P.1    Hamblin, P.A.2    Mountford, A.P.3
  • 44
    • 34447293089 scopus 로고    scopus 로고
    • In the absence of CD154, administration of interleukin-12 restores Th1 responses but not protective immunity to Schistosoma mansoni
    • Hewitson, J. P., Hamblin, P. A. and Mountford, A. P. (2007). In the absence of CD154, administration of interleukin-12 restores Th1 responses but not protective immunity to Schistosoma mansoni. Infection and Immunity 75, 3539-3547.
    • (2007) Infection and Immunity , vol.75 , pp. 3539-3547
    • Hewitson, J.P.1    Hamblin, P.A.2    Mountford, A.P.3
  • 45
    • 0033566010 scopus 로고    scopus 로고
    • Studies with double cytokinede .cient mice reveal that highly polarized Th1- and Th2-type cytokine and antibody responses contribute equally to vaccine-induced immunity to Schistosoma mansoni
    • Hoffmann, K. F., James, S. L., Cheever, A. W. and Wynn, T. A. (1999). Studies with double cytokinede .cient mice reveal that highly polarized Th1- and Th2-type cytokine and antibody responses contribute equally to vaccine-induced immunity to Schistosoma mansoni. Journal of Immunology 163, 927-938.
    • (1999) Journal of Immunology , vol.163 , pp. 927-938
    • Hoffmann, K.F.1    James, S.L.2    Cheever, A.W.3    Wynn, T.A.4
  • 46
    • 0013473127 scopus 로고
    • Immunization against Schistosoma japonicum in rhesus monkeys produced by irradiated cercariae
    • London
    • Hsu, H. F., Hsu, S. Y. and Osborne, J. W. (1962). Immunization against Schistosoma japonicum in rhesus monkeys produced by irradiated cercariae. Nature, London 194, 98-99.
    • (1962) Nature , vol.194 , pp. 98-99
    • Hsu, H.F.1    Hsu, S.Y.2    Osborne, J.W.3
  • 47
    • 0019797251 scopus 로고
    • Schistosoma mansoni: Vaccination of mice with highly x-irradiated cercariae
    • Hsu, S. Y., Hsu, H. F. and Burmeister, L. F. (1981). Schistosoma mansoni: vaccination of mice with highly x-irradiated cercariae. Experimental Parasitology 52, 91-104.
    • (1981) Experimental Parasitology , vol.52 , pp. 91-104
    • Hsu, S.Y.1    Hsu, H.F.2    Burmeister, L.F.3
  • 48
    • 0014578824 scopus 로고
    • Immunization of rhesus monkeys against schistosome infection by cercariae exposed to high doses of x-radiation
    • Hsu, S. Y., Hsu, H. F. and Osborn, J. W. (1969). Immunization of rhesus monkeys against schistosome infection by cercariae exposed to high doses of x-radiation. Proceedings of the Society of Experimental Biology and Medicine 131, 1146-1149.
    • (1969) Proceedings of the Society of Experimental Biology and Medicine , vol.131 , pp. 1146-1149
    • Hsu, S.Y.1    Hsu, H.F.2    Osborn, J.W.3
  • 50
    • 0031848298 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase-deficient mice develop enhanced type 1 cytokine-associated cellular and humoral immune responses after vaccination with attenuated Schistosoma mansoni cercariae but display partially reduced resistance
    • James, S. L., Cheever, A. W., Caspar, P. and Wynn, T. A. (1998). Inducible nitric oxide synthase-deficient mice develop enhanced type 1 cytokine-associated cellular and humoral immune responses after vaccination with attenuated Schistosoma mansoni cercariae but display partially reduced resistance. Infection and Immunity 66, 3510-3518.
    • (1998) Infection and Immunity , vol.66 , pp. 3510-3518
    • James, S.L.1    Cheever, A.W.2    Caspar, P.3    Wynn, T.A.4
  • 51
    • 0019816287 scopus 로고
    • Mechanisms of protective immunity against Schistosoma mansoni infection in mice vaccinated with irradiated cercariae. I. Analysis of antibody and T-lymphocyte responses in mouse strains developing differing levels of immunity
    • James, S. L., Labine, M. and Sher, A. (1981). Mechanisms of protective immunity against Schistosoma mansoni infection in mice vaccinated with irradiated cercariae. I. Analysis of antibody and T-lymphocyte responses in mouse strains developing differing levels of immunity. Cellular Immunology 65, 75-83.
    • (1981) Cellular Immunology , vol.65 , pp. 75-83
    • James, S.L.1    Labine, M.2    Sher, A.3
  • 52
    • 0021934681 scopus 로고
    • Induction of protective immunity against Schistosoma mansoni by a non living vaccine. I. Partial characterization of antigens recognized by antibodies from mice immunized with soluble schistosome extracts
    • James, S. L., Pearce, E. J. and Sher, A. (1985). Induction of protective immunity against Schistosoma mansoni by a non living vaccine. I. Partial characterization of antigens recognized by antibodies from mice immunized with soluble schistosome extracts. Journal of Immunology 134, 3432-3438.
    • (1985) Journal of Immunology , vol.134 , pp. 3432-3438
    • James, S.L.1    Pearce, E.J.2    Sher, A.3
  • 53
    • 0021015132 scopus 로고
    • Mechanisms of protective immunity against Schistosoma mansoni infection in mice vaccinated with irradiated cercariae III. Identification of a mouse strain, P/N, that fails to respond to vaccination
    • James, S. L. and Sher, A. (1983). Mechanisms of protective immunity against Schistosoma mansoni infection in mice vaccinated with irradiated cercariae III. Identification of a mouse strain, P/N, that fails to respond to vaccination. Parasite Immunology 5, 567-575.
    • (1983) Parasite Immunology , vol.5 , pp. 567-575
    • James, S.L.1    Sher, A.2
  • 54
    • 0032909393 scopus 로고    scopus 로고
    • Optimal vaccination against Schistosoma mansoni requires the induction of both B cell- and IFN-gamma-dependent effector mechanisms
    • Jankovic, D., Wynn, T. A., Kullberg, M. C., Hieny, S., Caspar, P., James, S., Cheever, A. W. and Sher, A. (1999). Optimal vaccination against Schistosoma mansoni requires the induction of both B cell- and IFN-gamma-dependent effector mechanisms. Journal of Immunology 162, 345-351.
    • (1999) Journal of Immunology , vol.162 , pp. 345-351
    • Jankovic, D.1    Wynn, T.A.2    Kullberg, M.C.3    Hieny, S.4    Caspar, P.5    James, S.6    Cheever, A.W.7    Sher, A.8
  • 56
    • 0024544257 scopus 로고
    • The ability of fractionated sera from animals vaccinated with irradiated cercariae of Schistosoma mansoni to transfer immunity to mice
    • Jwo, J. and LoVerde, P. T. (1989). The ability of fractionated sera from animals vaccinated with irradiated cercariae of Schistosoma mansoni to transfer immunity to mice. Journal of Parasitology 75, 252-260.
    • (1989) Journal of Parasitology , vol.75 , pp. 252-260
    • Jwo, J.1    Loverde, P.T.2
  • 57
    • 34250685691 scopus 로고    scopus 로고
    • Should a new tuberculosis vaccine be administered intranasally ?
    • Kallenius, G., Pawlowski, A., Brandtzaeg, P. and Svenson, S. (2007). Should a new tuberculosis vaccine be administered intranasally ? Tuberculosis 87, 257-266.
    • (2007) Tuberculosis , vol.87 , pp. 257-266
    • Kallenius, G.1    Pawlowski, A.2    Brandtzaeg, P.3    Svenson, S.4
  • 58
    • 0023204784 scopus 로고
    • Schistosoma mansoni: Autoradiographic tracking studies of isotopically-labelled challenge parasites in naive and vaccinated CBA/Ca mice
    • Kamiya, H., Smithers, S. R. and McLaren, D. J. (1987). Schistosoma mansoni: autoradiographic tracking studies of isotopically-labelled challenge parasites in naive and vaccinated CBA/Ca mice. Parasite Immunology 9, 515-529.
    • (1987) Parasite Immunology , vol.9 , pp. 515-529
    • Kamiya, H.1    Smithers, S.R.2    McLaren, D.J.3
  • 61
    • 0026781946 scopus 로고
    • Combined microautoradiographic and histopathologic analysis of the fate of challenge Schistosoma mansoni schistosomula in mice immunized with irradiated cercariae
    • Kassim, O. O., Dean, D. A., Mangold, B. L. and Von Lichtenberg, F. (1992). Combined microautoradiographic and histopathologic analysis of the fate of challenge Schistosoma mansoni schistosomula in mice immunized with irradiated cercariae. American Journal of Tropical Medicine and Hygiene 47, 231-237.
    • (1992) American Journal of Tropical Medicine and Hygiene , vol.47 , pp. 231-237
    • Kassim, O.O.1    Dean, D.A.2    Mangold, B.L.3    Von Lichtenberg, F.4
  • 62
    • 0023905148 scopus 로고
    • In vivo effects of monoclonal anti-L3T4 antibody on immune responsiveness of mice infected with Schistosoma mansoni. Reduction of irradiated cercariae-induced resistance
    • Kelly, E. A. and Colley, D. G. (1988). In vivo effects of monoclonal anti-L3T4 antibody on immune responsiveness of mice infected with Schistosoma mansoni. Reduction of irradiated cercariae-induced resistance. Journal of Immunology 140, 2737-2745.
    • (1988) Journal of Immunology , vol.140 , pp. 2737-2745
    • Kelly, E.A.1    Colley, D.G.2
  • 63
    • 0027191328 scopus 로고
    • Mechanisms involved in the loss of antibody-mediated adherence of macrophages to lung-stage schistosomula of Schistosoma mansoni in vitro
    • Lawson, B. W., Bickle, Q. D. and Taylor, M. G. (1993). Mechanisms involved in the loss of antibody-mediated adherence of macrophages to lung-stage schistosomula of Schistosoma mansoni in vitro. Parasitology 106, 463-469.
    • (1993) Parasitology , vol.106 , pp. 463-469
    • Lawson, B.W.1    Bickle, Q.D.2    Taylor, M.G.3
  • 64
    • 0019958111 scopus 로고
    • Regional and splenic lymphocyte proliferative responses of mice exposed to normal or irradiated Schistosoma mansoni cercariae
    • Lewis, F. A. and Wilson, E. M. (1982). Regional and splenic lymphocyte proliferative responses of mice exposed to normal or irradiated Schistosoma mansoni cercariae. American Journal of Tropical Medicine and Hygiene 31, 505-513.
    • (1982) American Journal of Tropical Medicine and Hygiene , vol.31 , pp. 505-513
    • Lewis, F.A.1    Wilson, E.M.2
  • 67
    • 0021175635 scopus 로고
    • The migration and survival of gamma-irradiated Schistosoma mansoni larvae and the duration of host-parasite contact in relation to the induction of resistance in mice
    • Mangold, B. L. and Dean, D. A. (1984). The migration and survival of gamma-irradiated Schistosoma mansoni larvae and the duration of host-parasite contact in relation to the induction of resistance in mice. Parasitology 88, 249-265.
    • (1984) Parasitology , vol.88 , pp. 249-265
    • Mangold, B.L.1    Dean, D.A.2
  • 68
    • 0022627669 scopus 로고
    • Passive transfer with serum and IgG antibodies of irradiated cercariainduced resistance against Schistosoma mansoni in mice
    • Mangold, B. L. and Dean, D. A. (1986). Passive transfer with serum and IgG antibodies of irradiated cercariainduced resistance against Schistosoma mansoni in mice. Journal of Immunology 136, 2644-2648.
    • (1986) Journal of Immunology , vol.136 , pp. 2644-2648
    • Mangold, B.L.1    Dean, D.A.2
  • 69
    • 0027076319 scopus 로고
    • The role of IgG antibodies from irradiated cercaria-immunized rabbits in the passive transfer of immunity to Schistosoma mansoni-infected mice
    • Mangold, B. L. and Dean, D. A. (1992). The role of IgG antibodies from irradiated cercaria-immunized rabbits in the passive transfer of immunity to Schistosoma mansoni-infected mice. American Journal of Tropical Medicine and Hygiene 47, 821-829.
    • (1992) American Journal of Tropical Medicine and Hygiene , vol.47 , pp. 821-829
    • Mangold, B.L.1    Dean, D.A.2
  • 70
    • 0022502890 scopus 로고
    • Site requirements and kinetics of immune-dependent elimination of intravascularly administered lung stage schistosomula in mice immunized with highly irradiated cercariae of Schistosoma mansoni
    • Mangold, B. L., Dean, D. A., Coulson, P. S. and Wilson, R. A. (1986). Site requirements and kinetics of immune-dependent elimination of intravascularly administered lung stage schistosomula in mice immunized with highly irradiated cercariae of Schistosoma mansoni. American Journal of Tropical Medicine and Hygiene 35, 332-344.
    • (1986) American Journal of Tropical Medicine and Hygiene , vol.35 , pp. 332-344
    • Mangold, B.L.1    Dean, D.A.2    Coulson, P.S.3    Wilson, R.A.4
  • 71
    • 0019812295 scopus 로고
    • Host protective humoral immune responses to Schistosoma mansoni infections in the rat. Kinetics of hyperimmune serumdependent sensitivity and elimination of schistosomes in a passive transfer system
    • Mangold, B. L. and Knopf, P. M. (1981). Host protective humoral immune responses to Schistosoma mansoni infections in the rat. Kinetics of hyperimmune serumdependent sensitivity and elimination of schistosomes in a passive transfer system. Parasitology 83, 559-574.
    • (1981) Parasitology , vol.83 , pp. 559-574
    • Mangold, B.L.1    Knopf, P.M.2
  • 72
    • 0022363077 scopus 로고
    • An ultrastructural examination of irradiated, immunizing schistosomula of Schistosoma mansoni during their extended stay in the lungs
    • Mastin, A., Bickle, Q. D. and Wilson, R. A. (1985). An ultrastructural examination of irradiated, immunizing schistosomula of Schistosoma mansoni during their extended stay in the lungs. Parasitology 91, 101-110.
    • (1985) Parasitology , vol.91 , pp. 101-110
    • Mastin, A.1    Bickle, Q.D.2    Wilson, R.A.3
  • 73
    • 84971942702 scopus 로고
    • Schistosoma mansoni: Migration and attrition of irradiated and challenge schistosomula in the mouse
    • Mastin, A. J., Bickle, Q. D. and Wilson, R. A. (1983). Schistosoma mansoni: migration and attrition of irradiated and challenge schistosomula in the mouse. Parasitology 87, 87-102.
    • (1983) Parasitology , vol.87 , pp. 87-102
    • Mastin, A.J.1    Bickle, Q.D.2    Wilson, R.A.3
  • 74
    • 0021964721 scopus 로고
    • Site potential for challenge attrition in mice, rats and guinea pigs vaccinated with irradiated cercariae of Schistosoma mansoni
    • McLaren, D. J., Pearce, E. J. and Smithers, S. R. (1985). Site potential for challenge attrition in mice, rats and guinea pigs vaccinated with irradiated cercariae of Schistosoma mansoni. Parasite Immunology 7, 29-44.
    • (1985) Parasite Immunology , vol.7 , pp. 29-44
    • McLaren, D.J.1    Pearce, E.J.2    Smithers, S.R.3
  • 75
    • 0021859607 scopus 로고
    • Schistosoma mansoni: Challenge attrition during the lung phase of migration in vaccinated and serum-protected rats
    • McLaren, D. J. and Smithers, S. R. (1985). Schistosoma mansoni: challenge attrition during the lung phase of migration in vaccinated and serum-protected rats. Experimental Parasitology 60, 1-9.
    • (1985) Experimental Parasitology , vol.60 , pp. 1-9
    • McLaren, D.J.1    Smithers, S.R.2
  • 76
    • 0023789339 scopus 로고
    • Serum from CBA/Ca mice vaccinated with irradiated cercariae of Schistosoma mansoni protects naive recipients through the recruitment of cutaneous effector cells
    • McLaren, D. J. and Smithers, S. R. (1988). Serum from CBA/Ca mice vaccinated with irradiated cercariae of Schistosoma mansoni protects naive recipients through the recruitment of cutaneous effector cells. Parasitology 97, 287-302.
    • (1988) Parasitology , vol.97 , pp. 287-302
    • McLaren, D.J.1    Smithers, S.R.2
  • 77
    • 38549179418 scopus 로고    scopus 로고
    • Current status of vaccines for schistosomiasis
    • McManus, D. P. and Loukas, A. (2008). Current status of vaccines for schistosomiasis. Clinical Microbiology Reviews 21, 225-242.
    • (2008) Clinical Microbiology Reviews , vol.21 , pp. 225-242
    • McManus, D.P.1    Loukas, A.2
  • 78
    • 0018062307 scopus 로고
    • Industrial development and field use of the canine hookworm vaccine
    • Miller, T. A. (1978). Industrial development and field use of the canine hookworm vaccine. Advances in Parasitology 16, 333-342.
    • (1978) Advances in Parasitology , vol.16 , pp. 333-342
    • Miller, T.A.1
  • 81
    • 0025353759 scopus 로고
    • Antibody is responsible for the passive transfer of immunity to mice from rabbits, rats or mice vaccinated with attenuated Schistosoma japonicum cercariae
    • Moloney, N. A. and Webbe, G. (1990). Antibody is responsible for the passive transfer of immunity to mice from rabbits, rats or mice vaccinated with attenuated Schistosoma japonicum cercariae. Parasitology 100, 235-239.
    • (1990) Parasitology , vol.100 , pp. 235-239
    • Moloney, N.A.1    Webbe, G.2
  • 82
    • 0018848990 scopus 로고
    • Studies of the antibody-dependent killing of schistosomula of Schistosoma mansoni employing haptenic target antigens. I. Evidence that the loss in susceptibility to immune damage undergone by developing schistosomula involves a change unrelated to the masking of parasite antigens by host molecules
    • Moser, G., Wassom, D. L. and Sher, A. (1980). Studies of the antibody-dependent killing of schistosomula of Schistosoma mansoni employing haptenic target antigens. I. Evidence that the loss in susceptibility to immune damage undergone by developing schistosomula involves a change unrelated to the masking of parasite antigens by host molecules. Journal of Experimental Medicine 152, 41-53.
    • (1980) Journal of Experimental Medicine , vol.152 , pp. 41-53
    • Moser, G.1    Wassom, D.L.2    Sher, A.3
  • 83
    • 0029882942 scopus 로고    scopus 로고
    • Induction of Th1 cell-mediated protective immunity to Schistosoma mansoni by co-administration of larval antigens and IL-12 as an adjuvant
    • Mountford, A. P., Anderson, S. and Wilson, R. A. (1996). Induction of Th1 cell-mediated protective immunity to Schistosoma mansoni by co-administration of larval antigens and IL-12 as an adjuvant. Journal of Immunology 156, 4739-4745.
    • (1996) Journal of Immunology , vol.156 , pp. 4739-4745
    • Mountford, A.P.1    Anderson, S.2    Wilson, R.A.3
  • 84
    • 0026550253 scopus 로고
    • The generation of interferon-gamma-producing T lymphocytes in skin-draining lymph nodes, and their recruitment to the lungs, is associated with protective immunity to Schistosoma mansoni
    • Mountford, A. P., Coulson, P. S., Pemberton, R. M., Smythies, L. E. and Wilson, R. A. (1992). The generation of interferon-gamma-producing T lymphocytes in skin-draining lymph nodes, and their recruitment to the lungs, is associated with protective immunity to Schistosoma mansoni. Immunology 75, 250-256.
    • (1992) Immunology , vol.75 , pp. 250-256
    • Mountford, A.P.1    Coulson, P.S.2    Pemberton, R.M.3    Smythies, L.E.4    Wilson, R.A.5
  • 85
    • 0023813428 scopus 로고
    • Antigen localization and the induction of resistance in mice vaccinated with irradiated cercariae of Schistosoma mansoni
    • Mountford, A. P., Coulson, P. S. and Wilson, R. A. (1988). Antigen localization and the induction of resistance in mice vaccinated with irradiated cercariae of Schistosoma mansoni. Parasitology 97, 11-25.
    • (1988) Parasitology , vol.97 , pp. 11-25
    • Mountford, A.P.1    Coulson, P.S.2    Wilson, R.A.3
  • 86
    • 0031813898 scopus 로고    scopus 로고
    • Failure of P strain mice to respond to vaccination against schistosomiasis correlates with impaired production of IL-12 and up-regulation of Th2 cytokines that inhibit macrophage activation
    • Oswald, I. P., Caspar, P., Wynn, T. A., Scharton- Kersten, T., Williams, M. E., Hieny, S., Sher, A. and James, S. L. (1998). Failure of P strain mice to respond to vaccination against schistosomiasis correlates with impaired production of IL-12 and up-regulation of Th2 cytokines that inhibit macrophage activation. European Journal of Immunology 28, 1762-1772.
    • (1998) European Journal of Immunology , vol.28 , pp. 1762-1772
    • Oswald, I.P.1    Caspar, P.2    Wynn, T.A.3    Scharton- Kersten, T.4    Williams, M.E.5    Hieny, S.6    Sher, A.7    James, S.L.8
  • 87
    • 0022658025 scopus 로고
    • Evidence that the reduced surface antigenicity of developing Schistosoma mansoni schistosomula is due to antigen shedding rather than host molecule acquisition
    • Pearce, E. J., Basch, P. F. and Sher, A. (1986). Evidence that the reduced surface antigenicity of developing Schistosoma mansoni schistosomula is due to antigen shedding rather than host molecule acquisition. Parasite Immunology 8, 79-94.
    • (1986) Parasite Immunology , vol.8 , pp. 79-94
    • Pearce, E.J.1    Basch, P.F.2    Sher, A.3
  • 88
    • 0026060650 scopus 로고
    • Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni
    • Pearce, E. J., Caspar, P., Grzych, J. M., Lewis, F. A. and Sher, A. (1991). Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni. Journal of Experimental Medicine 173, 159-166.
    • (1991) Journal of Experimental Medicine , vol.173 , pp. 159-166
    • Pearce, E.J.1    Caspar, P.2    Grzych, J.M.3    Lewis, F.A.4    Sher, A.5
  • 89
    • 0025765572 scopus 로고
    • Patterns of cytokine production and proliferation by T lymphocytes di.er in mice vaccinated or infected with Schistosoma mansoni
    • Pemberton, R. M., Smythies, L. E., Mountford, A. P. and Wilson, R. A. (1991). Patterns of cytokine production and proliferation by T lymphocytes di.er in mice vaccinated or infected with Schistosoma mansoni. Immunology 73, 327-333.
    • (1991) Immunology , vol.73 , pp. 327-333
    • Pemberton, R.M.1    Smythies, L.E.2    Mountford, A.P.3    Wilson, R.A.4
  • 90
    • 0028957941 scopus 로고
    • T-helper type-1-dominated lymph node responses induced in C57BL/6 mice by optimally irradiated cercariae of Schistosoma mansoni are down-regulated after challenge infection
    • Pemberton, R. M. and Wilson, R. A. (1995). T-helper type-1-dominated lymph node responses induced in C57BL/6 mice by optimally irradiated cercariae of Schistosoma mansoni are down-regulated after challenge infection. Immunology 84, 310-316.
    • (1995) Immunology , vol.84 , pp. 310-316
    • Pemberton, R.M.1    Wilson, R.A.2
  • 91
    • 49749204927 scopus 로고
    • Resistance produced in mice by exposure to irradiated Schistosoma mansoni cercariae
    • Radke, M. G. and Sadun, E. H. (1963). Resistance produced in mice by exposure to irradiated Schistosoma mansoni cercariae. Experimental Parasitology 13, 134-142.
    • (1963) Experimental Parasitology , vol.13 , pp. 134-142
    • Radke, M.G.1    Sadun, E.H.2
  • 92
    • 0026501268 scopus 로고
    • Comparison of irradiated-cercaria schistosome vaccine models that use 15- and 50-kilorad doses: The 15-kilorad dose gives greater protection, smaller liver sizes, and higher gamma interferon levels after challenge
    • Reynolds, S. R. and Harn, D. A. (1992). Comparison of irradiated-cercaria schistosome vaccine models that use 15- and 50-kilorad doses: the 15-kilorad dose gives greater protection, smaller liver sizes, and higher gamma interferon levels after challenge. Infection and Immunity 60, 90-94.
    • (1992) Infection and Immunity , vol.60 , pp. 90-94
    • Reynolds, S.R.1    Harn, D.A.2
  • 93
    • 0027391858 scopus 로고
    • Candidate vaccine antigens identified by antibodies from mice vaccinated with 15- or 50-kilorad-irradiated cercariae of Schistosoma mansoni
    • Richter, D. and Harn, D. A. (1993). Candidate vaccine antigens identi.ed by antibodies from mice vaccinated with 15- or 50-kilorad-irradiated cercariae of Schistosoma mansoni. Infection and Immunity 61, 146-154. (Pubitemid 23015411)
    • (1993) Infection and Immunity , vol.61 , Issue.1 , pp. 146-154
    • Richter, D.1    Harn, D.A.2
  • 94
    • 0027302373 scopus 로고
    • Isotype responses to candidate vaccine antigens in protective sera obtained from mice vaccinated with irradiated cercariae of Schistosoma mansoni
    • Richter, D., Incani, R. N. and Harn, D. A. (1993a). Isotype responses to candidate vaccine antigens in protective sera obtained from mice vaccinated with irradiated cercariae of Schistosoma mansoni. Infection and Immunity 61, 3003-3011. (Pubitemid 23182300)
    • (1993) Infection and Immunity , vol.61 , Issue.7 , pp. 3003-3011
    • Richter, D.1    Incani, R.N.2    Harn, D.A.3
  • 95
    • 0027284178 scopus 로고
    • Candidate vaccine antigens that stimulate the cellular immune response of mice vaccinated with irradiated cercariae of Schistosoma mansoni
    • Richter, D., Reynolds, S. R. and Harn, D. A. (1993b). Candidate vaccine antigens that stimulate the cellular immune response of mice vaccinated with irradiated cercariae of Schistosoma mansoni. Journal of Immunology 151, 256-265. (Pubitemid 23206990)
    • (1993) Journal of Immunology , vol.151 , Issue.1 , pp. 256-265
    • Richter, D.1    Reynolds, S.R.2    Harn, D.A.3
  • 96
    • 56949105868 scopus 로고
    • Parasitologic, pathologic and serologic reactions to Schistosoma mansoni in monkeys exposed to irradiated cercariae
    • Sadun, E. H., Bruce, J. I. and Macomber, P. B. (1964). Parasitologic, pathologic and serologic reactions to Schistosoma mansoni in monkeys exposed to irradiated cercariae. American Journal of Tropical Medicine and Hygiene 13, 548-557.
    • (1964) American Journal of Tropical Medicine and Hygiene , vol.13 , pp. 548-557
    • Sadun, E.H.1    Bruce, J.I.2    MacOmber, P.B.3
  • 97
    • 0020079693 scopus 로고
    • Mechanisms of protective immunity against Schistosoma mansoni infection in mice vaccinated with irradiated cercariae. II. Analysis of immunity in hosts de.cient in T lymphocytes, B lymphocytes, or complement
    • Sher, A., Hieny, S., James, S. L. and Asofsky, R. (1982a). Mechanisms of protective immunity against Schistosoma mansoni infection in mice vaccinated with irradiated cercariae. II. Analysis of immunity in hosts de.cient in T lymphocytes, B lymphocytes, or complement. Journal of Immunology 128, 1880-1884.
    • (1982) Journal of Immunology , vol.128 , pp. 1880-1884
    • Sher, A.1    Hieny, S.2    James, S.L.3    Asofsky, R.4
  • 98
    • 0020063939 scopus 로고
    • Macrophages as effector cells of protective immunity in murine schistosomiasis. III. Loss of susceptibility to macrophage-mediated killing during maturation of S. mansoni schistosomula from the skin to the lung stage
    • Sher, A., James, S. L., Simpson, A. J., Lazdins, J. K. and Meltzer, M. S. (1982b). Macrophages as effector cells of protective immunity in murine schistosomiasis. III. Loss of susceptibility to macrophage-mediated killing during maturation of S. mansoni schistosomula from the skin to the lung stage. Journal of Immunology 128, 1876-1879.
    • (1982) Journal of Immunology , vol.128 , pp. 1876-1879
    • Sher, A.1    James, S.L.2    Simpson, A.J.3    Lazdins, J.K.4    Meltzer, M.S.5
  • 99
    • 0020575013 scopus 로고
    • Identification of surface antigens of schistosomula of Schistosoma mansoni recognized by antibodies from mice immunized by chronic infection and by exposure to highly irradiated cercariae
    • Simpson, A. J., James, S. L. and Sher, A. (1983). Identification of surface antigens of schistosomula of Schistosoma mansoni recognized by antibodies from mice immunized by chronic infection and by exposure to highly irradiated cercariae. Infection and Immunity 41, 591-597.
    • (1983) Infection and Immunity , vol.41 , pp. 591-597
    • Simpson, A.J.1    James, S.L.2    Sher, A.3
  • 100
    • 36949088694 scopus 로고
    • Immunizing Effect of irradiated cercariae of Schistosoma mansoni in rhesus monkeys
    • London
    • Smithers, S. R. (1962). Immunizing Effect of irradiated cercariae of Schistosoma mansoni in rhesus monkeys. Nature, London 194, 1146-1147.
    • (1962) Nature , vol.194 , pp. 1146-1147
    • Smithers, S.R.1
  • 101
    • 15444361408 scopus 로고
    • Immunity to trematode infections
    • (ed. Cohen, E. and Sadun, E. E.), Blackwell Scienti.c Publications, Oxford, UK
    • Smithers, S. R. (1976). Immunity to trematode infections. In Immunology of Parasitic Infections (ed. Cohen, E. and Sadun, E. E.), pp. 296-332. Blackwell Scienti.c Publications, Oxford, UK.
    • (1976) Immunology of Parasitic Infections , pp. 296-332
    • Smithers, S.R.1
  • 102
    • 0013817178 scopus 로고
    • Naturally acquired resistance to experimental infections of Schistosoma mansoni in the rhesus monkey (Macaca mulatta)
    • Smithers, S. R. and Terry, R. J. (1965). Naturally acquired resistance to experimental infections of Schistosoma mansoni in the rhesus monkey (Macaca mulatta). Parasitology 55, 701-710.
    • (1965) Parasitology , vol.55 , pp. 701-710
    • Smithers, S.R.1    Terry, R.J.2
  • 103
    • 0014043140 scopus 로고
    • Resistance to experimental infection with Schistosoma mansoni in rhesus monkeys induced by the transfer of adult worms
    • Smithers, S. R. and Terry, R. J. (1967). Resistance to experimental infection with Schistosoma mansoni in rhesus monkeys induced by the transfer of adult worms. Transactions of the Royal Society of Tropical Medicine and Hygiene 61, 517-533.
    • (1967) Transactions of the Royal Society of Tropical Medicine and Hygiene , vol.61 , pp. 517-533
    • Smithers, S.R.1    Terry, R.J.2
  • 104
    • 0037407602 scopus 로고    scopus 로고
    • Isolation of cDNAs encoding secreted and transmembrane proteins from Schistosoma mansoni by a signal sequence trap method
    • Smyth, D., McManus, D. P., Smout, M. J., Laha, T., Zhang, W. and Loukas, A. (2003). Isolation of cDNAs encoding secreted and transmembrane proteins from Schistosoma mansoni by a signal sequence trap method. Infection and Immunity 71, 2548-2554.
    • (2003) Infection and Immunity , vol.71 , pp. 2548-2554
    • Smyth, D.1    McManus, D.P.2    Smout, M.J.3    Laha, T.4    Zhang, W.5    Loukas, A.6
  • 105
    • 0029835725 scopus 로고    scopus 로고
    • Kinetics and mechanism of effector focus formation in the lungs of mice vaccinated with irradiated cercariae of Schistosoma mansoni
    • Smythies, L. E., Betts, C., Coulson, P. S., Dowling, M. A. and Wilson, R. A. (1996). Kinetics and mechanism of effector focus formation in the lungs of mice vaccinated with irradiated cercariae of Schistosoma mansoni. Parasite Immunology 18, 359-369.
    • (1996) Parasite Immunology , vol.18 , pp. 359-369
    • Smythies, L.E.1    Betts, C.2    Coulson, P.S.3    Dowling, M.A.4    Wilson, R.A.5
  • 106
    • 0026452253 scopus 로고
    • Monoclonal antibody to IFN-gamma modifies pulmonary in.ammatory responses and abrogates immunity to Schistosoma mansoni in mice vaccinated with attenuated cercariae
    • Smythies, L. E., Coulson, P. S. and Wilson, R. A. (1992a). Monoclonal antibody to IFN-gamma modifies pulmonary in.ammatory responses and abrogates immunity to Schistosoma mansoni in mice vaccinated with attenuated cercariae. Journal of Immunology 149, 3654-3658.
    • (1992) Journal of Immunology , vol.149 , pp. 3654-3658
    • Smythies, L.E.1    Coulson, P.S.2    Wilson, R.A.3
  • 107
    • 0026595061 scopus 로고
    • T cell-derived cytokines associated with pulmonary immune mechanisms in mice vaccinated with irradiated cercariae of Schistosoma mansoni
    • Smythies, L. E., Pemberton, R. M., Coulson, P. S., Mountford, A. P. and Wilson, R. A. (1992b). T cell-derived cytokines associated with pulmonary immune mechanisms in mice vaccinated with irradiated cercariae of Schistosoma mansoni. Journal of Immunology 148, 1512-1518.
    • (1992) Journal of Immunology , vol.148 , pp. 1512-1518
    • Smythies, L.E.1    Pemberton, R.M.2    Coulson, P.S.3    Mountford, A.P.4    Wilson, R.A.5
  • 108
    • 0027451467 scopus 로고
    • Protective immunity in baboons vaccinated with a recombinant antigen or radiation-attenuated cercariae of Schistosoma mansoni is antibody-dependent
    • Soisson, L. A., Reid, G. D., Farah, I. O., Nyindo, M. and Strand, M. (1993). Protective immunity in baboons vaccinated with a recombinant antigen or radiation-attenuated cercariae of Schistosoma mansoni is antibody-dependent. Journal of Immunology 151, 4782-4789. (Pubitemid 23318531)
    • (1993) Journal of Immunology , vol.151 , Issue.9 , pp. 4782-4789
    • Soisson, L.A.1    Reid, G.D.F.2    Farah, I.O.3    Nyindo, M.4    Strand, M.5
  • 109
    • 0026458038 scopus 로고
    • Induction of protective immunity in mice using a 62-kDa recombinant fragment of a Schistosoma mansoni surface antigen
    • Soisson, L. M., Masterson, C. P., Tom, T. D., McNally, M. T., Lowell, G. H. and Strand, M. (1992). Induction of protective immunity in mice using a 62-kDa recombinant fragment of a Schistosoma mansoni surface antigen. Journal of Immunology 149, 3612-3620.
    • (1992) Journal of Immunology , vol.149 , pp. 3612-3620
    • Soisson, L.M.1    Masterson, C.P.2    Tom, T.D.3    McNally, M.T.4    Lowell, G.H.5    Strand, M.6
  • 110
    • 0019425277 scopus 로고
    • Attrition of schistosomes in an irradiation-attenuated cercarial immunization model of Schistosoma mansoni
    • Stek, M., Jr., Dean, D. A. and Clark, S. S. (1981a). Attrition of schistosomes in an irradiation-attenuated cercarial immunization model of Schistosoma mansoni. American Journal of Tropical Medicine and Hygiene 30, 1033-1038.
    • (1981) American Journal of Tropical Medicine and Hygiene , vol.30 , pp. 1033-1038
    • Stek Jr., M.1    Dean, D.A.2    Clark, S.S.3
  • 111
    • 0019795955 scopus 로고
    • Immunization of baboons with Schistosoma mansoni cercariae attenuated by gamma irradiation
    • Stek, M. F., Minard, P., Dean, D. A. and Hall, J. E. (1981b). Immunization of baboons with Schistosoma mansoni cercariae attenuated by gamma irradiation. Science 212, 1518-1520.
    • (1981) Science , vol.212 , pp. 1518-1520
    • Stek, M.F.1    Minard, P.2    Dean, D.A.3    Hall, J.E.4
  • 113
    • 0028166374 scopus 로고
    • Schistosomiasis vaccines: Farewell to the God of Plague?
    • Taylor, M. G. (1994). Schistosomiasis vaccines: Farewell to the God of Plague? Journal of Tropical Medicine and Hygiene 97, 257-268.
    • (1994) Journal of Tropical Medicine and Hygiene , vol.97 , pp. 257-268
    • Taylor, M.G.1
  • 114
    • 0017109619 scopus 로고
    • Immunisation of baboons against Schistosoma mansoni using irradiated S. mansoni cercariae and schistosomula and non-irradiated S. rodhaini cercariae
    • Taylor, M. G., James, E. R., Nelson, G. S., Bickle, Q., Andrews, B. J., Dobinson, A. R. and Webbe, G. (1976a). Immunisation of baboons against Schistosoma mansoni using irradiated S. mansoni cercariae and schistosomula and non-irradiated S. rodhaini cercariae. Journal of Helminthology 50, 215-221.
    • (1976) Journal of Helminthology , vol.50 , pp. 215-221
    • Taylor, M.G.1    James, E.R.2    Nelson, G.S.3    Bickle, Q.4    Andrews, B.J.5    Dobinson, A.R.6    Webbe, G.7
  • 115
    • 0017278803 scopus 로고
    • Immunisation of sheep against Schistosoma mattheei using either irradiated cercariae or irradiated schistosomula
    • Taylor, M. G., James, E. R., Nelson, G. S., Bickle, Q., Dunne, D. W. and Webbe, G. (1976b). Immunisation of sheep against Schistosoma mattheei using either irradiated cercariae or irradiated schistosomula. Journal of Helminthology 50, 1-9.
    • (1976) Journal of Helminthology , vol.50 , pp. 1-9
    • Taylor, M.G.1    James, E.R.2    Nelson, G.S.3    Bickle, Q.4    Dunne, D.W.5    Webbe, G.6
  • 117
    • 0023868324 scopus 로고
    • Studies on immunity to Schistosoma mansoni in vivo: Whole-body irradiation has no Effect on vaccine-induced resistance in mice
    • Vignali, D. A., Bickle, Q. D. and Taylor, M. G. (1988a). Studies on immunity to Schistosoma mansoni in vivo: whole-body irradiation has no Effect on vaccine-induced resistance in mice. Parasitology 96, 49-61.
    • (1988) Parasitology , vol.96 , pp. 49-61
    • Vignali, D.A.1    Bickle, Q.D.2    Taylor, M.G.3
  • 118
    • 0023900923 scopus 로고
    • Comparison of the role of complement in immunity to Schistosoma mansoni in rats and mice
    • Vignali, D. A., Bickle, Q. D., Taylor, M. G., Tennent, G. and Pepys, M. B. (1988b). Comparison of the role of complement in immunity to Schistosoma mansoni in rats and mice. Immunology 63, 55-61.
    • (1988) Immunology , vol.63 , pp. 55-61
    • Vignali, D.A.1    Bickle, Q.D.2    Taylor, M.G.3    Tennent, G.4    Pepys, M.B.5
  • 119
    • 0024339790 scopus 로고
    • A role for CD4+ but not CD8+ T cells in immunity to Schistosoma mansoni induced by 20 krad-irradiated and Ro 11-3128-terminated infections
    • Vignali, D. A., Crocker, P., Bickle, Q. D., Cobbold, S., Waldmann, H. and Taylor, M. G. (1989a). A role for CD4+ but not CD8+ T cells in immunity to Schistosoma mansoni induced by 20 krad-irradiated and Ro 11-3128-terminated infections. Immunology 67, 466-472.
    • (1989) Immunology , vol.67 , pp. 466-472
    • Vignali, D.A.1    Crocker, P.2    Bickle, Q.D.3    Cobbold, S.4    Waldmann, H.5    Taylor, M.G.6
  • 120
    • 0024591422 scopus 로고
    • Histological examination of the cellular reactions around schistosomula of Schistosoma mansoni in the lungs of sublethally irradiated and unirradiated, immune and control rats
    • Vignali, D. A., Klaus, S. N., Bickle, Q. D. and Taylor, M. G. (1989b). Histological examination of the cellular reactions around schistosomula of Schistosoma mansoni in the lungs of sublethally irradiated and unirradiated, immune and control rats. Parasitology 98, 57-65.
    • (1989) Parasitology , vol.98 , pp. 57-65
    • Vignali, D.A.1    Klaus, S.N.2    Bickle, Q.D.3    Taylor, M.G.4
  • 121
    • 0009406996 scopus 로고
    • Immunization to Schistosoma mansoni in mice inoculated with radiated cercariae
    • Villella, J. B., Gomberg, H. J. and Gould, S. E. (1961). Immunization to Schistosoma mansoni in mice inoculated with radiated cercariae. Science 134, 1073-1075.
    • (1961) Science , vol.134 , pp. 1073-1075
    • Villella, J.B.1    Gomberg, H.J.2    Gould, S.E.3
  • 123
    • 0020314384 scopus 로고
    • Schistosoma haematobium in the baboon (Papio anubis) : EEffect of vaccination with irradiated larvae on the subsequent infection with percutaneously applied cercariae
    • Webbe, G., Sturrock, R. F., James, E. R. and James, C. (1982). Schistosoma haematobium in the baboon (Papio anubis) : Effect of vaccination with irradiated larvae on the subsequent infection with percutaneously applied cercariae. Transactions of the Royal Society of Tropical Medicine and Hygiene 76, 354-361.
    • (1982) Transactions of the Royal Society of Tropical Medicine and Hygiene , vol.76 , pp. 354-361
    • Webbe, G.1    Sturrock, R.F.2    James, E.R.3    James, C.4
  • 124
    • 0024363962 scopus 로고
    • Lung-phase immunity to Schistosomes: A new perspective on an old problem?
    • Wilson, R. A. and Coulson, P. S. (1989). Lung-phase immunity to Schistosomes: a new perspective on an old problem? Parasitology Today 5, 274-278.
    • (1989) Parasitology Today , vol.5 , pp. 274-278
    • Wilson, R.A.1    Coulson, P.S.2
  • 125
    • 33846462491 scopus 로고    scopus 로고
    • Schistosome vaccines: A critical appraisal
    • Wilson, R. A. and Coulson, P. S. (2006). Schistosome vaccines: a critical appraisal. Memórias do Instituto Oswaldo Cruz 101 (Suppl. 1), 13-20.
    • (2006) Memórias Do Instituto Oswaldo Cruz , vol.101 , Issue.SUPPL. 1 , pp. 13-20
    • Wilson, R.A.1    Coulson, P.S.2
  • 126
    • 0030059935 scopus 로고    scopus 로고
    • Impaired immunity and altered pulmonary responses in mice with a disrupted interferon-gamma receptor gene exposed to the irradiated Schistosoma mansoni vaccine
    • Wilson, R. A., Coulson, P. S., Betts, C., Dowling, M. A. and Smythies, L. E. (1996). Impaired immunity and altered pulmonary responses in mice with a disrupted interferon-gamma receptor gene exposed to the irradiated Schistosoma mansoni vaccine. Immunology 87, 275-282.
    • (1996) Immunology , vol.87 , pp. 275-282
    • Wilson, R.A.1    Coulson, P.S.2    Betts, C.3    Dowling, M.A.4    Smythies, L.E.5
  • 127
    • 0022629262 scopus 로고
    • Migration of the schistosomula of Schistosoma mansoni in mice vaccinated with radiation-attenuated cercariae, and normal mice: An attempt to identify the timing and site of parasite death
    • Wilson, R. A., Coulson, P. S. and Dixon, B. (1986). Migration of the schistosomula of Schistosoma mansoni in mice vaccinated with radiation-attenuated cercariae, and normal mice: an attempt to identify the timing and site of parasite death. Parasitology 92, 101-116.
    • (1986) Parasitology , vol.92 , pp. 101-116
    • Wilson, R.A.1    Coulson, P.S.2    Dixon, B.3
  • 128
    • 0029042649 scopus 로고
    • IL-12 enhances vaccine-induced immunity to Schistosoma mansoni in mice and decreases T helper 2 cytokine expression, IgE production, and tissue eosinophilia
    • Wynn, T. A., Jankovic, D., Hieny, S., Cheever, A. W. and Sher, A. (1995). IL-12 enhances vaccine-induced immunity to Schistosoma mansoni in mice and decreases T helper 2 cytokine expression, IgE production, and tissue eosinophilia. Journal of Immunology 154, 4701-4709.
    • (1995) Journal of Immunology , vol.154 , pp. 4701-4709
    • Wynn, T.A.1    Jankovic, D.2    Hieny, S.3    Cheever, A.W.4    Sher, A.5
  • 129
    • 0028113360 scopus 로고
    • Elevated expression of Th1 cytokines and nitric oxide synthase in the lungs of vaccinated mice after challenge infection with Schistosoma mansoni
    • Wynn, T. A., Oswald, I. P., Eltoum, I. A., Caspar, P., Lowenstein, C. J., Lewis, F. A., James, S. L. and Sher, A. (1994). Elevated expression of Th1 cytokines and nitric oxide synthase in the lungs of vaccinated mice after challenge infection with Schistosoma mansoni. Journal of Immunology 153, 5200-5209.
    • (1994) Journal of Immunology , vol.153 , pp. 5200-5209
    • Wynn, T.A.1    Oswald, I.P.2    Eltoum, I.A.3    Caspar, P.4    Lowenstein, C.J.5    Lewis, F.A.6    James, S.L.7    Sher, A.8
  • 130
    • 0030293445 scopus 로고    scopus 로고
    • IL-12 enhances vaccine-induced immunity to schistosomes by augmenting both humoral and cell-mediated immune responses against the parasite
    • Wynn, T. A., Reynolds, A., James, S., Cheever, A. W., Caspar, P., Hieny, S., Jankovic, D., Strand, M. and Sher, A. (1996). IL-12 enhances vaccine-induced immunity to schistosomes by augmenting both humoral and cell-mediated immune responses against the parasite. Journal of Immunology 157, 4068-4078.
    • (1996) Journal of Immunology , vol.157 , pp. 4068-4078
    • Wynn, T.A.1    Reynolds, A.2    James, S.3    Cheever, A.W.4    Caspar, P.5    Hieny, S.6    Jankovic, D.7    Strand, M.8    Sher, A.9
  • 131
    • 0029874927 scopus 로고    scopus 로고
    • Protection against Schistosoma mansoni and associated immune responses induced in the vervet monkey Cercopithecus aethiops by the irradiated cercaria vaccine
    • Yole, D. S., Reid, G. D. and Wilson, R. A. (1996). Protection against Schistosoma mansoni and associated immune responses induced in the vervet monkey Cercopithecus aethiops by the irradiated cercaria vaccine. American Journal of Tropical Medicine and Hygiene 54, 265-270.
    • (1996) American Journal of Tropical Medicine and Hygiene , vol.54 , pp. 265-270
    • Yole, D.S.1    Reid, G.D.2    Wilson, R.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.