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Volumn 6, Issue 6, 2011, Pages 1358-1361

A BODIPY-based probe for the selective detection of hypochlorous acid in living cells

Author keywords

bioimaging; bodipy; fluorescent probes; hypochlorus acid; reactive oxygen species

Indexed keywords

BIO-IMAGING; BODIPY; FLUORESCENT PROBES; HYPOCHLORUS ACID; REACTIVE OXYGEN SPECIES;

EID: 79957745742     PISSN: 18614728     EISSN: 1861471X     Source Type: Journal    
DOI: 10.1002/asia.201100025     Document Type: Article
Times cited : (117)

References (43)
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    • Angew. Chem. Int. Ed. 2008, 47, 1184-1201.
    • (2008) Angew. Chem. Int. Ed. , vol.47 , pp. 1184-1201
  • 24
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    • F) of probe 2 and parent BODIPY 1 in various solvents are presented in the Supporting Information, Table S1
    • F) of probe 2 and parent BODIPY 1 in various solvents are presented in the Supporting Information, Table S1.
  • 25
    • 79957702851 scopus 로고    scopus 로고
    • note
    • In preparative organic syntheses, the oxidation of thioethers into sulfoxides can be accomplished with many oxidizing agents, including peracids or hydrogen peroxide in the presence of various catalysts. Organic peroxides, such as tert-butyl hydroperoxide have also been widely used as stoichiometric oxidants in such transition-metal-catalyzed reactions. However, in the absence of catalysts, the reaction of hydrogen peroxides or alkyl hydroperoxides is sluggish in aqueous solutions at room temperature and physiological pH. By contrast, HOCl shows sufficient oxidizing power under these conditions for the oxidation to proceed, which helps rationalize the observed selectivity of probe 2. See
  • 31
    • 79957759169 scopus 로고    scopus 로고
    • 2 already causes significant cytotoxicity. Consequently, longer reaction times and/or higher concentrations of the analyte were required to compensate for the slow kinetics of internalization of hypochlorite into the cells
    • 2 already causes significant cytotoxicity. Consequently, longer reaction times and/or higher concentrations of the analyte were required to compensate for the slow kinetics of internalization of hypochlorite into the cells.
  • 41
    • 77956048112 scopus 로고    scopus 로고
    • Angew. Chem. Int. Ed. 2010, 49, 6134-6138
    • (2010) Angew. Chem. Int. Ed. , vol.49 , pp. 6134-6138


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.