Identification and functional characterization of a missense mutation in resistin in two patients with severe obesity and insulin resistance

European Journal of Endocrinology

Volumn 164, Issue 6, 2011, Pages 927-936

  Beckers, Sigri ^a   De Freitas, Fenna ^a   Zegers, Doreen ^a   Verrijken, An ^b   Peeters, Armand V ^b   Peiffer, Frida ^b   Verhulst, Stijn L ^b   Massa, Guy ^c   Mertens, Ilse L ^b   Desager, Kristine N ^b   Van Gaal, Luc F ^b   Van Hul, Wim ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b ANTWERP UNIVERSITY HOSPITAL   (Belgium)

^c JESSA HOSPITAL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; CELL PROTEIN; CYSTEINE; CYTOSINE; GUANINE; MESSENGER RNA; MUTANT PROTEIN; RESISTIN; SERINE; THYMINE; COMPLEMENTARY DNA; HEMOGLOBIN A1C;

3' UNTRANSLATED REGION; ADIPOCYTE; ADOLESCENT; ADULT; ANIMAL CELL; ARTICLE; BODY MASS; CELL STRAIN 3T3; CHILD; CONTROLLED STUDY; CULTURE MEDIUM; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL DESIGN; FEMALE; GENETIC CODE; GENETIC PREDISPOSITION; GENETIC SCREENING; GENETIC TRANSFECTION; GENETIC VARIABILITY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; INSULIN RESISTANCE; LEAN BODY WEIGHT; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; MONOGENIC DISORDER; MORBID OBESITY; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SEQUENCE ANALYSIS; WESTERN BLOTTING; WILD TYPE; AGED; AMPLICON; CELL LYSATE; EXON; FUNCTIONAL GENOMICS; GENE EXPRESSION; GENETIC IDENTIFICATION; GENETIC POLYMORPHISM; HETEROZYGOTE; INTRON; PROTEIN SECRETION; REAL TIME POLYMERASE CHAIN REACTION; SCHOOL CHILD;

3' UNTRANSLATED REGIONS; 3T3-L1 CELLS; ADOLESCENT; ADULT; ANIMALS; BODY MASS INDEX; BODY WEIGHT; CHILD; DNA MUTATIONAL ANALYSIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXONS; FAMILY; FEMALE; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HETEROZYGOTE; HUMANS; INSULIN RESISTANCE; MALE; MICE; MIDDLE AGED; MUTATION, MISSENSE; OBESITY, MORBID; RESISTIN; RNA, MESSENGER; TRANSFECTION; YOUNG ADULT;

EID: 79957733711     PISSN: 08044643     EISSN: 1479683X     Source Type: Journal    
DOI: 10.1530/EJE-10-1080     Document Type: Article

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