Lipid cubic phase as a membrane mimetic for integral membrane protein enzymes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 21, 2011, Pages 8639-8644

  Li, Dianfan ^a   Caffrey, Martin ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Coupled enzyme assay; DgkA; Glycerophospholipid; PgsA; Phosphatidylglycerol phosphate synthase

Indexed keywords

DGKA ENZYME; DIACYLGLYCEROL KINASE; LIPID; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME STRUCTURE; MICHAELIS MENTEN KINETICS; PRIORITY JOURNAL;

CATALYSIS; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DIACYLGLYCEROL KINASE; ENZYMES; LIPID BILAYERS; LIPIDS; MEMBRANE PROTEINS; MEMBRANES, ARTIFICIAL; MODELS, BIOLOGICAL;

EID: 79957730165     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1101815108     Document Type: Article

References (37)

1. Rosenbaum DM, et al. (2007) GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function. Science 318:1266-1273. (Pubitemid 350172885)
2. Cherezov V, et al. (2007) High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor. Science 318:1258-1265. (Pubitemid 350172884)
3. Jaakola VP, et al. (2008) The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist. Science 322:1211-1217.
4. Wu B, et al. (2010) Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. Science 330:1066-1071.
5. Chien EY, et al. (2010) Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist. Science 330:1091-1095.
6. Rasmussen SG, et al. (2011) Structure of a nanobody-stabilized active state of the beta (2) adrenoceptor. Nature 469:175-180.
7. Rosenbaum DM, et al. (2011) Structure and function of an irreversible agonist-beta(2) adrenoceptor complex. Nature 469:236-240.
8. Caffrey M, Cherezov V (2009) Crystallizing membrane proteins using lipidic mesophases. Nat Protoc 4:706-731.
9. Caffrey M (2009) Crystallizing membrane proteins for structure determination: Use of lipidic mesophases. Annu Rev Biophys 38:29-51.
10. Landau EM, Rosenbusch JP (1996) Lipidic cubic phases: A novel concept for the crystallization of membrane proteins. Proc Natl Acad Sci USA 93:14532-14535. (Pubitemid 26419001)
11. Cherezov V, Clogston J, Papiz MZ, Caffrey M (2006) Room to move: Crystallizing membrane proteins in swollen lipidic mesophases. J Mol Biol 357:1605-1618.
12. Katona G, Andreasson U, Landau EM, Andreasson LE, Neutze R (2003) Lipidic cubic phase crystal structure of the photosynthetic reaction centre from Rhodobacter sphaeroides at 2.35 A resolution. J Mol Biol 331:681-692. (Pubitemid 36937154)
13. Cherezov V, et al. (2006) In meso structure of the cobalamin transporter, BtuB, at 1.95 A resolution. J Mol Biol 364:716-734.
14. Hofer N, Aragao D, Caffrey M (2010) Crystallizing transmembrane peptides in lipidic mesophases. Biophys J 99:L23-25.
15. Cherezov V, et al. (2008) In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin. Proteins 71:24-34.
16. Raetz CR, Newman KF (1979) Diglyceride kinase mutants of Escherichia coli: Inner membrane association of 1,2-diglyceride and its relation to synthesis of membrane-derived oligosaccharides. J Bacteriol 137:860-868. (Pubitemid 9122320)
17. Van Horn WD, et al. (2009) Solution nuclear magnetic resonance structure of membrane-integral diacylglycerol kinase. Science 324:1726-1729.
18. Lorch M, et al. (2005) How to prepare membrane proteins for solid-state NMR: A case study on the alpha-helical integral membrane protein diacylglycerol kinase from E. coli. Chembiochem 6:1693-1700. (Pubitemid 41296978)
19. Tanzer ML, Gilvarg C (1959) Creatine and creatine kinase measurement. J Biol Chem 234:3201-3204.
20. Badola P, Sanders CR (1997) Escherichia coli diacylglycerol kinase is an evolutionarily optimized membrane enzyme and catalyzes direct phosphoryl transfer. J Biol Chem 272:24176-24182. (Pubitemid 27418616)
21. Czerski L, Sanders CR (2000) Functionality of a membrane protein in bicelles. Anal Biochem 284:327-333.
22. Bohnenberger E, Sandermann H, Jr (1982) Diglyceride kinase from Escherichia coli. Modulation of enzyme activity by glycosphingolipids. Biochim Biophys Acta 685:44-50.
23. Schneider EG, Kennedy EP (1973) Phosphorylation of ceramide by diglyceride kinase preparations from Escherichia coli. J Biol Chem 248:3739-3741.
24. Schneider EG, Kennedy EP (1976) Partial purification and properties of diglyceride kinase from Escherichia coli. Biochim Biophys Acta 441:201-212.
25. Walsh JP, Fahrner L, Bell RM(1990) sn-1,2-diacylglycerol kinase of Escherichia coli. Diacylglycerol analogues define specificity and mechanism. J Biol Chem 265:4374-4381.
26. Liu W, Caffrey M (2005) Gramicidin structure and disposition in highly curved membranes. J Struct Biol 150:23-40. (Pubitemid 40395299)
27. Walsh JP, Bell RM(1986) sn-1,2-Diacylglycerol kinase of Escherichia coli.Mixed micellar analysis of the phospholipid cofactor requirement and divalent cation dependence. J Biol Chem 261:6239-6247. (Pubitemid 17204128)
28. Clogston J, Rathman J, Tomasko D, Walker H, Caffrey M (2000) Phase behavior of a monoacylglycerol: (myverol 18-99 K)/water system. Chem Phys Lipids 107:191-220.
29. Hochkoeppler A, et al. (1995) Photochemistry of a photosynthetic reaction center immobilized in lipidic cubic phases. Biotechnol Bioeng 46:93-98.
30. Qiu H, Caffrey M (2000) The phase diagram of the monoolein/water system: Metastability and equilibrium aspects. Biomaterials 21:223-234.
31. Pilot JD, East JM, Lee AG (2001) Effects of bilayer thickness on the activity of diacylglycerol kinase of Escherichia coli. Biochemistry 40:8188-8195. (Pubitemid 32661878)
32. Zhou Y, Bowie JU (2000) Building a thermostable membrane protein. J Biol Chem 275:6975-6979. (Pubitemid 30146241)
33. Misquitta Y, Caffrey M (2003) Detergents destabilize the cubic phase of monoolein: Implications for membrane protein crystallization. Biophys J 85:3084-3096. (Pubitemid 37345796)
34. Ai X, Caffrey M (2000) Membrane protein crystallization in lipidic mesophases: Detergent effects. Biophys J 79:394-405. (Pubitemid 30436755)
35. Dowhan W (1992) Phosphatidylglycerophosphate synthase from Escherichia coli. Methods Enzymol 209:313-321.
36. Sanders CR, et al. (1996) Escherichia coli diacylglycerol kinase is an alpha-helical polytopic membrane protein and can spontaneously insert into preformed lipid vesicles. Biochemistry 35:8610-8618.
37. Cheng A, Hummel B, Qiu H, Caffrey M (1998) A simple mechanical mixer for small viscous lipid-containing samples. Chem Phys Lipids 95:11-21. (Pubitemid 29034715)