-
1
-
-
0021342348
-
Rapid enumeration of S-phase cells by means of monoclonal antibodies
-
Raza A, Preisler HD, Mayers GL and Bankert R: Rapid enumeration of S-phase cells by means of monoclonal antibodies. N Engl J Med 310: 991, 1984. (Pubitemid 14173247)
-
(1984)
New England Journal of Medicine
, vol.310
, Issue.15
, pp. 991
-
-
Raza, A.1
Preisler, H.D.2
Mayers, G.L.3
Bankert, R.4
-
2
-
-
0023237692
-
Differences in cell cycle characteristics among patients with acute nonlymphocytic leukemia
-
Raza A, Maheshwari Y and Preisler HD: Differences in cell cycle characteristics among patients with acute nonlymphocytic leukemia. Blood 69: 1647-1653, 1987. (Pubitemid 17091620)
-
(1987)
Blood
, vol.69
, Issue.6
, pp. 1647-1653
-
-
Raza, A.1
Maheshwari, Y.2
Preisler, H.D.3
-
3
-
-
0027285546
-
Expression of the proliferating cell nuclear antigen in bone marrow cells from patients with myelodysplastic syndromes and aplastic anemia
-
DOI 10.1016/0046-8177(93)90082-R
-
Kitagawa M, Kamiyama R and Kasuga T: Expression of the proliferating cell nuclear antigen in bone marrow cells from patients with myelodysplastic syndromes and aplastic anemia. Hum Pathol 24: 359-363, 1992. (Pubitemid 23127250)
-
(1993)
Human Pathology
, vol.24
, Issue.4
, pp. 359-363
-
-
Kitagawa, M.1
Kamiyama, R.2
Kasuga, T.3
-
4
-
-
0029020851
-
Apoptosis in bone marrow biopsy samples involving stromal and hematopoietic cells in 50 patients with myelodysplastic syndromes
-
Raza A, Gezer S, Mundle S, et al: Apoptosis in bone marrow biopsy samples involving stromal and hematopoietic cells in 50 patients with myelodysplastic syndromes. Blood 86: 268-276, 1995.
-
(1995)
Blood
, vol.86
, pp. 268-276
-
-
Raza, A.1
Gezer, S.2
Mundle, S.3
-
5
-
-
0031464758
-
Overexpression of tumor necrosis factor (TNF)-α and interferon (IFN)-γ by bone marrow cells from patients with myelodysplastic syndromes
-
Kitagawa M, Saito I, Kuwata T, Yoshida S, Yamaguchi S, Takahashi M, Tanizawa T, Kamiyama R and Hirokawa K: Overexpression of tumor necrosis factor (TNF)-α and interferon (IFN)-γ by bone marrow cells from patients with myelodysplastic syndromes. Leukemia 11: 2049-2054, 1997. (Pubitemid 28043688)
-
(1997)
Leukemia
, vol.11
, Issue.12
, pp. 2049-2054
-
-
Kitagawa, M.1
Saito, I.2
Kuwata, T.3
Yoshida, S.4
Yamaguchi, S.5
Takahashi, M.6
Tanizawa, T.7
Kamiyama, R.8
Hirokawa, K.9
-
6
-
-
0031979845
-
Localization of Fas and Fas ligand in bone marrow cells demonstrating myelodysplasia
-
DOI 10.1038/sj.leu.2400980
-
Kitagawa M, Yamaguchi S, Takahashi M, Tanizawa T, Hirokawa K and Kamiyama R: Localization of Fas and Fas ligand in bone marrow cells demonstrating myelodysplasia. Leukemia 12: 486-492, 1998. (Pubitemid 28197571)
-
(1998)
Leukemia
, vol.12
, Issue.4
, pp. 486-492
-
-
Kitagawa, M.1
Yamaguchi, S.2
Takahashi, M.3
Tanizawa, T.4
Hirokawa, K.5
Kamiyama, R.6
-
7
-
-
0033049595
-
Expression of inducible nitric oxide synthase (NOS) in bone marrow cells of myelodysplastic syndromes
-
Kitagawa M, Takahashi M, Yamaguchi S, Inoue M, Ogawa S, Hirokawa K and Kamiyama R: Expression of inducible nitric oxide synthase (NOS) in bone marrow cells of myelodysplastic syndromes. Leukemia 13: 699-703, 1999. (Pubitemid 29243619)
-
(1999)
Leukemia
, vol.13
, Issue.5
, pp. 699-703
-
-
Kitagawa, M.1
Takahashi, M.2
Yamaguchi, S.3
Inoue, M.4
Ogawa, S.5
Hirokawa, K.6
Kamiyama, R.7
-
8
-
-
0030293115
-
The myelodysplastic syndromes in 1996: Complex stem cell disorders confounded by dual actions of cytokines
-
Raza A, Gregory SA and Preisler HD: The myelodysplastic syndromes in 1996: complex stem cell disorders confounded by dual actions of cytokines. Leuk Res 20: 881-890, 1996.
-
(1996)
Leuk Res
, vol.20
, pp. 881-890
-
-
Raza, A.1
Gregory, S.A.2
Preisler, H.D.3
-
9
-
-
17144441932
-
Evidence for involvement of tumor necrosis factor-α in apoptotic death of bone marrow cells in myelodysplastic syndromes
-
DOI 10.1002/(SICI)1096-8652(199901)60:1<36::AID-AJH7>3.0.CO;2-#
-
Mundle SD, Ali A, Cartlidge JD, Reza S, Alvi S, Showel MM, Mativi BY, Shetty VT, Venugopal P, Gregory SA and Raza A: Evidence for involvement of tumor necrosis factor-α in apoptotic death of bone marrow cells in myelodysplastic syndromes. Am J Hematol 60: 36-47, 1999. (Pubitemid 28565850)
-
(1999)
American Journal of Hematology
, vol.60
, Issue.1
, pp. 36-47
-
-
Mundle, S.D.1
Ali, A.2
Cartlidge, J.D.3
Reza, S.4
Alvi, S.5
Showel, M.M.6
Mativi, B.Y.7
Shetty, V.T.8
Venugopal, P.9
Gregory, S.A.10
Raza, A.11
-
10
-
-
0036493359
-
In vitro proliferation and differentiation of erythroid progenitors from patients with myelodysplastic syndromes: Evidence for Fas-dependent apoptosis
-
Claessens YE, Bouscary D, Dupont JM, Picard F, Melle J, Gisselbrecht S, Lacombe C, Dreyfus F, Mayeux P and Fontenay-Roupie M: In vitro proliferation and differentiation of erythroid progenitors from patients with myelodysplastic syndromes: evidence for Fas-dependent apoptosis. Blood 99: 1594-1601, 2002.
-
(2002)
Blood
, vol.99
, pp. 1594-1601
-
-
Claessens, Y.E.1
Bouscary, D.2
Dupont, J.M.3
Picard, F.4
Melle, J.5
Gisselbrecht, S.6
Lacombe, C.7
Dreyfus, F.8
Mayeux, P.9
Fontenay-Roupie, M.10
-
11
-
-
13244290233
-
Evidence for a role of TNF-related apoptosis-inducing ligand (TRAIL) in the anemia of myelodysplastic syndromes
-
Campioni D, Secchiero P, Corallini F, Melloni E, Capitani S, Lanza F and Zauli G: Evidence for a role of TNF-related apoptosis-inducing ligand (TRAIL) in the anemia of myelodysplastic syndromes. Am J Pathol 166: 557-563, 2005. (Pubitemid 40189051)
-
(2005)
American Journal of Pathology
, vol.166
, Issue.2
, pp. 557-563
-
-
Campioni, D.1
Secchiero, P.2
Corallini, F.3
Melloni, E.4
Capitani, S.5
Lanza, F.6
Zauli, G.7
-
12
-
-
0037411227
-
Expression of TNF receptors and related signaling molecules in the bone marrow from patients with myelodysplastic syndromes
-
DOI 10.1016/S0145-2126(02)00095-4, PII S0145212602000954
-
Sawanobori M, Yamaguchi S, Hasegawa M, Inoue M, Suzuki K, Kamiyama R, Hirokawa K and Kitagawa M: Expression of TNF receptors and related signaling molecules in the bone marrow from patients with myelodysplastic syndromes. Leukemia Res 27: 583-591, 2003. (Pubitemid 36398093)
-
(2003)
Leukemia Research
, vol.27
, Issue.7
, pp. 583-591
-
-
Sawanobori, M.1
Yamaguchi, S.2
Hasegawa, M.3
Inoue, M.4
Suzuki, K.5
Kamiyama, R.6
Hirokawa, K.7
Kitagawa, M.8
-
13
-
-
84880968072
-
The biology of myelodysplastic syndromes: Unity despite heterogeneity
-
Raza A, Cruz R, Latif T, Mukherjee S and Galili N: The biology of myelodysplastic syndromes: unity despite heterogeneity. Hemato Rep 2: 28-31, 2010.
-
(2010)
Hemato Rep
, vol.2
, pp. 28-31
-
-
Raza, A.1
Cruz, R.2
Latif, T.3
Mukherjee, S.4
Galili, N.5
-
14
-
-
0030822192
-
Apoptosis resistance of blood cells from patients with paroxysmal nocturnal hemoglobinuria, aplastic anemia, and myelodysplastic syndrome
-
Horikawa K, Nakakuma H, Kawaguchi T, Iwamoto N, Nagakura S, Kagimoto T and Takatsuki K: Apoptosis resistance of blood cells from patients with paroxysmal nocturnal hemoglobinuria, aplastic anemia, and myelodysplastic syndrome. Blood 90: 2716-2722, 1997. (Pubitemid 27413481)
-
(1997)
Blood
, vol.90
, Issue.7
, pp. 2716-2722
-
-
Horikawa, K.1
Nakakuma, H.2
Kawaguchi, T.3
Iwamoto, N.4
Nagakura, S.5
Kagimoto, T.6
Takatsuki, K.7
-
15
-
-
0035283119
-
Vascular endothelial cell growth factor is an autocrine promoter of abnormal localized immature myeloid precursors and leukemia progenitor formation in myelodysplastic syndromes
-
DOI 10.1182/blood.V97.5.1427
-
Bellamy WT, Richter L, Sirjani D, Roxas C, Glinsmann Gibson B, Frutiger Y, Grogan TM and List AF: Vascular endothelial cell growth factor is an autocrine promoter of abnormal localized immature myeloid precursors and leukaemia progenitor formation in myelodysplastic syndromes. Blood 97: 1427-1434, 2001. (Pubitemid 32183769)
-
(2001)
Blood
, vol.97
, Issue.5
, pp. 1427-1434
-
-
Bellamy, W.T.1
Richter, L.2
Sirjani, D.3
Roxas, C.4
Glinsmann-Gibson, B.5
Frutiger, Y.6
Grogan, T.M.7
List, A.F.8
-
16
-
-
0036062374
-
Clinical relevance of vascular endothelial growth factor receptors 1 and 2 in acute myeloid leukaemia and myelodysplastic syndrome
-
DOI 10.1046/j.1365-2141.2002.03551.x
-
Verstovsek S, Estey E, Manshouri T, Giles FJ, Cortes J, Beran M, Rogers A, Keating M, Kantarjian H and Albitar M: Clinical relevance of vascular endothelial growth factor receptors 1 and 2 in acute myeloid leukaemia and myelodysplastic syndromes. Br J Haematol 118: 151-156, 2002. (Pubitemid 34779531)
-
(2002)
British Journal of Haematology
, vol.118
, Issue.1
, pp. 151-156
-
-
Verstovsek, S.1
Estey, E.2
Manshouri, T.3
Giles, F.J.4
Cortes, J.5
Beran, M.6
Rogers, A.7
Keating, M.8
Kantarjian, H.9
Albitar, M.10
-
17
-
-
34047224675
-
Regulation of angiogenesis in the bone marrow of myelodysplastic syndromes transforming to overt leukaemia
-
DOI 10.1111/j.1365-2141.2007.06539.x
-
Keith T, Araki Y, Ohyagi M, Hasegawa M, Yamamoto K, Kurata M, Nakagawa Y, Suzuki K and Kitagawa M: Regulation of angiogenesis in the bone marrow of myelodysplastic syndromes transforming to overt leukaemia. Br J Haematol 137: 206-215, 2007. (Pubitemid 46537630)
-
(2007)
British Journal of Haematology
, vol.137
, Issue.3
, pp. 206-215
-
-
Keith, T.1
Araki, Y.2
Ohyagi, M.3
Hasegawa, M.4
Yamamoto, K.5
Kurata, M.6
Nakagawa, Y.7
Suzuki, K.8
Kitagawa, M.9
-
18
-
-
33845992842
-
Reduced expression of inducible gelatinase B/matrix metalloproteinase-9 in monocytes from patients with myelodysplastic syndrome: Correlation of inducible levels with the percentage of cytogenetically marked cells and with marrow cellularity
-
DOI 10.1182/blood-2006-05-020289
-
Iwata M, Pillai M, Ramakrishnan A, Hackman RC, Deeg HJ, Opdenakker G and Torok-Storb B: Reduced expression of inducible gelatinase B/matrix metalloproteinase-9 in monocytes from patients with myelodysplastic syndrome: correlation of inducible levels with the percentage of cytogenetically marked cells and with marrow cellularity. Blood 109: 85-92, 2007. (Pubitemid 46053047)
-
(2007)
Blood
, vol.109
, Issue.1
, pp. 85-92
-
-
Iwata, M.1
Pillai, M.2
Ramakrishnan, A.3
Hackman, R.C.4
Deeg, H.J.5
Opdenakker, G.6
Torok-Storb, B.7
-
19
-
-
39149091719
-
Biological and clinical relevance of matrix metalloproteinases 2 and 9 in acute myeloid leukaemias and myelodysplastic syndromes
-
DOI 10.1111/j.1600-0609.2007.01012.x
-
Travaglino E, Benatti C, Malcovati L, Della Porta MG, Gallì A, Sonetti E, Rosti V, Cazzola M and Invernizzi R: Biological and clinical relevance of matrix metalloproteinases 2 and 9 in acute myeloid leukemias and myelodysplastic syndromes. Eur J Haematol 80: 216-226, 2008. (Pubitemid 351253461)
-
(2008)
European Journal of Haematology
, vol.80
, Issue.3
, pp. 216-226
-
-
Travaglino, E.1
Benatti, C.2
Malcovati, L.3
Porta, M.G.D.4
Galli, A.5
Bonetti, E.6
Rosti, V.7
Cazzola, M.8
Invernizzi, R.9
-
20
-
-
77950862042
-
Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
-
Raaijmakers MH, Mukherjee S, Guo S, et al: Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia. Nature 464: 852-857, 2010.
-
(2010)
Nature
, vol.464
, pp. 852-857
-
-
Raaijmakers, M.H.1
Mukherjee, S.2
Guo, S.3
-
21
-
-
0030897009
-
International scoring system for evaluating prognosis in myelodysplastic syndromes
-
Greenberg P, Cox C, LeBeau MM, et al: International Scoring System for evaluating prognosis in myelodysplastic syndromes. Blood 89: 2079-2088, 1997. (Pubitemid 27132124)
-
(1997)
Blood
, vol.89
, Issue.6
, pp. 2079-2088
-
-
Greenberg, P.1
Cox, C.2
LeBeau, M.M.3
Fenaux, P.4
Morel, P.5
Sanz, G.6
Sanz, M.7
Vallespi, T.8
Hamblin, T.9
Oscier, D.10
Ohyashiki, K.11
Toyama, K.12
Aul, C.13
Mufti, G.14
Bennett, J.15
-
23
-
-
0037114753
-
Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: Results from cancer and leukemia group B (CALGB 8461)
-
DOI 10.1182/blood-2002-03-0772
-
Byrd JC, Mrózek K, Dodge RK, et al: Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukaemia: results from Cancer and Leukemia Study Group B (CALGB 8461). Blood 100: 4325-4336, 2002. (Pubitemid 35429670)
-
(2002)
Blood
, vol.100
, Issue.13
, pp. 4325-4336
-
-
Byrd, J.C.1
Mrozek, K.2
Dodge, R.K.3
Carroll, A.J.4
Edwards, C.G.5
Arthur, D.C.6
Pettenati, M.J.7
Patil, S.R.8
Rao, K.W.9
Watson, M.S.10
Koduru, P.R.K.11
Moore, J.O.12
Stone, R.M.13
Mayer, R.J.14
Feldman, E.J.15
Davey, F.R.16
Schiffer, C.A.17
Larson, R.A.18
Bloomfield, C.D.19
-
24
-
-
23744513172
-
Incidence and prognostic significance of karyotype abnormalities in de novo primary myelodysplastic syndromes: A study on 331 patients from a single institution
-
DOI 10.1038/sj.leu.2403806
-
Bernasconi P, Klersy C, Boni M, Cavigliano PM, Calatroni S, Giardini I, Rocca B, Zappatore R, Caresana M, Lazzarino M and Bernasconi C: Incidence and prognostic significance of karyotype abnormalities in de novo primary myelodysplastic syndromes: a study on 331 patients from a single institution. Leukemia 19: 1424-1431, 2005. (Pubitemid 41136337)
-
(2005)
Leukemia
, vol.19
, Issue.8
, pp. 1424-1431
-
-
Bernasconi, P.1
Klersy, C.2
Boni, M.3
Cavigliano, P.M.4
Calatroni, S.5
Giardini, I.6
Rocca, B.7
Zappatore, R.8
Caresana, M.9
Quarna, J.10
Lazzarino, M.11
Bernasconi, C.12
-
25
-
-
34047220891
-
World Health Organization classification in combination with cytogenetic markers improves the prognostic stratification of patients with de novo primary myelodysplastic syndromes
-
DOI 10.1111/j.1365-2141.2007.06537.x
-
Bernasconi P, Klersy C, Boni M, Cavigliano PM, Calatroni S, Giardini I, Rocca B, Zappatore R, Caresana M, Dambruoso I, Lazzarino M and Bernasconi C: World Health Organization classification in combination with cytogenetic markers improves the prognostic stratification of patients with de novo primary myelodysplastic syndromes. Br J Haematol 137: 193-205, 2006. (Pubitemid 46537628)
-
(2007)
British Journal of Haematology
, vol.137
, Issue.3
, pp. 193-205
-
-
Bernasconi, P.1
Klersy, C.2
Boni, M.3
Cavigliano, P.M.4
Calatroni, S.5
Giardini, I.6
Rocca, B.7
Zappatore, R.8
Caresana, M.9
Dambruoso, I.10
Lazzarino, M.11
Bernasconi, C.12
-
26
-
-
39649094569
-
New insights into the prognostic impact of the karyotype in MDS and correlation with subtypes: Evidence from a core dataset of 2124 patients
-
DOI 10.1182/blood-2007-03-082404
-
Haase D, Germing U, Schanz J, et al: New insights into the prognostic impact of karyotype in MDS and correlations with subtypes: evidence from a core dataset of 2124 patients. Blood 110: 4385-4395, 2007. (Pubitemid 351377805)
-
(2007)
Blood
, vol.110
, Issue.13
, pp. 4385-4395
-
-
Haase, D.1
Germing, U.2
Schanz, J.3
Pfeilstocker, M.4
Nosslinger, T.5
Hildebrandt, B.6
Kundgen, A.7
Lubbert, M.8
Kunzmann, R.9
Giagounidis, A.A.N.10
Aul, C.11
Trumper, L.12
Krieger, O.13
Stauder, R.14
Muller, T.H.15
Wimazal, F.16
Valent, P.17
Fonatsch, C.18
Steidl, C.19
-
27
-
-
0016348695
-
Distinct haematological disorder with deletion of long arm of no. 5 chromosome
-
Van den Berghe H, Cassiman JJ, David G, Fryns JP, Michaux JL and Sokal G: Distinct haematological disorder with deletion of long arm of no. 5 chromosome. Nature 251: 437-438, 1974.
-
(1974)
Nature
, vol.251
, pp. 437-438
-
-
Van Den Berghe, H.1
Cassiman, J.J.2
David, G.3
Fryns, J.P.4
Michaux, J.L.5
Sokal, G.6
-
28
-
-
10744229499
-
Clinical, morphological, cytogenetic, and prognostic features of patients with myelodysplastic syndromes and del(5q) including band q31
-
DOI 10.1038/sj.leu.2403189
-
Giagounidis AA, Germing U, Haase S, Hildebrandt B, Schlegelberger B, Schoch C, Wilkens L, Heinsch M, Willems H, Aivado M and Aul C: Clinical, morphological, cytogenetic, and prognostic features of patients with myelodysplastic syndromes and del(5q) including band q31. Leukemia 18: 113-119, 2004. (Pubitemid 38159446)
-
(2004)
Leukemia
, vol.18
, Issue.1
, pp. 113-119
-
-
Giagounidis, A.A.N.1
Germing, U.2
Haase, S.3
Hildebrandt, B.4
Schlegelberger, B.5
Schoch, C.6
Wilkens, L.7
Heinsch, M.8
Willems, H.9
Aivado, M.10
Aul, C.11
-
29
-
-
0034665776
-
Isolation and characterization of hematopoietic progenitor/stem cells in 5q-deleted myelodysplastic syndromes: Evidence for involvement at the hematopoietic stem cell level
-
Nilsson L, Astrand-Grundstrom I, Arvidsson I, Jacobsson B, Hellstrom-Lindberg E, Hast R and Jacobsen SE: Isolation and characterization of hematopoietic progenitor/stem cells in 5q-deleted myelodysplastic syndromes: evidence for involvement at the hematopoietic stem cell level. Blood 96: 2012-2021, 2000.
-
(2000)
Blood
, vol.96
, pp. 2012-2021
-
-
Nilsson, L.1
Astrand-Grundstrom, I.2
Arvidsson, I.3
Jacobsson, B.4
Hellstrom-Lindberg, E.5
Hast, R.6
Jacobsen, S.E.7
-
30
-
-
38349088899
-
Identification of RPS14 as a 5q- syndrome gene by RNA interference screen
-
Ebert BL, Pretz J, Bosco J, Chang CY, Tamayo P, Galili N, Raza A, Root DE, Attar E, Ellis SR and Golub TR: Identification of RPS14 as a 5q- syndrome gene by RNA interference screen. Nature 451: 335-339, 2008.
-
(2008)
Nature
, vol.451
, pp. 335-339
-
-
Ebert, B.L.1
Pretz, J.2
Bosco, J.3
Chang, C.Y.4
Tamayo, P.5
Galili, N.6
Raza, A.7
Root, D.E.8
Attar, E.9
Ellis, S.R.10
Golub, T.R.11
-
31
-
-
0032907438
-
The gene encoding ribosomal protein S19 is mutated in Diamond-Blackfan anaemia
-
DOI 10.1038/5951
-
Draptchinskaia N, Gustavsson P, Andersson B, et al: The gene encoding ribosomal protein S19 is mutated in Diamond-Blackfan anaemia. Nature Gen 21: 169-175, 1999. (Pubitemid 29070361)
-
(1999)
Nature Genetics
, vol.21
, Issue.2
, pp. 169-175
-
-
Draptchinskaia, N.1
Gustavsson, P.2
Andersson, B.3
Pettersson, M.4
Willig, T.-N.5
Dianzani, I.6
Ball, S.7
Tchernia, G.8
Klar, J.9
Matsson, H.10
Tentler, D.11
Mohandas, N.12
Carlsson, B.13
Dahl, N.14
-
32
-
-
19344366193
-
Many ribosomal protein genes are cancer genes in zebrafish
-
Amsterdam A, Sadler KC, Lai K, Farrington S, Bronson R, Lees JA and Hopkins N: Many ribosomal protein genes are cancer genes in zebrafish. PLoS Biol 2: E139, 2004.
-
(2004)
PLoS Biol
, vol.2
-
-
Amsterdam, A.1
Sadler, K.C.2
Lai, K.3
Farrington, S.4
Bronson, R.5
Lees, J.A.6
Hopkins, N.7
-
33
-
-
73849121794
-
Identification of miR-145 and miR-146a as mediators of the 5q-syndrome phenotype
-
Starczynowski DT, Kuchenbauer F, Argiropoulos B, et al: Identification of miR-145 and miR-146a as mediators of the 5q-syndrome phenotype. Nature Med 16: 49-58, 2010.
-
(2010)
Nature Med
, vol.16
, pp. 49-58
-
-
Starczynowski, D.T.1
Kuchenbauer, F.2
Argiropoulos, B.3
-
34
-
-
73849128091
-
A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- Syndrome
-
Barlow JL, Drynan LF, Hewett DR, et al: A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome. Nature Med 16: 59-66, 2010.
-
(2010)
Nature Med
, vol.16
, pp. 59-66
-
-
Barlow, J.L.1
Drynan, L.F.2
Hewett, D.R.3
-
35
-
-
77952579886
-
New clues to the molecular pathogenesis of myelodysplastic syndromes
-
Jädersten M and Hellström-Lindberg E: New clues to the molecular pathogenesis of myelodysplastic syndromes. Exp Cell Res 316: 1390-1396, 2010.
-
(2010)
Exp Cell Res
, vol.316
, pp. 1390-1396
-
-
Jädersten, M.1
Hellström-Lindberg, E.2
-
36
-
-
34547474047
-
Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q- Syndrome patients
-
DOI 10.1073/pnas.0610477104
-
Pellagatti A, Jadersten M, Forsblom AM, et al: Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q- syndromepatients. Proc Natl Acad Sci USA 104: 11406-11411, 2007. (Pubitemid 47175153)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.27
, pp. 11406-11411
-
-
Pellagatti, A.1
Jadersten, M.2
Forsblom, A.-M.3
Cattan, H.4
Christensson, B.5
Emanuelsson, E.K.6
Merup, M.7
Nilsson, L.8
Samuelsson, J.9
Sander, B.10
Wainscoat, J.S.11
Boultwood, J.12
Hellstrom-Lindberg, E.13
-
37
-
-
10644250277
-
SPARC and tumor growth: Where the seed meets the soil?
-
Framson PE and Sage EH: SPARC and tumor growth: where the seed meets the soil? J Cell Biochem 92: 679-690, 2004.
-
(2004)
J Cell Biochem
, vol.92
, pp. 679-690
-
-
Framson, P.E.1
Sage, E.H.2
-
38
-
-
17844383458
-
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
-
DOI 10.1038/nature03546
-
James C, Ugo V, Le Couedic JP, et al: A unique clonal JAK2 mutation leading to constitutive signaling causes polycythaemia vera. Nature 434: 1144-1148, 2005. (Pubitemid 40663494)
-
(2005)
Nature
, vol.434
, Issue.7037
, pp. 1144-1148
-
-
James, C.1
Ugo, V.2
Le, C.J.-P.3
Staerk, J.4
Delhommeau, F.5
Lacout, C.6
Garcon, L.7
Raslova, H.8
Berger, R.9
Bennaceur-Griscelli, A.10
Villeval, J.L.11
Constantinescu, S.N.12
Casadevall, N.13
Vainchenker, W.14
-
39
-
-
33746437130
-
MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia
-
Pikman Y, Lee BH, Mercher T, et al: MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia. PLoS Med 3: e270, 2006.
-
(2006)
PLoS Med
, vol.3
-
-
Pikman, Y.1
Lee, B.H.2
Mercher, T.3
-
40
-
-
33846660947
-
JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis
-
DOI 10.1056/NEJMoa065202
-
Scott LM, Tong W, Levine RL, et al: JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis. N Engl J Med 356: 459-468, 2007. (Pubitemid 46193073)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.5
, pp. 459-468
-
-
Scott, L.M.1
Tong, W.2
Levine, R.L.3
Scott, M.A.4
Beer, P.A.5
Stratton, M.R.6
Futreal, P.A.7
Erber, W.N.8
McMullin, M.F.9
Harrison, C.N.10
Warren, A.J.11
Gilliland, D.G.12
Lodish, H.F.13
Green, A.R.14
-
41
-
-
33749325187
-
Refractory anemia with ringed sideroblasts associated with marked thrombocytosis (RARS-T), another myeloproliferative condition characterized by JAK2 V617F mutation
-
DOI 10.1182/blood-2006-02-005751
-
Szpurka H, Tiu R, Murugesan G, Aboudola S, His ED, Theil KS, Sekeres MA and Maciejewski JP: Refractory anemia with ringed sideroblasts associated with marked thrombocytosis (RARS-T), another myeloproliferative condition characterized by JAK2 V617F mutation. Blood 108: 2173-2181, 2006. (Pubitemid 44497497)
-
(2006)
Blood
, vol.108
, Issue.7
, pp. 2173-2181
-
-
Szpurka, H.1
Tiu, R.2
Murugesan, G.3
Aboudola, S.4
Hsi, E.D.5
Theil, K.S.6
Sekeres, M.A.7
Maciejewski, J.P.8
-
42
-
-
33745213401
-
The JAK2 V617F mutation identifies a subgroup of MDS patients with isolated deletion 5q and a proliferative bone marrow [14]
-
DOI 10.1038/sj.leu.2404215, PII 2404215
-
Ingram W, Lea NC, Cervera J, et al: The JAK2 V617F mutation identifies a subgroup of MDS patients with isolated deletion 5q and a proliferative bone marrow. Leukemia 20: 1319-1321, 2006. (Pubitemid 43905846)
-
(2006)
Leukemia
, vol.20
, Issue.7
, pp. 1319-1321
-
-
Ingram, W.1
Lea, N.C.2
Cervera, J.3
Germing, U.4
Fenaux, P.5
Cassinat, B.6
Kiladjian, J.J.7
Varkonyi, J.8
Antunovic, P.9
Westwood, N.B.10
Arno, M.J.11
Mohamedali, A.12
Gaken, J.13
Kontou, T.14
Czepulkowski, B.H.15
Twine, N.A.16
Tamaska, J.17
Csomer, J.18
Benedek, S.19
Gattermann, N.20
Zipperer, E.21
Giagounidis, A.22
Garcia-Casado, Z.23
Sanz, G.24
Mufti, G.J.25
more..
-
43
-
-
67651065502
-
Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies
-
Abdel-Wahab O, Mullally A, Hedvat C, et al: Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies. Blood 114: 144-147, 2009.
-
(2009)
Blood
, vol.114
, pp. 144-147
-
-
Abdel-Wahab, O.1
Mullally, A.2
Hedvat, C.3
-
44
-
-
66249137734
-
Mutation in TET2 in myeloid cancers
-
Delhommeau F, Dupont, S, della Valle V, et al: Mutation in TET2 in myeloid cancers. N Engl J Med 360: 2289-2301, 2009.
-
(2009)
N Engl J Med
, vol.360
, pp. 2289-2301
-
-
Delhommeau, F.1
Dupont, S.2
Della Valle, V.3
-
45
-
-
67650588639
-
Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms
-
Jankowska AM, Szpurka H, Tiu RV, Makishima H, Afable M, Huh J, O'Keefe CL, Ganetzky R, McDevitt MA and Maciejewski JP: Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms. Blood 113: 6403-6410, 2009.
-
(2009)
Blood
, vol.113
, pp. 6403-6410
-
-
Jankowska, A.M.1
Szpurka, H.2
Tiu, R.V.3
Makishima, H.4
Afable, M.5
Huh, J.6
O'Keefe, C.L.7
Ganetzky, R.8
McDevitt, M.A.9
Maciejewski, J.P.10
-
46
-
-
67649876132
-
Acquired mutations in TET2 are common in myelodysplastic syndromes
-
Langemeijer SM, Kuiper RP, Berends M, et al: Acquired mutations in TET2 are common in myelodysplastic syndromes. Nature Genet 41: 838-842, 2009.
-
(2009)
Nature Genet
, vol.41
, pp. 838-842
-
-
Langemeijer, S.M.1
Kuiper, R.P.2
Berends, M.3
-
47
-
-
69849110150
-
Novel TET2 mutations associated with UPD4q24 in myelodysplastic syndrome
-
Mohamedali AM, Smith AE, Gaken J, Lea NC, Mian SA, Westwood NB, Strupp C, Gattermann N, Germing U and Mufti GJ: Novel TET2 mutations associated with UPD4q24 in myelodysplastic syndrome. J Clin Oncol 27: 4002-4006, 2009.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4002-4006
-
-
Mohamedali, A.M.1
Smith, A.E.2
Gaken, J.3
Lea, N.C.4
Mian, S.A.5
Westwood, N.B.6
Strupp, C.7
Gattermann, N.8
Germing, U.9
Mufti, G.J.10
-
48
-
-
70350438115
-
TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDSs)
-
Kosmider O, Gelsi-Boyer V, Cheok M, et al: TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDSs). Blood 114: 3285-3291, 2009.
-
(2009)
Blood
, vol.114
, pp. 3285-3291
-
-
Kosmider, O.1
Gelsi-Boyer, V.2
Cheok, M.3
-
49
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani M, Koh KP, Shen Y, Pastor WA, Bandukwala H, Brudno Y, Agarwal S, Iyer LM, Liu DR, Aravind L and Rao A: Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324: 930-935, 2009.
-
(2009)
Science
, vol.324
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
Pastor, W.A.4
Bandukwala, H.5
Brudno, Y.6
Agarwal, S.7
Iyer, L.M.8
Liu, D.R.9
Aravind, L.10
Rao, A.11
-
50
-
-
74949108515
-
Mutations of e3 ubiquitin ligase cbl family members constitute a novel common pathogenic lesion in myeloid malignancies
-
Makishima H, Cazzolli H, Szpurka H, et al: Mutations of e3 ubiquitin ligase cbl family members constitute a novel common pathogenic lesion in myeloid malignancies. J Clin Oncol 27: 6109-6116, 2009.
-
(2009)
J Clin Oncol
, vol.27
, pp. 6109-6116
-
-
Makishima, H.1
Cazzolli, H.2
Szpurka, H.3
-
51
-
-
66849124925
-
Mutations of polycomb-associated gene ASXL1 in myelodysplastic syndromes and chronic myelomonocytic leukaemia
-
Gelsi-Boyer V, Trouplin V, Adelaide J, et al: Mutations of polycomb-associated gene ASXL1 in myelodysplastic syndromes and chronic myelomonocytic leukaemia. Br J Haematol 145: 788-800, 2009.
-
(2009)
Br J Haematol
, vol.145
, pp. 788-800
-
-
Gelsi-Boyer, V.1
Trouplin, V.2
Adelaide, J.3
-
52
-
-
77952421834
-
Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia
-
Boultwood J, Perry J, Pellagatti A, et al: Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia. Leukemia 24: 1062-1065, 2010.
-
(2010)
Leukemia
, vol.24
, pp. 1062-1065
-
-
Boultwood, J.1
Perry, J.2
Pellagatti, A.3
-
53
-
-
38949123096
-
Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML
-
DOI 10.1182/blood-2007-05-092304
-
Gondek LP, Tiu R, O'Keefe CL, Sekeres MA, Theil KS and Maciejewski JP: Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML. Blood 111: 1534-1542, 2008. (Pubitemid 351213443)
-
(2008)
Blood
, vol.111
, Issue.3
, pp. 1534-1542
-
-
Gondek, L.P.1
Tiu, R.2
O'Keefe, C.L.3
Sekeres, M.A.4
Theil, K.S.5
Maciejewski, J.P.6
-
54
-
-
36148993604
-
Prevalence and prognostic significance of allelic imbalance by single-nucleotide polymorphism analysis in low-risk myelodysplastic syndromes
-
DOI 10.1182/blood-2007-03-079673
-
Mohamedali A, Gäken J, Twine NA, et al: Prevalence and prognostic significance of allelic imbalance by single-nucleotide polymorphism analysis in low-risk myelodysplastic syndromes. Blood 110: 3365-3373, 2007. (Pubitemid 350106331)
-
(2007)
Blood
, vol.110
, Issue.9
, pp. 3365-3373
-
-
Mohamedali, A.1
Gaken, J.2
Twine, N.A.3
Ingram, W.4
Westwood, N.5
Lea, N.C.6
Hayden, J.7
Donaldson, N.8
Aul, C.9
Gattermann, N.10
Giagounidis, A.11
Germing, U.12
List, A.F.13
Mufti, G.J.14
-
55
-
-
70349306857
-
Accurate detection of uniparental disomy and microdeletions by SNP array analysis in myelodysplastic syndromes with normal cytogenetics
-
Heinrichs S, Kulkarni RV, Bueso-Ramos CE, et al: Accurate detection of uniparental disomy and microdeletions by SNP array analysis in myelodysplastic syndromes with normal cytogenetics. Leukemia 23: 1605-1613, 2009.
-
(2009)
Leukemia
, vol.23
, pp. 1605-1613
-
-
Heinrichs, S.1
Kulkarni, R.V.2
Bueso-Ramos, C.E.3
-
56
-
-
9644289387
-
Is targeting Toll-like receptors and their signaling pathway a useful therapeutic approach to modulating cytokine-driven inflammation?
-
Andreakos E, Foxwell B and Feldmann M: Is targeting Toll-like receptors and their signaling pathway a useful therapeutic approach to modulating cytokine-driven inflammation? Immunol Rev 202: 250-265, 2004.
-
(2004)
Immunol Rev
, vol.202
, pp. 250-265
-
-
Andreakos, E.1
Foxwell, B.2
Feldmann, M.3
-
59
-
-
77950629227
-
Expression of Toll-like receptor 9 in bone marrow cells of myelodysplastic syndromes is down-regulated during transformation to overt leukemia
-
Kuninaka N, Kurata M, Yamamoto K, Suzuki S, Umeda S, Kirimura S, Arai A, Nakagawa Y, Suzuki K and Kitagawa M: Expression of Toll-like receptor 9 in bone marrow cells of myelodysplastic syndromes is down-regulated during transformation to overt leukemia. Exp Mol Pathol 88: 293-298, 2010.
-
(2010)
Exp Mol Pathol
, vol.88
, pp. 293-298
-
-
Kuninaka, N.1
Kurata, M.2
Yamamoto, K.3
Suzuki, S.4
Umeda, S.5
Kirimura, S.6
Arai, A.7
Nakagawa, Y.8
Suzuki, K.9
Kitagawa, M.10
-
60
-
-
85047694750
-
EVI1 induces myelodysplastic syndrome in mice
-
DOI 10.1172/JCI200421716
-
Buonamici S, Li D, Chi Y, Zhao R, Wang X, Brace L, Ni H, Saunthararajah Y and Nucifora G: EVI1 induces myelodysplastic syndrome in mice. J Clin Invest 114: 713-719, 2004. (Pubitemid 39582822)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.5
, pp. 713-719
-
-
Buonamici, S.1
Li, D.2
Chi, Y.3
Zhao, R.4
Wang, X.5
Brace, L.6
Ni, H.7
Saunthararajah, Y.8
Nucifora, G.9
-
61
-
-
24344437303
-
Role of nucleophosmin in embryonic development and tumorigenesis
-
DOI 10.1038/nature03915, PII N03915
-
Grisendi S, Bernardi R, Rossi M, Cheng K, Khandker L, Manova K and Pandolfi PP: Role of nucleophosmin in embryonic development and tumorigenesis. Nature 437: 147-153, 2005. (Pubitemid 41613442)
-
(2005)
Nature
, vol.437
, Issue.7055
, pp. 147-153
-
-
Grisendi, S.1
Bernardi, R.2
Rossi, M.3
Cheng, K.4
Khandker, L.5
Manova, K.6
Pandolfi, P.P.7
-
62
-
-
22044450619
-
NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia
-
DOI 10.1182/blood-2004-12-4794
-
Lin YW, Slape C, Zhang Z and Aplan PD: NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukaemia. Blood 106: 287-295, 2005. (Pubitemid 40967204)
-
(2005)
Blood
, vol.106
, Issue.1
, pp. 287-295
-
-
Lin, Y.-W.1
Slape, C.2
Zhang, Z.3
Aplan, P.D.4
-
63
-
-
43249103972
-
AML1 mutations induced MDS and MDS/AML in a mouse BMT model
-
Watanabe-Okochi N, Kitaura J, Ono R, Harada H, Harada Y, Komeno Y, Nakajima H, Nosaka T, Inaba T and Kitamura T: AML1 mutations induced MDS and MDS/AML in a mouse BMT model. Blood 111: 4297-4308, 2008.
-
(2008)
Blood
, vol.111
, pp. 4297-4308
-
-
Watanabe-Okochi, N.1
Kitaura, J.2
Ono, R.3
Harada, H.4
Harada, Y.5
Komeno, Y.6
Nakajima, H.7
Nosaka, T.8
Inaba, T.9
Kitamura, T.10
|