Role of aquaporin 5 in antigen-induced airway inflammation and mucous hyperproduction in mice

Journal of Cellular and Molecular Medicine

Volumn 15, Issue 6, 2011, Pages 1355-1363

  Shen, Yao ^a   Wang, Yaoli ^a,b   Chen, Zhihong ^a   Wang, Diane ^a   Wang, Xiangdong ^a   Jin, Meiling ^a   Bai, Chunxue ^a  

^a FUDAN UNIVERSITY   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Aquaporins; Chronic allergy; House dust mite; Inflammation; Mucin

Indexed keywords

ANTIGEN; AQUAPORIN 5; CYTOKINE; MUC5AC PROTEIN, MOUSE; MUC5B PROTEIN, MOUSE; MUCIN 5AC; MUCIN 5B;

ANIMAL; ARTICLE; ASTHMA; BIOSYNTHESIS; C57BL MOUSE; CHEMISTRY; GENE DELETION; GENETICS; HYPERSENSITIVITY; IMMUNOLOGY; INFLAMMATION; LUNG LAVAGE; METABOLISM; MOUSE; MOUSE MUTANT; MUCUS; PATHOLOGY; PYROGLYPHIDAE; RESPIRATORY SYSTEM; SECRETION; TH2 CELL;

ANIMALS; ANTIGENS; AQUAPORIN 5; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; CYTOKINES; GENE DELETION; HYPERSENSITIVITY; INFLAMMATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUCIN 5AC; MUCIN-5B; MUCUS; PYROGLYPHIDAE; RESPIRATORY SYSTEM; TH2 CELLS;

MUS; PYROGLYPHIDAE;

EID: 79957641857     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2010.01103.x     Document Type: Article

References (29)

1. Bochner BS, Busse WW. Allergy and asthma. J Allergy Clin Immunol. 2005; 115: 953-9.
2. Verkman AS. Role of aquaporins in lung liquid physiology. Respir Physiol Neurobiol. 2007; 159: 324-30.
3. Funaki H, Yamamoto T, Koyama Y, et al Localization and expression of AQP5 in cornea, serous salivary glands, and pulmonary epithelial cells. Am J Physiol. 1998; 275: C1151-7.
4. Ishida N, Hirai SI, Mita S. Immunolocalization of aquaporin homologs in mouse lacrimal glands. Biochem Biophys Res Commun. 1997; 238: 891-5.
5. Song YL, Verkman AS. Aquaporin-5 dependent fluid secretion in airway submucosal glands. J Biol Chem. 2001; 276: 41288-92.
6. Chen ZH, Wang XD, Gao L, et al Regulation of MUC5AC mucin secretion by depletion of AQP5 in SPC-A1 cells. Biochem Biophys Res Commun. 2006; 342: 775-81.
7. Krane CM, Fortner CN, Hand AR, et al Aquaporin 5-deficient mouse lungs are hyperresponsive to cholinergic stimulation. Proc Natl Acad Sci USA. 2001; 98: 14114-9.
8. Towne JE, Harrod KS, Krane CM, et al Decreased expression of aquaporin (AQP)1 and AQP5 in mouse lung after acute viral infection. Am J Respir Cell Mol Biol. 2000; 22: 34-44.
9. Towne JE, Krane CM, Bachurski CJ, et al Tumor necrosis factor-alpha inhibits aquaporin 5 expression in mouse lung epithelial cells. J Biol Chem. 2001; 276: 18657-64.
10. Jiao GY, Li ER, Yu RJ. Decreased expression of AQP1 and AQP5 in acute injured lungs in rats. Chin Med J. 2002; 115: 963-7.
11. Cates EC, Fattouh R, Wattie J, et al Intranasal exposure of mice to house dust mite elicits allergic airway inflammation via a GM-CSF-mediated mechanism. J Immunol. 2004; 173: 6384-92.
12. Moore M, Ma TH, Yang BX, et al Tear secretion by lacrimal glands in transgenic mice lacking water channels AQP1, AQP3, AQP4 and AQP5. Exp Eye Res. 2000; 70: 557-62.
13. Underwood S, Foster M, Raeburn D, et al Time-course of antigen-induced airway inflammation in the guinea-pig and its relationship to airway hyperresponsiveness. Eur Respir J. 1995; 8: 2104-13.
14. Wang K, Feng YL, Wen FQ, et al Decreased expression of human aquaporin-5 correlated with mucus overproduction in airways of chronic obstructive pulmonary disease. Acta Pharmacol Sin. 2007; 28: 1166-74.
15. Lee C, Kolesnik TB, Caminschi I, et al Suppressor of cytokine signalling 1 (SOCS1) is a physiological regulator of the asthma response. J Allergy Clin Immunol. 2009; 39: 897-907.
16. Krane CM, Deng BJ, Mutyam V, et al Altered regulation of aquaporin gene expression in allergen and IL-13-induced mouse models of asthma. Cytokine. 2009; 46: 111-8.
17. Karras JG, Crosby JR, Guha M, et al Anti-inflammatory activity of inhaled IL-4 receptor-alpha antisense oligonucleotide in mice. Am J Respir Cell Mol Biol. 2007; 36: 276-85.
18. Walter DM, McIntire JJ, Berry G, et al Critical role for IL-13 in the development of allergen-induced airway hyperreactivity. J Immunol. 2001; 167: 4668-75.
19. Tomkinson A, Duez C, Cieslewicz G, et al A murine IL-4 receptor antagonist that inhibits IL-4-and IL-13-induced responses prevents antigen-induced airway eosinophilia and airway hyperresponsiveness. J Immunol. 2001; 166: 5792-800.
20. Rogers DF. Physiology of airway mucus secretion and pathophysiology of hypersecretion. Respir Care. 2007; 52: 1134-49.
21. Henke MO, John G, Germann M, et al MUC5AC and MUC5B mucins increase in cystic fibrosis airway secretions during pulmonary exacerbation. Am J Respir Crit Care Med. 2007; 175: 816-21.
22. Wang GF, Dong CL, Tang GS, et al Membrane water permeability related to antigen-presenting function of dendritic cells. J Allergy Clin Immunol. 2008; 153: 410-9.
23. Moon C, Rousseau R, Soria JC, et al Aquaporin expression in human lymphocytes and dendritic cells. Am J Hematol. 2004; 75: 128-33.
24. Bousquet J, Bieber T, Fokkens W, et al Important questions in allergy: novel research areas. Allergy. 2008; 63: 143-7.
25. Skowron-Zwarg M, Boland S, Caruso N, et al Interleukin-13 interferes with CFTR and AQP5 expression and localization during human airway epithelial cell differentiation. Exp Cell Res. 2007; 313: 2695-702.
26. Pedersen PS, Braunstein TH, Jorgensen A, et al Stimulation of aquaporin-5 and transepithelial water permeability in human airway epithelium by hyperosmotic stress. Pflugers Arch. 2007; 453: 777-85.
27. Ma TH, Song YL, Gillespie A, et al Defective secretion of saliva in transgenic mice lacking aquaporin-5 water channels. J Biol Chem. 1999; 274: 20071-4.
28. Sidhaye V, Hoffert JD, King LS. cAMP has distinct acute and chronic effects on Aquaporin-5 in lung epithelial cells. J Biol Chem. 2005; 280: 3590-6.
29. Chen ZH, Zhu R, Bai L, et al Downregulation of aquaporin 5 induced by vector-based short hairpin RNA and its effect on MUC5AC gene expression in human airway submucosal gland cells. Respir Physiol Neurobiol. 2006; 152: 197-203.