Gemcitabine monotherapy associated with posterior reversible encephalopathy syndrome

Case Reports in Oncology

Volumn 4, Issue 1, 2011, Pages 82-87

  Marrone, Luiz Carlos Porcello ^a   Marrone, Bianca Fontana ^b   De La Puerta Raya, Julia ^a   Gadonski, Giovani ^a   Da Costa, Jaderson Costa ^a  

^a PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

Author keywords

Chemotherapy; Gemcitabine; Posterior reversible encephalopathy syndrome

Indexed keywords

CREATININE; GEMCITABINE; PHENYTOIN;

AGED; ANTICONVULSANT THERAPY; ARTICLE; BLURRED VISION; CANCER ADJUVANT THERAPY; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; CREATININE BLOOD LEVEL; DISEASE SEVERITY; FEMALE; FOLLOW UP; HEADACHE; HUMAN; MULTIPLE CYCLE TREATMENT; NEUROIMAGING; OCCIPITAL LOBE; PANCREAS ADENOCARCINOMA; PANCREATICODUODENECTOMY; POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME; PRIORITY JOURNAL; TEMPORAL LOBE; TONIC CLONIC SEIZURE;

EID: 79957624838     PISSN: None     EISSN: 16626575     Source Type: Journal    
DOI: 10.1159/000324581     Document Type: Article

References (43)

1. Hinchey J, Chaves C, Appignani B, Breen J, Pao L, Wang A, Pessin MS, Lamy C, Mas JL, Caplan LR: A reversible posterior leukoencephalopathy syndrome. N Engl J Med 1996;334:494-500. (Pubitemid 26067737)
2. Sheth RD, Riggs JE, Bodenstenier JB, Gutierrez AR, Ketonen LM, Ortiz OA: Parietal occipital edema in hypertensive encephalopathy: a pathogenic mechanism. Eur Neurol 1996;36:25-28.
3. Hauser RA, Lacey DM, Knight MR: Hypertensive encephalopathy: magnetic resonance imaging demonstration of reversible cortical and white matter lesions. Arch Neurol 1988;45:1078-1083.
4. Weingarten K, Barbut D, Filippi C, Zimmerman RD: Acute hypertensive encephalopathy: findings on spinecho and gradient-echo MR imaging. AJR Am J Roentgenol 1994;162:665-670. (Pubitemid 24093575)
5. Schwartz RB, Jones KM, Kalina P, Bajakian RL, Mantello MT, Garada B, Holman BL: Hypertensive encephalopathy: findings on CT, MR imaging, and SPECT imaging in 14 cases. AJR Am J Roentgenol 1992;159:379-383.
6. Fisher M, Maister B, Jacobs R: Hypertensive encephalopathy: diffuse reversible white matter CT abnormalities. Ann Neurol 1985;18:268-270.
7. Lewis LK, Hinshaw DB Jr, Will AD, Hasso AN, Thompson JR: CT and angiographic correlation of severe neurological disease in toxemia of pregnancy. Neuroradiology 1988;30:59-64. (Pubitemid 18057854)
8. Port JD, Beauchamp NJ Jr: Reversible intracerebral pathologic entities mediated by vascular autoregulatory dysfunction. Radiographics 1998;18:253-267.
9. Strandgaard S, Paulson OB: Cerebral autoregulation. Stroke 1984;15:413-416. (Pubitemid 14105951)
10. Nag S, Robertson DM, Dinsdale HB: Cerebral cortical changes in acute experimental hypertension: an ultrastructural study. Lab Invest 1977;36:150-161. (Pubitemid 8056209)
11. Schwartz RB, Mulkern RV, Gudbjartsson H, Jolesz F: Diffusion-weighted MR imaging in hypertensive encephalopathy: clues to pathogenesis. Am J Neuroradiol 1998;19:859-862. (Pubitemid 30415767)
12. Mukherjee P, McKinstry RC: Reversible posterior leukoencephalopathy syndrome: evaluation with diffusiontensor MR imaging. Radiology 2001;219:756-765. (Pubitemid 32476268)
13. Schaefer PW, Buonanno FS, Gonzalez RG, Schwamm LH: Diffusion-weighted imaging discriminates between cytotoxic and vasogenic edema in a patient with eclampsia. Stroke 1997;28:1082-1085. (Pubitemid 27209161)
14. Coley SC, Porter DA, Calamante F, Chong WK, Connelly A: Quantitative MR diffusion mapping and cyclosporine-induced neurotoxicity. AJNR Am J Neuroradiol 1999;20:1507-1510. (Pubitemid 29455876)
15. Ay H, Buonanno FS, Schaefer PW, Le DA, Wang B, Gonzalez RG, Koroshetz WJ: Posterior leukoencephalopathy without severe hypertension: utility of diffusion-weighted MRI. Neurology 1998;51:1369-1376. (Pubitemid 28520560)
16. Donaldson JO: The brain in eclampsia. Hypertens Pregnancy 1994;13:115.
17. Roberts JM, Redman CWG: Pre-eclampsia: more than pregnancy-induced hypertension. Lancet 1993;341:1447-1451; erratum 1993;342:504. (Pubitemid 23161452)
18. Schwartz RB, Feske SK, Polak JF, DeGirolami U, Iaia A, Beckner KM, Bravo SM, Klufas RA, Chai RY, Repke JT: Preeclampsia-eclampsia: clinical and neuroradiographic correlates and insights into the pathogenesis of hypertensive encephalopathy. Radiology 2000;217:371-376.
19. Colosimo C Jr, Fileni A, Moschini M, Guerrini P: CT findings in eclampsia. Neuroradiology 1985;27:313-317. (Pubitemid 15030944)
20. Naheedy MH, Biller J, Schiffer M, Azar-Kia B, Gaianopoulous J, Zarandy S: Toxemia of pregnancy: cerebral CT findings. J Comput Assist Tomogr 1985;9:497-501.
21. Ishimori ML, Pressman BD, Wallace DJ, Weisman MH: Posterior reversible encephalopathy syndrome: another manifestation of CNS SLE? Lupus 2007;16:436-443. (Pubitemid 47122218)
22. Punaro M, Abou-Jaoude P, Cimaz R, Ranchin B: Unusual neurologic manifestations (II): posterior reversible encephalopathy syndrome (PRES) in the context of juvenile systemic lupus erythematosus. Lupus 2007;16:576-579. (Pubitemid 47359991)
23. Baizabal-Carvallo JF, Barragán-Campos HM, Padilla-Aranda HJ, Alonso-Juarez M, Estañol B, Cantú-Brito C, García-Ramos G: Posterior reversible encephalopathy syndrome as a complication of acute lupus activity. Clin Neurol Neurosurg 2009;111:359-363.
24. Bartynski WS, Tan HP, Boardman JF, Shapiro R, Marsh JW: Posterior reversible encephalopathy syndrome after solid organ transplantation. AJNR Am J Neuroradiol 2008;29:924-930. (Pubitemid 351684968)
25. Hourani R, Abboud M, Hourani M, Khalifeh H, Muwakkit S: L-asparaginase-induced posterior reversible encephalopathy syndrome during acute lymphoblastic leukemia treatment in children. Neuropediatrics 2008;39:46-50. (Pubitemid 351828318)
26. Bartynski WS, Boardman JF, Zeigler ZR, Shadduck RK, Lister J: Posterior reversible encephalopathy syndrome in infection, sepsis, and shock. AJNR Am J Neuroradiol 2006;27:2179-2190. (Pubitemid 44788652)
27. Onder AM, Lopez R, Teomete U, Francoeur D, Bhatia R, Knowbi O, Hizaji R, Chandar J, Abitbol C, Zilleruelo G: Posterior reversible encephalopathy syndrome in the pediatric renal population. Pediatr Nephrol 2007;22:1921-1929. (Pubitemid 47506233)
28. Gokce M, Dogan E, Nacitarhan S, Demirpolat G: Posterior reversible encephalopathy syndrome caused by hypertensive encephalopathy and acute uremia. Neurocrit Care 2006;4:133-136. (Pubitemid 43793343)
29. Russell MT, Nassif AS, Cacayorin ED, Awwad E, Perman W, Dunphy F: Gemcitabine-associated posterior reversible encephalopathy syndrome: MR imaging and MR spectroscopy findings. Magn Reson Imaging 2001;19:129-132. (Pubitemid 32274125)
30. Duncan R, Hadley D, Bone I, Symonds EM, Worthington BS, Rubin PC: Blindness in eclampsia: CT and MR imaging. J Neurol Neurosurg Psychiatry 1989;52:899-902. (Pubitemid 19181352)
31. Truwit CL, Denaro CP, Lake JR, DeMarco T: MR imaging of reversible cyclosporin A-induced neurotoxicity. AJNR Am J Neuroradiol 1991;12:651-659.
32. Lamy C, Oppenheim C, Méder JF, Mas JL: Neuroimaging in posterior reversible encephalopathy syndrome. J Neuroimaging 2004;14:89-96. (Pubitemid 38391815)
33. Sanders TG, Clayman DA, Sanchez-Ramos L, Vines FS, Russo L: Brain in eclampsia: MR imaging with clinical correlation. Radiology 1991;180:475-478.
34. De Klippel N, Sennesael J, Lamote J, Ebinger G, de Keyser J: Cyclosporin leukoencephalopathy induced by intravenous lipid solution. Lancet 1992;339:1114.
35. Rajasekhar A, George TJ Jr: Gemcitabine-induced reversible posterior leukoencephalopathy syndrome: a case report and review of literature. Oncologist 2007;12:1332-1335. (Pubitemid 350232606)
36. Cooney MJ, Bradley WG, Symko SC, Patel ST, Groncy PK: Hypertensive encephalopathy: complication in children treated for myeloproliferative disorders - report of three cases. Radiology 2000;214:711-716. (Pubitemid 30115369)
37. Morris EB, Laningham FH, Sandlund JT, Khan RB: Posterior reversible encephalopathy syndrome in children with cancer. Pediatr Blood Cancer 2007;48:152-159. (Pubitemid 44958271)
38. Sánchez-Carpintero R, Narbona J, López de Mesa R, Arbizu J, Sierrasesúmaga L: Transient posterior encephalopathy induced by chemotherapy in children. Pediatr Neurol 2001;24:145-148. (Pubitemid 32280299)
39. Pihko H, Tyni T, Virkola K, Valanne L, Sainio K, Hovi L, Saarinen UM: Transient ischemic cerebral lesions during induction chemotherapy for acute lymphoblastic leukemia. J Pediatr 1993;123:718-724. (Pubitemid 23316422)
40. Burris HA 3rd, Moore MJ, Andersen J, Green MR, Rothenberg ML, Modiano MR, Cripps MC, Portenoy RK, Storniolo AM, Tarassoff P, Nelson R, Dorr FA, Stephens CD, Von Hoff DD: Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol 1997;15:2403-2413. (Pubitemid 27251144)
41. Plunkett W, Huang P, Xu YZ, Heinemann V, Grundewald R, Gandhi V: Gemcitabine: metabolism, mechanisms of action, and self-potentiation. Semin Oncol 1995;22(suppl 11):3-10.
42. Gemzar- (gemcitabine HCl for injection) [package insert]. Indianapolis, Eli Lilly and Company, 2006.
43. Kwon EJ, Kim SW, Kim KK, Seo HS, Kim do Y: A case of gemcitabine and cisplatin associated posterior reversible encephalopathy syndrome. Cancer Res Treat 2009;41:53-55.