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Volumn 27, Issue 6, 2011, Pages 659-667

Beneficial effects of a switch to a lopinavir/ritonavir-containing regimen for patients with partial or no immune reconstitution with highly active antiretroviral therapy despite complete viral suppression

Author keywords

[No Author keywords available]

Indexed keywords

LOPINAVIR PLUS RITONAVIR; VIRUS RNA;

EID: 79957597321     PISSN: 08892229     EISSN: 19318405     Source Type: Journal    
DOI: 10.1089/aid.2010.0230     Document Type: Article
Times cited : (5)

References (47)
  • 2
    • 0037108381 scopus 로고    scopus 로고
    • + cell counts after successful virologic suppression
    • DOI 10.1086/342695
    • Dronda F, Moreno S, Moreno A, et al.: Long-term outcomes among antiretroviral-naive human immunodeficiency virusinfected patients with small increases in CD4+ cell counts after successful virological suppression. Clin Infect Dis 2002;35:1005-1009 (Pubitemid 35178319)
    • (2002) Clinical Infectious Diseases , vol.35 , Issue.8 , pp. 1005-1009
    • Dronda, F.1    Moreno, S.2    Moreno, A.3    Casado, J.L.4    Perez-Elias, M.J.5    Antela, A.6
  • 5
    • 0032869708 scopus 로고    scopus 로고
    • Reduction in T cell apoptosis in patients with HIV disease following antiretroviral therapy
    • DOI 10.1006/clim.1999.4770
    • Chavan SJ, Tamma SL, Kaplan M, et al.: Reduction in T cell apoptosis in patients with HIV disease following antiretroviral therapy. Clin Immunol 1999;93(1):24-33 (Pubitemid 29459959)
    • (1999) Clinical Immunology , vol.93 , Issue.1 , pp. 24-33
    • Chavan, S.J.1    Tamma, S.L.2    Kaplan, M.3    Gersten, M.4    Pahwa, S.G.5
  • 6
    • 0032695189 scopus 로고    scopus 로고
    • Highly active anti-retroviral therapy HAART is associated with a lower level of CD4+ T cell apoptosis in HIV-infected patients
    • Roger PM, Breittmayer JP, Arlotto C, et al.: Highly active anti-retroviral therapy (HAART) is associated with a lower level of CD4+ T cell apoptosis in HIV-infected patients. Clin Exp Immunol 1999;118(3):412-416
    • (1999) Clin. Exp. Immunol. , vol.118 , Issue.3 , pp. 412-416
    • Roger, P.M.1    Breittmayer, J.P.2    Arlotto, C.3
  • 7
    • 0033179343 scopus 로고    scopus 로고
    • + T cells and decreases their susceptibility to apoptosis in vitro and in vivo
    • Sloand EM, Kumar PN, et al.: Human immunodeficiency virus type 1 protease inhibitor modulates activation of peripheral blood CD4(+) T cells and decreases their susceptibility to apoptosis in vitro and in vivo. Blood 1999;94(3): 1021-1027 (Pubitemid 29361834)
    • (1999) Blood , vol.94 , Issue.3 , pp. 1021-1027
    • Sloand, E.M.1    Kumar, P.N.2    Kim, S.3    Chaudhuri, A.4    Weichold, F.F.5    Young, N.S.6
  • 8
    • 79957614361 scopus 로고    scopus 로고
    • Panel on antiretroviral guidelines for adult and adolescents: Guidelines for the use of antiretroviral agents in HIV- 1-infected adults and adolescents
    • December 1
    • Panel on Antiretroviral Guidelines for Adult and Adolescents: Guidelines for the use of antiretroviral agents in HIV- 1-infected adults and adolescents. Department of Health and Human Services. December 1, 2009
    • (2009) Department of Health and Human Services
  • 9
    • 0037169169 scopus 로고    scopus 로고
    • Different degree of immune recovery using antiretroviral regimens with protease inhibitors or non-nucleosides
    • DOI 10.1097/00002030-200201250-00014
    • Barreiro P, Soriano V, Casas E, et al.: Different degree of immune recovery using antiretroviral regimens with protease inhibitors or non-nucleosides. AIDS 2002;16:245-249 (Pubitemid 34118572)
    • (2002) AIDS , vol.16 , Issue.2 , pp. 245-249
    • Barreiro, P.1    Soriano, V.2    Casas, E.3    Gonzalez-Lahoz, J.4
  • 10
    • 0037169269 scopus 로고    scopus 로고
    • Duration and predictors of CD4 T-cell gains in patients who continue combination therapy despite detectable plasma viremia
    • DOI 10.1097/00002030-200201250-00009
    • Deeks SG, Barbour JD, Grant RM, et al.: Duration and predictors of CD4 T cell gain in patients who continue combination therapy despite detectable plasma viremia. AIDS 2002;16(2):201-207 (Pubitemid 34118567)
    • (2002) AIDS , vol.16 , Issue.2 , pp. 201-207
    • Deeks, S.G.1    Barbour, J.D.2    Grant, R.M.3    Martin, J.N.4
  • 11
    • 33750253867 scopus 로고    scopus 로고
    • An updated systematic overview of triple combination therapy in antiretroviral-naive HIV-infected adults
    • DOI 10.1097/01.aids.0000247578.08449.ff, PII 0000203020061024000007
    • Bartlett JA, Fath MJ, DeMasi R, et al.: An updated systematic review of triple combination therapy in antiretroviral-naive HIV-infected patients. AIDS 2006;20:2051-2064 (Pubitemid 44611058)
    • (2006) AIDS , vol.20 , Issue.16 , pp. 2051-2064
    • Bartlett, J.A.1    Fath, M.J.2    DeMasi, R.3    Hermes, A.4    Quinn, J.5    Mondou, E.6    Rousseau, F.7
  • 13
    • 33846439783 scopus 로고    scopus 로고
    • + cell count 6 years after commencement of highly active antiretroviral therapy in persons with sustained virologic suppression
    • DOI 10.1086/510746
    • Moore RD and Keruly JC: CD4+ cell count 6 years after commencement of highly active antiretroviral therapy in persons with sustained virologic suppression. Clin Infect Dis 2007;44:441-446 (Pubitemid 46147630)
    • (2007) Clinical Infectious Diseases , vol.44 , Issue.3 , pp. 441-446
    • Moore, R.D.1    Keruly, J.C.2
  • 15
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti I, Migliorati G, Pagliacci F, et al.: A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 1991;139:271-279
    • (1991) J. Immunol. Methods , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, F.3
  • 16
    • 0035822946 scopus 로고    scopus 로고
    • Persistence of intracellular HIV-1 mRNA correlates with HIV-1-specific immune responses in infected subjects on stable HAART
    • DOI 10.1097/00002030-200109070-00005
    • Patterson BK, McCallister S, Schutz M, et al.: Persistence of intracellular HIV-1 mRNA correlates with HIV-1 specific immune responses in infected subjects on stable HAART. AIDS 2001;15:1635-1641 (Pubitemid 32923062)
    • (2001) AIDS , vol.15 , Issue.13 , pp. 1635-1641
    • Patterson, B.K.1    McCallister, S.2    Schutz, M.3    Siegel, J.N.4    Shults, K.5    Flener, Z.6    Landay, A.7
  • 17
    • 1042300003 scopus 로고    scopus 로고
    • The prognostic importance of changes in CD4+ cell count and HIV-1 RNA level in women after initiating highly active antiretroviral therapy
    • Anastos K, Barron Y, Cohen M, et al.: The prognostic importance of changes in CD4+ cell count and HIV-1 RNA level in women after initiating highly active antiretroviral therapy. Ann Intern Med 2004;140:256-264
    • (2004) Ann. Intern. Med. , vol.140 , pp. 256-264
    • Anastos, K.1    Barron, Y.2    Cohen, M.3
  • 18
    • 0035882308 scopus 로고    scopus 로고
    • Initial virological and immunologic response to highly active antiretroviral therapy predicts long-term clinical outcome
    • DOI 10.1086/321900
    • Kitchen CM, Kitchen SG, Dubin JA, et al.: Initial virological and immunologic response to highly active antiretroviral therapy predicts long-term clinical outcome. Clin Infect Dis 2001;33:466-472 (Pubitemid 32709577)
    • (2001) Clinical Infectious Diseases , vol.33 , Issue.4 , pp. 466-472
    • Kitchen, C.M.1    Kitchen, S.G.2    Dubin, J.A.3    Gottlieb, M.S.4
  • 19
    • 16744365520 scopus 로고    scopus 로고
    • CD4 cell counts at the third month of HAART may predict clinical failure
    • Monforte Ad'A, Tesotri V, Adonri F, et al.: CD4 cell counts at the third month of HAART may predict clinical failure. AIDS 1999;13:1669-1676
    • (1999) AIDS , vol.13 , pp. 1669-1676
    • Monforte, Ad'A.1    Tesotri, V.2    Adonri, F.3
  • 20
    • 0034687071 scopus 로고    scopus 로고
    • Clinical outcome of patients with HIV-1 infection according to immunologic and virologic response after 6 months of highly active antiretroviral therapy
    • Brabar S, Le Moing V, Goujard C, et al.: Clinical outcome of patients with HIV-1 infection according to immunologic and virologic response after 6 months of highly active antiretroviral therapy. Ann Intern Med 2000;133:401-410
    • (2000) Ann. Intern. Med. , vol.133 , pp. 401-410
    • Brabar, S.1    Le Moing, V.2    Goujard, C.3
  • 23
    • 85062055676 scopus 로고    scopus 로고
    • Liver-related deaths in persons infected with the human immunodeficiency virus the D:A:D study
    • DOI 10.1001/archinte.166.15.1632
    • Weber R, Sabin CA, Friis-Moller N, et al.:, for the Data Collection on Adverse Events of Anti-HIV Drugs Study Group: Liver-related deaths in persons infected with the human immunodeficiency virus. The D:A:D Study. Arch Intern Med 2006;166(15):1632-1641 (Pubitemid 44232373)
    • (2006) Archives of Internal Medicine , vol.166 , Issue.15 , pp. 1632-1641
    • Weber, R.1
  • 25
    • 79957597515 scopus 로고    scopus 로고
    • 3 reach the same mortality rates as general population
    • APROCO Aquitaine Study Groups France. 10th European AIDS Conference. Dublin Ireland,2005 Poster PE184/8
    • 3 reach the same mortality rates as general population: APROCO and Aquitaine cohorts, France. 10th European AIDS Conference. Dublin, Ireland, 2005 (Poster PE184/8).
    • APROCO and Aquitaine Cohorts
    • Lewden, C.1
  • 27
    • 0034523322 scopus 로고    scopus 로고
    • Increased levels of activated subsets of CD4 T cells add to the prognostic value of low CD4 T cell counts in a cohort of HIV-infected drug users
    • DOI 10.1097/00002030-200012220-00003
    • Carbone J, Gil J, Benito JM, et al.: Increased levels of activated subsets of CD4+ T cells add to the prognostic value of low CD4+ counts in a cohort of HIV-infected drug users. AIDS 2000;14:2823-2829 (Pubitemid 32042745)
    • (2000) AIDS , vol.14 , Issue.18 , pp. 2823-2829
    • Carbone, J.1    Gil, J.2    Benito, J.M.3    Navarro, J.4    Munoz-Fernandez, A.5    Bartolome, J.6    Zabay, J.M.7    Lopez, F.8    Fernandez-Cruz, E.9
  • 29
    • 0038701685 scopus 로고    scopus 로고
    • + T cell gains in human immunodeficiency vires-infected patients with sustained viral suppression during antiretroviral therapy
    • DOI 10.1086/374786
    • Hunt PW, Martin JN, Sinclair E, et al.: T cell activation is associated with lower CD4+ T cells gains in human immunodeficiency virus-infected patients with sustained suppression during antiretroviral therapy. J Infect Dis 2003; 187:1534-1543 (Pubitemid 36578959)
    • (2003) Journal of Infectious Diseases , vol.187 , Issue.10 , pp. 1534-1543
    • Hunt, P.W.1    Martin, J.N.2    Sinclair, E.3    Bredt, B.4    Hagos, E.5    Lampiris, H.6    Deeks, S.G.7
  • 30
    • 79957621988 scopus 로고    scopus 로고
    • Immunogenetics and immune reconstitution during potent antiretroviral therapy: NWCS 233 an analysis of AACTG protocol A5001 3rd IAS Conference on
    • July Rio de Janeiro. Abstract MoOa0303
    • Haas D, Geraghty D, Andersen J, et al.: Immunogenetics and immune reconstitution during potent antiretroviral therapy: NWCS 233, an analysis of AACTG protocol A5001 3rd IAS Conference on HIV Pathogenesis and Treatment. 2005, July 24-27, Rio de Janeiro. Abstract MoOa0303
    • (2005) HIV Pathogenesis and Treatment , pp. 24-27
    • Haas, D.1    Geraghty, D.2    Andersen, J.3
  • 31
    • 0035816396 scopus 로고    scopus 로고
    • Discordant CD4+ T lymphocyte responses to antiretroviral therapy for HIV infection are associated with ex vivo apoptosis
    • Pitrak DL, Bolanos J, Hershow R, et al.: Discordant CD4+ T lymphocyte responses to antiretroviral therapy for HIV infection are associated with ex vivo apoptosis. AIDS 2001; 15(10):1317-1391
    • (2001) AIDS , vol.15 , Issue.10 , pp. 1317-1391
    • Pitrak, D.L.1    Bolanos, J.2    Hershow, R.3
  • 32
    • 33748052966 scopus 로고    scopus 로고
    • Comparative analysis of T-cell turnover and homeostatic parameters in HIV-infected patients with discordant immune-virological responses to HAART
    • Marchetti G, Gori A, Casabianca A, et al.: Comparative analysis of T-cell turnover and homeostatic parameters in HIV-infected patients with discordant immune-virological responses to HAART. AIDS 2006:20(13):11727-11736
    • (2006) AIDS , vol.20 , Issue.13 , pp. 11727-11736
    • Marchetti, G.1    Gori, A.2    Casabianca, A.3
  • 37
    • 0037131199 scopus 로고    scopus 로고
    • Interleukin-2 accelerates CD4 cell reconstitution in HIV-infected patients with severe immunosuppression despite highly active antiretroviral therapy
    • Katlama C, Carcelain G, Duvivier C, et al.: Interleukin-2 accelerates CD4 cell reconstitution in HIV-infected patients with severe immunosuppression despite highly active antiretroviral therapy: The ILSTIM study-ANRS082 AIDS 2002; 16(15):2027-2034
    • ILSTIM Study-ANRS082 AIDS2002 , vol.16 , Issue.15 , pp. 2027-2034
    • Katlama, C.1    Carcelain, G.2    Duvivier, C.3
  • 38
    • 70350441282 scopus 로고    scopus 로고
    • Interleukin-2 therapy in patients with HIV infection
    • INSIGHT-ESPRIT Study Group SILCAAT Scientific Committee
    • INSIGHT-ESPRIT Study Group; SILCAAT Scientific Committee, Abrams D, Levy Y, Losso MH, et al.: Interleukin-2 therapy in patients with HIV infection. N Engl J Med 2009; 361(16):1548-1549
    • (2009) N. Engl. J. Med. , vol.361 , Issue.16 , pp. 1548-1549
    • Abrams, D.1    Levy, Y.2    Losso, M.H.3
  • 40
    • 7744226997 scopus 로고    scopus 로고
    • Randomized placebo-controlled trial of abacavir intensification in HIV-1 infected adults with plasma HIV RNA <500 copies/mL
    • for the ACTG 372A Study Team February 8-11 2004 San Francisco, CA. Abstract 56
    • Hammer S, Bassett R, Fischl M, et al., for the ACTG 372A Study Team: Randomized, placebo-controlled trial of abacavir intensification in HIV-1 infected adults with plasma HIV RNA <500 copies/mL 11th Conference on Retroviruses and Opportunistic Infections for the ACTG 372A Study Team February 8-11 2004 San Francisco, CA. Abstract 56
    • 11th Conference on Retroviruses and Opportunistic Infections
    • Hammer, S.1    Bassett, R.2    Fischl, M.3
  • 41
    • 33646881763 scopus 로고    scopus 로고
    • Relationship between antiretrovirals used as part of a cART regimen and CD4 cell count increases in patients with suppressed viremia
    • DOI 10.1097/01.aids.0000226954.95094.39, PII 0000203020060512000007
    • Mocroft A, Phillips AN, Lederberger B, et al.: Relationship between antiretrovirals used as part of a HAART regimen and CD4cell count increases in patients with suppressed viremia. AIDS 2006;20(8):1141-1150 (Pubitemid 43786102)
    • (2006) AIDS , vol.20 , Issue.8 , pp. 1141-1150
    • Mocroft, A.1    Phillips, A.N.2    Ledergerber, B.3    Katlama, C.4    Chiesi, A.5    Goebel, F.-D.6    Knysz, B.7    Antunes, F.8    Reiss, P.9    Lundgren, J.D.10
  • 43
    • 22744437219 scopus 로고    scopus 로고
    • In vitro and in vivo effects of HIV protease inhibitors on apoptosis
    • DOI 10.1038/sj.cdd.4401580
    • Badley AD: In vitro and in vivo effects of HIV protease inhibitors on apoptosis. Cell Death Differ 2005;(Suppl 1):924-931 (Pubitemid 41030607)
    • (2005) Cell Death and Differentiation , vol.12 , Issue.SUPPL. 1 , pp. 924-931
    • Badley, A.D.1
  • 44
    • 0035883068 scopus 로고    scopus 로고
    • Antiapoptotic mechanism of HIV protease inhibitors: Preventing mitochondrial transmembrane potential loss
    • Phenix BN, Lum JJ, Nie Z, et al.: Antiapoptotic mechanism of HIV protease inhibitors: Preventing mitochondrial transmembrane potential loss. Blood 2001;98:1078-1085
    • (2001) Blood , vol.98 , pp. 1078-1085
    • Phenix, B.N.1    Lum, J.J.2    Nie, Z.3
  • 47
    • 40049103926 scopus 로고    scopus 로고
    • HIV Protease inhibitors impact on apoptosis
    • DOI 10.2174/157340608783331443
    • Rizza SA and Badley AD: HIV protease inhibitors impact on apoptosis. Med Chem 2008;41(1):75-79 (Pubitemid 351320923)
    • (2008) Medicinal Chemistry , vol.4 , Issue.1 , pp. 75-79
    • Rizza, S.A.1    Badley, A.D.2


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