Spasmolytic effect of root and aerial parts extract of Pycnocycla spinosa on neural stimulation of rat ileum

Research in Pharmaceutical Sciences

Volumn 6, Issue 1, 2011, Pages

  Sadraei, Hassan ^a   Asghari, G ^a   Poorkhosravi, R ^a  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Anti spasmodic; Electrical field stimulation; Ileum; Pycnocycla spinosa

Indexed keywords

ATROPINE; LIDOCAINE; NIFEDIPINE; PLANT EXTRACT; POTASSIUM CHLORIDE; PYCNOCYCLA SPINOSA EXTRACT; SPASMOLYTIC AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DEPTH STIMULATION; CONTROLLED STUDY; DRUG ACTIVITY; ELECTROSTIMULATION; IC 50; ILEUM; MEDICINAL PLANT; NONHUMAN; PLANT; PLANT ROOT; PYCNOCYCLA SPINOSA; RAT; SPASMOLYSIS;

EID: 79957593704     PISSN: 17355362     EISSN: 17359414     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Mozaffarian V. A dictionary of Iranian plant names. Tehran: Farhang Moaser; 1996. p. 443-444.
2. Syder JH, Merson MH. The magnitude of the global problem of acute diarrhoeal disease: a review of active surveillance data. Bull WHO. 1982;60:605-613. (Pubitemid 13200473)
3. Sadraei H, Asghari G, Naddafi A. Relaxant effect of essential oil and hydro-alcoholic extract of Pycnocycla spinosa Decne. exBoiss. on ileum contractions. Phytother Res. 2003;17:645-649. (Pubitemid 36781741)
4. Sadraei H, Asghari G, Hekmatti AA. Antispasmodic effect of three fractions of hydroalcoholic extract of Pycnocycla spinosa. J Ethnopharmacol. 2003;86:187-190. (Pubitemid 36542875)
5. Sadraei H, Asghari G, Khazael M. Relaxant effect of four fractions separated from alkaloid extract of Pycnocycla spinosa on rat isolated ileum. Res Pharm Sci. 2008;3:79-86.
6. Seifollahkhani A. Pharmacognostic studies of Pycnocycla nodiflora Decne. exBoiss. The 7th seminar of Iranian Pharmacy Students. Isfahan; 2001. p. 184.
7. Ekdandi S. Medicinal herbs of Chhattisgarh, India having less known traditional uses (Pycnocyla glauca, family Apiceae). A letter to American Botanical. Available from: URL:http://www.botanical.com/site/column-poudhia/ articles/878htm l. 2007.
8. Ahmadi L, Mirza M. Volatile constituents of the essential oil of Pycnocyla spinosa Decne ex.Boiss from Iran. J Essent Oil Res. 1998;10:197-198. (Pubitemid 128483416)
9. Asgahri G, Hoshfar G, Mahmoudi Z. Seasonal variation of mono- and sesquiterpenes in the essential oil of Pycnocyla spinosa Decne. exBoiss. Iranian J Pharm Res. 2002;1:61-63.
10. Jalili A, Jamzad Z. Red data book of Iran, a preliminary survey of endemic, rare and endangered plant species in Iran. Tehran: Research Institute of Forests and Rangelands; 1999. p. 689-690.
11. Sadraei H, Asghari G, Shams M. Anti-diarrhoeal action of hydroalcoholic extract of Pycnocycla spinosa in comparison with loperamide and dicyclomine. Iranian J Pharm Res. In press.
12. Sadraei H, Asghari G, Andisha M. Anti-spasmodic effect of Pycnocycla spinosa seed and aerial part extracts on rat ileum and uterus smooth muscle contractions. Daru. 2008;13:160-163.
13. Sadraei H, Asghari G, Arabzadah A. Effect of hydroalcoholic extract of Pycnocycla spinosa on rat isolated bladder contraction. Iranian J Pharm Res. 2004;4:237-241.
14. Sadraei H, Asghari G, Hajhashemi V, Nezami M. Evalutaion of cardiovascular effect of Pycnocycla spinosa Decne. exBoiss., var. spinosa extracts in anaensthetized rat. Daru. 2008;14:11-14. (Pubitemid 43971928)
15. Samuelsson G. Drugs of natural origin. 4th ed. Stockholm: Swedish Pharmaceutical Press; 1999. p. 48-49.
16. Eglen RM, Whiting RL. Competitive and noncompetitive antatgonism exhibited by selective antagonists at atrial and ileal muscarinic receptor subtypes. Br J Pharmacol. 1987;90:701-707. (Pubitemid 17099404)
17. Kunze WA, Furness JB. The enteric nervous system and regulation of intestinal motility. Ann Rev Physiol. 1999;61:117-142. (Pubitemid 29143166)
18. Katzung BG. Introduction to autonomic pharmacology. In: Katzung BG, editor. Basic and clinical pharmacology. 9th ed. Norwalk, CN: Appleton and Lange; 2006. p.102-110.
19. Smith GJ, Lefebvre RA. Nonadrenergic noncholinergic responses in the rat ileum. Eur J Pharmacol. 1996;303:79-87.
20. Smith GJM, Lefebvre RA. ATP and nitric oxide: inhibitory NANC neurotransmitters in the longitudinal muscle-myenteric plexus preparation of rat ileum. Br J Pharmacol. 1996;118:695-703. (Pubitemid 26180984)
21. Ekblad E, Sundler F. Motor responses in rat ileum evoked by nitric oxide donors vs. field stimulation: Modulation by pituitary adenylate cyclase activating peptide, forskolin and guanylate cyclase inhibitors. J Pharmacol Exp Ther. 1997;283:23-28. (Pubitemid 27438942)
22. Kurjak M, Sattler V, Schusdiarra V, Allwscher HD. Characterization of prejunctional and postjunctional muscarinic receptors of the ascending reflex contraction in rat ileum. J Pharmacol Exp Ther. 1999;290:893-900. (Pubitemid 29344590)
23. Storr M, Thammer J, Dunkel R, Schusdziarra V, Allescher HD. Modulatory effect of adenosine receptors on the ascending and descending neural reflex responses of rat ileum. BMC Neurosci. 2002;3:21-27.
24. Yamaji M, Ohta M, Yamazaki Y, Fujinami K, Fujita A, Takeuchi T, et al. A possible role of neurotensin in NANC relaxation of longitudinal muscle of the jejunum and ileum of Wistar rats. Br J Pharmacol. 2002;137:629-636. (Pubitemid 35333088)
25. 2+ for muscarinic receptor-induced contraction in rat ileum. J Pharm Pharmacol. 1996;48:817-819.
26. Goyal RK. Identification, localisation and classification of muscarinic receptor subtypes in the gut. Life Sci. 1988;43:2209-2220. (Pubitemid 19015224)
27. Levey AI. Immunological localization of M1-M5 muscarinic acetylcholine receptors in peripheral tissue and brain. Life Sci. 1993;52:441-448.
28. Caulfield MP. Muscarinic receptor characterization, coupling and function. Pharmacol Ther. 1993;58:319-379. (Pubitemid 23273186)
29. Eglen RM, Hege SS, Watson N. Muscarinic receptor subtypes and smooth muscle function. Pharmacol Rev. 1996;48:531-565. (Pubitemid 27023820)
30. Rang HP, Dale MM, Cholinergic transmission. In: Rang HP, Dale MM, Ritter JM, Flower RJ, editors. Rang & Dale's Pharmacology. 6th ed. London: Churchill Livingstone; 2007. p. 153.
31. Rang HP, Dale MM. How drugs act: cellular aspects-excitation, contraction and secretion. In: Rang HP, Dale MM, Ritter JM, Flower RJ, editors. Rang & Dale's Pharmacology. 6th ed. London: Churchill Livingstone; 2007. p. 54-71.
32. Reynolds IJ, Gould RJ, Snyder SH. Loperamide: blocked of calcium channels as a mechaninsm for anti-diarrheal effect. J Pharmacol Exp Ther. 1984; 231:628-632. (Pubitemid 15178976)