Characterization of prejunctional and postjunctional muscarinic receptors of the ascending reflex contraction in rat ileum

Journal of Pharmacology and Experimental Therapeutics

Volumn 290, Issue 2, 1999, Pages 893-900

  Kurjak, M ^a   Sattler, D ^a   Schusdziarra, V ^a   Allescher, H D ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DARIFENACIN; HEXAHYDROSILADIFENIDOL; METHOCTRAMINE; METHYLSCOPOLAMINE; MUSCARINIC M2 RECEPTOR; MUSCARINIC RECEPTOR; PIRENZEPINE; TRIPITRAMINE;

ANIMAL TISSUE; ARTICLE; CHOLINERGIC TRANSMISSION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; ILEUM; INTESTINE CONTRACTION; ISOTOPE LABELING; LIGAND BINDING; MALE; MUSCLE FIBER MEMBRANE; MYENTERIC PLEXUS; NEUROMUSCULAR SYNAPSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN LOCALIZATION; RAT;

ANIMALS; BINDING SITES; BINDING, COMPETITIVE; ELECTRIC STIMULATION; ILEUM; INTERCELLULAR JUNCTIONS; KINETICS; MALE; MUSCARINIC ANTAGONISTS; MUSCLE CONTRACTION; MUSCLE, SMOOTH; N-METHYLSCOPOLAMINE; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, MUSCARINIC; REFLEX; SUBCELLULAR FRACTIONS; SYNAPTOSOMES;

EID: 0032806122     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Allescher HD, Sattler D, Piller C, Schusdziarra V and Classen M (1992) Ascending neural pathways in the rat ileum in vitro: Effect of capsaicin and involvement of nitric oxide. Eur J Pharmacol 217:153-162.
2. 3H-Saxitoxin as a marker for canine muscular plexus neurons. Am J Physiol 255:G462-G469.
3. 3 antagonists for clinical use. Life Sci 60:1053-1060.
4. 3 receptor antagonist effects of a new pirenzepine analogue in isolated guinea-pig ileal longitudinal muscle-myenteric plexus. Eur J Pharmacol 254:151-157.
5. Barocelli E, Chiavarini M, Ballabeni V, Bordi F and Impicciatore M (1993) Interaction of selective compounds with muscarinic receptors at dispersed intestinal smooth muscle cells. Br J Pharmacol 108:393-397.
6. Bayliss WM and Starling EH (1899) The movements and innervation of the small intestine. J Physiol (Lond) 24:99-143.
7. 3 muscarinic receptors. Life Sci 60:1121-1128.
8. Brunner F (1989) Subclassification of atrial and intestinal muscarinic receptors of the rat: Direct binding studies with agonists and antagonists. Br J Pharmacol 97:572-578.
9. Candell LM, Yun SH, Tran LLP and Ehlert FJ (1990) Differential coupling of subtypes of the muscarinic receptor to adenylyl cyclase and phosphoinositide hydrolysis in the longitudinal muscle of the rat ileum. Mol Pharmacol 38:689-697.
10. 50) of an enzymatic reaction. Biochem Pharmacol 22:3099-3108.
11. Costa M and Furness JB (1976) The peristaltic reflex: An analysis of the nerve pathways and their pharmacology. Arch Pharmacol 294:47-60.
12. 3 muscarinic receptors in the circular muscle of the guinea-pig ileum. Naunyn-Schmiedeberg's Arch Pharmacol 351:237-243.
13. Doods HH, Enzeroth M, Ziegler H, Mayer N and Holzer P (1994) Pharmacological profile of selective muscarinic receptor antagonists on guinea-pig ileal smooth muscle. Eur J Pharmacol 253:275-281.
14. Dörje P, Levey AI and Brann MR (1991) Immunological detection of muscarinic receptor subtype proteins (m1-m5) in rabbit tissue. Mol Pharmacol 40:459-462.
15. Eglen RM and Watson N (1996) Selective muscarinic receptor agonists and antagonists. Pharmacol Toxicol 78:59-68.
16. Eglen RM, Hedge SS and Watson N (1996) Muscarinic receptor subtypes and smooth muscle function. Pharmacol Rev 48:531-565.
17. 2+ for muscarinic receptor-induced contraction in the rat ileum. J Pharm Pharmacol 48:817-819.
18. Ford APDW, Levine WB, Baxter GS, Harris GC, Eglen RM and Whiting RL (1991) Pharmacological, biochemical and molecular characterization of muscarinic receptors in the guinea-pig ileum: A multidisciplinary study. Mol Neuropharmacol 1:117-127.
19. Furness JB, Johnson P, Pompolo S and Bornstein JC (1995) Evidence that enteric motility reflexes can be initiated through entirely intrinsic mechanisms in the small intestine. Neurogastroenterol Motil 7:89-96.
20. Giraldo E, Monferini E, Ladinsky M and Hammer R (1987) Muscarinic receptor heterogeneity in guinea pig intestinal smooth muscle: Binding studies with AF-DX 116. Eur J Pharmacol 141:475-477.
21. Holzer P (1989) Ascending enteric reflex: Multiple neurotransmitter systems and interactions. Am J Physiol 256:G540-G545.
22. Holzer P, Schluet W and Maggi CA (1993) Ascending enteric reflex contraction: Roles for acetylcholine and tachykinins in relation to distension and propagation of excitation. J Pharmacol Exp Ther 264:391-396.
23. Johnson PI, Bornstein JC, Yuan SY and Furness JB (1996) Analysis of contributions of acetylcholine and tachykinins to neuro-neuronal transmission in motility reflexes in the guinea-pig ileum. Br J Pharmacol 118:973-983.
24. Kilbinger H and Nafziger M (1985) Two types of neuronal muscarine receptors modulating acetylcholine release from guinea pig myenteric plexus. Naunyn-Schmiedeberg's Arch Pharmacol 328:304-309.
25. Kosterlitz HW and Lees GM (1964) Pharmacological analysis of intrinsic intestinal reflexes. Pharmacol Rev 16:301-339.
26. Kostka P, Ahmad S, Kwan C, Daniel EE, Gordon RK and Chiang PK (1992) Prejunctional muscarinic receptors in the deep muscular plexus of canine ileum: Comparison with smooth muscle receptors. J Pharmacol Exp Ther 263:226-231.
27. Kostka P, Kwan C and Daniel EE (1989) Presynaptic and postjunctional muscarinic receptors in dog ileum: Binding studies. Eur J Pharmacol 173:35-42.
28. Kurjak M, Allescher HD, Schusdziarra V and Classen M (1994) Release of bombesin-like immunoreactivity from synaptosomes isolated from the rat ileum. Eur J Pharmacol 257:169-179.
29. Lambrecht G, Feifel R, Wagner-Roder M, Strohmann C, Zilch H, Tacke R, Waelbroeck M, Christophe J, Boddeke H and Mutschler E (1989) Affinity profiles of hexahydro-sila-difenidol analogues at muscarinic receptor subtypes. Eur J Pharmacol 168:71-78.
30. Lambrecht G, Gross J, Hacksell U, Hermanni U, Hildebrandt C, Hou X, Moser U, Nilsson BM, Pfaff O, Waelbroeck M, Wehrle J and Mutschler E (1995) The design and pharmacology of novel selective muscarinic agonists and antagonists. Life Sci 56:815-822.
31. 2-subtype antagonists. Br J Pharmacol 98:309-317.
32. Liebmann C, Nawrath S, Schnittler M, Schubert H and Jakobs KH (1992) Binding characteristics and functional G protein coupling of muscarinic acetylcholine receptors in rat duodenum smooth muscle membranes. Naunyn-Schmiedeberg's Arch Pharmacol 345:7-15.
33. Lowry OH, Rosenbrough NJ, Farr AL and Randall RJ (1951) Protein measurement with the folin phenol reagent. J Biol Chem 193:265-275.
34. Maggio R, Barbier ML, Bolognesi A, Minarini A, Tedeschi D and Melchiorre C (1994) Binding profile of the selective muscarine receptor antagonist tripitramine. Eur J Pharmacol 268:459-462.
35. Maeda A, Kubo M, Mishina M and Numa S (1988) Tissue distribution of mRNAs encoding muscarinic acetylcholine receptor subtypes. FEBS Lett 239:339-342.
36. 2 muscarinic receptors in longitudinal ileal smooth muscle membranes. Eur J Pharmacol 145:305-311.
37. 2 muscarinic receptor in smooth muscle of guinea pig ileum. Mol Pharmacol 44:102-110.
38. Tonini M and Costa M (1990) A pharmacological analysis of the neuronal circuitry involved in distension-evoked enteric excitator reflex. Neuroscience 38:787-795.
39. 2 receptor antagonist, on muscarinic and nicotinic cholinoceptors in guinea-pig airways in vivo and in vitro. Br J Pharmacol 105:107-112.