Structural and functional characterization of Rv2966c protein reveals an RsmD-like methyltransferase from Mycobacterium tuberculosis and the role of its N-terminal domain in target recognition

Journal of Biological Chemistry

Volumn 286, Issue 22, 2011, Pages 19652-19661

  Kumar, Atul ^a   Saigal, Kashyap ^b   Malhotra, Ketan ^b   Sinha, Krishna Murari ^b   Taneja, Bhupesh ^a  

^a CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

^b Institute of Molecular Medicine   (India)

Author keywords

[No Author keywords available]

Indexed keywords

C-TERMINAL DOMAINS; CELLULAR GROWTH; E. COLI; FUNCTIONAL CHARACTERIZATION; FUNCTIONAL DOMAINS; IN-VITRO; M. TUBERCULOSIS; METHYLTRANSFERASES; MYCOBACTERIUM TUBERCULOSIS; N-TERMINAL DOMAINS; N-TERMINALS; ORTHOLOGS; STRUCTURE DETERMINATION; TARGET RECOGNITION; TWO-DOMAIN STRUCTURES;

ALKYLATION; ESCHERICHIA COLI; RNA; SUBSTRATES;

PROTEINS;

BACTERIAL ENZYME; BACTERIAL PROTEIN; RIBOSOME PROTEIN; RNA 16S; RSMD LIKE METHYLTRANSFERASE; RSMD PROTEIN; RV2966C PROTEIN; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL CELL; BACTERIAL GENE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; GENE DELETION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; ORTHOLOGY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN RNA BINDING; PROTEIN STRUCTURE; PROTEIN TARGETING; RSMD GENE;

BACTERIAL PROTEINS; HISTONES; METHYLATION; MYCOBACTERIUM TUBERCULOSIS; PROTEIN STRUCTURE, TERTIARY; RNA, BACTERIAL; RNA, RIBOSOMAL, 16S; STRUCTURE-ACTIVITY RELATIONSHIP; TRNA METHYLTRANSFERASES;

CORYNEBACTERINEAE; ESCHERICHIA COLI; MYCOBACTERIUM TUBERCULOSIS;

EID: 79957588857     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.200428     Document Type: Article

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