Mesenchymal, but not hematopoietic, stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction in mice

Kidney International

Volumn 68, Issue 5, 2005, Pages 1940-1943

  Fukuda, Keiichi ^a   Fujita, Jun ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTININ; ENHANCED GREEN FLUORESCENT PROTEIN; GRANULOCYTE COLONY STIMULATING FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BONE MARROW; BONE MARROW TRANSPLANTATION; CELL DIFFERENTIATION; CELL LINEAGE; CELL POPULATION; CONFERENCE PAPER; CONTROLLED STUDY; HEART INFARCTION; HEART MUSCLE CELL; HEMATOPOIETIC STEM CELL; IRRADIATION; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL MOBILIZATION; TRANSGENIC MOUSE;

ANIMALS; CELL DIFFERENTIATION; HEMATOPOIETIC STEM CELL MOBILIZATION; HEMATOPOIETIC STEM CELLS; MESODERM; MICE; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; REGENERATION;

EID: 30944448824     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1111/j.1523-1755.2005.00624.x     Document Type: Conference Paper

References (18)

1. WEISSMAN IL, ANDERSON DJ, GAGE F: Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations. Ann Rev Cell Dev Biol 17:387-403, 2001
2. ORLIC D, KAJSTURA J, CHIMENTI S, et al: Bone marrow cells regenerate infarcted myocardium. Nature 410:701-705, 2001
3. JACKSON KA, MAJKA SM, WANG H, et al: Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells. J Clin Invest 107:1395-1402, 2001
4. ORLIC D, KAJSTURA J, CHIMENTI S, et al: Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc Natl Acad Sci USA 98:10344-10349, 2001
5. MAKINO S, FUKUDA K, MIYOSHI S, et al: Cardiomyocytes can be generated from marrow stromal cells in vitro. J Clin Invest 103:697-705, 1999
6. HAKUNO D, FUKUDA K, MAKINO S, et al: Bone marrow-derived cardiomyocytes (CMG cell) expressed functionally active adrenergic and muscarinic receptors. Circulation 105:380-386, 2002
7. TOMA C, PITTENGER MF, CAHILL KS, et al: Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart. Circulation 105:93-98, 2002
8. TOMITA S, LI RK, WEISEL RD, et al: Autologous transplantation of bone marrow cells improves damaged heart function. Circulation 100(Suppl):II247- II256, 1999
9. ALVAREZ-DOLADO M, PARDAL R, GARCIA-VERDUGO JM, et al: Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes. Nature 425:968-973, 2003
10. MURRY CE, SOONPAA MH, REINECKE H, et al: Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts. Nature 428:664-668, 2004
11. BALSAM LB, WAGERS AJ, CHRISTENSEN JL, et al: Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium. Nature 428:668-673, 2004
12. MATSUZAKI Y, KINJO K, MULLIGAN RC, OKANO H: Unexpectedly efficient homing capacity of purified murine hematopoietic stem cells. Immunity 20:87-93, 2004
13. HATTAN N, KAWAGUCHI H, ANDO K, et al: Purified cardiomyocytes from bone marrow mesenchymal stem cells produce stable intracardiac grafts in mice. Cardiovasc Res 65:334-344, 2005.
14. ROMBOUTS WJC, PLOEMACHER RE: Primary murine MSC show highly efficient homing to the bone marrow but lose homing ability following culture. Leukemia 17:160-170, 2003
15. KOCHER AA, SCHUSTER MD, SZABOLCS MJ, et al: Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat Med 7:430-436, 2001
16. LAPIDOT T, PETIT I: Current understanding of stem cell mobilization: the roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells. Exp Hematol 30:973-981, 2002
17. PROCKOP DJ: Marrow stromal cells as stem cells for nonhematopoietic tissues. Science 276:71-74, 1997
18. ZHAO Y, GLESNE D, HUBERMAN E: A human peripheral blood monocyte-derived subset acts as pluripotent stem cells. Proc Natl Acad Sci USA 100:2426-2431, 2003