Acute high-dose X-radiation-induced genomic changes in A549 cells

Radiation Research

Volumn 175, Issue 6, 2011, Pages 700-707

  Muradyan, A ^a   Gilbertz, K ^b   Stabentheiner, S ^a   Klause, S ^b   Madle, H ^a   Meineke, V ^b   Ullmann, R ^a   Scherthan, H ^a,b  

^a MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^b Institut fur Radiobiologie der Bundeswehr   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE STRESS; ARTICLE; CANCER CELL; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL LEVEL; CELL STRAIN A549; CELL SURVIVAL; CHROMOSOME ABERRATION; CHROMOSOME NUMBER; CHROMOSOME PAINTING; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; COPY NUMBER VARIATION; DILUTION; GENE EXPRESSION; HUMAN; HUMAN CELL; IONIZING RADIATION; LUNG NON SMALL CELL CANCER; MALE; PRIORITY JOURNAL; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; RADIOSENSITIVITY; TRANSCRIPTION INITIATION;

CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; CHROMOSOME ABERRATIONS; COMPARATIVE GENOMIC HYBRIDIZATION; GENE DOSAGE; GENE EXPRESSION; GENOME, HUMAN; GENOMIC INSTABILITY; HUMANS; RADIATION TOLERANCE; X-RAYS;

EID: 79957581280     PISSN: 00337587     EISSN: 19385404     Source Type: Journal    
DOI: 10.1667/RR2341.1     Document Type: Article

References (40)

1. J-C. Nénot, Radiation accidents over the last 60 years. J. Radiol. Prot. 29, 301-320 (2009).
2. R. Born, J. Kummermehr, J. Griebel and K. R. Trott, The proliferative capacity of mouse fibrosarcoma cells that survived x-irradiation. Radiat. Environ. Biophys. 34, 233-237 (1995). (Pubitemid 26003612)
3. A. S. Tarnawski and M. K. Jones, The role of epidermal growth factor (EGF) and its receptor in mucosal protection, adaptation to injury, and ulcer healing: involvement of EGF-R signal transduction pathways. J. Clin. Gastroenterol. 27 (Suppl. 1), S12-S20 (1998). (Pubitemid 29028869)
4. S. A. Amundson and A. J. Fornace, Gene expression profiles for monitoring radiation exposure. Radiat. Prot. Dosimetry 97, 11-16 (2001). (Pubitemid 33094848)
5. S. A. Amundson, K. T. Do, L. C. Vinikoor, R. A. Lee, C. A. Koch-Paiz, J. Ahn, M. Reimers, Y. Chen, D. A. Scudiero and A. J. Fornace, Integrating global gene expression and radiation survival parameters across the 60 cell lines of the National Cancer Institute Anticancer Drug Screen. Cancer Res. 68, 415-424 (2008). (Pubitemid 351380067)
6. F. Zhang, W. Gu, M. E. Hurles and J. R. Lupski, Copy number variation in human health, disease, and evolution. Annu. Rev. Genomics Hum. Genet. 10, 451-481 (2009).
7. A. Riches, C. Peddie, S. Rendell, P. Bryant, H. Zitzelsberger, J. Bruch, J. Smida, L. Hieber and M. Bauchinger, Neoplastic transformation and cytogenetic changes after gamma irradiation of human epithelial cells expressing telomerase. Radiat. Res. 155, 222-229 (2001). (Pubitemid 33723542)
8. E. G. Wright, Inherited and inducible chromosomal instability: a fragile bridge between genome integrity mechanisms and tumourigenesis. J. Pathol. 187, 19-27 (1999). (Pubitemid 29009832)
9. C. L. Limoli, B. Ponnaiya, J. J. Corcoran, E. Giedzinski, M. I. Kaplan, A. Hartmann and W. F. Morgan, Genomic instability induced by high and low LET ionizing radiation. Adv. Space Res. 25, 2107-2117 (2000).
10. Z. Somodi, N. A. Zyuzikov, G. Kashino, K. R. Trott and K. M. Prise, Radiation-induced genomic instability in repair deficient mutants of Chinese hamster cells. Int. J. Radiat. Biol. 81, 929-936 (2005). (Pubitemid 43361950)
11. R. J. Preston, Bystander effects, genomic instability, adaptive response, and cancer risk assessment for radiation and chemical exposures. Toxicol. Appl. Pharmacol. 207, 550-556 (2005).
12. J. D. Tucker, Fish cytogenetics and the future of radiation biodosimetry. Radiat. Prot. Dosimetry 97, 55-60 (2001). (Pubitemid 33094854)
13. Y. Murakami, T. Nobukuni, K. Tamura, T. Maruyama, T. Sekiya, Y. Arai, H. Gomyou, A. Tanigami, M. Ohki and R. H. Reeves, Localization of tumor suppressor activity important in nonsmall cell lung carcinoma on chromosome 11q. Proc. Natl. Acad. Sci. USA 95, 8153-8158 (1998). (Pubitemid 28326082)
14. K. Hirai, H. Shimada, T. Ogawa and S. Taji, The spread of human lung cancer cells on collagens and its inhibition by type III collagen. Clin. Exp. Metastasis 9, 517-527 (1991).
15. D. M. Valenzuela and J. Groffen, Four human carcinoma cell lines with novel mutations in position 12 of c-K-ras oncogene. Nucleic Acids Res. 14, 843-852 (1986). (Pubitemid 16136140)
16. T. Isaka, A. L. Nestor, T. Takada and D. C. Allison, Chromosomal variations within aneuploid cancer lines. J. Histochem. Cytochem. 51, 1343-1353 (2003). (Pubitemid 37187586)
17. M. Lieber, B. Smith, A. Szakal, W. Nelson-Rees and G. Todaro, A continuous tumor-cell line from a human lung carcinoma with properties of type II alveolar epithelial cells. Int. J. Cancer 17, 62-70 (1976).
18. J. Lu-Hesselmann, M. Abend and D. van Beuningen, Comparison of endogenous TP53 genomic status with clonogenicity and different modes of cell death after X irradiation. Radiat. Res. 161, 39-47 (2004). (Pubitemid 38018722)
19. K. P. Gilbertz, D. van Beuningen and A. P. Rhein, Early changes in cell cycle kinetics after ionizing irradiation below 1 Gy. Int. J. Radiat. Biol. 73, 187-195 (1998). (Pubitemid 28104410)
20. M. Abend, K. Kehe, K. Kehe, M. Riedel and D. Van Beuningen, Correlation of micronucleus and apoptosis assays with reproductive cell death can be improved by considering other modes of death. Int. J. Radiat. Biol. 76, 249-259 (2000). (Pubitemid 30093472)
21. T. Maniatis, E. F. Fritsch and J. Sambrook, Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1982.
22. S. Knehr, R. Huber, H. Braselmann, H. Schraube and M. Bauchinger, Multicolour FISH painting for the analysis of chromosomal aberrations induced by 220 kV X-rays and fission neutrons. Int. J. Radiat. Biol. 75, 407-418 (1999). (Pubitemid 29191538)
23. H. Scherthan, M. Abend, K. Muller, C. Beinke, H. Braselmann, H. Zitzelsberger, F. M. Kohn, H. Pillekamp, R. Schiener and V. Meineke, Radiation-induced late effects in two affected individuals of the Lilo radiation accident. Radiat. Res. 167, 615-623 (2007). (Pubitemid 351292969)
24. F. Erdogan, R. Ullmann, W. Chen, M. Schubert, S. Adolph, C. Hultschig, V. Kalscheuer, H. H. Ropers, C. Spaich and A. Tzschach, Characterization of a 5.3 Mb deletion in 15q14 by comparative genomic hybridization using a whole genome "tiling path" BAC array in a girl with heart defect, cleft palate, and developmental delay. Am. J. Med. Genet. A 143, 172-178 (2007). (Pubitemid 46047672)
25. M. Krzywinski, I. Bosdet, D. Smailus, R. Chiu, C. Mathewson, N. Wye, S. Barber, M. Brown-John, S. Chan and M. A. Marra, A set of BAC clones spanning the human genome. Nucleic Acids Res. 32, 3651-3660 (2004). (Pubitemid 39157714)
26. K. Osoegawa, A. G. Mammoser, C. Wu, E. Frengen, C. Zeng, J. J. Catanese and P. J. de Jong, A bacterial artificial chromosome library for sequencing the complete human genome. Genome Res. 11, 483-496 (2001). (Pubitemid 32243858)
27. W. Chen, F. Erdogan, H. H. Ropers, S. Lenzner and R. Ullmann, CGHPRO - a comprehensive data analysis tool for array CGH. BMC Bioinformatics 6, 85 (2005).
28. S. Y. Park, H. C. Choi, Y. H. Chun, H. Kim and S. H. Park, Characterization of chromosomal aberrations in lung cancer cell lines by cross-species color banding. Cancer Genet. Cytogenet. 124, 62-70 (2001). (Pubitemid 32101472)
29. M. Cottier, A. Tchirkov, B. Perissel, M. Giollant, L. Campos and P. Vago, Cytogenetic characterization of seven human cancer cell lines by combining G- and R-banding, M-FISH, CGH and chromosome- and locus-specific FISH. Int. J. Mol. Med. 14, 483-495 (2004).
30. M. Ahmadian, I. I. Wistuba, K. M. Fong, C. Behrens, D. R. Kodagoda, M. H. Saboorian, J. Shay, G. E. Tomlinson, J. Blum and A. F. Gazdar, Analysis of the FHIT gene and FRA3B region in sporadic breast cancer, preneoplastic lesions, and familial breast cancer probands. Cancer Res. 57, 3664-3668 (1997). (Pubitemid 27381204)
31. L. Ji, B. Fang, N. Yen, K. Fong, J. D. Minna and J. A. Roth, Induction of apoptosis and inhibition of tumorigenicity and tumor growth by adenovirus vector-mediated fragile histidine triad (FHIT) gene overexpression. Cancer Res. 59, 3333-3339 (1999). (Pubitemid 29334487)
32. L. Roz, M. Gramegna, H. Ishii, C. M. Croce and G. Sozzi, Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in lung and cervical cancer cell lines. Proc. Natl. Acad. Sci. USA 99, 3615-3620 (2002). (Pubitemid 34252155)
33. M. Fabbri, D. Iliopoulos, F. Trapasso, R. I. Aqeilan, A. Cimmino, N. Zanesi, S. Yendamuri, S. Y. Han, D. Amadori and C. M. Croce, WWOX gene restoration prevents lung cancer growth in vitro and in vivo. Proc. Natl. Acad. Sci. USA 102, 15611-15616 (2005). (Pubitemid 41528104)
34. S. P. Finn, P. Smyth, E. O'Regan, S. Cahill, R. Flavin, J. O'Leary and O. Sheils, Array comparative genomic hybridisation analysis of gamma-irradiated human thyrocytes. Virchows Arch. 445, 396-404 (2004). (Pubitemid 39517766)
35. J. B. Little, H. Nagasawa, T. Pfenning and H. Vetrovs, Radiation-induced genomic instability: delayed mutagenic and cytogenetic effects of X rays and alpha particles. Radiat. Res. 148, 299-307 (1997). (Pubitemid 27435629)
36. G. Varma, R. Varma, H. Huang, A. Pryshchepava, J. Groth, D. Fleming, N. J. Nowak, D. McQuaid, J. Conroy and J. Geradts, Array comparative genomic hybridisation (aCGH) analysis of premenopausal breast cancers from a nuclear fallout area and matched cases from Western New York. Br. J. Cancer 93, 699-708 (2005). (Pubitemid 41486462)
37. S. G. Durkin and T. W. Glover, Chromosome fragile sites. Annu. Rev. Genet. 41, 169-192 (2007).
38. D. Iliopoulos, G. Guler, S. Y. Han, T. Druck, M. Ottey, K. A. McCorkell and K. Huebner, Roles of FHIT and WWOX fragile genes in cancer. Cancer Lett. 232, 27-36 (2006). (Pubitemid 43053931)
39. S. G. Durkin, R. L. Ragland, M. F. Arlt, J. G. Mulle, S. T. Warren and T. W. Glover, Replication stress induces tumor-like microdeletions in FHIT/FRA3B. Proc. Natl. Acad. Sci. USA 105, 246-251 (2008).
40. L. Barrios, R. Miro, M. R. Caballin, C. Fuster, F. Guedea, A. Subias and J. Egozcue, Cytogenetic effects of radiotherapy. Breakpoint distribution in induced chromosome aberrations. Cancer Genet. Cytogenet. 41, 61-70 (1989). (Pubitemid 19247992)