Formulation development and optimization of alpha ketoglutarate nanoparticles for cyanide poisoning

Powder Technology

Volumn 211, Issue 1, 2011, Pages 1-9

  Sultana, Shaheen ^a   Talegaonkar, Sushama ^a   Ali, Raisuddin ^b   Mittal, Gaurav ^b   Bhatnagar, Aseem ^b   Ahmad, Farhan J ^a  

^a HAMDARD UNIVERSITY   (India)

^b INSTITUTE OF NUCLEAR MEDICINE AND ALLIED SCIENCES   (India)

Author keywords

Alpha ketoglutarate; Box Behnken statistical design; Lutrol; Nanoparticles

Indexed keywords

AVERAGE PARTICLE SIZE; BOX-BEHNKEN; COSOLVENTS; CRYSTAL GROWTH INHIBITORS; CYANIDE POISONING; DRUG CONCENTRATION; DRY POWDER INHALER; FORMULATION DEVELOPMENT; INDEPENDENT VARIABLES; KETOGLUTARATE; LUTROL; NANO-SIZED PARTICLES; NON-POLYMERIC; PARTICLE CHARACTERIZATION; STATISTICAL DESIGN; STIRRING SPEED;

CONCENTRATION (PROCESS); CRYSTAL GROWTH; CYANIDES; DIFFERENTIAL SCANNING CALORIMETRY; ENGINEERING RESEARCH; FOURIER TRANSFORM INFRARED SPECTROSCOPY; NANOPARTICLES; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OPTIMIZATION; PARTICLE SIZE; RESONANCE; SOLVENTS; X RAY DIFFRACTION; X RAY DIFFRACTION ANALYSIS;

PRECIPITATION (CHEMICAL);

2 OXOGLUTARIC ACID; NANOPARTICLE; POLOXAMER; POLYVINYL ALCOHOL; SOLVENT; STABILIZING AGENT;

ARTICLE; CYANIDE POISONING; DIFFERENTIAL SCANNING CALORIMETRY; DRUG FORMULATION; DRUG SCREENING; INFRARED SPECTROSCOPY; NUCLEAR MAGNETIC RESONANCE; PARTICLE SIZE; POWDER INHALER; PRECIPITATION; PREDICTION; PROCESS OPTIMIZATION; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY; X RAY DIFFRACTION; ZETA POTENTIAL;

EID: 79957519114     PISSN: 00325910     EISSN: 1873328X     Source Type: Journal    
DOI: 10.1016/j.powtec.2011.01.012     Document Type: Article

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