JC virus variant associated with cerebellar atrophy in a patient with AIDS

Journal of Clinical Microbiology

Volumn 49, Issue 6, 2011, Pages 2196-2199

  Roux, Damien ^a   Bouldouyre, Marie Anne ^a   Mercier Delarue, Séverine ^a   Seilhean, Danielle ^b   Zagdanski, Anne Marie ^a   Delaugerre, Constance ^a   Simon, François ^a   Molina, Jean Michel ^a   Legoff, Jerôme ^a  

^a SAINT LOUIS HOSPITAL   (France)

^b SORBONNE UNIVERSITÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

EMTRICITABINE; LOPINAVIR; RITONAVIR; TENOFOVIR;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ARTICLE; ATAXIA; CACHEXIA; CASE REPORT; CD4+ T LYMPHOCYTE; CEREBELLUM ATROPHY; CEREBELLUM DISEASE; CONFUSION; CYTOMEGALOVIRUS; DEATH; DISEASE ASSOCIATION; DISEASE EXACERBATION; DYSARTHRIA; GENETIC VARIABILITY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; JC VIRUS; KINETIC TREMOR; MALE; MYCOBACTERIUM AVIUM; NYSTAGMUS; PRIORITY JOURNAL; TREATMENT RESPONSE; TREMOR;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ADULT; ATROPHY; CEREBELLAR DISEASES; CEREBROSPINAL FLUID; CEREBRUM; DNA, VIRAL; GENE REARRANGEMENT; HEAD; HISTOCYTOCHEMISTRY; HUMANS; IMMUNOHISTOCHEMISTRY; JC VIRUS; LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL; MAGNETIC RESONANCE IMAGING; MALE; MICROSCOPY; POLYOMAVIRUS INFECTIONS; REGULATORY SEQUENCES, NUCLEIC ACID; TUMOR VIRUS INFECTIONS; URINE;

HUMAN IMMUNODEFICIENCY VIRUS; JC POLYOMAVIRUS;

EID: 79957496469     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.02057-10     Document Type: Article

References (19)

1. Dang, X., and I. J. Koralnik. 2006. A granule cell neuron-associated JC virus variant has a unique deletion in the VP1 gene. J. Gen. Virol. 87:2533-2537.
2. Del Valle, L., and S. Pina-Oviedo. 2006. HIV disorders of the brain: pathology and pathogenesis. Front. Biosci. 11:718-732.
3. Du Pasquier, R. A., et al. 2003. Productive infection of cerebellar granule cell neurons by JC virus in an HIV+ individual. Neurology 61:775-782. (Pubitemid 37174472)
4. Frisque, R. J., G. L. Bream, and M. T. Cannella. 1984. Human polyomavirus JC virus genome. J. Virol. 51:458-469.
5. Gosert, R., P. Kardas, E. O. Major, and H. H. Hirsch. 2010. Rearranged JC virus noncoding control regions found in progressive multifocal leukoencephalopathy increase virus early gene expression and replication rate. J. Virol. 84:10448-10456.
6. Herman, J., et al. 2004. Polyomavirus infection in pediatric renal transplant recipients: evaluation using a quantitative real-time PCR technique. Pediatr. Transplant. 8:485-492.
7. Iida, T., et al. 1993. Origin of JC polyomavirus variants associated with progressive multifocal leukoencephalopathy. Proc. Natl. Acad. Sci. U. S. A. 90:5062-5065.
8. Jensen, P. N., and E. O. Major. 2001. A classification scheme for human polyomavirus JCV variants based on the nucleotide sequence of the non-coding regulatory region. J. Neurovirol. 7:280-287.
9. Koralnik, I. J., et al. 2005. JC virus granule cell neuronopathy: a novel clinical syndrome distinct from progressive multifocal leukoencephalopathy. Ann. Neurol. 57:576-580.
10. Marzocchetti, A., et al. 2007. Characterization of JC virus in cerebrospinal fluid from HIV infected patients with progressive multifocal leukoencephalopathy: insights into viral pathogenesis and disease prognosis. J. Neurovirol. 13:338-346. (Pubitemid 47400032)
11. Messam, C. A., J. Hou, R. M. Gronostajski, and E. O. Major. 2003. Lineage pathway of human brain progenitor cells identified by JC virus susceptibility. Ann. Neurol. 53:636-646.
12. Safak, M., G. L. Gallia, and K. Khalili. 1999. Reciprocal interaction between two cellular proteins, Puralpha and YB, modulates transcriptional activity of JCVCY in glial cells. Mol. Cell. Biol. 19:2712-2723.
13. Sugimoto, C., et al. 1998. Amplification of JC virus regulatory DNA sequences from cerebrospinal fluid: diagnostic value for progressive multifocal leukoencephalopathy. Arch. Virol. 143:249-262.
14. Sunyaev, S. R., A. Lugovskoy, K. Simon, and L. Gorelik. 2009. Adaptive mutations in the JC virus protein capsid are associated with progressive multifocal leukoencephalopathy (PML). PLoS Genet. 5:e1000368.
15. Vaz, B., P. Cinque, M. Pickhardt, and T. Weber. 2000. Analysis of the transcriptional control region in progressive multifocal leukoencephalopathy. J. Neurovirol. 6:398-409.
16. Wuthrich, C., et al. 2009. Frequent infection of cerebellar granule cell neurons by polyomavirus JC in progressive multifocal leukoencephalopathy. J. Neuropathol. Exp. Neurol. 68:15-25.
17. Yasuda, Y., et al. 2003. Comparison of PCR-amplified JC virus control region sequences from multiple brain regions in PML. Neurology 61:1617-1619. (Pubitemid 37505592)
18. Zheng, H. Y., et al. 2005. Characterization of the VP1 loop mutations wide-spread among JC polyomavirus isolates associated with progressive multifocal leukoencephalopathy. Biochem. Biophys. Res. Commun. 333:996-1002.
19. Zheng, H. Y., et al. 2005. New sequence polymorphisms in the outer loops of the JC polyomavirus major capsid protein (VP1) possibly associated with progressive multifocal leukoencephalopathy. J. Gen. Virol. 86:2035-2045.