Frequent infection of cerebellar granule cell neurons by polyomavirus JC in progressive multifocal leukoencephalopathy

Journal of Neuropathology and Experimental Neurology

Volumn 68, Issue 1, 2009, Pages 15-25

  Wüthrich, Christian ^a   Cheng, Yi Min ^a   Joseph, Jeffrey T ^b   Kesari, Santosh ^c,d   Beckwith, Curt ^e   Stopa, Edward ^f   Bell, Jeanne E ^g   Koralnik, Igor J ^a,b  

^a Division of Viral Pathogenesis   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c Brigham and Womens Hospital   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e MIRIAM HOSPITAL   (United States)

^f BROWN UNIVERSITY   (United States)

^g UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Cerebellum; Granule cell neurons; HIV; JC virus; Progressive multifocal leukoencephalopathy

Indexed keywords

BIOLOGICAL MARKER; PROTEIN VP1; VIRUS T ANTIGEN; 2',3' CYCLIC NUCLEOTIDE 3' PHOSPHODIESTERASE; CAPSID PROTEIN; ENOLASE; MAP2 PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; VIRUS PROTEIN;

ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; BRAIN NERVE CELL; CELL COUNT; CENTRAL NERVOUS SYSTEM INFECTION; CEREBELLUM; CLINICAL ARTICLE; CONTROLLED STUDY; DEMYELINATION; FEMALE; GRANULE CELL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN TISSUE; IMMUNOCOMPROMISED PATIENT; IMMUNOHISTOCHEMISTRY; JC VIRUS; MALE; PREVALENCE; PRIORITY JOURNAL; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; PROTEIN EXPRESSION; VIRUS INFECTION; VIRUS PATHOGENESIS; WHITE MATTER; ACQUIRED IMMUNE DEFICIENCY SYNDROME; DEMYELINATING DISEASE; METABOLISM; METHODOLOGY; MIDDLE AGED; NERVE CELL; PATHOGENICITY; PATHOLOGY; VIROLOGY;

2',3'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES; ACQUIRED IMMUNODEFICIENCY SYNDROME; ADULT; AGED; ANTIGENS, VIRAL, TUMOR; CAPSID PROTEINS; CELL COUNT; CEREBELLUM; DEMYELINATING DISEASES; FEMALE; HUMANS; JC VIRUS; LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MIDDLE AGED; NEURONS; PHOSPHOPYRUVATE HYDRATASE; VIRAL STRUCTURAL PROTEINS;

EID: 64049119421     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/NEN.0b013e3181912570     Document Type: Article

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